|
Filed
Pursuant to Rule 424(b)(3) |
PROSPECTUS |
Registration
No. 333-260338 |
Up
to 1,755,000 Ordinary Shares Underlying Previously Issued Warrants
NeuroSense
Therapeutics Ltd.
This
prospectus relates to the issuance of up to (i) 1,655,000 of our ordinary shares, no par value per share (the “ordinary shares”)
issuable upon the exercise of warrants that were issued as part of an initial public offering (the “Public Warrants”), at
an exercise price of $6.00 per ordinary share and (ii) 100,000 ordinary shares issuable upon the exercise of warrants that were issued
to the underwriters of our initial public offering at an exercise price of $7.50 per ordinary share (the “Underwriter Warrants”).
Our
ordinary shares trade on the Nasdaq Capital Market, or Nasdaq, under the symbol “NRSN”, and our Public Warrants trade on
the Nasdaq under the symbol “NRSNW”. On December 4, 2023, the last reported sale price of our ordinary shares on Nasdaq was
$1.49 per ordinary share.
We
are an “emerging growth company” and a “foreign private issuer” as defined under the U.S. federal securities
laws, and as such, are eligible for reduced public company disclosure requirements. See “Prospectus Summary—Implications
of Being an Emerging Growth Company and a Foreign Private Issuer” for additional information.
Investing
in our securities is highly speculative and involves a high degree of risk. See “Risk Factors” beginning on page 5 to read
about factors you should consider before buying any of our ordinary shares.
Neither
the Securities and Exchange Commission nor any other regulatory body has approved or disapproved of these securities or passed upon the
accuracy or adequacy of the disclosures in this prospectus. Any representation to the contrary is a criminal offense.
Prospectus
dated December 4, 2023
TABLE
OF CONTENTS
ABOUT
THIS PROSPECTUS
This
prospectus is part of the registration statement on Form F-1 that we filed with the Securities and Exchange Commission (the “SEC”)
for the issuance of the ordinary shares covered by this prospectus.
You
should not assume that the information contained in, or incorporated by reference into, this prospectus is accurate on any date subsequent
to the date set forth on the front cover of this prospectus, even though this prospectus is delivered or ordinary shares covered by this
prospectus are sold or otherwise disposed of on a later date. It is important for you to read and consider all information contained
in, or incorporated by reference into, this prospectus in making your investment decision. You should also read and consider the information
in the documents to which we have referred you under the caption “Where You Can Find Additional Information” in this prospectus.
We
have not authorized anyone to provide any information or to make any representation other than those contained in, or incorporated by
reference into, this prospectus. You must not rely upon any information or representation not contained in, or incorporated by reference
into, this prospectus. This prospectus does not constitute an offer to sell or the solicitation of an offer to buy any of our securities
other than the securities covered hereby, nor does this prospectus constitute an offer to sell or the solicitation of an offer to buy
any securities of the Company in any jurisdiction to any person to whom it is unlawful to make such offer or solicitation in such jurisdiction.
This
prospectus, including the information incorporated by reference herein, contains forward-looking statements that are subject to a number
of risks and uncertainties, many of which are beyond our control. See “Risk Factors” and “Cautionary Note Regarding
Forward-Looking Statements.”
Unless
otherwise indicated or the context otherwise requires, all references in this prospectus to the terms “NeuroSense,” “NeuroSense
Therapeutics,” the “Company,” “we,” “us” and “our” refer to NeuroSense Therapeutics
Ltd. In this prospectus, any reference to any provision of any legislation shall include any amendment, modification, re-enactment or
extension thereof. Words importing the singular shall include the plural and vice versa, and words importing the masculine gender shall
include the feminine or neutral gender.
TRADEMARKS,
SERVICE MARKS AND TRADENAMES
The
NeuroSense Therapeutics logo and other trademarks and service marks of NeuroSense Therapeutics Ltd. appearing in this prospectus or the
information incorporated by reference herein are the property of the Company. Solely for convenience, some of the trademarks, service
marks, logos and trade names referred to in this prospectus are presented without the® and™ symbols,
but such references are not intended to indicate, in any way, that we will not assert, to the fullest extent under applicable law, our
rights to these trademarks, service marks and trade names. This prospectus, including the information incorporated by reference herein,
contains additional trademarks, service marks and trade names of others. All trademarks, service marks and trade names appearing in this
prospectus or the information incorporated by reference herein are, to our knowledge, the property of their respective owners. We do
not intend our use or display of other companies’ trademarks, service marks, copyrights or trade names to imply a relationship
with, or endorsement or sponsorship of us by, any other companies.
MARKET
AND INDUSTRY DATA
This
prospectus, including the information incorporated by reference herein, contains industry, market and competitive position data that
are based on industry publications and studies conducted by third parties as well as our own internal estimates and research. These industry
publications and third-party studies generally state that the information that they contain has been obtained from sources believed to
be reliable, although they do not guarantee the accuracy or completeness of such information. While we believe that each of these publications
and third-party studies is reliable, we have not independently verified the market and industry data obtained from these third-party
sources. Forecasts and other forward-looking information obtained from these sources are subject to the same qualifications and uncertainties
as the other forward-looking statements included in, or incorporated by reference into, this prospectus. While we believe our internal
research is reliable and the definition of our market and industry are appropriate, neither such research nor these definitions have
been verified by any independent source.
CAUTIONARY
NOTE REGARDING FORWARD-LOOKING STATEMENTS
This
prospectus and certain information incorporated by reference herein contain forward-looking statements within the meaning of Section 27A
of the Securities Act and Section 21E of the U.S. Securities Exchange Act of 1934, as amended (the “Exchange Act”),
and other securities laws. Many of the forward-looking statements contained in, or incorporated by reference into, this prospectus can
be identified by the use of forward-looking words such as “anticipate,” “believe,” “could,” “estimate,”
“expect,” “intend,” “may,” “might,” “plan,” “potential,” “should,”
“target,” “would” and other similar expressions that are predictions of or indicate future events and future
trends, although not all forward-looking statements contain these identifying words.
Forward-looking
statements are based on our management’s beliefs and assumptions and on information currently available to our management. Such
statements are subject to substantial risks and uncertainties, and actual results may differ materially from those expressed or implied
in the forward-looking statements due to a variety of factors, including, but not limited to, those identified under the section titled
“Risk Factors” in this prospectus or the documents incorporated herein. These risks and uncertainties include factors relating
to:
|
● |
the going concern reference
in our financial statements and our need for substantial additional financing to achieve our goals; |
|
● |
our limited operating history
and history of incurring significant losses and negative cash flows since our inception, which we anticipate will continue for the
foreseeable future; |
|
● |
our dependence on the success
of our lead product candidate, PrimeC, including our obtaining of regulatory approval to market PrimeC in the United States; |
|
● |
our limited experience
in conducting clinical trials and reliance on clinical research organizations and others to conduct them; |
|
● |
our ability to advance
our preclinical product candidates into clinical development and through regulatory approval; |
|
● |
the results of our clinical
trials, which may fail to adequately demonstrate the safety and efficacy of our product candidates; |
|
● |
our ability to achieve
the broad degree of physician adoption and use and market acceptance necessary for commercial success; |
|
● |
our reliance on third parties
in marketing, producing or distributing products and research materials for certain raw materials, compounds and components necessary
to produce PrimeC for clinical trials and to support commercial scale production of PrimeC, if approved; |
|
● |
our receipt of regulatory
clarity and approvals for our therapeutic candidates and the timing of other regulatory filings and approvals; |
|
● |
estimates of our expenses,
revenues, capital requirements and our needs for additional financing; |
|
● |
our efforts to obtain,
protect or enforce our patents and other intellectual property rights related to our product candidates and technologies; |
|
● |
our ability to maintain
the listing of our ordinary shares on Nasdaq; |
|
● |
the impact of the public
health, political and security situation in Israel, the U.S. and other countries in which we may obtain approvals for our products
or our business; and |
|
● |
the impacts on our ongoing
and planned trials and manufacturing as a result of the war in Israel. |
The
preceding list is not intended to be an exhaustive list of all of our risks and uncertainties. As a result of these factors, we cannot
assure you that the forward-looking statements contained in, or incorporated by reference into, this prospectus will prove to be accurate.
Furthermore, if our forward-looking statements prove to be inaccurate, the inaccuracy may be material. In light of the significant uncertainties
in these forward-looking statements, you should not regard these statements as a representation or warranty by us or any other person
that we will achieve our objectives and plans in any specified time frame, or at all.
In
addition, statements that “we believe” and similar statements reflect our beliefs and opinions on the relevant subject. These
statements are based upon information available to us as of the date of this prospectus or any document incorporated herein or therein,
and while we believe such information forms a reasonable basis for such statements, such information may be limited or incomplete, and
our statements should not be read to indicate that we have conducted an exhaustive inquiry into, or review of, all relevant information.
PROSPECTUS
SUMMARY
This
summary highlights selected information about us and the ordinary shares being offered. It may not contain all of the information that
may be important to you. Before investing in the ordinary shares, you should read this entire prospectus and other information incorporated
by reference from our other filings with the SEC carefully for a more complete understanding of our business and this offering, including
our consolidated financial statements and the section entitled “Risk Factors” included or incorporated by reference in this
prospectus.
Overview
We
are a clinical-stage biotechnology company focused on discovering and developing treatments for patients suffering from neurodegenerative
diseases, including Amyotrophic Lateral Sclerosis (“ALS”), Alzheimer’s disease (“AD”) and Parkinson’s
disease (“PD”). We believe these diseases represent some of the most significant unmet medical needs of our time, with limited
effective therapeutic options available. The burden of these diseases on both patients and society is substantial. For example, the average
annual cost of ALS alone is $180,000 per patient, and its estimated annual burden on the U.S. healthcare system is greater than
$1 billion. Due to the complexity of neurodegenerative diseases, our strategy is utilizing a combined therapeutic approach to target
multiple disease-related pathways.
Our
lead therapeutic candidate, PrimeC, is a novel extended-release oral formulation, fixed-dose combination of two FDA-approved drugs, ciprofloxacin
and celecoxib. PrimeC is designed to treat ALS by modulating microRNA synthesis, iron accumulation, and neuroinflammation, all of which
are hallmarks of ALS pathology. The U.S. Food and Drug Administration (“FDA”) and the European Medicines Agency (“EMA”)
have granted PrimeC orphan drug designation for the treatment of ALS. In addition, the EMA has granted PrimeC the Small and Medium-Sized
Enterprise (SME) status, which offers significant potential benefits leading up to and following drug regulatory approval. We believe
PrimeC’s multifactorial mechanism of action has the potential to significantly prolong lifespan and improve ALS patients’
quality of life, thereby reducing the burden of this debilitating disease on both patients and healthcare systems.
PrimeC
is currently being evaluated in PARADIGM (“NST003”), a Phase IIb randomized, multi-center, multinational, prospective,
double-blind, placebo-controlled study, to evaluate safety, tolerability, and efficacy of PrimeC in 69 people living with ALS. Participants
are being administered PrimeC or placebo at a 2:1 ratio, respectively. Study participants are allowed to continue standard of care treatment
of approved products. The primary endpoints of the study are an evaluation of ALS-biomarkers as well as safety and tolerability assessment.
Secondary and exploratory endpoints are the evaluation of clinical efficacy (ALS Functional Rating Scale — Revised and
slow vital capacity), survival, and improvement in quality of life. All subjects who complete the six-month double-blind, placebo-controlled
dosing period are transferred to the PrimeC active arm for a 12-month open label extension. The study completed enrollment in May 2023,
enrolling 69 participants living with ALS in Israel, Italy, and Canada. On November 6, 2023, we announced that we had completed dosing
of the last patient in the double-blind segment of the study. We anticipate reporting clinical efficacy (secondary endpoints) and safety
and tolerability (primary endpoints) results of the double-blind segment of the trial in December 2023. We also expect to report on another
primary endpoint, the assessment of ALS-biomarkers, TDP-43 and Prostagladin2, in the first half of 2024.
Since
the FDA had requested additional non-clinical data to support the overall duration of the PARADIGM trial, as PrimeC is intended for long-term
administration in the treatment of ALS, we withdrew the protocol from its investigational new drug application (“IND”) in
order to align our clinical strategy with the FDA, and we intend to discuss a potential trial design for an ALS pivotal trial with the
FDA. Subject to agreement with FDA on trial design, the results of the PARADIGM trial and results of additional studies we intend to
conduct in the interim, we believe we could be in a position to initiate a pivotal clinical trial of PrimeC for the treatment of ALS
as early as 2024. On November 13, 2023, we announced that we had concluded a successful Type D meeting with the FDA regarding chemistry,
manufacturing, and controls (“CMC”) development plans in advance of an expected Phase 3 pivotal study and potential subsequent
marketing approval. The FDA agreed with our proposed CMC development plan.
PrimeC
was previously evaluated in a Phase IIa clinical trial (“NST002”) in 15 people living with ALS, conducted at the Tel
Aviv Sourasky Medical Center, Israel. The primary endpoint of the NST002 trial, which was safety and tolerability, was met. In this trial,
the safety profile observed was consistent with known safety profiles of ciprofloxacin and celecoxib. Side effects were mild and transient
in nature. There were no new or unexpected safety signals detected during the trial.
Additionally,
we observed positive clinical signals in comparison to virtual controls, and a serum biomarker analysis showed significant changes following
treatment, indicating biological activity of the drug in comparison to untreated matched ALS patients. All 12 patients who completed
the NST002 trial elected to continue into an extension study with PrimeC, that was conducted as an Investigator Initiated Study. To date,
the Company is still supporting the drug supply for a few of the participants in this study, which is over than 40 months since
NST002 was initiated.
We
completed three additional studies in 2022 as part of our drug development program to further support our future regulatory submissions.
In April 2022, we initiated a pharmacokinetic (“PK”) study (“NCT05232461”) of PrimeC. The PK open-label,
randomized, single-dose, three-treatment, three-period crossover study evaluated the effect of food on the bioavailability of PrimeC
as compared to the bioavailability of co-administered ciprofloxacin tablets and celecoxib capsules in adult subjects in the U.S. under
an FDA cleared IND protocol.
In
August 2022, we completed enrollment and dosing of all subjects in a multi-dose PK study (“NCT05436678”). On September 28,
2022, we released the results of the NCT05436678 study. Based on results, we believe the PK profile of PrimeC supports the formulation’s
extended-release properties, as the concentrations of the active components have been synchronized, aiming to potentially maximize the
synergism between the two compounds. In June 2022, we reported the successful completion of the “in-life” phase of its
90-day GLP toxicology study. In this study, the components of PrimeC, celecoxib and ciprofloxacin, were administered to rodents at doses
4x the maximal clinical dose. All animals appeared normal, with no significant findings observed. The Company intends to present the
data from these studies to the FDA as part of PrimeC’s drug development plan.
