GENE
LOGIC INC.
(in
thousands, except share data)
|
|
September
30,
|
|
|
December
31,
|
|
|
|
2007
|
|
|
2006
|
|
|
|
(Unaudited)
|
|
|
|
|
ASSETS
|
|
|
|
|
|
|
Current
assets:
|
|
|
|
|
|
|
Cash
and cash equivalents
|
|
$
|
22,640
|
|
|
$
|
25,700
|
|
Marketable
securities available-for-sale
|
|
|
8,917
|
|
|
|
24,410
|
|
Accounts
receivable, net of allowance of $49 and $45 as of September 30,
2007
and
|
|
|
|
|
|
|
|
|
December
31, 2006, respectively
|
|
|
615
|
|
|
|
3,327
|
|
Unbilled
services
|
|
|
602
|
|
|
|
589
|
|
Inventory,
net
|
|
|
1,156
|
|
|
|
2,180
|
|
Prepaid
expenses
|
|
|
1,592
|
|
|
|
1,260
|
|
Other
current assets
|
|
|
2,610
|
|
|
|
3,551
|
|
Total
current assets
|
|
|
38,132
|
|
|
|
61,017
|
|
Property
and equipment, net
|
|
|
10,415
|
|
|
|
12,829
|
|
Long-term
investments
|
|
|
2,964
|
|
|
|
2,964
|
|
Goodwill
|
|
|
2,677
|
|
|
|
2,677
|
|
Other
intangibles, net
|
|
|
7,122
|
|
|
|
10,060
|
|
Other
assets
|
|
|
483
|
|
|
|
726
|
|
Total
assets
|
|
$
|
61,793
|
|
|
$
|
90,273
|
|
LIABILITIES
AND STOCKHOLDERS' EQUITY
|
|
|
|
|
|
|
|
|
Current
liabilities:
|
|
|
|
|
|
|
|
|
Accounts
payable
|
|
$
|
2,383
|
|
|
$
|
3,703
|
|
Payable
to Bridge Pharmaceuticals
|
|
|
119
|
|
|
|
1,727
|
|
Accrued
compensation and employee benefits
|
|
|
4,169
|
|
|
|
2,883
|
|
Other
accrued expenses
|
|
|
2,406
|
|
|
|
3,751
|
|
Accrued
restructuring costs
|
|
|
309
|
|
|
|
1,941
|
|
Current
portion of long-term debt
|
|
|
501
|
|
|
|
499
|
|
Deferred
revenue
|
|
|
5,018
|
|
|
|
3,299
|
|
Total
current liabilities
|
|
|
14,905
|
|
|
|
17,803
|
|
Deferred
revenue
|
|
|
137
|
|
|
|
228
|
|
Long-term
debt, net of current portion
|
|
|
40
|
|
|
|
78
|
|
Deferred
rent
|
|
|
882
|
|
|
|
1,074
|
|
Total
liabilities
|
|
|
15,964
|
|
|
|
19,183
|
|
Commitments
and contingencies
|
|
|
-
|
|
|
|
-
|
|
Stockholders'
equity:
|
|
|
|
|
|
|
|
|
Preferred
stock, $.01 par value; 10,000,000 shares authorized; and no shares
issued
and
|
|
|
|
|
|
|
|
|
outstanding
as of September 30, 2007 and December 31, 2006
|
|
|
-
|
|
|
|
-
|
|
Common
stock, $.01 par value; 60,000,000 shares authorized; 32,172,588
and 31,820,273 shares
|
|
|
|
|
|
|
|
|
issued
and outstanding as of September 30, 2007 and December 31, 2006,
respectively
|
|
|
322
|
|
|
|
318
|
|
Additional
paid-in-capital
|
|
|
387,109
|
|
|
|
386,530
|
|
Accumulated
other comprehensive loss
|
|
|
(37
|
)
|
|
|
(78
|
)
|
Accumulated
deficit
|
|
|
(341,565
|
)
|
|
|
(315,680
|
)
|
Total
stockholders' equity
|
|
|
45,829
|
|
|
|
71,090
|
|
Total
liabilities and stockholders' equity
|
|
$
|
61,793
|
|
|
$
|
90,273
|
|
See
accompanying
notes.
GENE
LOGIC INC.
(in
thousands, except per share data)
(Unaudited)
|
|
Three
Months Ended
|
|
|
Nine
Months Ended
|
|
|
|
September
30,
|
|
|
September
30,
|
|
|
|
2007
|
|
|
2006
|
|
|
2007
|
|
|
2006
|
|
Revenue:
|
|
|
|
|
|
|
|
|
|
|
|
|
Genomics
services
|
|
$
|
3,684
|
|
|
$
|
3,698
|
|
|
$
|
12,356
|
|
|
$
|
17,129
|
|
Drug
repositioning services
|
|
|
841
|
|
|
|
6
|
|
|
|
879
|
|
|
|
36
|
|
Total
revenue
|
|
|
4,525
|
|
|
|
3,704
|
|
|
|
13,235
|
|
|
|
17,165
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Expenses:
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Database
production
|
|
|
5,067
|
|
|
|
6,029
|
|
|
|
15,765
|
|
|
|
21,453
|
|
Research
and development
|
|
|
2,749
|
|
|
|
2,618
|
|
|
|
7,859
|
|
|
|
7,599
|
|
Selling,
general and administrative
|
|
|
5,046
|
|
|
|
5,223
|
|
|
|
17,044
|
|
|
|
17,019
|
|
Genomics
Division restructuring
|
|
|
-
|
|
|
|
5,377
|
|
|
|
-
|
|
|
|
5,377
|
|
Total
expenses
|
|
|
12,862
|
|
|
|
19,247
|
|
|
|
40,668
|
|
|
|
51,448
|
|
Loss
from operations
|
|
|
(8,337
|
)
|
|
|
(15,543
|
)
|
|
|
(27,433
|
)
|
|
|
(34,283
|
)
|
Interest
(income), net
|
|
|
(463
|
)
|
|
|
(633
|
)
|
|
|
(1,594
|
)
|
|
|
(2,162
|
)
|
Other
(income) expense
|
|
|
32
|
|
|
|
(66
|
)
|
|
|
46
|
|
|
|
35
|
|
Write-down
of long-term equity investment
|
|
|
-
|
|
|
|
-
|
|
|
|
-
|
|
|
|
275
|
|
Loss
from continuing operations
|
|
|
(7,906
|
)
|
|
|
(14,844
|
)
|
|
|
(25,885
|
)
|
|
|
(32,431
|
)
|
Loss
from discontinued operations
|
|
|
-
|
|
|
|
(11,811
|
)
|
|
|
-
|
|
|
|
(17,307
|
)
|
Net
loss
|
|
$
|
(7,906
|
)
|
|
$
|
(26,655
|
)
|
|
$
|
(25,885
|
)
|
|
$
|
(49,738
|
)
|
Basic
and diluted net loss per share:
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Loss
from continuing operations
|
|
$
|
(0.25
|
)
|
|
$
|
(0.47
|
)
|
|
$
|
(0.81
|
)
|
|
$
|
(1.02
|
)
|
Loss
from discontinued operations
|
|
|
-
|
|
|
|
(0.37
|
)
|
|
|
-
|
|
|
|
(0.54
|
)
|
Net
loss
|
|
$
|
(0.25
|
)
|
|
$
|
(0.84
|
)
|
|
$
|
(0.81
|
)
|
|
$
|
(1.56
|
)
|
Shares
used in computing basic and diluted
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
net
loss per share
|
|
|
31,894
|
|
|
|
31,810
|
|
|
|
31,865
|
|
|
|
31,802
|
|
See
accompanying
notes.
GENE
LOGIC INC.
