ActivePure Medical Publishes Definitive Safety Study of Its Advanced Photohydrolysis Technology
2024年10月10日 - 3:00AM
ビジネスワイヤ(英語)
Comprehensive murine study confirms safety,
complementing previous efficacy data on ActivePure’s continuous air
and surface decontamination technology
ActivePure Medical, a division of AP Sciences Group, LLC, a
global provider of cutting-edge, continuous air and surface
decontamination technology, today announced results from a safety
study of its ActivePure Advanced Photohydrolysis Technology. The
study, published in PLOS One, provides direct and comprehensive
evidence of the safety of ActivePure’s proprietary photohydrolysis
technology, for use in occupied indoor spaces.1 These findings
support and encourage the continued adoption of this proven
technology for reducing airborne and surface pathogens.
There is a pressing need for effective, continuous air cleaning
and surface disinfection technologies, highlighted by recent public
health crises. ActivePure Technology, as implemented in the Induct
Guardian Series, has already demonstrated significant efficacy in
reducing pathogens with a recent study published in the American
Journal of Infection Control showing 96-99% reduction in
methicillin-resistant Staphylococcus aureus (MRSA) and 70-71%
decreases in healthcare-associated infections in hospital settings
over 12-21 months.2
This newly published data complements previous efficacy studies
by demonstrating the safety of continuous use of the ActivePure
Advanced Photohydrolysis Technology. The study utilized murine
subjects due to their physiological similarities to humans. The
90-day safety study used a C57BL murine model, a strain chosen for
its sensitivity to airborne substances and pronounced inflammatory
responses. The mice were exposed to therapeutic levels of
ActivePure’s Advanced Photohydrolysis Technology, with researchers
monitoring behavior, weight gain, food consumption, blood chemistry
and hematology, as well as conducting detailed histological
examinations of respiratory tissues.
“This study provides detailed, direct evidence of the safety of
advanced photohydrolysis technology using a mammalian model,” said
Claude P. Selitrennikoff, Ph.D., the lead study author. “Thorough
examination of respiratory tissues revealed no adverse effects on
physiology, even after continuous 90-day exposure. In an era marked
by emerging global health threats, innovations like ActivePure
Advanced Photohydrolysis Technology are essential for creating
safer indoor environments.”
Key findings include:
- No observable differences in behavior, weight gain, or food
consumption between exposed and control mice
- Normal blood chemistry and hematology values in exposed
mice
- No evidence of tissue damage, inflammation, or abnormalities in
the respiratory tract of exposed mice
“ActivePure Technology has established through FDA clearance,
lab testing, and real-world outcomes, that it is highly effective
at remediating the six most infectious forms of pathogens,” said
Joseph, P. Urso, CEO of AP Sciences Group, LLC. “The results of
this research study bring further assurance to questions of safety
that should be asked regarding every technology being used to
protect health. We are delighted to share this study and build
confidence, not only in the efficacy of ActivePure, but also in the
peace of mind that can come from its implementation.”
About ActivePure Medical
ActivePure Medical, a division of AP Sciences Group, LLC, is a
global leader in proactive, continuous surface and air
decontamination systems for healthcare. The company's proprietary
ActivePure Advanced Photohydrolysis Technology safely neutralizes
indoor contaminants in the air and on surfaces. This scientifically
adapted technology replicates the natural atmospheric cleansing
processes, providing continuous, persistent protection against
environmental contamination risks without relying on human
intervention. ActivePure Technology effectively reduces many common
volatile organic compounds (VOCs) and operates without producing
harmful ozone, making it safe for continuous use in occupied
spaces. Initially developed for space exploration, it has evolved
to reduce exposure to pathogens, including RNA and DNA viruses,
bacteria, and molds, by up to 99.9% in the air and on surfaces.
ActivePure Technology has proven effective across various settings,
including acute care, long-term care facilities, and commercial
buildings. ActivePure Technology is a key component in the
ActivePure Medical Guardian, an FDA 510(k)-cleared Class II Medical
Device. For more information, please visit
ActivePure.com/healthcare.
About ActivePure Advanced Photohydrolysis Technology
ActivePure Technology is a pioneering approach to environmental
decontamination. The technology features a honeycomb matrix with a
proprietary coating and a specialized UV bulb, facilitating a
photolysis reaction with ambient humidity, which produces powerful
hydrogen and oxygen-based oxidative molecules, effective at
remediating a broad spectrum of contaminants. This proactive
process targets both air and surface contamination, providing
continuous, 24/7 protection. Studies have confirmed its efficacy,
demonstrating up to 99% reduction in surface methicillin-resistant
Staphylococcus aureus (MRSA) and fungi, and significant decreases
in healthcare-associated infections (HAIs).
__________________________ 1 Selitrennikoff CP, et al. (2024)
Evaluate the safety of a novel photohydrolysis technology used to
clean and disinfect indoor air: A murine study. PLoS ONE.
19(10):e0307031. doi.10.1371/journal.pone.0307031
2 Trosch, K et al. (2024) The effects of a novel, continuous
disinfectant technology on methicillin-resistant Staphylococcus
aureus (MRSA), fungi, and aerobic bacteria in 2 separate intensive
care units in 2 different states: An experimental design with
observed impact on health care associated infections (HAIs). Am. J.
Infect. Control. 52(8):884-892. doi:10.1016/j.ajic.2024.03.013
View source
version on businesswire.com: https://www.businesswire.com/news/home/20241009073368/en/
Media: Ben Shannon ICR Westwicke
ActivePurePR@westwicke.com