We
believe we have a strong patent estate, including patents on method of use, combination, and formulation. We secured U.S. Patent
10,980,780 relating to methods for treatment of ALS using ciprofloxacin and celecoxib, the components of PrimeC, which expires in 2038.
This patent also been issued in the European Patent Office, Canada, Australia, Israel and Japan. We also expect to take advantage of
orphan drug exclusivity for PrimeC, if approved, for seven years in the United States and ten years in the European Union.
In addition, U.S. patent application 16/623,467, which relates to methods of treatment of neurodegenerative disease using combinations
of ciprofloxacin and celecoxib, is currently pending. This patent application is expected to expire on June 20, 2038.
Our
organization is built around a management team with extensive experience in the pharmaceutical industry, with a particular focus on ALS
research and clinical trials. We believe that our leadership team is well-positioned to lead us through clinical development, regulatory
approval and commercialization of our product candidates.
In
addition to PrimeC, we have conducted research and development efforts in AD and PD, with a similar strategy of combined products. The
following chart represents our current product development pipeline:
In
May 2023, we entered into a Collaborative Evaluation Agreement with Biogen MA Inc. (“Biogen”), a subsidiary of Biogen
Inc., under which Biogen will evaluate the impact of PrimeC on neurofilament levels in the plasma of participants in PARADIGM. Biogen
will fund the neurofilament biomarker study and conduct the analysis. Biogen also received a right of first refusal for a definitive
licensing agreement to co-develop and/or commercialize PrimeC for the treatment of ALS. We expect to report the results of the studies
conducted pursuant to the Collaborative Evaluation Agreement with Biogen in the first quarter of 2024.
Corporate
Information
Our
legal and commercial name is NeuroSense Therapeutics Ltd. We were incorporated on February 13, 2017 and were registered as a private
company limited by shares under the laws of the State of Israel. We completed our initial public offering on the Nasdaq in December 2021.
The ordinary shares and warrants to purchase ordinary shares are traded on the Nasdaq under the symbol “NRSN” and “NRSNW,”
respectively.
Our
principal executive offices are located at 11 HaMenofim Street, Building B, Herzliya, 4672562 Israel, and our telephone number is +972-9-7996183.
Our website address is www.neurosense-tx.com. The information on our website does not constitute a part of this prospectus. Our
agent for service of process in the United States is Cogency Global Inc., 122 East 42nd Street, 18th Floor,
New York, NY 10168.
Implications
of Being an Emerging Growth Company
As
a company with less than $1.235 billion in revenue during our last fiscal year, we are an “emerging growth company”
as defined in the Jumpstart Our Business Startups Act of 2012 (the “JOBS Act”). As such, we may take advantage
of certain exemptions from various reporting requirements that are applicable to other publicly traded entities that are not emerging
growth companies. These exemptions include:
|
● |
not being required to have
our registered independent public accounting firm attest to management’s assessment of our internal control over financial
reporting; |
|
● |
not being required to comply
with any requirement that may be adopted by the Public Company Accounting Oversight Board (“PCAOB”), regarding mandatory
audit firm rotation or a supplement to the auditor’s report providing additional information about the audit and the financial
statements (i.e., an auditor discussion and analysis); |
|
● |
not being required to submit
certain executive compensation matters to stockholder advisory votes, such as “say-on-pay,” “say-on-frequency”
and “say-on-golden parachutes”; |
|
● |
the audit reports of our
independent registered public accounting firm do not require communication of critical audit matters; and |
|
● |
not being required to disclose
certain executive compensation related items such as the correlation between executive compensation and performance and comparisons
of the chief executive officer’s compensation to median employee compensation. |
As
a result, the information contained in this prospectus and the documents incorporated by reference herein may be different from the information
you receive from other public companies in which you hold shares. We may take advantage of these provisions for up until we are no longer
an emerging growth company. We would cease to be an emerging growth company upon the earliest to occur of: (i) the last day
of the first fiscal year in which our annual gross revenues exceed $1.235 billion; (ii) the date on which we have issued more
than $1 billion in non-convertible debt securities during the previous three years; (iii) the date on which we are deemed
to be a “large accelerated filer” as defined in Rule 12b-2 under the Exchange Act; or (iv) the last day
of the fiscal year following the fifth anniversary of our initial public offering.
Implications
of Being a Foreign Private Issuer
We
are also a non-U.S. company with foreign private issuer status. Even after we no longer qualify as an emerging growth company, as
long as we continue to qualify as a foreign private issuer under the Exchange Act, we will be exempt from certain provisions of
the Exchange Act that are applicable to U.S. domestic public companies, including:
|
● |
the rules under the Exchange Act
requiring domestic filers to issue financial statements prepared under U.S. generally accepted accounting principles (“U.S. GAAP”); |
|
● |
the sections of the Exchange Act
regulating the solicitation of proxies, consents or authorizations in respect of a security registered under the Exchange Act; |
|
● |
the sections of the Exchange Act
requiring insiders to file public reports of their share ownership and trading activities and liability for insiders who profit from
trades made in a short period of time; and |
|
● |
the rules under the Exchange Act
requiring the filing with the SEC of quarterly reports on Form 10-Q containing unaudited financial statements and other specified
information, and current reports on Form 8-K upon the occurrence of specified significant events. |
Notwithstanding
these exemptions, we will file with the SEC, within four months after the end of each fiscal year, or such applicable time as required
by the SEC, an Annual Report on Form 20-F containing financial statements audited by an independent registered public accounting
firm.
We
may take advantage of these exemptions until such time as we are no longer a foreign private issuer. We would cease to be a foreign private
issuer at such time as more than 50% of our outstanding voting securities are held by U.S. residents and any of the following three
circumstances applies: (i) the majority of our executive officers or directors are U.S. citizens or residents; (ii) more
than 50% of our assets are located in the United States; or (iii) our business is administered principally in the United States.
Both
foreign private issuers and emerging growth companies also are exempt from certain more stringent executive compensation disclosure rules.
Thus, even if we no longer qualify as an emerging growth company, but remain a foreign private issuer, we will continue to be exempt
from the more stringent compensation disclosures required of companies that are neither an emerging growth company nor a foreign private
issuer.
THE
OFFERING
Securities
offered by us |
|
Up to 1,755,000
ordinary shares, upon the exercise of Warrants |
|
|
|
Ordinary
shares outstanding prior to this offering |
|
13,666,042 ordinary shares |
|
|
|
Ordinary shares outstanding immediately after this
offering |
|
15,421,042 ordinary shares
if the Warrants offered in this offering are exercised in full. |
|
|
|
Use of Proceeds |
|
We will receive the exercise
price upon any exercise of the Warrants, to the extent exercised on a cash basis. We will receive gross proceeds of approximately
$10.7 million assuming the exercise of all 1,755,000 Warrants for cash. However, the holders of the Warrants are not obligated to
exercise the Warrants, and we cannot predict whether or when, if ever, the holders of the Warrants will choose to exercise the Warrants,
in whole or in part. The exercise price of the Warrants may exceed the trading price of our ordinary shares. Accordingly, we currently
intend to use the proceeds received upon such exercise, if any, for general corporate purposes and working capital. |
|
|
|
Listing |
|
Our ordinary shares trade
on the Nasdaq under the symbol “NRSN”, and our Public Warrants trade on the Nasdaq under the symbol “NRSNW”.
|
|
|
|
Risk factors |
|
You should carefully read
the section titled “Risk Factors” and other information included in this prospectus for a discussion of factors that
you should consider before deciding to invest in our securities. |
Unless
otherwise indicated, the number of ordinary shares outstanding prior to this offering is based on 13,666,042 ordinary shares outstanding
as of September 30, 2023, and excludes:
|
● |
1,093,128 ordinary shares
issuable upon the exercise of options outstanding as of September 30, 2023, at a weighted average exercise price of $2.30 under
our 2018 Employee Share Option Plan; |
|
● |
360,000 ordinary shares
issuable upon the vesting of restricted share units outstanding under our 2018 Share Incentive Plan; |
|
● |
209,543 ordinary shares
reserved for issuance and available for future grant under our 2018 Share Incentive Plan; |
|
● |
1,670,000 ordinary shares
underlying pre-funded warrants with an exercise price of $0.0001 per share issued in connection with our registered direct offering
in June 2023 (all of which have been exercised as of the date of this prospectus); |
|
● |
3,000,000 ordinary shares
underlying warrants with an exercise price of $1.50 per share issued in connection with our registered direct offering in June 2023;
and |
|
● |
1,755,000 ordinary shares
underlying the Warrants to which this prospectus relates. |
Unless
otherwise stated, all information in this prospectus assumes no exercise of the outstanding options or warrants into ordinary shares
as described above.
RISK
FACTORS
Investing
in our securities involves significant risks. Before making an investment decision, you should carefully consider the risks described
below and under the section titled “Item 3. Key Information — D. Risk Factors” in our Annual Report
on Form 20-F for the year ended December 31, 2022 which is incorporated by reference herein, as well as any other information
included or incorporated by reference in this prospectus, together with all of the other information appearing in this prospectus or
incorporated by reference herein, including in light of your particular investment objectives and financial circumstances. The risks
so described are not the only risks we face. Additional risks not presently known to us or that we currently deem immaterial may also
impair our business operations and become material. Our business, financial condition and results of operations could be materially adversely
affected by any of these risks. The trading price of our securities could decline due to any of these risks, and you may lose all or
part of your investment. The discussion of risks includes or refers to forward-looking statements; you should read the explanation of
the qualifications and limitations on such forward-looking statements discussed elsewhere in this prospectus under the caption “Cautionary
Note Regarding Forward-Looking Statements” above.
Risk
Related to our Ordinary Shares
Our
failure to maintain compliance with Nasdaq’s continued listing requirements could result in the delisting of our ordinary shares.
On
September 25, 2023, we received a notice from the Listing Qualifications Department of Nasdaq notifying us that, because the closing
bid price for our ordinary shares had fallen below $1.00 per share for 30 consecutive business days, we no longer meet the minimum bid
price requirement for continued listing on Nasdaq under Nasdaq Listing Rule 5550(a)(2). The notice provided a grace
period of 180 calendar days, or until March 25, 2024, to regain compliance with the minimum closing bid price requirement for continued
listing.
In
order to regain compliance, the closing bid price of the ordinary shares must meet or exceed $1.00 per share for at least ten consecutive
business days during this 180-day grace period. If we do not regain compliance with Rule 5550(a)(2) by March 25, 2024, we may be eligible
for an additional 180-calendar day compliance period. To qualify for the additional 180-calendar day compliance period, we must meet
the continued listing requirement for market value of publicly held shares and all other initial listing standards for the Nasdaq, except
for the minimum bid price requirement, and provide written notice to Nasdaq of our intent to cure the deficiency during this second compliance
period, by effecting a reverse share split, if necessary. However, if it appears to the Nasdaq staff that we will not be able to cure
the deficiency, or if we are otherwise not eligible, Nasdaq will provide notice to us that the ordinary shares will be subject to delisting.
No
assurance can be given that we will be able to comply with the other standards that we are required to meet in order to maintain a listing
on such exchange, such as the minimum stockholders’ equity and minimum market value of publicly held shares, and no assurance can
be given that the price of the ordinary shares will not again be in violation of Nasdaq’s minimum bid price rule in the future.
Our failure to meet these requirements may result in our securities being delisted from Nasdaq.
If
the ordinary shares are delisted from Nasdaq, we may seek to list them on other markets or exchanges or the ordinary shares may trade
on the pink sheets. In the event of such delisting, our shareholders’ ability to trade, or obtain quotations of the market value
of, our ordinary shares would be severely limited because of lower trading volumes and transaction delays. These factors could contribute
to lower prices and larger spreads in the bid and ask prices for our securities. In addition, the substantially decreased trading in
the ordinary shares and decreased market liquidity of the ordinary shares as a result of the loss of market efficiencies associated with
Nasdaq and the loss of federal preemption of state securities laws, which could materially adversely affect our ability to obtain financing
on acceptable terms, if at all, and may result in the potential loss of confidence by investors, suppliers, customers and employees and
fewer business development opportunities. Additionally, the market price of the ordinary shares may decline further and stockholders
may lose some or all of their investment. There can be no assurance that the ordinary shares, if delisted from the Nasdaq in the future,
would be listed on another national or international securities exchange or on a national quotation service, the Over-The-Counter Markets
or the pink sheets.
We
may effect a reverse stock split of our ordinary shares, but it may not result in us obtaining the intended benefits.
We
may be required to seek shareholder approval to effect a reverse share split in order to regain compliance with Nasdaq’s minimum
closing bid price requirement. However, if we do effect a reverse share split, there can be no assurance that the market price
per new ordinary share after the reverse share split will remain unchanged or increase in proportion to the reduction in the number of
old shares outstanding before the reverse share split. Other factors, such as our financial results, market conditions and the market
perception of our business may adversely affect the market price of our ordinary shares, and there can be no assurance that a reverse
share split, if completed, will result in the intended benefits, that the market price of our ordinary shares will increase in proportion
to the reduction in the number of shares outstanding before the reverse share split or that the market price of our ordinary shares will
not decrease in the future. If the market price of our ordinary shares does not increase the price per share above Nasdaq’s minimum
bid price threshold of $1.00 per share or if the market price of our ordinary shares does not remain above Nasdaq’s minimum bid
price threshold of $1.00 per share, our ordinary shares may still be delisted from Nasdaq.
If
we do effect a reverse stock split, the liquidity of our ordinary shares may be affected adversely by any such reverse share split given
the reduced number of shares that will be outstanding following the reverse share split, especially if the market price of our ordinary
shares does not increase as a result of the reverse share split.
Risk
Related to this Offering
The
price of our ordinary shares may be volatile.
The
market price of the ordinary shares has fluctuated in the past. Consequently, the current market price of our ordinary shares may not
be indicative of future market prices, and we may be unable to sustain or increase the value of your investment in our ordinary shares.
Risks
Related to our Operations in Israel
We
conduct some of our operations in Israel. Conditions in Israel, including the recent attack by Hamas and other terrorist organizations
from the Gaza Strip and Israel’s war against them, may affect our operations.