(in
thousands)
(Unaudited)
|
|
Nine
Months Ended
|
|
|
|
September
30,
|
|
|
|
2007
|
|
|
2006
|
|
Cash
flows from operating activities:
|
|
|
|
|
|
|
Loss
from continuing operations
|
|
$
|
(25,885
|
)
|
|
$
|
(32,431
|
)
|
Adjustments
to reconcile loss from continuing operations to net cash
flows
|
|
|
|
|
|
|
|
|
from
continuing operating activities:
|
|
|
|
|
|
|
|
|
Depreciation
and amortization
|
|
|
6,941
|
|
|
|
8,132
|
|
Non-cash
Genomics Division restructuring
|
|
|
-
|
|
|
|
5,377
|
|
Non-cash
stock compensation expense
|
|
|
573
|
|
|
|
542
|
|
Other
|
|
|
149
|
|
|
|
943
|
|
Changes
in continuing operating assets and liabilities:
|
|
|
|
|
|
|
|
|
Accounts
receivable and unbilled services
|
|
|
2,699
|
|
|
|
4,078
|
|
Inventory
|
|
|
1,024
|
|
|
|
(115
|
)
|
Prepaids
and other assets
|
|
|
852
|
|
|
|
(692
|
)
|
Accounts
payable
|
|
|
(1,320
|
)
|
|
|
(2,458
|
)
|
Accrued
expenses and deferred rent
|
|
|
(16
|
)
|
|
|
(3,729
|
)
|
Accrued
restructuring
|
|
|
(1,632
|
)
|
|
|
-
|
|
Accrued
technologies payable
|
|
|
-
|
|
|
|
(3,492
|
)
|
Deferred
revenue
|
|
|
1,628
|
|
|
|
(5,482
|
)
|
Net
cash flows from continuing operating activities
|
|
|
(14,987
|
)
|
|
|
(29,327
|
)
|
Loss
from discontinued operations
|
|
|
-
|
|
|
|
(17,307
|
)
|
Adjustments
to reconcile loss from discontinued operations to net cash
flows
|
|
|
|
|
|
|
|
|
from
discontinued operating activities:
|
|
|
|
|
|
|
|
|
Impairment
charges, depreciation and amortization and other non-cash
items
|
|
|
-
|
|
|
|
14,045
|
|
Changes
in discontinued operating assets and liabilities
|
|
|
-
|
|
|
|
1,659
|
|
Net
cash flows from discontinued operating activities
|
|
|
-
|
|
|
|
(1,603
|
)
|
Net
cash flows from operating activities
|
|
|
(14,987
|
)
|
|
|
(30,930
|
)
|
Cash
flows from investing activities:
|
|
|
|
|
|
|
|
|
Purchases
of property and equipment
|
|
|
(549
|
)
|
|
|
(1,845
|
)
|
Purchases
of licenses and patent costs
|
|
|
(424
|
)
|
|
|
(622
|
)
|
Software
development costs
|
|
|
(267
|
)
|
|
|
(882
|
)
|
Database
upgrade costs
|
|
|
(498
|
)
|
|
|
(1,974
|
)
|
Purchase
of marketable securities available-for-sale
|
|
|
(17,260
|
)
|
|
|
(25,256
|
)
|
Proceeds
from sale and maturity of marketable securities
available-for-sale
|
|
|
32,794
|
|
|
|
42,046
|
|
Payments
related to sale of Preclinical Division
|
|
|
(1,843
|
)
|
|
|
-
|
|
Net
investing activities of discontinued operations
|
|
|
-
|
|
|
|
(371
|
)
|
Net
cash flows from investing activities
|
|
|
11,953
|
|
|
|
11,096
|
|
Cash
flows from financing activities:
|
|
|
|
|
|
|
|
|
Proceeds
from issuance of common stock to employees
|
|
|
10
|
|
|
|
145
|
|
Repayments
of an equipment loan
|
|
|
(36
|
)
|
|
|
(35
|
)
|
Net
financing activities of discontinued operations
|
|
|
-
|
|
|
|
(107
|
)
|
Net
cash flows from financing activities
|
|
|
(26
|
)
|
|
|
3
|
|
Net
(decrease) in cash and cash equivalents
|
|
|
(3,060
|
)
|
|
|
(19,831
|
)
|
Cash
and cash equivalents, beginning of period
|
|
|
25,700
|
|
|
|
43,946
|
|
Cash
and cash equivalents, end of period
|
|
$
|
22,640
|
|
|
$
|
24,115
|
|
Supplemental
disclosure:
|
|
|
|
|
|
|
|
|
Interest
paid
|
|
$
|
4
|
|
|
$
|
16
|
|
See
accompanying notes.
GENE
LOGIC INC.
September
30, 2007
(in
thousands, except share and per share data)
(Unaudited)
Note
1 — Organization and summary of significant accounting
policies
Description
of Business
Gene
Logic
Inc., including its wholly owned subsidiaries, Gene Logic Ltd. (United Kingdom
subsidiary) and Gene Logic K.K. (Japan subsidiary), (collectively “Gene Logic”
or the “Company”), employs integrative pharmacology know how that enables the
Company to determine new development paths for drug candidates provided by
its
partners and for which development has been discontinued for reasons other
than
safety. “Integrative pharmacology” is the study of the changes
produced in living animals by chemical substances, especially drugs, applied
on
a whole-animal or organ systems-level basis. The Company also seeks
to obtain drug candidates and/or rights to such candidates that it expects
to
reposition and, after possible further development by the Company, license
to
third parties for the benefit of its own proprietary portfolio.
The
Company has also developed and commercialized proprietary genomic and
toxicogenomic databases, toxicogenomic services, software tools and data
generation and analysis and other related services that enable customers
worldwide to discover and prioritize drug targets, identify biomarkers, predict
toxicity and understand mechanisms of toxicity and understand mechanisms of
action of specific compounds. In addition, the Company has begun to
utilize its Genomics assets to research and develop molecular diagnostics for
human health care.
In
2006,
the Company’s services were organized into three business segments: genomics and
toxicogenomics services (“Genomics Division”), preclinical contract research
services (“Preclinical Division”) and drug repositioning services (“Drug
Repositioning and Development Division”). On December 15, 2006, the
Company sold its Preclinical Division, which has now been classified as a
discontinued operation (see Note 4).
The
Drug
Repositioning and Development Division is engaged in the business of research
and development of drug candidates owned by its partners or by the
Company. The Company applies its proprietary integrative pharmacology
program for the purpose of determining new potential therapeutic indications
for
compounds that have failed clinical studies for reasons other than
safety.
The
Genomics Division licenses proprietary genomics and toxicogenomics databases
and
software tools and provides toxicogenomics services, microarray data generation
and analysis services and other related services. In 2006, in
response to an unexpected decline in demand for database subscriptions, the
Company reduced the staff and operational costs of its Genomics
Division. Following consideration of various strategic alternatives
for its Genomics Division, the Company signed an agreement in October 2007
to
sell certain assets (“Genomics Assets”) related to the business of its Genomics
Division, subject to the approval by the Company’s stockholders (see Note
2). The Company will retain full rights in perpetuity to utilize the
genomics databases for its Drug Repositioning and Development
Division. In addition, the Company will also retain those assets
(“Molecular Diagnostics Assets”) of the Genomics Division related to molecular
diagnostics and continues to explore strategic alternatives for these
assets. The Company has reduced expenses for its Genomics Division
while continuing to serve new and existing Genomics customers.
Basis
of Presentation
The
accompanying unaudited consolidated condensed financial statements have been
prepared in accordance with United States Generally Accepted Accounting
Principles (“GAAP”) for interim financial information and the instructions to
Form 10-Q and Article 10 of Regulation S-X. The consolidated
condensed balance sheet as of September 30, 2007, consolidated condensed
statements of operations for the three and nine months ended September 30,
2007
and 2006 and the consolidated condensed statements of cash flows for the nine
months ended September 30, 2007 and 2006 are unaudited, but include all
adjustments (consisting of normal recurring adjustments) that the Company
considers necessary for a fair presentation of the financial position, operating
results and cash flows, respectively, for the periods
presented. Although the Company believes that the disclosures in
these financial statements are adequate to make the information presented not
misleading, certain information and footnote information normally included
in
financial statements prepared in accordance with GAAP have been condensed or
omitted pursuant to the rules and regulations of the United States Securities
and Exchange Commission (“SEC”). All material intercompany accounts
and transactions have been eliminated in consolidation.
As
a
result of the Company’s sale of its Preclinical Division on December 15, 2006
and in accordance with Statement of Financial Accounting Standards No. 144,
“Accounting for the Impairment or Disposal of Long-Lived Assets”, for 2006 the
Company has classified the results of operations of the Preclinical Division
as
a discontinued operation. The results of operations for the Genomics
Division (not including the business associated with the Molecular Diagnostics
Assets) will not be classified as a discontinued operation until the requisite
stockholder approval has been obtained (see Note 2).
Results
for any interim period are not necessarily indicative of results for any future
interim period or for the entire year. The accompanying unaudited
consolidated condensed financial statements should be read in conjunction with
the consolidated financial statements and notes thereto included in the
Company’s Annual Report on Form 10-K for the year ended December 31,
2006.
