AVAX Technologies Appoints Dr. Francois Martelet to Its Board of Directors
2007年7月26日 - 9:28AM
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AVAX Technologies, Inc. (OTCMarket: AVXT.OB) announced today that
Dr. Fran�ois Martelet has been appointed as a director on the
Company�s Board of Directors (the �Board�), effective as of July
20, 2007. Dr. Martelet is a senior pharmaceutical executive and
brings to AVAX over 16 years of international experience. Most
recently, he served as Vice-President and Global Franchise Head,
Oncology with Merck & Co. Prior to that, Dr. Martelet was the
Regional Pharmaceutical Head, Central & Eastern Europe, Middle
East and Africa for Novartis Pharma AG, in addition served in
various senior officer positions within units of Novartis
Pharmaceuticals, including leading the Oncology Business Units in
Asia, Latin America, Central and Eastern Europe, the Middle East
and Africa. �Fran�ois� extensive expertise gained at the corporate
and operational level in oncology product and pipeline development,
marketing and distribution activities together with his strong
background in Europe will be invaluable in driving AVAX�s strategy
and development activities,� stated John Prendergast, Executive
Chairman of AVAX. �We welcome him to the Board and look forward to
his participation at AVAX.� Prior to joining Novartis, Dr. Martelet
served in various oncology-related capacities with Schering-Plough
International, Eli Lilly Corporation and F. Hoffman-la Roche, AG.
Dr. Martelet is presently providing consulting services for MedNest
LLC, The Gerson Lerhman Group LLC, and Greenwood Research LLC,
which provide business development and operational consulting
services to medical technology, pharmaceutical, biotechnology and
health care service providers. Dr. Martelet received a Doctorate in
Medicine with distinction and a Pharmaceutical Marketing Master's
Degree in Business from Dijon University, France. He also holds a
degree in Legal Medicine from R. Descartes University School of
Medicine, Paris. Richard Rainey, President & Chief Executive
Officer of AVAX noted, �In addition to providing input on the
execution of our Phase III registration trial for M-Vax� which is
beginning in the US, Europe and Israel, we will look forward to
Fran�ois� involvement in developing our existing commercial
opportunities in Europe.� M-Vax, the AC Vaccine candidate for
melanoma, is currently authorized by the Swiss Federal Office of
Public Health (FOPH) for the import and export of the product in
accordance with the law for Control of Transplantation (SR 818.111)
passed in March 1996. In addition, M-Vax has been made available on
a compassionate use basis in various jurisdictions throughout
Europe. About AVAX Technologies, Inc. AVAX Technologies, Inc. is a
biotechnology company with operations in the United States and
Europe. The Company is engaged in the research, clinical and
commercial development of biological products and cancer
therapeutics. AVAX�s AC Vaccine platform is a therapeutic cancer
vaccine. In addition, the Company performs contract-manufacturing
services for biological products for other pharmaceutical and
biotechnology companies. AVAX�s lead clinical program is its Phase
III study of M-Vax, the AC Vaccine designed for the treatment of
malignant melanoma. The study design was approved as part of a
Special Protocol Assessment agreement with the FDA. M-Vax, and
other AC Vaccines, are prepared by attaching a small molecular
weight chemical to the patient�s tumor cells by a process known as
haptenization. This chemical modification of the tumor cells makes
them visible to the patients� immune system, which allows them to
stimulate a T cell-based immune response. Initially, the immune
response is directed to the hapten-modified cells, which may be
followed by a T cell response to the native, unmodified melanoma
cells. In a paper published in International Journal of Cancer, it
was shown that M-Vax induced tumor shrinkage in 11/83 patients with
surgically incurable stage IV melanoma. In a subsequent paper in a
peer-reviewed journal by another clinician who treated patients
with their DNP modified tumor cells, using techniques similar to
M-Vax, followed by administration of low dose interleukin-2, a
response rate of 35% was observed. These results are supported by a
paper published in the Journal of Clinical Oncology, February 2004,
which reported immunological and clinical outcomes for 214 patients
with clinically evident Stage III melanoma treated with M-Vax
following surgery. The five-year survival of these high risk
patients was 45%, compared with the 20-25% reported in many studies
using surgery alone. Moreover, there was a highly statistically
significant relationship between overall survival and the
development of DTH to patients� own tumor cells following M-Vax
administration. Except for statements that are historical, the
statements in this release are "forward-looking" statements that
are made pursuant to the safe harbor provisions of Section 27A of
the Securities Act of 1933 and Section 21E of the Securities
Exchange Act of 1934. Forward-looking statements involve
significant risks and uncertainties, and in light of the
significant uncertainties inherent in such statements, the
inclusion of such information should not be regarded as a
representation by AVAX that the objectives and plans of the Company
will be achieved. In fact, actual results could differ materially
from those contemplated by such forward-looking statements. Many
important factors affect the Company's prospects, including (1) the
need to obtain additional funding (beyond the proceeds of the April
2007 private offering) in the future to continue to finance the
Company�s development plans, (2) the results of clinical and
laboratory testing of its vaccine technologies, (3) possible future
FDA or AFSSAPS questions regarding the Company's products and
manufacturing processes, (4) exchange rate risks associated with
financing the Company in U.S. dollars but funding significant
operating expenses in Europe with Euro�s, (5) the Company's ability
to maintain its rights under license agreements and to meet funding
requirements under its license agreements, (6) the Company's
ability to demonstrate the safety and efficacy of product
candidates at each stage of development and to meet applicable
regulatory standards and receive required regulatory approvals, as
well as other risks detailed from time to time in AVAX's public
disclosure filings with the Securities and Exchange Commission,
including its Annual Report on Form 10-KSB for the year ended
December 31, 2006. AVAX does not undertake any obligation to
release publicly any revisions to these forward-looking statements
or to reflect the occurrence of unanticipated events.
AVAX Technologies (CE) (USOTC:AVXT)
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AVAX Technologies (CE) (USOTC:AVXT)
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