Because
we are incorporated under the laws of the State of Israel, and most of our officers and fourteen out of sixteen of our employees are
residents of Israel, our business and operations are directly affected by economic, political, geopolitical and military conditions in
Israel. Since the establishment of the State of Israel in 1948, a number of armed conflicts have occurred between Israel and its neighboring
countries and terrorist organizations active in the region. These conflicts have involved missile strikes, hostile infiltrations and
terrorism against civilian targets in various parts of Israel, which have negatively affected business conditions in Israel.
In
October 2023, Hamas terrorists infiltrated Israel’s southern border from the Gaza Strip and conducted a series of attacks on civilian
and military targets. Hamas also launched extensive rocket attacks on Israeli population and industrial centers located along Israel’s
border with the Gaza Strip and in other areas within the State of Israel. These attacks resulted in thousands of deaths and injuries,
and Hamas additionally kidnapped many Israeli civilians and soldiers. Following the attack, Israel’s security cabinet declared
war against Hamas and a military campaign against these terrorist organizations commenced in parallel to their continued rocket and terror
attacks. In parallel, border clashes between Israel and the Hezbollah terrorist group on Israel’s northern border with Lebanon
intensified and may escalate into a greater regional conflict.
All
of our clinical and pre-clinical research and development is currently being conducted outside of Israel, other than
our 12-month open label-extension (“OLE”) study of the PARADIGM trial, partially conducted in Tel Aviv, and
a planned Phase 2 trial with PrimeC for Alzheimer’s disease that we plan to conduct in Haifa, Israel.
The OLE has not been affected by the war, although the quality of the study may be adversely affected if as a result of the war patients
are unable to visit the study center or the study coordinator is not able to conduct home visits and monitor the patients. In addition,
in the event of a significant escalation of hostilities in northern Israel, there may be a delay in the planned Alzheimer trial. We
do not believe the planned Alzheimer’s trial will be materially affected by the war and do not anticipate that any such delay as
a result of the war would have a material impact on the Company. We may also elect to set up a site in Israel for a Phase 3 pivotal ALS
trial of PrimeC, but this would be in addition to numerous other sites in Europe and the U.S., and as a result we do not expect the timeline
or quality of this trial to be adversely affected by the war. Our manufacturing is conducted in India. We do not currently anticipate
any disruption to the supply chain relevant to our ongoing clinical trials and believe there are alternative sources of supply from whom
we could obtain the necessary finished drug product to conduct our clinical trials. In addition, we believe we have sufficient finished
product in inventory to continue our ongoing clinical trials for at least the next few months.
The
Israel Defence Force (the “IDF”), the national military of Israel, is a conscripted military service, subject to certain
exceptions. Since October 7, 2023, the IDF has called up several hundred thousand of its reserve forces to serve. Fourteen out of our
current 16 employees are resident in Israel. Three of our five executive officers and four out of 11 other employees who we believe are
performing critical functions reside in Israel. Two of our non-management employees in Israel who do not perform critical functions have
been called, and additional employees may be called, for service in the current or future wars or other armed conflicts with Hamas, and
such persons may be absent for an extended period of time. As a result, our operations in Israel may be disrupted by such absences, which
disruption may materially and adversely affect our business, prospects, financial condition and results of operations.
It
is currently not possible to predict the duration or severity of the ongoing conflict or its effects on our business, operations and
financial conditions. The ongoing conflict is rapidly evolving and developing, and could disrupt our business and operations, and hamper
our ability to raise additional funds or sell our securities, among others.
USE
OF PROCEEDS
We
will receive gross proceeds of approximately $10.7 million assuming the exercise of all 1,755,000 Warrants for cash. We will not receive
any proceeds from the sale of the ordinary shares underlying the Warrants.
However,
the holders of the Warrants are not obligated to exercise the Warrants, and we cannot predict whether or when, if ever, the holders of
the Warrants will choose to exercise the Warrants, in whole or in part. The exercise price of the Warrants may exceed the trading price
of our ordinary shares. If the trading price of the ordinary shares is below $6.00 ($7.50 in the case of the Underwriter Warrants), we
believe that holder of the Warrants will be unlikely to exercise their warrants, resulting in little to no cash proceeds to us. Accordingly,
we currently intend to use the proceeds received upon such exercise, if any, for general corporate purposes and working capital.
MARKET
FOR ORDINARY SHARES AND DIVIDEND POLICY
The
ordinary shares are traded on the Nasdaq Capital Market under the symbol “NRSN.” The last reported sale price of the ordinary
shares on November 30, 2023 on the Nasdaq Capital Market was $1.29 per share. As of November 30, 2023, there were 1,389 shareholders
of record of the ordinary shares.
We
have never declared or paid any cash dividends on the ordinary shares, and we anticipate that, for the foreseeable future, we will retain
any future earnings to support operations and to finance the growth and development of our business. Therefore, we do not expect to pay
cash dividends for at least the next several years.
The
distribution of dividends may also be limited by the Israeli Companies Law, 5759-1999 (the “Companies Law”), which
permits the distribution of dividends only out of retained earnings or earnings derived over the two most recent fiscal years, whichever
is higher, provided that there is no reasonable concern that payment of a dividend will prevent a company from satisfying its existing
and foreseeable obligations as they become due. As of September 30, 2023, we did not have distributable earnings pursuant to the
Companies Law. Dividend distributions may be determined by our board of directors, as our amended and restated articles of association
do not provide that such distributions require shareholder approval.
CAPITALIZATION
The
table below sets forth our total capitalization as of September 30, 2023:
|
● |
on an actual basis; and |
|
● |
on an as adjusted basis
to give effect to the issuance of 1,755,000 ordinary shares upon the exercise of the Warrants for aggregate gross proceeds of approximately
$10.7 million. |
The
financial data in the following table should be read in conjunction with the “Use of Proceeds” section herein, our financial
statements and notes thereto incorporated by reference herein. Our historical results do not necessarily indicate our expected results
for any future periods.
| |
As of September 30,
2023 | |
| |
Actual (in thousands) | | |
As Adjusted | |
Cash | |
$ | 4,759 | | |
| 15,439 | |
| |
| | | |
| | |
Liability in respect to warrants and pre-funded warrants | |
| 2,689 | | |
| 2,479 | |
Shareholders’ equity: | |
| | | |
| | |
Ordinary shares, no par value per share | |
| — | | |
| | |
Share premium and capital reserve | |
| 28,920 | | |
| 39,810 | |
Accumulated deficit | |
| (29,116 | ) | |
| (29,116 | ) |
Total shareholders’ equity | |
| (196 | ) | |
| 10,694 | |
Total capitalization | |
$ | 2,493 | | |
| 13,173 | |
DILUTION
If
you invest in our ordinary shares in this offering, your ownership interest will be diluted to the extent of the difference between the
exercise price per ordinary share and the as adjusted net tangible book value per ordinary share immediately after this offering.
Our
net tangible book value as of September 30, 2023 was approximately $(0.2) million, or $(0.01) per share. Net tangible book value per
ordinary share is determined by dividing our total tangible assets (including our right-of-use lease assets), less total liabilities,
by the number of ordinary shares outstanding as of September 30, 2023. Dilution with respect to net tangible book value per ordinary
share represents the difference between the amount per ordinary share paid by the purchaser of ordinary shares in this offering and the
net tangible book value per ordinary share immediately after this offering.
After
giving effect to the issuance of 1,655,000 ordinary shares upon the exercise of the Public Warrants at an exercise price of $6.00 per
ordinary share and the issuance of 100,000 ordinary shares upon the exercise of the Underwriter Warrants at an exercise price of $7.50
per ordinary share, our as adjusted net tangible book value as of September 30, 2023 would have been approximately $10.7 million, or
$0.69 per ordinary share. This amount represents an increase in the net tangible book value of $0.70 per ordinary share to our existing
shareholders and an immediate dilution in net tangible book value of $5.31 per ordinary share and $6.81 per ordinary share to new investors
exercising Public Warrants and Underwriter Warrants, respectively. The following table illustrates this per ordinary share dilution:
Exercise price per ordinary share
underlying Public Warrants |
|
|
|
|
|
$ |
6.00 |
|
Exercise price per ordinary share underlying Underwriter
Warrants |
|
|
|
|
|
$ |
7.50 |
|
Net tangible book value per
ordinary share as of September 30, 2023 |
|
$ |
(0.01 |
) |
|
|
|
|
Net
increase in net tangible book value per ordinary share attributable to existing shareholders |
|
$ |
0.70 |
|
|
|
|
|
As adjusted net tangible book value per ordinary share
after this offering |
|
|
|
|
|
$ |
0.69 |
|
Dilution in net tangible book value per ordinary share
to new investors exercising Public Warrants |
|
|
|
|
|
$ |
5.31 |
|
Dilution in net tangible book value per ordinary share
to new investors exercising Underwriter Warrants |
|
|
|
|
|
$ |
6.81 |
|
Unless
otherwise indicated, the number of ordinary shares outstanding prior to this offering is based on 13,666,042 ordinary shares outstanding
as of September 30, 2023, and excludes:
|
● |
1,093,128 ordinary shares
issuable upon the exercise of options outstanding as of September 30, 2023, at a weighted average exercise price of $2.30 under
our 2018 Employee Share Option Plan; |
|
● |
360,000 ordinary shares
issuable upon the vesting of restricted share units outstanding under our 2018 Share Incentive Plan; |
|
● |
209,543 ordinary shares
reserved for issuance and available for future grant under our 2018 Share Incentive Plan; |
|
● |
1,670,000 ordinary shares
underlying pre-funded warrants with an exercise price of $0.0001 per share issued in connection with our registered direct offering
in June 2023 (all of which have been exercised as of the date of this prospectus); and |
|
● |
3,000,000 ordinary shares
underlying warrants with an exercise price of $1.50 per share issued in connection with our registered direct offering in June 2023. |
TAXATION
The
following description is not intended to constitute a complete analysis of all tax consequences relating to the acquisition, ownership
and disposition of our securities offered hereby. You should consult your own tax advisor concerning the tax consequences of your particular
situation, as well as any tax consequences that may arise under the laws of any state, local, foreign or other taxing jurisdiction.
Material
United States Federal Income Tax Considerations
The
following discussion describes material United States federal income tax considerations relating to the acquisition, ownership,
and disposition of ordinary shares covered by this prospectus by a U.S. Holder (as defined below) that acquires the ordinary shares
in this offering and holds them as a capital asset. This discussion is based on the tax laws of the United States, including the
Internal Revenue Code of 1986, as amended (the “Code”), the United States Department of the Treasury (“Treasury”)
regulations promulgated or proposed thereunder, and administrative and judicial interpretations thereof, all as in effect on the date
hereof. These tax laws are subject to change, possibly with retroactive effect, and subject to differing interpretations that could affect
the tax consequences described herein. This discussion does not address the tax consequences to a U.S. Holder under the laws of
any state, local or foreign taxing jurisdiction, estate tax consequences, alternative minimum tax consequences, potential application
of the Medicare contribution tax on net investment income, and tax consequences applicable to U.S. Holders subject to special rules,
as discussed below.
For
purposes of this discussion, a “U.S. Holder” is a beneficial owner of the ordinary shares that, for United States
federal income tax purposes, is:
|
● |
an individual who is a
citizen or resident of the United States; |
|
● |
a domestic corporation
(or other entity taxable as a corporation); |
|
● |
an estate the income of
which is subject to United States federal income taxation regardless of its source; or |
|
● |
a trust if (1) a court
within the United States is able to exercise primary supervision over the trust’s administration and one or more United States
persons have the authority to control all substantial decisions of the trust or (2) a valid election under the Treasury regulations
is in effect for the trust to be treated as a United States person. |
This
discussion does not address all aspects of United States federal income taxation that may be applicable to U.S. Holders in
light of their particular circumstances or status (including, for example, banks and other financial institutions, insurance companies,
broker and dealers in securities or currencies, traders in securities that have elected to mark securities to market, regulated investment
companies, real estate investment trusts, partnerships or other pass-through entities and arrangements, corporations that accumulate
earnings to avoid U.S. federal income tax, tax-exempt organizations, pension plans, persons that own or who are treated as constructively
owning 10 percent or more of our stock by vote or by value, persons that hold the ordinary shares as part of a straddle, hedge or other
integrated investment, and persons subject to alternative minimum tax or whose “functional currency” is not the U.S. dollar).
If
a partnership (including any entity or arrangement treated as a partnership for United States federal income tax purposes) holds
the ordinary shares the tax treatment of a person treated as a partner in the partnership for United States federal income tax purposes
generally will depend on the status of the partner and the activities of the partnership. Partnerships (and other entities or arrangements
so treated for United States federal income tax purposes) and their partners should consult their own tax advisors.
This
discussion addresses only U.S. Holders and does not discuss any tax considerations other than United States federal income
tax considerations. Prospective investors are urged to consult their own tax advisors regarding the United States federal, state,
and local, and non-United States tax consequences of the purchase, ownership, and disposition of the ordinary shares.
Dividends
We
do not expect to make any distribution with respect to the ordinary shares. However, if we make any such distribution, under the United States
federal income tax laws, and subject to the passive foreign investment company (“PFIC”) rules discussed below, the gross
amount of any dividend we pay out of our current or accumulated earnings and profits (as determined for United States federal income
tax purposes) will be includible in income for a U.S. Holder and subject to United States federal income taxation. Dividends
paid to a noncorporate U.S. Holder that constitute qualified dividend income will be taxable at a preferential tax rate applicable
to long-term capital gains of, currently, 20 percent, provided that the U.S. Holder holds the ordinary shares for more than 60 days
during the 121-day period beginning 60 days before the ex-dividend date and meets other holding period requirements. If we are treated
as a PFIC, dividends paid to a U.S. Holder will not be treated as qualified dividend income. If we are not treated as a PFIC, dividends
we pay with respect to the ordinary shares generally will be qualified dividend income, provided that the holding period requirements
are satisfied by the U.S. Holder and in the year that the U.S. Holder receives the dividend, the ordinary shares are readily
tradable on an established securities market in the United States.
A
U.S. Holder must include any Israeli tax withheld from the dividend payment in the gross amount of the dividend even though the
holder does not in fact receive it. The dividend is taxable to the holder when the holder of ordinary shares receives the dividend, actually
or constructively. Because we are not a United States corporation, the dividend will not be eligible for the dividends-received
deduction generally allowed to United States corporations in respect of dividends received from other United States corporations.