Use
of
Estimates
The
preparation of financial statements in conformity with GAAP requires management
to make estimates and assumptions that affect the reported amounts of assets
and
liabilities and disclosure of contingent assets and liabilities at the date
of
the financial statements and the reported amounts of revenue and expenses during
the reporting period. Actual results could differ from those
estimates.
Inventory
Inventory
is stated at the lower of cost or market. Cost for microarrays and
laboratory reagents is determined using the first-in, first-out method and
cost
for tissue samples is determined using the average cost method. All
inventory is reviewed for impairment and appropriate reserves are
recorded. All inventory is classified as raw
materials. The following table sets forth information on the
composition of the Company’s inventory as of the indicated periods:
|
|
September
30,
|
|
|
December
31,
|
|
|
|
2007
|
|
|
2006
|
|
Microarrays
|
|
$
|
946
|
|
|
$
|
2,233
|
|
Laboratory
reagents
|
|
|
210
|
|
|
|
510
|
|
Tissue
samples
|
|
|
-
|
|
|
|
1,788
|
|
|
|
|
1,156
|
|
|
|
4,531
|
|
Less:
|
|
|
|
|
|
|
|
|
Microarray
reserves
|
|
|
-
|
|
|
|
(647
|
)
|
Tissue
sample reserves
|
|
|
-
|
|
|
|
(1,704
|
)
|
Inventory,
net
|
|
$
|
1,156
|
|
|
$
|
2,180
|
|
Comprehensive
Loss
The
Company accounts for comprehensive loss as prescribed by Statement of Financial
Accounting Standards (‘SFAS’) No. 130, “Reporting Comprehensive
Income”. Comprehensive income (loss) is the total net income (loss)
plus all changes in equity during the period except those changes resulting
from
investment by and distribution to owners. Total comprehensive loss
was $7,898 and $26,573 for the three months ended September 30, 2007 and 2006,
respectively, and $25,844 and $49,757 for the nine months ended September 30,
2007 and 2006, respectively.
New
Accounting Pronouncements
In
September 2006, the Financial Accounting Standards Board (“FASB”) issued SFAS
No. 157, “Fair Value Measurements” (“SFAS 157”). SFAS 157 defines
fair value, establishes a framework for measuring fair value under generally
accepted accounting principles and expands disclosures about fair value
measurements. SFAS 157 emphasizes that fair value is a market-based
measurement, not an entity-specific measurement, and states that a fair value
measurement should be determined based on the assumptions that market
participants would use in pricing the asset or liability. This
Statement applies under other accounting pronouncements that require or permit
fair value measurements, for which the FASB previously concluded in such
accounting pronouncements that fair value is the relevant measurement
attribute. Accordingly, this Statement does not require any new fair
value measurements. SFAS 157 is effective for fiscal years beginning
after November 15, 2007 and the Company intends to adopt it on January 1,
2008. The Company is currently evaluating the impact, if any, that
SFAS 157 will have on its financial position, results of operations and cash
flows, but does not believe the effect will be material.
In
June
2006, the FASB issued Interpretation No. 48, “Accounting for Uncertainty in
Income Taxes” (“FIN 48”). FIN 48 clarifies the accounting for
uncertainty in income taxes in an enterprise’s financial statements in
accordance with SFAS No. 109, “Accounting for Income Taxes”. FIN 48
prescribes a minimum recognition threshold and measurement attribute for
financial statement recognition and measurement of a tax position. If
a tax position does not meet the more-likely-than-not initial recognition
threshold, the benefit would not be recorded in the financial
statements. The Company adopted FIN 48 on January 1, 2007; the
adoption did not have a material effect on the Company.
If
applicable, the Company would recognize interest and penalties related to income
tax matters in income tax expense. No interest and penalties were
recognized in the Consolidated Condensed Statements of Operations for the three
and nine months ended September 30, 2007 and the Consolidated Condensed Balance
Sheet at September 30, 2007. The Company and its subsidiaries file
consolidated and separate income tax returns in the United States and in a
number of state and foreign jurisdictions. The Company is subject to
tax examinations in its major tax jurisdictions for all years since
inception.
Note
2 — Proposed sale of Genomics Assets
On
October
15, 2007, the Company announced that it had signed an agreement to sell to
Ocimum Biosolutions, Inc., Ocimum Biosolutions, LTD or its affiliate
(collectively “Ocimum”) the Genomics Assets for $10,000 ($7,000 in cash and a
$3,000 promissory note due 18 months from the date of closing) and the
assumption, by Ocimum, of certain liabilities and ongoing contractual
obligations. The Company has incurred costs to sell its Genomics
Assets through September 30, 2007 in the amount of $981 and anticipates it
will
incur additional costs of approximately $400 in connection with the
sale. The sales price is subject to adjustment based on certain
potential revisions to the carrying value of assets and liabilities at the
date
of closing. Consummation of the sale is subject to the approval by
the Company’s stockholders. The Company also is seeking stockholder
approval for a sale of the assets of the Genomics Division in the event that
the
agreement with Ocimum is terminated.
As
a
result of the proposed sale of its Genomics Assets, the Company expects to
record a loss of approximately $3,500, excluding previously recorded selling
costs, reflecting the sale price, including estimates for the assumption of
certain liabilities and ongoing contractual obligations by Ocimum, less the
carrying value of the assets and selling costs as of closing. The
loss is expected to be recorded in the fourth quarter of 2007. The
Company will continue to evaluate the sale price, carrying value of the assets
and certain liabilities and estimated selling costs. Any subsequent
change to these values could result in a change to the expected
loss. The value of the Molecular Diagnostic Assets is not included in
the determination of the loss from the sale of its Genomics
Assets. The sale of the Genomics Assets to Ocimum is subject to
certain conditions, including the approval by the Company’s stockholders and the
absence of certain material adverse changes in the Company. In
addition, the agreement with Ocimum may be terminated under certain conditions,
including by the Company in the event of a superior offer. There is
no assurance that the sale to Ocimum will be consummated.
In
conjunction with the proposed sale of its Genomics Assets, the Company is
seeking stockholder approval to change its name to Ore Pharmaceuticals
Inc.
Note
3 — Stock-based compensation
At
September 30, 2007, the Company has the following stock-based compensation
plans: 1997 Equity Incentive Plan (the “Stock Plan”) and 1997 Non-Employee
Directors’ Stock Option Plan (the “Directors’ Plan”). The Company may
grant both stock option and restricted stock awards under the Stock Plan and
stock option awards under the Directors’ Plan. The termination of the
Employee Stock Purchase Plan was approved by the Company’s Board of Directors in
June 2007.
Effective
January 1, 2006, the Company adopted the fair value recognition provisions
of
Statement of Financial Accounting Standards No. 123(R) (revised 2004),
“Share-Based Payment,” using the modified prospective transition method and
therefore did not restate results for prior periods. For the three
and nine months ended September 30, 2007, the Company recorded stock-based
compensation expense of $235 and $573, respectively. The impact on
basic and diluted net loss per share for the three and nine months ended
September 30, 2007 was $0.01 and $0.02, respectively. For the three
and nine months ended September 30, 2006, the Company recorded stock-based
compensation expense of $139 and $689, respectively. The impact on
basic and diluted net loss per share for the three and nine months ended
September 30, 2006 was $0.00 and $0.02, respectively.
Stock
Option Awards
The
Company determined the fair value of each option grant on the date of grant
using the Black-Scholes option pricing model for the indicated periods, with
the
following assumptions:
|
|
|
Three
Months Ended
|
|
|
Nine
Months Ended
|
|
|
|
|
September
30,
|
|
|
September
30,
|
|
|
|
|
2007
|
|
|
2006
(1)
|
|
|
2007
|
|
|
2006
|
|
|
Weighted
average fair value of grants
|
|
|
$0.59
|
|
|
|
–
|
|
|
|
$0.75
|
|
|
|
$1.11
|
|
|
Expected
volatility
|
|
|
59%
|
|
|
|
–
|
|
|
|
58%
|
|
|
|
53%
|
|
|
Risk-free
interest rate
|
|
|
4.47%
|
|
|
|
–
|
|
|
4.47%
to 4.51%
|
|
|
4.49%
to 5.11%
|
|
|
Expected
lives
|
|
3
years
|
|
|
|
–
|
|
|
3
years
|
|
|
3
years
|
|
|
Dividend
rate
|
|
|
0%
|
|
|
|
–
|
|
|
|
0%
|
|
|
|
0%
|
|
(1)
No
stock options awards were granted during the three months ended September 30,
2006.