The amount of the dividend distribution includible in a U.S. Holder’s income will be the U.S. dollar value of the NIS
payments made, determined at the spot NIS/U.S. dollar rate on the date the dividend distribution is includible in income, regardless
of whether the payment is in fact converted into U.S. dollars. Generally, any gain or loss resulting from currency exchange fluctuations
during the period from the date the dividend payment is included in income to the date the payment is converted into U.S. dollars
will be treated as ordinary income or loss and will not be eligible for the special tax rate applicable to qualified dividend income.
The gain or loss generally will be income or loss from sources within the United States for foreign tax credit limitation purposes.
Subject
to certain limitations, the Israeli tax withheld in accordance with the United States Israel Tax Treaty and paid over to Israel
will be creditable or deductible against a U.S. Holder’s United States federal income tax liability, if the U.S. Holder
satisfies certain minimum holding period requirements. Dividends that we distribute generally should constitute “passive category
income,” or, in the case of certain U.S. Holders, “general category income” for foreign tax credit limitation
purposes. The rules relating to the determination of the foreign tax credit limitation are complex, and U.S. Holders should consult
their tax advisor to determine whether and to what extent they will be entitled to a credit for Israeli withholding taxes imposed in
respect of any dividend we distribute.
To
the extent a distribution with respect to the ordinary shares exceeds our current or accumulated earnings and profits, as determined
under United States federal income tax principles, the distribution will be treated, first, as a tax-free return of the U.S. Holder’s
investment, up to the holder’s adjusted tax basis in its ordinary shares, and, thereafter, as capital gain, which is subject to
the tax treatment described below in “— Gain on Sale, Exchange or Other Taxable Disposition of the ordinary shares.”
Gain
on Sale, Exchange or Other Taxable Disposition of the ordinary shares
Subject
to the PFIC rules described below under “— Passive Foreign Investment Company Considerations,” a U.S. Holder
that sells, exchanges or otherwise disposes of ordinary shares in a taxable disposition generally will recognize capital gain or loss
for United States federal income tax purposes equal to the difference between the U.S. Dollar value of the amount realized
and the holder’s tax basis, determined in U.S. Dollars, in the ordinary shares. Gain or loss recognized on such a sale, exchange
or other disposition of ordinary shares generally will be long-term capital gain if the U.S. Holder’s holding period in the
ordinary shares exceeds one year. Long-term capital gains of non-corporate U.S. Holders are generally taxed at preferential rates.
The gain or loss generally will be income or loss from sources within the United States for foreign tax credit limitation purposes.
A U.S. Holder’s ability to deduct capital losses is subject to limitations.
Passive
Foreign Investment Company Considerations
Based
on our income and assets, we believe that we were a PFIC for the preceding taxable year and expect that we will be a PFIC for the current
taxable year. Because the determination of our PFIC status is made annually based on the factual tests described below, however, we cannot
provide any assurances regarding our PFIC status for the current or future taxable years or that the IRS will agree with our conclusion
regarding our PFIC status. If we were classified as a PFIC in any taxable year, a U.S. Holder would be subject to special rules
with respect to distributions on and sales, exchanges and other dispositions of the ordinary shares. We will be treated as a PFIC for
any taxable year in which at least 75 percent of our gross income is “passive income” or at least 50 percent of our gross
assets during the taxable year (based on the average of the fair market values of the assets determined at the end of each quarterly
period) are assets that produce or are held for the production of passive income. Passive income for this purpose generally includes,
among other things, dividends, interest, rents, royalties, gains from commodities and securities transactions, and gains from assets
that produce passive income. However, rents and royalties received from unrelated parties in connection with the active conduct of a
trade or business are not considered passive income for purposes of the PFIC test. In determining whether we are a PFIC, a pro rata portion
of the income and assets of each corporation in which we own, directly or indirectly, at least a 25% interest (by value) is taken into
account.
Excess
Distribution Rules
If
we were a PFIC with respect to a U.S. Holder, then unless the holder makes one of the elections described below under “— QEF
Election” or “— Mark-to-Market Election,” a special tax regime would apply to the U.S. Holder with
respect to (a) any “excess distribution” (generally, aggregate distributions in any year that are greater than 125%
of the average annual distribution received by the holder in the shorter of the three preceding years or the holder’s holding
period for the ordinary shares) and (b) any gain realized on the sale or other disposition of the ordinary shares. Under this regime,
any excess distribution and realized gain will be treated as ordinary income and will be subject to tax as if (a) the excess distribution
or gain had been realized ratably over the U.S. Holder’s holding period, (b) the amount deemed realized in each year
had been subject to tax in each year of that holding period at the highest marginal rate for such year (other than income allocated to
the current period or any taxable period before we became a PFIC, which would be subject to tax at the U.S. Holder’s regular
ordinary income rate for the current year and would not be subject to the interest charge discussed below), and (c) the interest
charge generally applicable to underpayments of tax had been imposed on the taxes deemed to have been payable in those years. In
addition, dividend distributions would not qualify for the lower rates of taxation applicable to long-term capital gains discussed above
under “— Dividends.” For ordinary shares acquired pursuant to the exercise of the Warrants, a U.S. Holder’s
holding period will for this purpose include the holding period of such warrants.
A
U.S. Holder that holds the ordinary shares at any time during a taxable year in which we are classified as a PFIC generally will
continue to treat such ordinary shares, as well as ordinary shares acquired pursuant to an exercise of the Warrants, as ordinary shares
in a PFIC, even if we no longer satisfy the income and asset tests described above, unless the U.S. Holder elects to recognize gain,
which will be taxed under the excess distribution rules as if such ordinary shares had been sold on the last day of the last taxable
year for which we were a PFIC.
Certain
elections by a U.S. Holder would alleviate some of the adverse consequences of PFIC status and would result in an alternative treatment
of the ordinary shares, as described below. However, under U.S. Treasury Regulations applying to warrants with respect to stock
in a PFIC, these elections are not available with respect to the Warrants.
QEF
Election
If
we were a PFIC, the rules above would not apply to a U.S. Holder that timely makes an election to treat the ordinary shares as stock
of a “qualified electing fund” (“QEF”). A U.S. Holder that makes a QEF election is required to include in
income its pro rata share of the ordinary earnings and net capital gain as ordinary income and long-term capital gain, respectively,
subject to a separate election to defer payment of taxes, which deferral is subject to an interest charge.
The
timely QEF election also allows the electing U.S. Holder to: (i) generally treat any gain recognized on the disposition of its shares
of the PFIC as capital gain; (ii) treat its share of the PFIC’s net capital gain, if any, as long-term capital gain instead of
ordinary income; and (iii) either avoid interest charges resulting from PFIC status altogether, or make an annual election, subject to
certain limitations, to defer payment of current taxes on its share of the PFIC’s annual realized net capital gain and ordinary
earnings subject, however, to an interest charge on the deferred tax computed by using the statutory rate of interest applicable to an
extension of time for payment of tax. In addition, net losses (if any) of a PFIC will not pass through to an electing U.S. Holder and
may not be carried back or forward in computing such PFIC’s ordinary earnings and net capital gain in other taxable years. Consequently,
a U.S. Holder may over time be taxed on amounts that as an economic matter exceed our net profits.
A
U.S. Holder’s tax basis in ordinary shares will be increased to reflect QEF income inclusions and will be decreased to reflect
distributions of amounts previously included in income as QEF income inclusions. No portion of the QEF income inclusions attributable
to ordinary income will be treated as qualified dividend income. Amounts included as QEF income inclusions with respect to direct and
indirect investments generally will not be taxed again when distributed. U.S. Holders should consult their tax advisors as to the manner
in which QEF income inclusions affect their allocable share of our income and their basis in their ordinary shares.
A
U.S. Holder makes a QEF election generally by attaching a completed IRS Form 8621 (Information Return by a Shareholder of a
Passive Foreign Investment Company or Qualified Electing Fund) (“IRS Form 8621”) to a timely filed United States
federal income tax return for the year beginning with which the QEF election is to be effective (taking into account any extensions).
A QEF election can be revoked only with the consent of the IRS. In order for a U.S. Holder to make a valid QEF election, we
must annually provide or make available to the holder certain information. While we intend to provide to U.S. Holders the information
required to make a valid QEF election, we cannot provide any assurances that we will in fact provide such information. A QEF election
under the proposed U.S. Treasury Regulations is not available for the Warrants regardless of whether we provide such information
Mark-to-Market
Election
If
we were a PFIC, the rules above also would not apply to a U.S. Holder that makes a “mark-to-market” election with respect
to the ordinary shares, but this election will be available with respect to the ordinary shares only if they meet certain minimum trading
requirements to be considered “marketable stock” for purposes of the PFIC rules. A mark-to-market election under the U.S. Treasury
Regulations is not available for the Warrants.
Ordinary
shares will be marketable stock if they are regularly traded on a national securities exchange that is registered with the SEC or on
a non-U.S. exchange or market that meets certain requirements under the Treasury regulations. Ordinary shares generally will be
considered regularly traded during any calendar year during which they are traded, other than in de minimis quantities, on at
least 15 days during each calendar quarter. Any trades that have as their principal purpose meeting this requirement will be disregarded.
A
U.S. Holder that makes a valid mark-to-market election for the first tax year in which the holder holds (or is deemed to hold) the
ordinary shares and for which we are a PFIC will be required to include each year an amount equal to the excess, if any, of the fair
market value of such shares the U.S. Holder owns as of the close of the taxable year over their adjusted tax basis in such shares.
The U.S. Holder will be entitled to a deduction for the excess, if any, of the U.S. Holder’s adjusted tax basis in the
ordinary shares over the fair market value of such shares as of the close of the taxable year, but only to the extent of any net mark-to-market
gains with respect to such shares included by the U.S. Holder under the election for prior taxable years. The U.S. Holder’s
basis in such ordinary shares will be adjusted to reflect the amounts included or deducted pursuant to the election. Amounts included
in income pursuant to a mark-to-market election, as well as gain on the sale, exchange or other taxable disposition of such ordinary
shares, will be treated as ordinary income. The deductible portion of any mark-to-market loss, as well as loss on a sale, exchange or
other disposition of the ordinary shares to the extent that the amount of such loss does not exceed net mark-to-market gains previously
included in income, will be treated as ordinary loss.
The
mark-to-market election applies to the taxable year for which the election is made and all subsequent taxable years, unless the
ordinary shares cease to be treated as marketable stock for purposes of the PFIC rules or the IRS consents to its revocation. The excess
distribution rules described above generally will not apply to a U.S. Holder for tax years for which a mark-to-market election
is in effect. However, if we were a PFIC for any year in which the U.S. Holder owns the ordinary shares but before a mark-to-market
election is made, the interest charge rules described above would apply to any mark-to-market gain recognized in the year the election
is made.
PFIC
Reporting Obligations
If
we were, or in the future are, a PFIC. a U.S. Holder of the ordinary shares must generally file an annual information return on
IRS Form 8621 containing such information as the Treasury may require. A U.S. Holder’s failure to file the annual information
return will cause the statute of limitations for such U.S. Holder’s U.S. federal income tax return to remain open with regard to
the items required to be included in such report until three years after the U.S. Holder files the annual information return, and, unless
such failure is due to reasonable cause and not willful neglect, the statute of limitations for the U.S. Holder’s entire U.S. federal
income tax return will remain open during such period. U.S. Holders should consult their tax advisors regarding the requirements of filing
such information returns under these rules.
U.S. Holders
are urged to consult their tax advisors as to our status as a PFIC, and the tax consequences to them if we were a PFIC, including the
reporting requirements and the desirability of making, and the availability of, a QEF election or a mark-to-market election with respect
to the ordinary shares .
Medicare
Tax
Non-corporate
U.S. Holders that are individuals, estates or trusts and whose income exceeds certain thresholds generally are subject to a 3.8%
tax on all or a portion of their net investment income, which may include their gross dividend income and net gains from the disposition
of ordinary shares. A United States person that is an individual, estate or trust is encouraged to consult its tax advisors regarding
the applicability of this Medicare tax to its income and gains in respect of any investment in the ordinary shares.
Information
Reporting with Respect to Foreign Financial Assets
Individual
U.S. Holders (and, under regulations, certain entities) may be subject to certain reporting obligations on IRS Form 8938 (Statement
of Specified Foreign Financial Asset) with respect to the ordinary shares for any taxable year during which the U.S. Holder’s
aggregate value of these and certain other “specified foreign financial assets” exceed a threshold amount that varies with
the filing status of the individual or entity. This reporting obligation also applies to domestic entities formed or availed of to hold,
directly or indirectly, specified foreign financial assets, including the ordinary shares. Significant penalties can apply if U.S. Holders
are required to make this disclosure and fail to do so. Such U.S. Holders who fail to timely furnish the required information may be
subject to a penalty. Additionally, if a U.S. Holder does not file the required information, the statute of limitations with respect
to tax returns of the U.S. Holder to which the information relates may not close until three years after such information is filed. U.S.
Holders should consult their tax advisors regarding their reporting obligations with respect to their ownership and disposition of the
ordinary shares .
Information
Reporting and Backup Withholding
In
general, information reporting, on IRS Form 1099, will apply to dividends in respect of ordinary shares and the proceeds from the
sale, exchange or redemption of ordinary shares that are paid to a holder of ordinary shares within the United States (and in certain
cases, outside the United States), unless such holder is an exempt recipient such as a corporation. Backup withholding (currently
at a 24% rate) may apply to such payments if a holder of ordinary shares fails to provide a taxpayer identification number (generally
on an IRS Form W-9) or certification of other exempt status or fails to report in full dividend and interest income.
Backup
withholding is not an additional tax. A U.S. Holder generally may obtain a refund or credit of any amounts withheld under the backup
withholding rules that exceed the U.S. Holder’s income tax liability by timely filing a refund claim with the IRS.
Israeli
Tax Considerations
The
following is a brief summary of certain material Israeli tax laws applicable to us, and certain Israeli government programs that benefit
us. This section also contains a discussion of certain material Israeli tax consequences concerning the ownership and disposition of
our securities offered hereby. This summary does not discuss all the aspects of Israeli tax law that may be relevant to a particular
investor in light of his or her personal investment circumstances or to some types of investors subject to special treatment under Israeli
law. Examples of such investors include residents of Israel or traders in securities who are subject to special tax regimes not covered
in this discussion. To the extent that the discussion is based on tax legislation that has not yet been subject to judicial or administrative
interpretation, we cannot assure you that the appropriate tax authorities or the courts will accept the views expressed in this discussion.
The discussion below is not intended, and should not be construed, as legal or professional tax advice and is not exhaustive of all possible
tax considerations. The discussion is subject to change, including due to amendments under Israeli law or changes to the applicable judicial
or administrative interpretations of Israeli law, which change could affect the tax consequences described below, possibly with a retroactive
effect.
THEREFORE,
YOU ARE URGED TO CONSULT YOUR OWN TAX ADVISORS AS TO THE ISRAELI OR OTHER TAX CONSEQUENCES OF THE PURCHASE, OWNERSHIP AND DISPOSITION
OF OUR SECURITIES OFFERED HEREBY, INCLUDING, IN PARTICULAR, THE EFFECT OF ANY FOREIGN, STATE OR LOCAL TAXES.
General
Corporate Tax Structure in Israel
Israeli
companies are generally subject to corporate tax at a flat rate. In December 2016, the Israeli Parliament approved the Economic
Efficiency Law (Legislative Amendments for Applying the Economic Policy for the 2017 and 2018 Budget Years) (“EEL”)
which reduced the corporate income tax rate from 25% to 24% effective from January 1, 2017, and to 23% effective from January 1,
2018 and thereafter. However, the effective tax rate payable by a company that derives income from an Approved Enterprise, a Preferred
Enterprise, a Benefited Enterprise or a Technological Enterprise (as discussed below) may be considerably less. Capital gains derived
by an Israeli company are generally subject to corporate tax rate.
Law
for the Encouragement of Industry (Taxes), 5729-1969
The
Law for the Encouragement of Industry (Taxes), 5729-1969, generally referred to as the Industry Encouragement Law (“IEL”)
provides several tax benefits for “Industrial Companies.” We may qualify as an Industrial Company within the meaning of the
IEL.
The
IEL defines an “Industrial Company” as an Israeli resident-company, of which 90% or more of its income in any tax year, other
than income from certain government loans, capital gains, interest and dividends, is derived from an “Industrial Enterprise”
owned by it and located in Israel or in the “Area,” in accordance with the definition under Section 3A of the Israeli
Income Tax Ordinance (New Version) 1961 (the “Ordinance”). An “Industrial Enterprise” is defined as an enterprise
whose principal activity in a given tax year is industrial production.
The
following are the main tax benefits available to Industrial Companies:
|
● |
Amortization of the cost
of purchased patent, rights to use a patent, and know-how, which are used for the development or advancement of the Industrial Enterprise,
over an eight-year period, commencing on the year in which such rights were first exercised; |
|
● |
Under limited conditions,
an election to file consolidated tax returns with controlled Israeli Industrial Companies; and |
|
● |
Expenses related to a public
offering are deductible in equal amounts over three years commencing on the year of the offering. |
Eligibility
for benefits under the Industry Encouragement Law is not contingent upon approval of any governmental authority.
Tax
Benefits and Grants for Research and Development
Israeli
tax law allows, under certain conditions, a tax deduction for expenditures related to scientific research and development projects, including
capital expenditures, for the year in which they are incurred. Expenditures are deemed related to scientific research and development
projects, if:
|
● |
The research and expenditures
are approved by the relevant Israeli government ministry, determined by the field of research; |
|
● |
The research and development
must be for the promotion of the company; and |
|
● |
The research and development
is carried out by or on behalf of the company seeking such tax deduction. |
The
amount of such deductible expenses is reduced by the sum of any funds received through government grants for the finance of such scientific
research and development projects. No deduction under these research and development deduction rules is allowed if such deduction is
related to an expense invested in an asset depreciable under the general depreciation rules of the Ordinance. Expenditures that are unqualified
under the conditions above are deductible, under certain conditions, in equal amounts over three years.
From
time to time we may apply to the Israel Innovation Authority (“IIA”) for approval to allow a tax deduction for all or most
of research and development expenses during the year incurred. There can be no assurance that such application will be accepted. If we
will not be able to deduct research and development expenses during the year of the payment, we may be able to deduct research and development
expenses in equal amounts over a period of three years commencing in the year of the payment of such expenses.
Law
for the Encouragement of Capital Investments, 5719-1959
The
Law for the Encouragement of Capital Investments, 5719-1959 (“the Investment Law”) provides certain incentives for capital
investments in production facilities (or other eligible assets). Generally, an investment program that is implemented in accordance with
the provisions of the Investment Law, referred to as an Approved Enterprise, a Beneficiary Enterprise, a Preferred Enterprise, a Preferred
Technological Enterprise, or a Special Preferred Technological Enterprise, is entitled to benefits as discussed below. These benefits
may include cash grants from the Israeli government and tax benefits, based upon, among other things, the geographic location in Israel
of the facility in which the investment is made. In order to qualify for these incentives, the Company is required to comply with the
requirements of the Investment Law.
The
Investment Law was significantly amended effective as of April 1, 2005 (“the 2005 Amendment”), as of January 1,
2011 (the “2011 Amendment”), and as of January 1, 2017 (the “2017 Amendment”). Pursuant to the 2005 Amendment,
tax benefits granted in accordance with the provisions of the Investment Law prior to its revision by the 2005 Amendment remain in force
but any benefits granted subsequently are subject to the provisions of the amended Investment Law. Similarly, the 2011 Amendment introduced
new benefits to replace those granted in accordance with the provisions of the Investment Law in effect prior to the 2011 Amendment.
However, companies entitled to benefits under the Investment Law as in effect prior to January 1, 2011 were entitled to choose to
continue to enjoy such benefits, provided that certain conditions are met, or elect instead, irrevocably, to forego such benefits and
have the benefits of the 2011 Amendment apply. The 2017 Amendment introduces new benefits for Technological Enterprises, alongside the
existing tax benefits.
Tax
Benefits Under the 2011 Amendment
The
2011 Amendment cancelled the availability of the benefits granted to Industrial Companies under the Investment Law prior to 2011 and,
instead, introduced new benefits for income generated by a “Preferred Company” through its “Preferred Enterprise”
(as such terms are defined in the Investment Law) as of January 1, 2011. The definition of a Preferred Company includes a company
incorporated in Israel that is not fully owned by a governmental entity, and that has, among other things, Preferred Enterprise status
and is controlled and managed from Israel. Pursuant to the 2011 Amendment, a Preferred Company is entitled to a reduced corporate tax
rate of 15% with respect to its income derived by its Preferred Enterprise in 2011 and 2012, unless the Preferred Enterprise is located
in a specified development zone, in which case the rate will be 10%. Under the 2011 Amendment, such corporate tax rate was reduced from
15% and 10%, respectively, to 12.5% and 7%, respectively, in 2013, 16% and 9% respectively, in 2014, 2015 and 2016, and 16% and 7.5%,
respectively, in 2017 and thereafter. Income derived by a Preferred Company from a “Special Preferred Enterprise” (as such
term is defined in the Investment Law) would be entitled, subject to certain conditions and during a benefits period of 10 years,
to further reduced tax rates of 8%, or 5% if the Special Preferred Enterprise is located in a certain development zone.
Dividends
distributed from income which is attributed to a “Preferred Enterprise” will be subject to tax at the following rates: (i) Israeli
resident corporations–0% (although, if such dividends are subsequently distributed to individuals or a non-Israeli company the
below rates detailed in sub sections (ii) and (iii) shall apply); (ii) Israeli resident individuals–20%; or (iii) non-Israeli
residents (individuals and corporations)–20%, subject to a reduced tax rate under the provisions of any applicable tax treaty.
The withholding tax rate applicable to distribution of dividend from such income to non-Israeli residents is 25% (or 30% if distributed
to a “substantial shareholder” at the time of the sale or at any time during the preceding twelve months period, as
defined below), which may be reduced under an applicable tax treaty by applying in advance for a withholding certificate from the Israel
Tax Authority (“ITA”). A “substantial shareholder” is generally a person who alone or together with such person’s
relative or another person who collaborates with such person on a permanent basis, holds, directly or indirectly, at least 10% of any
of the “Means of Control” of the corporation. “Means of control” generally include the right to vote, receive
profits, nominate a director or an executive officer, receive assets upon liquidation, or order someone who holds any of the aforesaid
rights how to act, regardless of the source of such right.
The
2011 Amendment also provided transitional provisions to address companies already enjoying existing tax benefits under the Investment
Law. These transitional provisions provide, among other things, that unless an irrevocable request is made to apply the provisions of
the Investment Law as amended in 2011 with respect to income to be derived as of January 1, 2011, a Beneficiary Enterprise can elect
to continue to benefit from the benefits provided to it before the 2011 Amendment came into effect, provided that certain conditions
are met.
New
Tax Benefits Under the 2017 Amendment That Became Effective on January 1, 2017
The
2017 Amendment was enacted as part of the EEL that was published on December 29, 2016 and is effective as of January 1, 2017.
The 2017 Amendment provides new tax benefits for two types of “Technological Enterprises,” as described below, and is in
addition to the other existing tax beneficial programs under the Investment Law.
The
2017 Amendment provides that a Preferred Company satisfying certain conditions will qualify as having a “Preferred Technological
Enterprise” and will thereby enjoy a reduced corporate tax rate of 12% on income that qualifies as “Preferred Technological
Income,” as defined in the Investment Law. The corporate tax rate is further reduced to 7.5% with respect to a Preferred Technological
Enterprise located in development zone “A.” In addition, a Preferred Company who qualifies as having a “Preferred Technological
Enterprise” will enjoy a reduced corporate tax rate of 12% on capital gain derived from the sale of certain “Benefitted Intangible
Assets” (as defined in the Investment Law) to a related foreign company if the Benefitted Intangible Assets were acquired from
a foreign company on or after January 1, 2017 for at least NIS 200 million, and the sale receives prior approval from the IIA.
The
2017 Amendment further provides that a Preferred Company satisfying certain conditions (including group consolidated revenues of at least
NIS 10 billion) will qualify as having a “Special Preferred Technological Enterprise” and will thereby enjoy a reduced
corporate tax rate of 6% on “Preferred Technological Income” regardless of the company’s geographic location within
Israel. In addition, a Special Preferred Technological Enterprise will enjoy a reduced corporate tax rate of 6% on capital gain derived
from the sale of certain “Benefitted Intangible Assets” to a related foreign company if the Benefitted Intangible Assets
were either developed by the Special Preferred Enterprise or acquired from a foreign company on or after January 1, 2017, and the
sale received prior approval from the IIA. A Special Preferred Technological Enterprise that acquires Benefitted Intangible Assets
from a foreign company for more than NIS 500 million will be eligible for these benefits for at least ten years, subject to
certain approvals as specified in the Investment Law.
Dividends
distributed by a Preferred Technological Enterprise or a Special Preferred Technological Enterprise, paid out of Preferred Technological
Income, are generally subject to tax at the rate of 20% or such lower rate as may be provided in an applicable tax treaty. The withholding
tax rate applicable to distribution of dividend from such income to non-Israeli residents is 25% (or 30% if distributed to a “substantial
shareholder” at the time of the sale or at any time during the preceding twelve months period), which may be reduced under
an applicable tax treaty by applying in advance for a withholding certificate from the ITA. In addition, if such dividends are distributed
to a foreign company that holds solely or together with other foreign companies 90% or more in the Israeli company and other conditions
are met, the withholding tax rate will be 4% (subject to the receipt in advance of a valid certificate from the ITA allowing for a reduced
tax rate). However, if such dividends are paid to an Israeli company, no tax is required to be withheld.
Taxation
of Our Securityholders
Capital
gains Tax on Sales of the ordinary shares
Israeli
law generally imposes a capital gains tax on the sale of any capital assets by Israeli residents, as defined for Israeli tax purposes,
and on the sale of capital assets located in Israel, including shares of Israeli companies, by both Israeli residents and non-Israeli
residents, unless a specific exemption is available or unless a tax treaty between Israel and the shareholder’s country of residence
provides otherwise. The Ordinance distinguishes between real gain and inflationary surplus. The inflationary surplus is a portion of
the total capital gain equivalent to the increase of the relevant asset’s purchase price attributable to an increase in the Israeli
consumer price index, or, in certain circumstances, a foreign currency exchange rate, between the date of purchase and the date of sale.
Inflationary surplus is currently not subject to tax in Israel. The real gain is the excess of the total capital gain over the inflationary
surplus.
Capital
Gains Taxes Applicable to Non-Israeli Resident Securityholders
A
non-Israeli resident who derives capital gains from the sale of shares or warrants in an Israeli resident company that were purchased
after the company was listed for trading on a stock exchange outside of Israel, will be exempt from Israeli tax as long as (among other
conditions) the securities were not held through a permanent establishment that the non-resident maintains in Israel. However, non-Israeli
corporations will not be entitled to the foregoing exemption if Israeli residents: (i) have a controlling interest of more than
25% in such non-Israeli corporation or (ii) are the beneficiaries of, or are entitled to, 25% or more of the revenues or profits
of such non-Israeli corporation, whether directly or indirectly. In addition, such exemption is not applicable to a person whose gains
from selling or otherwise disposing of the securities are deemed to be business income.
Additionally,
a sale of securities by a non-Israeli resident may be exempt from Israeli capital gains tax under the provisions of an applicable tax
treaty. For example, under the Convention Between the Government of the United States of America and the Government of the State
of Israel with respect to Taxes on Income, as amended, or the U.S. Israel Tax Treaty, the sale, exchange or other disposition of
shares by a shareholder who is a United States resident (for purposes of the treaty) holding the shares as a capital asset and is
entitled to claim the benefits afforded to such a resident by the U.S. Israel Tax Treaty (a “U.S. Resident”) is
generally exempt from Israeli capital gains tax unless: (i) the capital gain arising from such sale, exchange or disposition is
attributed to real estate located in Israel; (ii) the capital gain arising from such sale, exchange or disposition is attributed
to royalties; (iii) the capital gain arising from the such sale, exchange or disposition is attributed to a permanent establishment
in Israel, under certain terms; (iv) such U.S. Resident holds, directly or indirectly, shares representing 10% or more of the
voting capital during any part of the 12 month period preceding the disposition, subject to certain conditions; or (v) such U.S. Resident
is an individual and was present in Israel for 183 days or more during the relevant taxable year. In any such case, the sale, exchange
or disposition of such shares by the U.S. Resident would be subject to Israeli tax (unless exempt under the Israeli domestic law
as described above). Under the U.S. Israel Tax Treaty, the gain may be treated as foreign source income for United States foreign
tax credit purposes, upon an election by the U.S. Resident, and such U.S. Resident may be permitted to claim a credit for such
taxes against the United States federal income tax imposed on such sale, subject to the limitations under the United States
federal income tax laws applicable to foreign tax credits. The U.S. Israel Tax Treaty does not provide such credit against any United States
state or local taxes.