The
following is a summary of option activity for the nine months ended September
30, 2007:
|
|
|
|
|
|
Per
Share
|
|
|
|
|
|
|
|
Weighted-
|
|
|
|
|
Number
of
|
|
|
Average
|
|
|
|
|
Shares
|
|
|
Exercise
Price
|
|
|
Outstanding
at January 1, 2007
|
|
|
4,528,956
|
|
|
$
|
6.88
|
|
|
Options
granted
|
|
|
1,603,200
|
|
|
$
|
1.96
|
|
|
Options
exercised
|
|
|
(34,210
|
)
|
|
$
|
0.30
|
|
|
Options
cancelled
|
|
|
(1,543,178
|
)
|
|
$
|
5.21
|
|
|
Outstanding
at September 30, 2007
|
|
|
4,554,768
|
|
|
$
|
5.76
|
|
|
|
|
|
|
|
|
|
|
|
|
Exercisable
at September 30, 2007
|
|
|
3,226,411
|
|
|
$
|
7.30
|
|
The
total
intrinsic value (the difference between the Company’s closing stock price on the
last trading day of the third quarter of 2007 and the exercise price, multiplied
by the number of in-the-money options) that would have been received by the
option holders had all option holders exercised their options on September
30,
2007 was zero. This amount is subject to change based on changes to
the fair market value of the Company’s Common Stock.
Of
the
stock options outstanding at September 30, 2007, 584,332 are stock options
held
by employees of the Genomics Division that will be subject to cancellation
in
most cases, within three months after the sale of the Genomics Assets, unless
exercised prior to such cancellation, in accordance with the terms of the Stock
Plan and stock option award upon the closing of the sale of the Genomics
Assets.
Restricted
Stock Awards
During
the
nine months ended September 30, 2007, the Committee approved grants for shares
of restricted stock under the Stock Plan subject to certain performance-based
vesting conditions which, if not met, would result in forfeiture of the shares
and reversal of any previously recognized related stock-based compensation
expense.
The
following is a summary of restricted stock awards activity for the nine months
ended September 30, 2007:
|
|
|
|
|
|
Per
Share
|
|
|
|
|
|
|
|
Weighted-
|
|
|
|
|
|
|
|
Average
|
|
|
|
|
Number
of
|
|
|
Grant-Date
|
|
|
|
|
Shares
|
|
|
Fair
Value
|
|
|
Outstanding
at January 1, 2007
|
|
|
-
|
|
|
$
|
-
|
|
|
Restricted
stock granted
|
|
|
410,003
|
|
|
$
|
1.62
|
|
|
Restricted
stock vested
|
|
|
(40,000
|
)
|
|
$
|
1.91
|
|
|
Restricted
stock forfeited
|
|
|
(91,898
|
)
|
|
$
|
1.91
|
|
|
Outstanding
at September 30, 2007
|
|
|
278,105
|
|
|
$
|
1.48
|
|
Performance-based
nonvested share awards are recognized as compensation expense over the expected
vesting period based on the fair value at the date of grant and the number
of
shares ultimately expected to vest. The shares of restricted stock
outstanding at September 30, 2007 will only vest if certain performance
milestones are achieved, which the Company believes is probable.
Of
the
shares of restricted stock outstanding at September 30, 2007, 40,484 shares
will
vest in accordance with the terms of the restricted stock award upon the closing
of the sale of the Genomics Assets.
As
of
September 30, 2007, $867 of total unrecognized compensation cost related to
stock option and restricted stock awards is expected to be recognized over
a
weighted-average period of 1.7 years. This estimate does not include
the impact of other possible stock-based awards that may be made during future
periods.
Note
4 — Discontinued operation
As
previously discussed in Note 1, in 2006 the Company changed its strategic focus
and sold its Preclinical Divison for a sale price consisting of (A) $13,500
paid
at closing less transaction costs of $1,383 and (B) $1,500 held in escrow for
12
months to satisfy potential indemnification obligations under the
agreement. In addition, payment and performance under two leases held
by Gene Logic Laboratories, Inc. continue to be guaranteed by the Company,
pending the consent of each landlord to and the completion of the assignment
and
assumption of those guarantees by Bridge. If the guarantees are not
assumed by Bridge, Bridge will indemnify the Company with respect to any claims
against such guarantees.
As
a result of the Company’s sale of its
Preclinical Division on December 15, 2006, the operations of the Preclinical
Division have been classified as a discontinued operation. Summarized operating
results from the discontinued operation included in the Company’s Consolidated
Condensed Statements of Operations for the three and nine months ended September
30, 2006 are as follows
:
|
|
Three
Months Ended
|
|
|
Nine
Months Ended
|
|
|
|
September
30,
|
|
|
September
30,
|
|
|
|
2006
(1)
|
|
|
2006
(1)
|
|
|
|
|
|
|
|
|
Revenue
from discontinued operation
|
|
$
|
8,075
|
|
|
$
|
18,708
|
|
Loss
from discontinued operation
|
|
$
|
(11,811
|
)
|
|
$
|
(17,307
|
)
|
(1)
Includes $11,000 impairment charge during the three and nine months
ended
September 30, 2006.
|
|
Note
5 — Restructuring expenses
During
2006, the Company initiated a restructuring of its Genomics Division, which
it
has substantially completed. The Genomics Division restructuring included the
termination of 70 employees (none of whom were still employed by the Company
as
of December 31, 2006), the acceleration of future costs for certain laboratory
and office facilities that were no longer needed and the impairment of certain
intangible assets which the Company determined would no longer be utilized
by
the Genomics Division. The major components of the Genomics Division
restructuring liability as of September 30, 2007 and activity since January
1,
2007 are comprised of:
|
|
Accrual
Balance
as of
December
31,
2006
|
|
|
2007
Charges
Utilized
|
|
|
Accrual
Balance
as of
September
30,
2007
|
|
Severance
and related benefits
|
|
$
|
122
|
|
|
$
|
(122
|
)
|
|
$
|
-
|
|
Lease
obligations
|
|
|
1,819
|
|
|
|
(1,510
|
)
|
|
|
309
|
|
Total
|
|
$
|
1,941
|
|
|
$
|
(1,632
|
)
|
|
$
|
309
|
|
Note
6 — Segment information
In
2006,
the Company managed its business as three business segments: Genomics Division,
Preclinical Division and Drug Repositioning and Development
Division. On December 15, 2006, the Company sold its Preclinical
Division, which for 2006 has been classified as a discontinued operation (see
Note 4).
The
following table presents revenue and operating loss for the Genomics Division
and Drug Repositioning and Development Division segments, which comprise the
Company’s continuing operations for the indicated periods. Management
uses these measures to evaluate segment performance. To arrive at
operating income (loss) for each segment, management has included all direct
costs for providing the segment’s services and an allocation for corporate
overhead on a consistent and reasonable basis. Management has
excluded interest (income) expense, other (income) expense and
write-downs. Operating income (loss) could also exclude certain
unusual or corporate-related costs in the future.