Regardless
of whether securityholders may be liable for Israeli tax on the sale of our securities, the payment of the consideration may be subject
to the withholding of Israeli tax at source. Securityholders may be required to demonstrate that they are exempt from tax on their capital
gains in order to avoid withholding at source at the time of sale (i.e., provide a non-Israeli resident certificate and other documentation).
Capital
Gains Taxes Applicable to Israeli Resident Securityholders
An
Israeli resident corporation who derives capital gains from the sale of shares or warrants in an Israeli resident company will generally
be subject to tax on the real capital gains generated on such sale at the corporate tax rate (currently of 23%). An Israeli resident
individual will generally be subject to capital gain tax at the rate of 25%. However, if the individual securityholder is claiming deduction
of interest expenditures or is a “substantial shareholder” at the time of the sale or at any time during the preceding twelve months
period, such gain will be taxed at the rate of 30%. Individual holders dealing in securities in Israel for whom the income from the sale
of securities is considered “business income” as defined in section 2(1) of the Ordinance are taxed at the marginal
tax rates applicable to business income (up to 47% in 2023 plus 3% Surtax). Certain Israeli institutions who are exempt from tax under
section 9(2) or section 129(C)(a)(1) of the Ordinance (such as exempt trust funds and pension funds) may be exempt from capital
gains tax from the sale of the securities.
Taxation
of Israeli Shareholders on Receipt of Dividends
An
Israeli resident individual is generally subject to Israeli income tax on the receipt of dividends paid on the ordinary shares at the
rate of 25%. With respect to a person who is a “substantial shareholder” at the time of receiving the dividend or on any
time during the preceding twelve months, the applicable tax rate is 30%. Such dividends are generally subject to Israeli withholding
tax at a rate of 25% if the shares are registered with a nominee company (whether the recipient is a substantial shareholder or not).
If the recipient of the dividend is an Israeli resident corporation such dividend income will be exempt from tax provided the income
from which such dividend is distributed was derived or accrued within Israel and was received directly or indirectly from another corporation
that is liable to Israeli corporate tax. An exempt trust fund, pension fund or other entity that is exempt from tax under section 9(2) or
section 129C(a)(1) of the Ordinance is exempt from tax on a dividend.
Dividend
distribution by a Preferred Technology Enterprise or a Special Preferred Technology Enterprise is subject to beneficial withholding tax
rates. For a further discussion, see “Taxation and Government Programs — Israeli Tax Considerations — Law
for the Encouragement of Capital Investments, 5719-1959 — New Tax Benefits Under the 2017 Amendment that Became Effective
on January 1, 2017.”
Taxation
of Non-Israeli Shareholders on Receipt of Dividends
Non-Israeli
residents (either individuals or corporations) are generally subject to Israeli income tax on the receipt of dividends paid on the ordinary
shares at the rate of 25%, which tax will be withheld at source, unless relief is provided in a treaty between Israel and the shareholder’s
country of residence. With respect to a person who is a “substantial shareholder” at the time of receiving the dividend or
on any time during the preceding twelve months, the applicable tax rate is 30%. Such dividends are generally subject to Israeli
withholding tax at a rate of 25% if the shares are registered with a nominee company (whether the recipient is a substantial shareholder
or not), unless a reduced rate is provided under an applicable tax treaty (subject to the receipt in advance of a valid certificate from
the ITA allowing for a reduced tax rate). For example, under the U.S. Israel Tax Treaty, the maximum rate of tax withheld at source
in Israel on dividends paid to a holder of the ordinary shares who is a U.S. Resident is 25%. However, generally, the maximum rate
of withholding tax on dividends, not generated by a Preferred Technological Enterprise, Preferred Enterprise, Approved Enterprise or
Beneficial Enterprise, that are paid to a United States corporation holding 10% or more of the outstanding voting capital throughout
the tax year in which the dividend is distributed as well as during the previous tax year, is 12.5%, provided that not more than 25%
of the gross income for such preceding year consists of certain types of dividends and interest. Notwithstanding the foregoing, dividends
distributed from income attributed to an Approved Enterprise, Preferred Technological Enterprise, Benefited Enterprise or Preferred Enterprise
are not entitled to such reduction under the tax treaty but are subject to a withholding tax rate of 15% for a shareholder that is a
U.S. corporation, provided that the conditions related to the outstanding voting rights and the gross income for the previous year
(as set forth in the previous sentences) are met. If the dividend is attributable partly to income derived from an Approved Enterprise,
Preferred Technological Enterprise, Benefited Enterprise or Preferred Enterprise, and partly to other sources of income, the withholding
rate may be a blended rate reflecting the relative portions of the two types of income. We cannot assure you that we will designate the
profits that we may distribute in a way that will reduce shareholders’ tax liability.
Application
for the reduced tax rate requires appropriate documentation presented and specific instruction received from the ITA. To the extent
tax is withheld at source at the maximum rates (see above), a qualified tax treaty recipient will have to comply with some administrative
procedures with the ITA in order to receive a refund of any excess tax withheld.
A
foreign resident who had income from a dividend that was accrued from Israeli source, from which, among other conditions, the full tax
was deducted, will be exempt from filing a tax return in Israel, unless (i) such income was generated from a business conducted in Israel
by such foreign resident, (ii) such foreign resident has other taxable sources of income in Israel with respect to which a tax return
is required to be filed, or (iii) such foreign resident is liable to Surtax (see below) in accordance with section 121B of the Ordinance.
Dividend
distribution by a Preferred Technology Enterprise or a Special Preferred Technology Enterprise is subject to beneficial withholding tax
rates. For a further discussion, see “Taxation and Government Programs — Israeli Tax Considerations — Law
for the Encouragement of Capital Investments, 5719-1959 — New Tax benefits Under the 2017 Amendment that Became Effective
on January 1, 2017.”
Surtax
Subject
to the provisions of an applicable tax treaty, individuals who are subject to tax in Israel are also subject to an additional tax at
a rate of 3% on annual income (including, but not limited to, dividends, interest and capital gain) exceeding NIS 698,280 for 2023, which
amount is linked to the annual change in the Israeli consumer price index.
Estate
and Gift Tax
Israeli
law presently does not impose estate or gift taxes.
DESCRIPTION
OF SECURITIES
The
securities to be registered on this registration statement on Form F-1 of which this prospectus forms a part include up to an aggregate
amount of 1,655,000 ordinary shares issuable upon exercise of the Public Warrants at the exercise price of $6.00 per ordinary share and
100,000 ordinary shares issuable upon exercise of the Underwriter Warrants at an exercise price of $7.50 per ordinary share issued as
part of our initial public offering.
Ordinary
shares
The
Company’s authorized share capital consists of 60,000,000 ordinary shares, no par value per share, of which 13,666,042 ordinary
shares were issued and outstanding as of September 30, 2023.
All
of the outstanding ordinary shares are validly issued, fully paid and non-assessable. The ordinary shares are not redeemable and do not
have any pre-emptive rights.
Voting
Rights and Conversion
All
ordinary shares will have identical voting and other rights in all respects. None of our major shareholders have different voting rights
than our other shareholders.
Transfer
of Shares
Fully
paid ordinary shares are issued in registered form and may be freely transferred under the Company’s amended and restated articles
of association, unless the transfer is restricted or prohibited by another instrument, applicable law or the rules of a stock exchange
on which the shares are listed for trading. The ownership or voting of the ordinary shares by non-residents of Israel is not restricted
in any way by the amended and restated articles of association or the laws of the State of Israel, except for ownership by nationals
of some countries that are, or have been, in a state of war with Israel.
Liability
to Further Capital Calls
Our
board of directors may make, from time to time, such calls as it may deem fit upon shareholders with respect to any sum unpaid with respect
to ordinary shares held by such shareholders, which is not payable at a fixed time. Such shareholder shall pay the amount of every call
so made upon him. Unless otherwise stipulated by our board of directors, each payment in response to a call shall be deemed to constitute
a pro rata payment on account of all shares with respect to which such call was made. A shareholder shall not be entitled to his rights
as shareholder, including the right to dividends, unless such shareholder has fully paid all the notices of call delivered to him, or
which according to the Company’s amended and restated articles of association are deemed to have been delivered to him, together
with interest, linkage and expenses, if any, unless otherwise determined by our board of directors.
Business
Combinations
Under
the Company’s amended and restated articles of association, we may not engage in any “business combinations” with any
“interested shareholder” for a three-year period following the time that such shareholder became an interested shareholder,
unless:
|
● |
prior to the time that
such shareholder became an interested shareholder, our board of directors approved either the business combination or the transaction
which resulted in the shareholder becoming an interested shareholder; |
|
● |
upon consummation of the
transaction which resulted in the shareholder becoming an interested shareholder, the interested shareholder owned at least 85% of
our voting shares outstanding at the time the transaction commenced, excluding for purposes of determining our voting shares outstanding
(but not the outstanding voting shares owned by the interested shareholder) those shares owned by persons who are directors
and also officers; or |
|
● |
at the time that such shareholder
became an interested shareholder, or subsequent to such time, the business combination is approved by our board of directors and
authorized at a general meeting of shareholders by the affirmative vote of at least 662/3% of our voting shares outstanding that
are not owned by the interested shareholder. |
Generally,
a “business combination” includes any merger, consolidation, sale or other transaction resulting in a financial benefit to
the interested shareholder. Subject to certain exceptions, an “interested shareholder” is any person (other than the Company
and any of the Company’s direct or indirect majority-owned subsidiaries) who, together with such person’s affiliates and
associates, owns, or within the previous three years owned, 15% or more of our voting shares.
Under
certain circumstances, this provision will make it more difficult for a person who would be an “interested shareholder” to
effect various business combinations with a corporation for a three-year period. This provision may encourage companies interested in
acquiring us to negotiate in advance with our board of directors because the shareholder approval requirement would be avoided if our
board of directors approves either the business combination or the transaction which results in the shareholder becoming an interested
shareholder. These provisions also may have the effect of preventing changes in our board of directors and may make it more difficult
to accomplish transactions which shareholders may otherwise deem to be in their best interests.
Election
of Directors
The
ordinary shares do not have cumulative voting rights for the election of directors. As a result, the holders of a majority of the voting
power represented at a shareholders meeting have the power to elect our directors, subject to the special approval requirements for external
directors under the Companies Law. Under the Company’s amended and restated articles of association, the number of directors on
our board of directors must be no less than three and no more than nine, including any external directors required to be appointed under
the Companies Law. The minimum and maximum number of directors may be changed, at any time and from time to time, by a special vote of
the holders of at least 662/3% of the outstanding shares.
Other
than external directors, for whom special election requirements apply under the Companies Law, the vote required to appoint a director
is a simple majority vote. In addition, under the Company’s amended and restated articles of association, our board of directors
may elect new directors to fill vacancies (whether such vacancy is due to a director no longer serving or due to the number of directors
serving being less than the maximum required in our amended and restated articles of association), provided that the total number of
directors shall not, at any time, exceed nine directors and provided that our board of directors may not elect external directors. The
Company’s amended and restated articles of association provide that the term of a director appointed by our board of directors
to fill any vacancy will be for the remaining term of office of the director(s) whose office(s) have been vacated. Furthermore,
under the Company’s amended and restated articles of association, our directors, other than external directors, are divided into
three classes with staggered three-year terms. Each class of directors consists, as nearly as possible, of 1/3 of the total number of
directors constituting the entire board of directors (other than the external directors).
External
directors are elected for an initial term of three years, may be elected for additional three-year terms, and may be removed from
office pursuant to the terms of the Companies Law.
Dividend
and Liquidation Rights
We
may declare a dividend to be paid to the holders of the ordinary shares in proportion to their respective shareholdings. Under the Companies
Law, dividend distributions are determined by our board of directors and do not require the approval of the shareholders of a company
unless the Company’s articles of association provide otherwise. The Company’s amended and restated articles of association
to be effective immediately prior to the closing of this offering do not require shareholder approval of a dividend distribution and
provide that dividend distributions may be determined by our board of directors.
Pursuant
to the Companies Law, the distribution amount is limited to the greater of retained earnings or earnings generated over the previous
two years, according to our then last reviewed or audited financial statements (less the amount of previously distributed dividends,
if not reduced from the earnings), provided that the end of the period to which the financial statements relate is not more than six months
prior to the date of the distribution. If the Company does not meet such criteria, then the Company may distribute dividends only with
court approval. In each case, the Company is only permitted to distribute a dividend if our board of directors and, if applicable, the
court determines that there is no reasonable concern that payment of the dividend will prevent us from satisfying our existing and foreseeable
obligations as they become due. In the event of our liquidation, after satisfaction of liabilities to creditors, our assets will be distributed
to the holders of the ordinary shares in proportion to their shareholdings. This right, as well as the right to receive dividends, may
be affected by the grant of preferential dividend or distribution rights to the holders of a class of shares with preferential rights
that may be authorized in the future.
Exchange
Controls
There
are currently no Israeli currency control restrictions on remittances of dividends on the ordinary shares, proceeds from the sale of
ordinary shares or interest or other payments to non-residents of Israel, except for shareholders who are subjects of certain countries
that are, or have been, in a state of war with Israel at such time.
Shareholder
Meetings
Under
Israeli law, the Company is required to hold an annual general meeting of our shareholders once every calendar year that must be held
no later than 15 months after the date of the previous annual general meeting. All general meetings other than the annual meeting
of shareholders are referred to in our amended and restated articles of association as special meetings. Our board of directors may call
special meetings whenever it sees fit, at such time and place, within or outside of Israel, as it may determine. In addition, the Companies
Law provides that our board of directors is required to convene a special general meeting upon the written request of (i) any two
of our directors or one-quarter of the members of our board of directors or (ii) one or more shareholders holding, in the aggregate,
either (a) 5% or more of our outstanding issued shares and 1% or more of our outstanding voting power or (b) 5% or more of
our outstanding voting power.
Under
Israeli law, one or more shareholders holding at least 1% of the voting rights at the general meeting may request that the board of directors
include a matter in the agenda of a general meeting to be convened in the future, such as nominating a director candidate, provided that
it is appropriate to discuss such a matter at the general meeting. The Company’s amended and restated articles of association contain
procedural guidelines and disclosure items with respect to the submission of shareholder proposals for shareholders meetings.