The
following table sets forth information on reportable segments for the indicated
periods:
|
|
Three
Months Ended
|
|
|
Nine
Months Ended
|
|
|
|
September
30,
|
|
|
September
30,
|
|
|
|
2007
|
|
|
2006
|
|
|
2007
|
|
|
2006
|
|
Genomics
Services
|
|
|
|
|
|
|
|
|
|
|
|
|
Revenue
|
|
$
|
3,684
|
|
|
$
|
3,698
|
|
|
$
|
12,356
|
|
|
$
|
17,129
|
|
Operating
loss
|
|
|
(4,850
|
)
|
|
|
(11,832
|
)
|
|
|
(14,781
|
)
|
|
|
(23,042
|
)
|
Depreciation
and amortization expense
|
|
|
1,876
|
|
|
|
2,304
|
|
|
|
6,118
|
|
|
|
7,333
|
|
Drug
Repositioning and Development Services
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Revenue
|
|
$
|
841
|
|
|
$
|
6
|
|
|
$
|
879
|
|
|
$
|
36
|
|
Operating
loss
|
|
|
(3,487
|
)
|
|
|
(3,711
|
)
|
|
|
(12,652
|
)
|
|
|
(11,241
|
)
|
Depreciation
and amortization expense
|
|
|
278
|
|
|
|
248
|
|
|
|
823
|
|
|
|
799
|
|
A
reconciliation of segment operating loss to loss from continuing operations
for
the indicated periods is as follows:
|
|
Three
Months Ended
|
|
|
Nine
Months Ended
|
|
|
|
September
30,
|
|
|
September
30,
|
|
|
|
2007
|
|
|
2006
|
|
|
2007
|
|
|
2006
|
|
Segment
Operating Loss
|
|
|
|
|
|
|
|
|
|
|
|
|
Genomics
services
|
|
$
|
(4,850
|
)
|
|
$
|
(11,832
|
)
|
|
$
|
(14,781
|
)
|
|
$
|
(23,042
|
)
|
Drug
repositioning and development services
|
|
|
(3,487
|
)
|
|
|
(3,711
|
)
|
|
|
(12,652
|
)
|
|
|
(11,241
|
)
|
|
|
|
(8,337
|
)
|
|
|
(15,543
|
)
|
|
|
(27,433
|
)
|
|
|
(34,283
|
)
|
Interest
(income), net
|
|
|
(463
|
)
|
|
|
(633
|
)
|
|
|
(1,594
|
)
|
|
|
(2,162
|
)
|
Other
(income) expense
|
|
|
32
|
|
|
|
(66
|
)
|
|
|
46
|
|
|
|
35
|
|
Write-down
of equity investment
|
|
|
-
|
|
|
|
-
|
|
|
|
-
|
|
|
|
275
|
|
Loss
from continuing operations
|
|
$
|
(7,906
|
)
|
|
$
|
(14,844
|
)
|
|
$
|
(25,885
|
)
|
|
$
|
(32,431
|
)
|
During
the
three months ended September 30, 2007, four customers accounted for 58% of
the
Company’s revenue (Customer A-17%, Customer B-15%, Customer C-14% and Customer
D-12%). During the nine months ended September 30, 2007, three
customers each accounted for 52% of the Company’s revenue (Customer C-22%,
Customer B-16% and Customer D-14%). During the three months ended
September 30, 2006, three customers accounted for 56% of the Company’s revenue
(Customer E-20%, Customer B-20% and Customer D-16%). During the nine
months ended September 30, 2006, four customers each accounted for 50% of the
Company’s revenue (Customer F-14%, Customer E-13%, Customer B-13% and Customer
D-10%). Customer A is a Drug Repositioning and Development Division
customer while Customers B, C, D, E and F are Genomics Division
customers.
The
following table sets forth information on the composition of the Company’s total
revenue from continuing operations by geographic region:
|
|
Geographic
Region
|
|
|
|
North
America
|
|
|
Europe
|
|
|
Pacific
Rim
|
|
For
the three months ended:
|
|
|
|
|
|
|
|
|
|
September
30, 2007
|
|
|
46%
|
|
|
|
39%
|
|
|
|
15%
|
|
September
30, 2006
|
|
|
35%
|
|
|
|
24%
|
|
|
|
41%
|
|
For
the nine months ended:
|
|
|
|
|
|
|
|
|
|
|
|
|
September
30, 2007
|
|
|
56%
|
|
|
|
26%
|
|
|
|
18%
|
|
September
30, 2006
|
|
|
49%
|
|
|
|
22%
|
|
|
|
29%
|
|
This
Quarterly Report on Form 10-Q (“Form 10-Q”) contains forward-looking statements
regarding future events and the future results of Gene Logic Inc. (“Gene Logic”)
that are based on current expectations, estimates, forecasts and projections
about the industries in which Gene Logic operates and the beliefs and
assumptions of the management of Gene Logic. Words such as “expects,”
“anticipates,” “targets,” “goals,” “projects,” “intends,” “plans,” “believes,”
“seeks,” “estimates,” variations of such words, and similar expressions are
intended to identify such forward-looking statements. These
forward-looking statements are only predictions and are subject to risks,
uncertainties and assumptions. Therefore, actual results may differ
materially and adversely from those expressed in any forward-looking statements.
Factors that might cause or contribute to such differences include those
discussed in the Company’s Annual Report on Form 10-K for the year ended
December 31, 2006 under the section entitled “Risk Factors” and in our
subsequent filings with the Securities and Exchange Commission. Gene
Logic undertakes no obligation to revise or update publicly any forward-looking
statements to reflect any change in management’s expectations with regard
thereto or any change in events, conditions, or circumstances on which any
such
statements are based.
Unless
the
context otherwise requires, references in this Form 10-Q to “Gene Logic,” “Gene
Logic Laboratories Inc.,” “Gene Logic Ltd.,” “Gene Logic K.K.,” the “Company,”
“we,” “us,” and “our” refer to Gene Logic Inc. and its wholly owned
subsidiaries. Gene Logic®, BioExpress® and ToxExpress® are registered trademarks
of Gene Logic.
OVERVIEW
We
currently conduct our operations through two business segments (we have entered
into an agreement to sell our Genomics Assets as discussed further
below):
·
|
Drug
Repositioning and Development Division:
We obtain drug compounds
from our pharmaceutical company partners or from other sources that
have
already been assessed as safe in human clinical trials, but have
been
discontinued by their sponsors for reasons other than
safety. We apply our proprietary integrative pharmacology
program, consisting of biological screening technologies, genomics
databases and bioinformatics software, to determine new potential
therapeutic indications for these clinical stage compounds to enable
our
partners to return such compounds to clinical
development. Under our partnership agreements, we expect to
share in our partners’ successful development and commercialization of
these repositioned drug compounds through both milestone payments
during
development and royalties from sales. In most cases, if our
partner decides not to re-enter a drug candidate into its own development
pipeline, we are entitled to obtain the development rights to the
compound. Using compounds that we obtain either through our
partner's decision to not pursue further development or from other
sources, we also expect to use our integrative pharmacology program
to
reposition and possibly further develop compounds for our own account
and
to establish out-licensing arrangements to complete development and
commercialization of these
compounds.
|
·
|
Genomics
Division:
Since 1996, we have been primarily devoted to
developing and commercializing proprietary genomic and toxicogenomic
databases, toxicogenomic services, software tools and data generation
and
analysis and other related services. The Genomics services we
provide enable customers worldwide to discover and prioritize drug
targets, identify biomarkers, predict toxicity and understand mechanisms
of toxicity and action of specific compounds. In October 2007,
we signed an agreement to sell certain assets (“Genomics Assets”) related
to the business of our Genomics Division, subject to approval by
the
Company’s stockholders; however, we will retain those assets (“Molecular
Diagnostic Assets”) of the Genomics Division related to molecular
diagnostics and continue to explore strategic alternatives for these
assets.
|
In
2004,
Gene Logic created a pharmaceutical development division (known as our Drug
Repositioning and Development Division) within the Company to identify and
develop new or expanded uses for small molecule therapeutics. Based
on advances in our Drug Repositioning and Development Division and changes
in
our Genomics business, and after concluding a comprehensive review of our
strategy, we have decided to focus our resources on becoming a pharmaceutical
development company. We are now building a pipeline of potential drug
candidates by applying our proprietary integrative pharmacology program to
find
new and expanded uses for such drug candidates.
In
2005
and 2006, we entered into drug development partnerships with Pfizer, Inc.,
F.
Hoffmann-La Roche Ltd, Eli Lilly and Company and NV Organon. In 2007,
we entered into new drug development partnerships with Abbott Laboratories,
H.
Lundbeck A/S, Merck Serono and Solvay Pharmaceuticals B.V. Based upon
our experience to date in evaluating more than 100 compounds, we have succeeded
in determining new hypotheses at the rate of approximately one hypothesis for
every three compounds evaluated. Several of these compounds are
currently in the process of animal model validation. We anticipate
that some of these compounds may re-enter development at some point in 2008,
either under the sponsorship of our partner or under our own
sponsorship.
In
2006,
in response to an unexpected decline in demand for database subscriptions,
we
reduced the staff and operational costs of our Genomics
Division. Following consideration of various strategic alternatives
for our Genomics Division, we signed an agreement in October 2007 to sell our
Genomics Assets to Ocimum Biosolutions Inc., Ocimum Biosolutions, LTD or its
affiliate (collectively “Ocimum”) for $10 million ($7 million in cash and a $3
million promissory note due 18 months from the date of closing) and the
assumption, by Ocimum, of certain liabilities and ongoing contractual
obligations. We have incurred costs to sell our Genomics Assets
through September 30, 2007 in the amount of $1.0 million and we anticipate
we
will incur additional costs of approximately $0.4 million in connection with
the
sale. Under the terms of the agreement, we will retain the exclusive,
perpetual right to use our genomics databases for drug repositioning and
development on behalf of our pharmaceutical company partners and in our own
drug
development programs. We also retain the Molecular Diagnostics Assets
and continue to explore strategic alternatives for these assets.
As
a
result of the sale of our Genomics Assets, we expect to record a loss of
approximately $3.5 million, excluding previously recorded selling costs,
reflecting the sale price, including estimates for the assumption of certain
liabilities and ongoing contractual obligations by Ocimum, less the carrying
value of the assets and selling costs as of closing. The loss is
expected to be recorded in the fourth quarter of 2007. We will
continue to evaluate the sale price, carrying value of the assets and certain
liabilities and estimated selling costs. Any subsequent change to
these values could result in a change to the expected loss. The value
of our Molecular Diagnostics Assets is not included in the determination of
the
loss from the sale of our Genomics Assets. The sale of our Genomics
Assets to Ocimum is subject to certain conditions, including the approval by
the
Company’s stockholders and the absence of certain material adverse changes in
the Company. In addition, the agreement with Ocimum may be terminated
under certain conditions, including by us in the event of a superior
offer. There is no assurance that the sale to Ocimum will be
consummated. We are also seeking stockholder approval for a sale of
the assets of the Genomics Division in the event that the agreement with Ocimum
is terminated.
In
2006,
we sold Gene Logic Laboratories Inc. to Bridge Pharmaceuticals, Inc. (“Bridge”)
for (A) $13.5 million paid at closing less transaction costs of $1.4 million
and
(B) $1.5 million held in escrow for 12 months to satisfy potential
indemnification obligations under the agreement. In addition, payment
and performance under two leases held by Gene Logic Laboratories, Inc. continue
to be guaranteed by us, pending the consent of each landlord to and the
completion of the assignment and assumption of those guarantees by
Bridge. If the guarantees are not assumed by Bridge, Bridge will
indemnify us with respect to any claims against such guarantees.
Currently,
the majority of our revenue comes from our Genomics
Division. Historically, we have derived a majority of our Genomics
Division revenue from licenses to our databases in the form of multi-year
subscriptions and annual subscriptions to our smaller databases or a subset
of
our larger databases. We have also granted perpetual licenses to our
data and/or software tools. We also generate revenue from providing
other services, including microarray data generation and analysis services,
various toxicogenomics reports and other related services. Fees for
subscriptions to our databases are payable ratably over the life of the
agreement for multi-year agreements and ratably or up-front for shorter-term
agreements. In the case of perpetual licenses and data generation and
analysis and other services, fees are payable upon delivery of the data,
software or service. Generally, our Genomics Division contracts may
be terminated in the event of breach by either party that is not cured within
the applicable cure period.
Our
drug
repositioning and development agreements vary somewhat as to specific terms,
but
generally consist of the following:
·
|
We
agree with a partner on a group of drug candidates to be
evaluated. Our partner provides samples of the candidate and,
at our expense, we analyze each candidate using our integrative
pharmacology program;
|
·
|
As
to drug candidates for which we have identified new uses and that
our
partners take back into development, we are entitled to receive
success-based payments when certain milestones are
achieved. The totals range from $60-100+ million per compound
and in most cases include the following individual
milestones:
|
o
|
Notice
of re-initiation of development,
|
o
|
Filing
of an Investigational New Drug (“IND”) with the
FDA,
|
o
|
Establishment
of proof of concept in a Phase II clinical
trial,
|
o
|
Commencement
of a Phase III clinical trial, and
|
o
|
Receipt
of market approval in the United States, in Europe, or in Japan;
and
|
·
|
As
to drug candidates returned by our partners to commercial development,
we
are entitled to receive royalty payments, as a percentage of sales,
that
range from single- to low double-digits and are generally tiered
according
to sales volume.
|
Our
agreement with NV Organon involves co-ownership and co-development of
repositioned drug candidates, and it therefore differs substantially from our
other agreements.
In
most
cases, if our partner decides not to take the drug candidate back into
development, we have development rights that, if we elect to exercise them,
would entitle our partner to receive milestone payments and royalties on
sales. We may choose to license such candidates to a third party for
development, or we may invest in further development to increase a particular
candidate’s value prior to out-licensing.
We
acquired our first proprietary drug candidate, GL1001, from
Millennium. Through the application of our integrative pharmacology
program, we have determined a new therapeutic hypothesis, inflammatory bowel
disease, for this compound. This is not the indication for which this
compound was originally intended. Using an
in vivo
model, we
have now validated our hypothesis to treat inflammatory bowel
disease. We are continuing to invest in further development of this
compound as we seek to secure a partner to facilitate its advanced stages of
development.
We
may
also obtain drug candidates from third parties, such as those we obtain from
our
partners. In this repositioning scenario, we may choose either to
out-license without further development, or we may invest in further development
prior to out-licensing.
From
time
to time, we may license certain of our non-core technologies to third parties,
as most recently evidenced by our licensing of certain technology rights to
Lundbeck.
We
have
incurred net losses in each year since our inception, including losses of $54.7
million in 2006, $48.3 million in 2005 and $28.5 million in 2004. At
September 30, 2007, we had an accumulated deficit of $341.6
million. Our losses have resulted principally from costs incurred in
the development, marketing and sale of services from our Genomics and
Preclinical Divisions, development of the Drug Repositioning and Development
Division, the impairment of our Preclinical Division goodwill and acquisitions
of research and development. These costs have exceeded our revenue
and we expect to incur additional losses in the future.
RESULTS
OF CONTINUING OPERATIONS
Three
Months Ended September 30, 2007 and 2006
Revenue.
We derive most of our revenue from our Genomics Division
services. Revenue increased $0.8 million, or 22%, to $4.5 million for
the three months ended September 30, 2007 from $3.7 million for the same period
in 2006. This increase was largely due to the revenue recorded by the
Drug Repositioning and Development Division as a result of an agreement signed
at the end of the second quarter of 2007 with Lundbeck for licensing of certain
technology rights unrelated to its drug repositioning partnership. During three
months ended September 30, 2007, four customers accounted for 58% of our total
revenue. During the three months ended September 30, 2006, three
customers accounted for 56% of our total revenue.
Compared
to the same period in 2006, we expect revenue for the fourth quarter of 2007
to
decrease significantly due in part to customer uncertainty concerning our
decision to sell our Genomics Assets.
Database
Production Expense.
Database production expenses, which consist
primarily of costs to provide microarray data generation and analysis services
and costs related to the acquisition and processing of tissues and overhead
expenses needed to generate the content for the BioExpress and ToxExpress System
databases, decreased to $5.1 million for the three months ended September 30,
2007 from $6.0 million for the same period in 2006. The decrease
reflects the favorable impact of the restructuring of the Genomics Division
with
reductions in employee and facilities costs of $0.9 million and a decrease
of
$0.4 million in depreciation and amortization expense, partially offset by
an
increase in amounts spent on adding new Genomics database content of $0.6
million. For the remainder of 2007, we expect database production
expenses to continue to decrease primarily due to lower employee and facility
costs as a result of the Genomics Division restructuring.
Research
and Development Expense.
Research and development expenses, which
consist primarily of costs associated with the evaluation of customer-supplied
drug candidates and, to a lesser degree, further development of our proprietary
drug candidate, GL1001
,
increased slightly to $2.7 million for
the three months ended September 30, 2007 from $2.6 million for the same period
in 2006. The increase primarily reflects increased expenses
associated with
in vivo
efficacy models to evaluate suitability of
certain drug candidates for re-entering clinical trials for their proposed
indications and further development of GL1001, partially offset by $0.5 million
in lower spending due to the virtual elimination of research and development
related to the Genomics Division. For the remainder of 2007, we
expect research and development expenses to increase modestly, as we continue
to
evaluate drug candidates supplied by our drug discovery partners and we will
incur additional expenses because of our decision to pursue further development
of GL1001.
Selling,
General and Administrative Expense.
Selling, general and administrative
expenses, which consist primarily of sales, marketing, accounting, legal, human
resources and other general corporate expenses, decreased to $5.0 million for
three months ended September 30, 2007 from $5.2 million for the same period
in
2006.
The decrease is largely due to a reduction of $0.8
million in employee costs for our Genomics Division and Corporate staff plus
other cost savings, partially offset by increased expenses in 2007 of $0.5
million in costs associated with the sale of our Genomics Assets and $0.4
million in employee retention benefits meant to stabilize our workforce during
this time of transition.
For 2007, we expect selling,
general and administrative expenses to remain at the same level as in
2006.
Net
Interest Income.
Net interest income decreased slightly to $0.5 million
for the three months ended September 30, 2007 from $0.6 million for 2006, due
to
a decrease in the balance of our cash and cash equivalents and marketable
securities available-for-sale, partially offset by increases in our rates of
return on investments.
Nine
Months Ended September 30, 2007 and 2006
Revenue.