Subject
to the provisions of the Companies Law and the regulations promulgated thereunder, shareholders entitled to participate and vote at general
meetings are the shareholders of record on a date to be decided by the board of directors, which may be between four and 40 days
prior to the date of the meeting. Furthermore, the Companies Law requires that resolutions regarding, among other things, the following
matters must be passed at a general meeting of our shareholders:
|
● |
amendments to our amended
and restated articles of association; |
|
● |
appointment or termination
of our auditors; |
|
● |
election of directors,
including external directors (unless otherwise determined in our amended and restated articles of association); |
|
● |
approval of certain related
party transactions; |
|
● |
increases or reductions
of our authorized share capital; |
|
● |
the exercise of our board
of directors’ powers by a general meeting, if our board of directors is unable to exercise its powers and the exercise of any
of its powers is required for our proper management. |
Under
our amended and restated articles of association, we are not required to give notice to our registered shareholders pursuant to the Companies
Law, unless otherwise required by law. The Companies Law requires that a notice of any annual general meeting or special general meeting
be provided to shareholders at least 21 days prior to the meeting and if the agenda of the meeting includes the appointment or removal
of directors, the approval of transactions with office holders or interested or related parties, or an approval of a merger, or as otherwise
required under applicable law, notice must be provided at least 35 days prior to the meeting. Under the Companies Law, shareholders
of a public company are not permitted to take action by written consent in lieu of a meeting.
Voting
Rights
Quorum
Requirements
Pursuant
to the Company’s amended and restated articles of association, holders of the ordinary shares have one vote for each Ordinary Share
held on all matters submitted to a vote before the shareholders at a general meeting. Under the Company’s amended and restated
articles of association, the quorum required for general meetings of shareholders must consist of at least two shareholders present in
person or by proxy (including by voting deed) holding 25% or more of our voting rights. A meeting adjourned for lack of a quorum will
generally be adjourned to the same day of the following week at the same time and place, or to such other day, time or place
as indicated by our board of directors if so specified in the notice of the meeting. At the reconvened meeting, any number of shareholders
present in person or by proxy shall constitute a lawful quorum.
Vote
Requirements
The
Company’s amended and restated articles of association provide that all resolutions of our shareholders require a simple majority
vote, unless otherwise required by the Companies Law or by our amended and restated articles of association. The Company’s amended
and restated articles of association provide that all resolutions of our board of directors require a simple majority vote of the directors
present and voting at such meeting, unless otherwise required by the Companies Law or by the Company’s amended and restated articles
of association. Pursuant to the Company’s amended and restated articles of association, in the event the vote is tied, the chair
of the board of directors will have a casting vote.
Pursuant
to the Company’s amended and restated articles of association, an amendment to the Company’s amended and restated articles
of association regarding any change of the composition or election procedures of our directors will require a special majority vote (66⅔%).
In addition, any change to the rights and privileges of the holders of any class of our shares requires a simple majority of the class
so affected (or otherwise in accordance with the terms of such class), in addition to the simple majority vote of all classes of shares
voting together as a single class at a shareholder meeting.
Under
the Companies Law, each of (i) the approval of an extraordinary transaction with a controlling shareholder and (ii) the terms
of employment or other engagement of the controlling shareholder of the company or such controlling shareholder’s relative (even
if not extraordinary) requires the approval based on the codified fiduciary duties that the office holders owe to a company in the Companies
Law. Certain transactions with respect to remuneration of our office holders and directors require further approvals the approval based
on the codified fiduciary duties that the office holders owe to a company in the Companies Law. Another exception to the simple majority
vote requirement is a resolution for the voluntary winding up, or an approval of a scheme of arrangement or reorganization, of the company
pursuant to Section 350 of the Companies Law, which requires the approval of holders of 75% of the voting rights represented at
the meeting, in person or by proxy and voting on the resolution.
Access
to Corporate Records
Under
the Companies Law, shareholders are provided access to: minutes of our general meetings; our shareholders register and material shareholders
register; the Company’s amended and restated articles of association; our financial statements; and any document that we are required
by law to file publicly with the Israeli Companies Registrar (the “ISA”). In addition, shareholders may request to be provided
with any document related to an action or transaction requiring shareholder approval under the related party transaction provisions of
the Companies Law. We may deny this request if we believe it has not been made in good faith or if such denial is necessary to protect
our interest or protect a trade secret or patent.
Modification
of Class Rights
Under
the Companies Law and the Company’s amended and restated articles of association, the rights attached to any class of share, such
as voting, liquidation and dividend rights, may be amended by adoption of a resolution by the holders of a majority of the shares of
that class present at a separate class meeting, or otherwise in accordance with the terms of such class of shares, in addition to the
simple majority vote of all classes of shares voting together as a single class at a shareholder meeting, as set forth in our amended
and restated articles of association.
Acquisitions
Under Israeli Law
Full
Tender Offer. A person wishing to acquire shares of an Israeli public company and who would as a result hold over 90% of the target
company’s issued and outstanding share capital is required by the Companies Law to make a tender offer to all of the company’s
shareholders for the purchase of all of the issued and outstanding shares of the company. A person wishing to acquire shares of an Israeli
public company and who would as a result hold over 90% of the issued and outstanding share capital of a certain class of shares is required
to make a tender offer to all of the shareholders who hold shares of the relevant class for the purchase of all of the issued and outstanding
shares of that class. If the shareholders who do not accept the offer hold less than 5% of the issued and outstanding share capital of
the company or of the applicable class, and more than half of the shareholders who do not have a personal interest in the offer accept
the offer, all of the shares that the acquirer offered to purchase will be transferred to the acquirer by operation of law. However,
a tender offer will also be accepted if the shareholders who do not accept the offer hold less than 2% of the issued and outstanding
share capital of the company or of the applicable class of shares.
Upon
a successful completion of such a full tender offer, any shareholder that was an offeree in such tender offer, whether such shareholder
accepted the tender offer or not, may, within six months from the date of acceptance of the tender offer, petition an Israeli court
to determine whether the tender offer was for less than fair value and that the fair value should be paid as determined by the court.
However, under certain conditions, the offeror may include in the terms of the tender offer that an offeree who accepted the offer will
not be entitled to petition the Israeli court as described above.
If
(a) the shareholders who did not respond or accept the tender offer hold at least 5% of the issued and outstanding share capital
of the company or of the applicable class or the shareholders who accept the offer constitute less than a majority of the offerees that
do not have a personal interest in the acceptance of the tender offer or (b) the shareholders who did not accept the tender offer
hold 2% or more of the issued and outstanding share capital of the company (or of the applicable class), the acquirer may not acquire
shares of the company that will increase its holdings to more than 90% of the company’s issued and outstanding share capital or
of the applicable class from shareholders who accepted the tender offer.
Special
Tender Offer. The Companies Law provides that an acquisition of shares of an Israeli public company must be made by means of a special
tender offer if as a result of the acquisition the purchaser would become a holder of 25% or more of the voting rights in the company.
Similarly, the Companies Law provides that an acquisition of shares in a public company must be made by means of a special tender offer
if as a result of the acquisition the purchaser would become a holder of more than 45% of the voting rights in the company. These requirements
do not apply if, in general, the acquisition (1) was made in a private placement that received shareholder approval, (2) was
from a 25% or greater shareholder of the company which resulted in the acquirer becoming a 25% or greater shareholder of the company,
or (3) was from a 45% or greater shareholder of the company which resulted in the acquirer becoming a 45% or greater shareholder
of the company.
A
special tender offer must be extended to all shareholders of a company but the offeror is not required to purchase shares representing
more than 5% of the voting power attached to the company’s outstanding shares, regardless of how many shares are tendered by shareholders.
A special tender offer may be consummated only if (i) at least 5% of the voting power attached to the company’s outstanding
shares will be acquired by the offeror and (ii) the number of shares tendered in the offer exceeds the number of shares whose holders
objected to the offer (excluding the purchaser and its controlling shareholders, holders of 25% or more of the voting rights in the company
or any person having a personal interest in the acceptance of the tender offer or any other person acting on their behalf, including
the relatives and entities under such person’s control). If a special tender offer is accepted, then the purchaser or any person
or entity controlling it or under common control with the purchaser or such controlling person or entity may not make a subsequent tender
offer for the purchase of shares of the target company and may not enter into a merger with the target company for a period of one year
from the date of the offer, unless the purchaser or such person or entity undertook to effect such an offer or merger in the initial
special tender offer.
Merger.
The Companies Law permits merger transactions if approved by each party’s board of directors and, unless certain requirements
described under the Companies Law are met, by a majority vote of each party’s shares, and, in the case of the target company, a
majority vote of each class of its shares, voted on the proposed merger at a shareholders meeting.
For
purposes of the shareholder vote, unless a court rules otherwise, the merger will not be deemed approved if a majority of the votes of
shares represented at the shareholders meeting that are held by parties other than the other party to the merger, or by any person (or
group of persons acting in concert) who holds (or hold, as the case may be) 25% or more of the voting rights or the right to appoint
25% or more of the directors of the other party, vote against the merger. If, however, the merger involves a merger with a company’s
own controlling shareholder or if the controlling shareholder has a personal interest in the merger, then the merger is instead subject
to the same special majority approval that governs all extraordinary transactions with controlling shareholders. See “Management — Approval
of Related Party Transactions under Israeli Law — Fiduciary Duties of Directors and Officers — Disclosure
of Personal Interests of an Office Holder and Approval of Certain Transactions.”
If
the transaction would have been approved by the shareholders of a merging company but for the separate approval of each class or the
exclusion of the votes of certain shareholders as provided above, a court may still approve the merger upon the request of holders of
at least 25% of the voting rights of a company, if the court holds that the merger is fair and reasonable, taking into account the value
to the parties to the merger and the consideration offered to the shareholders of the company.
Upon
the request of a creditor of either party to the proposed merger, the court may delay or prevent the merger if it concludes that there
exists a reasonable concern that, as a result of the merger, the surviving company will be unable to satisfy the obligations of the merging
entities, and may further give instructions to secure the rights of creditors.
In
addition, a merger may not be consummated unless at least 50 days have passed from the date on which a proposal for approval of
the merger was filed by each party with the IRC and at least 30 days have passed from the date on which the merger was approved
by the shareholders of each party.
Israeli
tax law treats some acquisitions, such as share-for-share exchanges between an Israeli company and a foreign company, less favorably
than U.S. tax laws. For example, Israeli tax law may, under certain circumstances, subject a shareholder who exchanges his ordinary
shares for shares in another corporation to taxation prior to the sale of the shares received in such share-for-share swap.
Anti-Takeover
Measures Under Israeli Law
The
Companies Law allows us to create and issue shares having rights different from those attached to the ordinary shares, including shares
providing certain preferred rights with respect to voting, distributions or other matters and shares having pre-emptive rights. As of
the date of this prospectus, no preferred shares were authorized under the Company’s amended and restated articles of association.
In the future, if we do authorize, create and issue a specific class of preferred shares, such class of shares, depending on the specific
rights that may be attached to it, may have the ability to frustrate or prevent a takeover or otherwise prevent our shareholders from
realizing a potential premium over the market value of their ordinary shares. The authorization and designation of a class of preferred
shares will require an amendment to the Company’s amended and restated articles of association, which requires the prior approval
of the holders of a majority of the voting power attaching to our issued and outstanding shares at a general meeting. The convening of
the meeting, the shareholders entitled to participate and the majority vote required to be obtained at such a meeting will be subject
to the requirements set forth in the Companies Law as described above in “— Voting Rights.”
Borrowing
Powers
Pursuant
to the Companies Law and the Company’s amended and restated articles of association, our board of directors may exercise all powers
and take all actions that are not required under law or under our amended and restated articles of association to be exercised or taken
by our shareholders, including the power to borrow money for company purposes.
Changes
in Capital
The
Company’s amended and restated articles of association enable us to increase or reduce our share capital. Any such changes are
subject to the provisions of the Companies Law and must be approved by a resolution duly adopted by our shareholders at a general meeting.
In addition, transactions that have the effect of reducing capital, such as the declaration and payment of dividends in the absence of
sufficient retained earnings or profits, require the approval of both our board of directors and an Israeli court.
Establishment
We
were incorporated under the laws of the State of Israel on February 13, 2017. We are registered with the IRC.
Exclusive
Forum
The
Company’s amended and restated articles of association to be effective immediately prior to the closing of this offering provide
that unless we consent in writing to the selection of an alternative forum, the federal district courts of the United States shall
be the exclusive forum for the resolution of any complaint asserting a cause of action arising under the Securities Act. This choice
of forum provision may limit a shareholder’s ability to bring a claim in a judicial forum that it finds favorable for disputes
with us or our directors, officers or other employees and may increase the costs associated with such lawsuits, which may discourage
such lawsuits against us and our directors, officers and employees.
This
exclusive forum provision would not apply to claims brought pursuant to the Securities Act or the Exchange Act or any other claim
for which U.S. federal courts would have exclusive jurisdiction. To the extent that any such claims may be based upon federal law
claims, Section 27 of the Exchange Act creates exclusive federal jurisdiction over all suits brought to enforce any duty or
liability created by the Exchange Act or the rules and regulations thereunder.
Alternatively,
if a court were to find these provisions of the Company’s amended and restated articles of association to be effective immediately
prior to the closing of this offering inapplicable to, or unenforceable in respect of, one or more of the specified types of actions
or proceedings, we may incur additional costs associated with resolving such matters in other jurisdictions, which could adversely affect
our business and financial condition.
The
Company’s amended and restated articles of association to be effective immediately prior to the closing of this offering also provide
that unless we consent in writing to the selection of an alternative forum, the competent courts in Tel Aviv, Israel shall be the exclusive
forum for any derivative action or proceeding brought on behalf of the Company, any action asserting a breach of a fiduciary duty owed
by any of our directors, officers or other employees to the Company or our shareholders or any action asserting a claim arising pursuant
to any provision of the Companies Law or the Israeli Securities Law.
Any
person or entity purchasing or otherwise acquiring any interest in our share capital shall be deemed to have notice of and to have consented
to these choice of forum provisions.
History
of Share Capital
Since
January 1, 2020, our issued share capital has changed as provided below.
On
February 18, 2020, we entered into a crowd-funding transaction in which we issued 370,356 ordinary shares to 536 different
investors for total net consideration of $447 thousand (net of $52 thousand issuance cost).
On
April 26 2020, we entered into another crowd-funding transaction in which we issued 47,688 shares to 161 different investors for
total net consideration of $61 thousand (net of $8 thousand issuance cost).