We derive most of our revenue from our Genomics Division
services. Revenue decreased $3.9 million, or 23%, to $13.2 million
for the nine months ended September 30, 2007 from $17.2 million for the same
period in 2006. The revenue decrease was caused primarily by our
customers’ having shifted their emphasis from research on early stage drug
development, for which many of our Genomics Division services are targeted,
into
later-stage development and validation efforts. The 2007 results
reflect the absence of $5.7 million in subscription fees from expired
agreements, partially offset from $0.8 million in revenue for the Drug
Repositioning and Development Division agreement with Lundbeck for licensing
of
certain technology rights unrelated to its drug repositioning partnership and
$0.7 million in fees for subscriptions from new and expanded arrangements with
our customers. During the nine months ended September 30, 2007, three customers
accounted for 52% of our total revenue. During the nine months ended
September 30, 2006, four customers accounted for 50% of our total
revenue.
Database
Production Expense.
Database production expenses, which consist
primarily of costs to provide microarray data generation and analysis services
and costs related to the acquisition and processing of tissues and overhead
expenses needed to generate the content for the BioExpress and ToxExpress System
databases, decreased to $15.8 million for the nine months ended September 30,
2007 from $21.5 million for the same period in 2006. The decrease
reflects the favorable impact of the restructuring of the Genomics Division
with
reductions in employee and facilities costs of $3.4 million and a decrease
of
$1.0
million in depreciation and amortization
expense.
Research
and Development Expense.
Research and development expenses, which
consist primarily of costs associated with the evaluation of customer-supplied
drug candidates and, to a lesser degree, further development of our proprietary
drug candidate, GL1001, increased slightly to $7.9 million for the nine months
ended September 30, 2007 from $7.6 million for the same period in
2006. The increase primarily reflects increased expenses associated
with
in vivo
efficacy models to evaluate suitability of certain drug
candidates for re-entering clinical trials for their proposed indications and
further development of GL1001, partially offset by $1.4 million in lower
spending due to the virtual elimination of research and development related
to
the Genomics Division.
Selling,
General and Administrative Expense.
Selling, general and administrative
expenses, which consist primarily of sales, marketing, accounting, legal, human
resources and other general corporate expenses, remained flat at $17.0 million
for nine months ended September 30, 2007 and 2006. The increase in
expenses of $1.4 million in employee retention benefits meant to stabilize
our
workforce during this time of transition, $1.0 million in costs associated
with
the Genomics sales process and $0.9 million in executive severance and retention
benefits were offset by
a reduction of $2.5 million in
employee costs for our Genomics Division and Corporate staff plus other costs
savings.
Net
Interest Income.
Net interest income decreased to $1.6 million for the
nine months ended September 30, 2007 from $2.2 million for 2006, due to a
decrease in the balance of our cash and cash equivalents and marketable
securities available-for-sale, partially offset by increases in our rates of
return on investments.
Write-down
of Equity Investment.
For the nine months ended September 30, 2006, in
connection with our investment in Xceed Molecular (“Xceed”, formerly MetriGenix
Corporation) we recorded a $0.3 million write-down of a warrant which was
terminated. At September 30, 2007, the book value of our investment
in Xceed was $3.0 million.
LIQUIDITY
AND CAPITAL RESOURCES
From
inception through September 30, 2007, we have financed our operations and
acquisitions through the issuance and sale of equity securities and payments
from customers. As of September 30, 2007, we had approximately $31.6
million in cash, cash equivalents and marketable securities available-for-sale,
compared to $50.1 million as of December 31, 2006.
Net
cash
from operating activities from continuing operations was negative $15.0 million
for the nine months ended September 30, 2007 compared to negative
$
29.3 million for the same period in 2006, primarily due to
the
timing of customer payments and payments in 2006 to Millennium and under our
compensation and retention plans. We presently anticipate that our
use of cash in the fourth quarter of 2007 will be lower than the third quarter
of 2007.
During
the
nine months ended September 30, 2007 and 2006, our investing activities
consisted primarily of purchases, sales and maturities of available-for-sale
securities, capital expenditures and payments related to the sale of our
Preclinical Division. Capital expenditures for the nine months ended
September 30, 2007 and 2006 were $0.5 million and $1.8 million,
respectively. The decrease in capital expenditures was primarily due
to the absence of 2006 equipment purchases used to expand our microarray data
generation and analysis capacity and capabilities.
For
the remainder of 2007, we expect the level of capital expenditures to be less
than $0.5 million.
On
December 15, 2006, we announced the closing of the sale of our Preclinical
Division to Bridge for a sale price consisting of (A) $13.5 million paid at
closing less transaction costs of $1.4 million and (B) $1.5 million held in
escrow for 12 months to satisfy potential indemnification obligations under
the
agreement. In January 2007, we repaid $1.2 million to Bridge in
conjunction with the final reconciliation of cash balances associated with
the
sale of our Preclinical Division. In July 2007, we paid $0.7 million
to Bridge for the final adjustment to the sale price.
In
October
2007, we signed an agreement to sell our Genomics Assets to Ocimum for $10
million ($7 million in cash and a $3 million promissory note due 18 months
from
the date of closing) and the assumption, by Ocimum, of certain liabilities
and
ongoing contractual obligations. The sale price is subject to
adjustment based on certain potential revisions to the carrying value of assets
and liabilities at the date of closing. Consummation of the sale is
subject to the approval by the Company’s stockholders. In connection
with the sale of our Genomics Assets, we expect to pay accrued employee
retention benefits of approximately $1.6 million
meant to
stabilize the Genomics Division employees during this transition and $1.1
million in associated transaction costs that are either accrued to date, but
not
yet paid or anticipated through closing.
Specific
future financial commitments from continuing operations as of September 30,
2007
are set forth in the following table:
|
|
|
|
|
Within
|
|
|
|
|
|
|
|
|
|
|
|
|
Total
|
|
|
3
Months
|
|
|
2008
& 2009
|
|
|
2010
& 2011
|
|
|
Beyond
2011
|
|
Long-term
debt
|
|
$
|
544
|
|
|
$
|
463
|
|
|
$
|
81
|
|
|
$
|
-
|
|
|
$
|
-
|
|
Operating
leases
|
|
|
4,982
|
|
|
|
465
|
|
|
|
2,804
|
|
|
|
1,428
|
|
|
|
285
|
|
Total
|
|
$
|
5,526
|
|
|
$
|
928
|
|
|
$
|
2,885
|
|
|
$
|
1,428
|
|
|
$
|
285
|
|
We
believe
that existing cash, cash equivalents and marketable securities
available-for-sale, anticipated payments from customers and net proceeds from
the proposed sale of the Genomics Assets will be sufficient to support our
operations for the foreseeable future. These estimates are
forward-looking statements that involve risks and uncertainties. Our
actual future capital requirements and the adequacy of our available funds
will
depend on many factors, including those discussed under “Risk Factors” in our
Annual Report on Form 10-K for the year ended December 31, 2006 and in our
subsequent filings with the Securities and Exchange Commission.
CRITICAL
ACCOUNTING POLICIES
Our
consolidated condensed financial statements are prepared in accordance with
accounting principles generally accepted in the United States, which require
management to make estimates and assumptions that affect the reported amounts
of
assets and liabilities at the date of the financial statements and the reported
amounts of revenue and expenses during the reporting period. Actual
results could differ from these estimates. The following discussion
highlights what we believe to be the critical accounting policies and judgments
made in the preparation of these consolidated condensed financial
statements.
REVENUE
RECOGNITION
Revenue
is
recognized in accordance with the SEC’s Staff Accounting Bulletin No. 104,
“Revenue Recognition” (“SAB 104”). SAB 104 requires that four basic
criteria be met before revenue can be recognized: 1) persuasive evidence of
an
arrangement exists; 2) delivery has occurred or services rendered; 3) the fee
is
fixed and determinable; and 4) collectability is reasonably
assured. As to 1), our business practices require that our services
be performed pursuant to contracts with our customers. As to 2), we
recognize revenue when services are rendered to our
customers. Determination of 3) and 4) are based on management’s
judgments regarding the fixed nature of our arrangements, taking into account
termination provisions and the collectability of fees under our
arrangements. Should changes in conditions cause management to
determine these criteria are not met for certain future arrangements, revenue
recognized for any reporting period would be adjusted and could be adversely
affected.