In
February, May, June and July 2021, we entered into Simple Agreements for Future Equity (each, a “SAFE”) with four separate
investors for aggregate proceeds of $800 thousand. Pursuant to the terms of each SAFE, upon consummation of an equity financing, we were
required to issue to each investor the number of ordinary shares equal to the purchase amount divided by the SAFE price, which was defined
as the price per share equal to 80% of the equity financing valuation (to be no less than $25,000 thousand). The SAFE Agreements also
provide the investor the right to automatically receive ordinary shares in the case of a liquidity event, defined as a change of control
event or an initial public offering. In the case of a liquidity event the investors are entitled to the number of ordinary shares equal
to the investment amount divided by the liquidity price. The liquidity price is defined as the price per share equal to the Company’s
valuation at the time of the liquidity event, multiplied by 80%, and divided by the Company’s capitalization (to be no less than
$25,000 thousand). As part of our initial public offering, the SAFEs were converted at a price per share of $2.892 into 276,672 ordinary
shares.
In
May and October 2021, we issued 240,000 and 45,000 ordinary shares, respectively, pursuant to the exercise of options at an
exercise price of $0.033 per share.
In
August and September 2021, we issued 1,837,500 ordinary shares pursuant to the exercise of warrants at a weighted average price
of $0.67 per share.
On
November 9, 2021, we implemented a 1-for-3 split of our share capital, resulting in an increase of the issued and outstanding ordinary
shares.
On
December 13, 2021, we completed our initial public offering and issued 2,000,000 units, each consisting of one ordinary share
and a warrant representing the right to purchase one ordinary share with an exercise price of $6.00 per share, at an initial public offering
price of $6.00 per unit. We also issued Warrants to purchase an additional 300,000 ordinary shares at an exercise price of $6.00 per
share upon exercise by the underwriter of their overallotment option.
In
connection with the closing of our initial public offering, on December 13, 2021, we issued 961,440 ordinary shares pursuant
to the exercise of options at a weighted average exercise price of $0.079 per share.
In
March 2022, we issued 645,000 ordinary shares upon exercise of warrants issued in our initial public offering at a price per
share of $6.00.
In
October 2022, we issued 35,980 ordinary shares pursuant to vesting of restricted stock units (“RSUs”) that were
granted to one of our officers in October 2021.
In
December 2022, we issued 72,000 ordinary shares pursuant to vesting of RSUs that were granted to our officers in November 2021.
In
2022, we issued 85,449 ordinary shares to certain consultants in exchange for their services. One of the consultants received 44,000
shares of restricted stock which were issued in 4 equal installments and subject to 2 year lock-up period. The other consultant’s
received ordinary shares subject to a 6 month lock-up.
In
March, June and September 2023, we issued 54,000 ordinary shares pursuant to vesting of RSUs that were granted to our officers
in November 2021.
In
May 2023, we issued 3,600 ordinary shares for gross proceeds of $7,200 in connection with our at-the-market offering program.
The ordinary Shares were sold at market prices at the time of sale.
In
May and June we issued 320,479 ordinary shares pursuant to vesting of RSUs that were granted to our officers in March 2023.
In
June and September2023, we issued 50,000 ordinary shares pursuant to vesting of RSUs that were granted to our employees in March 2023.
In
June 2023, we issued 126,000 ordinary shares pursuant to the exercise of options at an exercise price of $0.033 per share.
In
June 2023, we issued 1,330,000 ordinary shares pursuant to a registered direct offering at a price per share of $1.50.
Transfer
Agent and Registrar of ordinary shares
The
transfer agent and registrar for the ordinary shares American Stock Transfer & Trust Company, LLC. Its address is 6201 15th Avenue,
Brooklyn, New York 11219, and its telephone number is (800) 937-5449.
PLAN
OF DISTRIBUTION
The
ongoing offer and sale by us of the ordinary shares issuable upon exercise of the Warrants is being made pursuant to this prospectus.
We
will deliver ordinary shares upon exercise of the Warrants, in whole or in part. We will not issue fractional ordinary shares. Each Warrant
contains instructions for the exercise. In order to exercise a Warrant, the holder must deliver the information required by the applicable
warrant agreement, along with payment of the exercise price, if the exercise price is being paid in cash, for the ordinary shares to
be purchased. We will then deliver our ordinary shares in the manner described in the applicable warrant agreement.
Offer
Restrictions Outside the United States
Other
than in the United States, no action has been taken by us that would permit a public offering of the securities offered by this prospectus
in any jurisdiction where action for that purpose is required. The securities offered by this prospectus may not be offered or sold,
directly or indirectly, nor may this prospectus or any other offering material or advertisements in connection with the offer and sale
of any such securities be distributed or published in any jurisdiction, except under circumstances that will result in compliance with
the applicable rules and regulations of that jurisdiction. Persons into whose possession this prospectus comes are advised to inform
themselves about and to observe any restrictions relating to the offering and the distribution of this prospectus. This prospectus does
not constitute an offer to sell or a solicitation of an offer to buy any securities offered by this prospectus in any jurisdiction in
which such an offer or a solicitation is unlawful.
LEGAL
MATTERS
The
validity of our ordinary shares offered by this prospectus relating to Israeli law will be passed upon for us by Goldfarb Gross Seligman
& Co., Israel. Certain members of Goldfarb Gross Seligman & Co. are the beneficial owners of an aggregate of less than 1.0% of
our ordinary shares.
EXPERTS
The
consolidated financial statements of NeuroSense Therapeutics Ltd. as of December 31, 2022 and 2021 and for each of the years in the three-year
period ended December 31, 2022 have been incorporated by reference herein in reliance upon the report of Somekh Chaikin, a member firm
of KPMG International, independent registered public accounting firm, incorporated by reference herein, and upon the authority of said
firm as experts in accounting and auditing. The audit report covering the December 31, 2022 consolidated financial statements contains
an explanatory paragraph that states that the Company’s recurring losses and its expectation to incur significant additional losses
raise substantial doubt about the entity’s ability to continue as a going concern. The consolidated financial statements do not
include any adjustments that might result from the outcome of that uncertainty.
WHERE
YOU CAN FIND MORE INFORMATION
This
prospectus is part of the registration statement on Form F-1 we filed with the SEC under the Securities Act, with respect to the securities
offered by this prospectus. However, as is permitted by the rules and regulations of the SEC, this prospectus, which is part of our registration
statement on Form F-1, omits certain non-material information, exhibits, schedules and undertakings set forth in the registration statement.
For further information about us, and the securities offered by this prospectus, please refer to the registration statement and the exhibits
and schedules filed as a part of the registration statement. You should rely only on the information contained in this prospectus or
incorporated by reference. We have not authorized anyone else to provide you with different information. We are not making an offer of
these securities in any state where the offer is not permitted.
We
are subject to the reporting requirements of the Exchange Act that are applicable to a foreign private issuer. In accordance with the
Exchange Act, we file reports, including annual reports on Form 20-F by April 30 of each year. We also furnish to the SEC under cover
of Form 6-K material information required to be made public in Israel, filed with and made public by any stock exchange or distributed
by us to our shareholders.
The
SEC maintains an Internet site that contains reports, proxy and information statements, and other information regarding issuers, such
as us, that file electronically with the SEC (http://www.sec.gov).
As
a foreign private issuer, we are exempt from the rules under the Exchange Act prescribing the furnishing and content of proxy statements
to shareholders and our officers, directors and principal shareholders are exempt from the “short-swing profits” reporting
and liability provisions contained in Section 16 of the Exchange Act and related Exchange Act rules.
INCORPORATION
OF CERTAIN DOCUMENTS BY REFERENCE
We
file annual and special reports and other information with the SEC (File Number 001-41084). These filings contain important information
which does not appear in this prospectus. The SEC allows us to “incorporate by reference” information into this prospectus,
which means that we can disclose important information to you by referring you to other documents which we have filed with the SEC. We
are incorporating by reference in this prospectus the documents listed below:
|
● |
our Annual Report on Form 20-F for the fiscal year ended on December 31, 2022, filed with the SEC on March 22, 2023; and |
|
● |
our reports on Form 6-K
furnished to the SEC on April 14, 2023, April 17, 2023 (with respect to Exhibit 99.1, all of the text other than the paragraph immediately
preceding the heading “About NeuroSense”), May 2, 2023 (with respect to Exhibit 99.1, all of the text other than the
three paragraphs immediately preceding the heading “About Parkinson’s Disease”), May 15, 2023 (with respect to
Exhibit 99.1, all of the text other than the three paragraphs immediately preceding the heading “About ALS”), May 25, 2023, May 31, 2023, June 1, 2023 (with respect to Exhibit 99.1, all of the text other than the paragraph immediately preceding the
heading “Business Update”), June 13, 2023, June 23, 2023, July 6, 2023 (with respect to Exhibit 99.1, all of the text
other than the paragraph immediately preceding the heading “About NeuroSense”), August 16, 2023 (with respect to Exhibit 99.1, only the text under the headings “Financial Summary” and “Forward-Looking Statements”), September 19, 2023 (other than the paragraph immediately preceding the heading “About NeuroSense” in Exhibit 99.1), September 20, 2023
(with respect to Exhibit 99.1, all of the text other than the paragraph immediately preceding the heading “About NeuroSense”),
September 29, 2023, October 2, 2023 (with respect to Exhibit 99.1, only the first paragraph), October 4, 2023 (with respect to Exhibit 99.1, only the first three paragraphs), October 17, 2023 (with respect to Exhibit 99.1, all of the text other than the paragraph
immediately preceding the heading “About NeuroSense”), November 6, 2023 (with respect to Exhibit 99.1, all of the text
other than for the two paragraphs immediately preceding the heading “About ALS”), November 13, 2023 (with respect to
Exhibit 99.1, all of the text other than for the second paragraph), November 28, 2023 (with respect to Exhibit 99.1, all of the text
other than the second paragraph) and our report on Form 6-K/A furnished to the SEC on
January 19, 2023 (with respect to Exhibit 99.1, only the text under the headings “Business Update” (first two paragraphs),
“Financial Summary”, “Forward-Looking Statements” and financial tables); and |
|
|
|
|
● |
the description of the
ordinary shares contained under the heading “Item 1. Description of Registrant’s Securities to be Registered” in
our registration statement on Form 8-A, as filed with the SEC on November 18, 2021, including any subsequent amendment or any report
filed for the purpose of updating such description. |
Certain
statements in and portions of this prospectus update and replace information in the above listed documents incorporated by reference.
We
will provide each person, including any beneficial owner to whom a prospectus is delivered, without charge, upon a written or oral request,
a copy of any of the documents incorporated by reference in this prospectus, other than exhibits to such documents which are not specifically
incorporated by reference into such documents. Please direct your written or telephone requests to NeuroSense Therapeutics Ltd., 11 HaMenofim
Street, Building B, Herzliya, 4672562, Israel, Attn: Or Eisenberg, telephone number +972587531153. You may also obtain information about
us by visiting our website at www.neurosense-tx.com. Information contained in our website is not part of this prospectus.
SERVICE
OF PROCESS AND ENFORCEMENT OF CIVIL LIABILITIES
We
are incorporated under the laws of the State of Israel. Service of process upon us and upon our directors and officers and the Israeli
experts named in this prospectus, substantially all of whom reside outside the United States, may be difficult to obtain within the United
States. Furthermore, because substantially all of our assets and substantially all of our directors and officers are located outside
the United States, any judgment obtained in the United States against us or any of our directors and officers may not be collectible
within the United States.
We
have irrevocably appointed Cogency Global Inc. as our agent to receive service of process in any action against us in any U.S. federal
or state court arising out of this offering or any purchase or sale of securities in connection with this offering. The address of our
agent is 122 East 42nd Street, 18th Floor, New York, NY 10168.
We
have been informed by our legal counsel in Israel, Goldfarb Gross Seligman & Co., that it may be difficult to initiate an action
with respect to U.S. securities law in Israel. Israeli courts may refuse to hear a claim based on an alleged violation of U.S. securities
laws reasoning that Israel is not the most appropriate forum to hear such a claim. In addition, even if an Israeli court agrees to hear
a claim, it may determine that Israeli law and not U.S. law is applicable to the claim. If U.S. law is found to be applicable, the content
of applicable U.S. law must be proved as a fact by expert witnesses which can be a time-consuming and costly process. Certain matters
of procedure may also be governed by Israeli law.
Subject
to certain time limitations and legal procedures, Israeli courts may enforce a U.S. judgment in a civil matter which, subject to certain
exceptions, is non-appealable, including judgments based upon the civil liability provisions of the Securities Act and the Exchange Act
and including a monetary or compensatory judgment in a non-civil matter, provided that:
|
● |
the judgment was rendered
by a court which was, according to the laws of the state of the court, competent to render the judgment; |
|
● |
the obligation imposed
by the judgment is enforceable according to the rules relating to the enforceability of judgments in Israel and the substance of
the judgment is not contrary to public policy; and |
|
● |
the judgment is executory
in the state in which it was given. |
Even
if these conditions are met, an Israeli court will not declare a foreign civil judgment enforceable if:
|
● |
the judgment was given
in a state whose laws do not provide for the enforcement of judgments of Israeli courts (subject to exceptional cases); |
|
● |
the enforcement of the
judgment is likely to prejudice the sovereignty or security of the State of Israel; |
|
● |
the judgment was obtained
by fraud; |
|
● |
the opportunity given to
the defendant to bring its arguments and evidence before the court was not reasonable in the opinion of the Israeli court; |
|
● |
the judgment was rendered
by a court not competent to render it according to the laws of private international law as they apply in Israel; |
|
● |
the judgment is contradictory
to another judgment that was given in the same matter between the same parties and that is still valid; or |
|
● |
at the time the action
was brought in the foreign court, a lawsuit in the same matter and between the same parties was pending before a court or tribunal
in Israel. |
If
a foreign judgment is enforced by an Israeli court, it generally will be payable in Israeli currency, which can then be converted into
non-Israeli currency and transferred out of Israel. The usual practice in an action before an Israeli court to recover an amount in a
non-Israeli currency is for the Israeli court to issue a judgment for the equivalent amount in Israeli currency at the rate of exchange
in force on the date of the judgment, but the judgment debtor may make payment in foreign currency. Pending collection, the amount of
the judgment of an Israeli court stated in Israeli currency ordinarily will be linked to the Israeli consumer price index plus interest
at the annual statutory rate set by Israeli regulations prevailing at the time. Judgment creditors must bear the risk of unfavorable
exchange rates.
Up
to 1,755,000 Ordinary Shares Underlying Warrants
Prospectus
December
4, 2023
NeuroSense Therapeutics (NASDAQ:NRSN)
過去 株価チャート
から 12 2024 まで 1 2025
NeuroSense Therapeutics (NASDAQ:NRSN)
過去 株価チャート
から 1 2024 まで 1 2025