In
accordance with Emerging Issues Task Force Issue No. 00-21, “Revenue
Arrangements with Multiple Deliverables”, revenue recognized for any
multiple-element contract is allocated to each element of the arrangement based
on the relative fair value of the element. The determination of fair
value of each element is based on our analysis of objective evidence from
comparable internal or third-parties’ sales of the individual
element. If we are unable to determine evidence of fair value for any
undelivered element of the arrangement, revenue for the arrangement is deferred
and recognized using the revenue recognition method appropriate to the
predominant undelivered element.
Genomics
Services Revenue.
The majority of Genomics services revenue consists of
fees earned under subscription agreements and perpetual licenses for all or
parts of our gene expression databases, the BioExpress System and ToxExpress
System, and software tools. In addition, we derive a smaller but
growing percentage of revenue from providing other services, including
microarray data generation and analysis services, various toxicogenomics reports
and other related services. Revenue from subscription agreements is
recognized ratably over the period during which the customer has access to
the
database. Certain subscription agreements have included a right of
early termination (which, in some instances, is subject to conditions) by the
customer, without penalty, on a specified date prior to the normal expiration
of
the term. If any agreement has a right of early termination, revenue
is recognized ratably over the subscription term up to the possible date of
early termination, based on subscription fees earned under the agreement through
the possible date of early termination. If such early termination
does not occur, the balance of the subscription fees earned under the agreement
is recognized as revenue ratably over the remaining term of the
agreement. Revenue from perpetual licenses to data and software for
which the Company is not obligated to provide continuing support or services
is
recognized when the data and/or software has been delivered. Revenue
from perpetual licenses for which the Company is obligated to provide continuing
support or services is recognized during the period such support or services
are
performed. Revenue from other services, including our data generation
and analysis services, is recognized when the services are
performed. Our agreements generally provide for termination in the
event of a breach of the agreement by either party or a bankruptcy or insolvency
of either party.
Periodically,
we enter into contractual arrangements with multiple deliverables. If
we are unable to determine objectively and reliably the fair value of individual
undelivered elements, we recognize all revenue using the revenue recognition
method appropriate to the predominant undelivered element. We also
defer the direct and incremental expenses associated with the delivery of
services for which revenue has been deferred and recognize these expenses as
we
recognize the related revenue. The timing of revenue recognition
associated with agreements we enter into in future periods may also be dependent
on our ability to objectively and reliably determine the fair value of
deliverables included in those agreements.
GOODWILL
AND OTHER INTANGIBLE ASSSETS IMPAIRMENT
We’ve
previously recorded value for goodwill and other intangible assets, including
licenses to technologies or data, patent costs and software development and
database upgrade costs. The determination of whether or not these
other intangible assets are impaired involves significant judgment, including
the following: (i) our licenses and internally developed intellectual property
may not provide valid and economical competitive advantage or may become
obsolete; and (ii) services may become obsolete before we recover the costs
incurred in connection with their development.
Under
Statement of Financial Accounting Standards No. 142, “Goodwill and Other
Intangible Assets”, we are required to perform an annual impairment test of our
goodwill and periodic reviews of our other intangible assets. In
addition, we are required to test for impairment at any point we have an
indication that impairment may exist. We have elected to perform our
annual impairment test of goodwill as of October 1. The goodwill
impairment test that we have historically selected consisted of a ten-year
discounted cash flow analysis, including the determination of a terminal value,
and required management to make various judgments and assumptions, including
revenue growth rates and discount rates, which management believed to be
reasonable.
As
part of
our annual testing of goodwill in 2006, we determined that no impairment existed
in the carrying value of goodwill of our Genomics Division. However,
due to the restructuring of our Genomics Division, we recorded impairment
charges of $1.3 million in the third quarter of 2006 for certain intangible
assets which we determined would no longer be utilized by our Genomics
Division.
Our
assessment of the fair value of our divisions is dependent on subjective
estimates we make of inherently uncertain future net cash flows, including
estimates of terminal values, estimates of fair value obtained in a formal
sales
process or in the recent case of the Genomics Division, the sale price under
an
agreement to sell such assets. Accordingly, our estimates of future
net cash flows may change as market conditions and circumstances
dictate. In connection with the sale of our Genomics Assets, we
expect a majority of the carrying value of our goodwill as of September 30,
2007
will be allocated to the disposition of such assets. Future
impairment tests of goodwill and other intangibles may result in additional
impairment charges based on changing estimates.
ACCOUNTS
RECEIVABLE AND UNBILLED SERVICES
Our
ability to collect outstanding receivables and unbilled services from our
customers is critical to our operating performance and cash
flows. Typically, arrangements with our customers require that the
payments for our services be made in advance, based upon the achievement of
milestones or in accordance with predetermined payment schedules. We
have an allowance for doubtful accounts based on our estimate of accounts
receivable that are at risk of collection. If the financial condition
of our customers were to deteriorate, resulting in an impairment of their
ability to make payments, an increase in the allowance for doubtful accounts
may
be required.
INVENTORY
We
maintain an inventory of microarrays and reagents used to generate genomic
data
for our databases and for services in our Genomics Division. This
inventory is valued at the lower of cost or market. Certain items in
inventory may be considered impaired, obsolete, or excessive and as such, we
may
establish an allowance to reduce the carrying value of these items to their
net
realizable value. Based on certain estimates, assumptions and
judgments made from information available at the time, we determine the
appropriate amount of any such inventory allowance. If these
estimates or assumptions, or the market for the use of our microarrays and
reagents change, we may be required to record additional reserves.
EQUITY
INVESTMENTS
We
hold an
equity investment in one company (Xceed Molecular, formerly MetriGenix
Corporation) with a remaining book value of $3.0 million as of September 30,
2007. We record an investment impairment charge when it is believed
that an investment has experienced a decline in value that is
other-than-temporary. Future adverse changes in market conditions or
poor operating results of the underlying investee could result in our inability
to recover the carrying value of this investment that may not be reflected
in
such an investment’s current carrying value, thereby possibly requiring an
impairment charge in the future.
STOCK-BASED
COMPENSATION
In
the
first quarter of 2006, we adopted Statement of Financial Accounting Standards
No. 123 (revised 2004), “Share-Based Payment” (“SFAS 123R”). SFAS
123R requires us to expense the fair value of stock-based compensation awards
of
our various stock-based compensation programs over the requisite service period
of the award. We estimate the fair value of our stock-based
compensation using fair value pricing models which require the use of
significant assumptions for expected volatility of our common stock, life of
stock options and forfeiture rates. Future adverse changes in such
assumptions could result in us recording increased stock-based compensation
expenses for stock-based compensation awards granted/issued in the
future.
RECENTLY
ISSUED ACCOUNTING PRONOUNCEMENTS
In
September 2006, the Financial Accounting Standards Board (“FASB”) issued
Statement of Financial Accounting Standards No. 157, “Fair Value Measurements”
(“SFAS 157”). SFAS 157 defines fair value, establishes a framework
for measuring fair value under generally accepted accounting principles and
expands disclosures about fair value measurements. SFAS 157
emphasizes that fair value is a market-based measurement, not an entity-specific
measurement, and states that a fair value measurement should be determined
based
on the assumptions that market participants would use in pricing the asset
or
liability. This Statement applies under other accounting
pronouncements that require or permit fair value measurements, for which the
FASB previously concluded in such accounting pronouncements that fair value
is
the relevant measurement attribute. Accordingly, this Statement does
not require any new fair value measurements. SFAS No. 157 is
effective for fiscal years beginning after November 15, 2007, which we intend
to
adopt on January 1, 2008. We are currently evaluating the impact, if
any, that SFAS 157 will have on our financial position, results of operations
and cash flows, but do not believe the effect will be material.
In
June
2006, the FASB issued Interpretation No. 48, “Accounting for Uncertainty in
Income Taxes” (“FIN 48”). FIN 48 clarifies the accounting for
uncertainty in income taxes in an enterprise’s financial statements in
accordance with SFAS No. 109, “Accounting for Income Taxes”. FIN 48
prescribes a minimum recognition threshold and measurement attribute for
financial statement recognition and measurement of a tax position. If
a tax position does not meet the more-likely-than-not initial recognition
threshold, the benefit would not be recorded in the financial
statements. We adopted FIN 48 on January 1, 2007; the adoption did
not have a material effect on us.
If
applicable, we would recognize interest and penalties related to income tax
matters in income tax expense. No interest and penalties were
recognized in the Consolidated Condensed Statements of Operations for the three
and nine months ended September 30, 2007 and the Consolidated Condensed Balance
Sheet at September 30, 2007. We and our subsidiaries file
consolidated and separate income tax returns in the United States and in a
number of state and foreign jurisdictions. We are subject to tax
examinations in our major tax jurisdictions for all years since
inception.