Pfizer Inc (PFE) オプション

Pfizer’s Pipeline Pruning Ends Early-Stage STING Trial

https://www.biospace.com/business/pfizers-pipeline-pruning-ends-early-stage-sting-trial

https://annualreview.pfizer.com/

In 2024, we returned $9.5 billion to shareholders via our quarterly dividend, invested $10.8 billion in internal R&D and paid down approximately $7.8 billion of debt.

well yes it will be interesting to see what happens here and may be a hint as to who is in control. Thanks for that info.

Analysts at Evercore ISI said today’s readout would be “likely sufficient for approval in ESR1m patients, but not dramatic.”

let's see what happens------

I saw-----

The magnitude of PFS improvement in patients with the ESR1 mutation with vepdegestrant “exceeded the pre-specified target” of a 40% reduction in the risk of death or disease progression, according to the release, though Pfizer and Arvinas did not provide a more specific figure for their drug candidate.

Data for overall survival had not yet matured at the time of data collection, according to the companies’ news release. VERITAC-2 will continue to follow patients to assess this outcome, one of its key secondary endpoints.

https://www.biospace.com/drug-development/pfizer-arvinas-post-mixed-late-stage-breast-cancer-data-for-closely-watched-protac-drug

I was waiting on that. Not good for Pfizzi. They no longer get a free ride into approvals.
Look see here. https://www.fiercebiotech.com/biotech/pfizer-arvinas-hormone-therapy-posts-mixed-survival-results-first-phase-3-test?oly_enc_id=4924G0643390I0A

With new health agency watchdogs, things are going to get tougher for them.
The playing field is leveling. Something they never encountered before.

Those results weren't actually positive insofar as the primary endpoint was missed. That's why PFE's partner, ARVN is down 52% today.

announced positive topline results from the Phase 3 VERITAC-2 trial, where vepdegestrant monotherapy met the primary endpoint in ER+/HER2- breast cancer patients with estrogen receptor 1 mutations, showing significant and clinically meaningful improvement in progression-free survival. This marks the first pivotal data for vepdegestrant, a potential first-in-class oral PROTAC ER degrader.

Breakout now confirmed..

If prescription drugs cured

There would be no need

For pharmaceutical companies

ANTI-VAXXERS AGHAST AS RFK JR. ADMITS THAT VACCINES ARE PRETTY FANTASTIC

is written on the wall---------

https://futurism.com/neoscope/anti-vaxxers-aghast-rfk-jr-vaccines

Possible second measles death in US, New Mexico officials say. Both deaths unvaccinated

https://eu.usatoday.com/story/news/health/2025/03/06/second-measles-death-new-mexico-outbreak/81806503007/

BioNTech and Pfizer must pay damages to Moderna for the use of one of its patents in Germany.

https://www.juve-patent.com/cases/moderna-and-freshfields-triumph-in-dusseldorf-against-biontech-and-pfizer/

Natural immunity from measles is lifelong

While vaccines push endless boosters

Trust your immune system

Not the pharma-driven panic

~ Dr Sherri Tenpenny ~


Before the measles vaccine

We had the Brady Bunch

Telling it like it is


Fear mongering = vaccine push

Must keep those dollars rolling

From the uneducated

Must feel good

About that

RFK Jr. Acknowledges the Measles Vaccine: -history repeats itself-
In 2000, the CDC declared that measles had been eliminated from the United States. But now America is at risk of losing that status: A measles outbreak has sickened more than 150 people in Texas and New Mexico since late January. An unvaccinated school-aged child recently died from measles in Texas.

Measles is arguably the most contagious infectious disease that scientists know about. Researchers have estimated that, in a population where there’s zero immunity to measles, one infected person is going to infect roughly 12 to 18 other people. That is extremely high.

The MMR vaccine, which protects against measles, mumps, and rubella, generally provides immunity from measles for decades. But there are kids who are not old enough to be fully vaccinated against measles (kids get one shot at 12 to 15 months and then again at 4 to 6 years old)

Vaccines not only protect individual children from measles, but also contribute to community immunity, protecting those who are unable to be vaccinated due to medical reasons.

Having faith in RFK Jr.

Despite the deep pharma infiltration of HHS

Brady Bunch on measles

Natural immunity is lifelong

While vaccines push endless boosters

Trust your immune system

Not the pharma-driven panic

~ Dr Sherri Tenpenny ~

"history repeats itself" Many in the anti-vax community turned on Robert F. Kennedy Jr. Monday after President Donald Trump’s health secretary penned a column endorsing the vaccination of children against measles.


https://www.thedailybeast.com/rfk-jr-spokesman-tom-corry-quits-and-anti-vaxxers-furious-over-flip-flop/

Yes, and for the better finally. Been a long time coming.

Momrow, the world has moved foward..

So you support a company that lies and kills. Your choice. But not my kind of guy.
However, things are getting sterilized: https://dailypresser.com/david/former-nih-director-francis-collins-retires-amid-controversy-over-alleged-involvement-in-wuhan-lab-research/

Hammer will fall.

https://pfizersxswpodcastinglounge.my.canva.site/?linkId=763415080

-clown- RFK Jr urges Americans to get vaccinated amid measles outbreak: ‘A call to action’

https://www.hindustantimes.com/world-news/us-news/rfk-jr-urges-americans-to-get-vaccinated-amid-measles-outbreak-a-call-to-action-101740995866989.html

But they pay dividends! 

Liability or no liability. The people of the world are reacting to the lies. Pfizer/Moderna will pay for their deceit and all those who assisted in this human assault whether they were part of it originally or just taking the money or to maintain their jobs.

FOCAL POINTS (Courageous Discourse) cross-posted a post from Truth, Investing, and Freedom

Peter A. McCullough, MD, MPHMar 2 · FOCAL POINTS (Courageous Discourse)

Colleagues

Please see this important release on toxic vaccine lots in Canada and the coverup by British Columbia officials as Dr Hoffe and others worked to expose the problem.

Peter A. McCullough, MD, MPH
Review of FOI F23-1799 and BC Public Health’s Handling of COVID-19 Vaccines AEFI – Part 1
Lex Acker
Mar 2






READ IN APP

Background

In April 2023, Lee Turner, of Doak Shireff Lawyers LLP, took over conduct of the defence of Dr. Charles Hoffe vs. the College of Physicians and Surgeons of BC. Mr. Turner subsequently filed a Freedom of Information (FOI) request (F23-1799) with the Provincial Health Services Authority (PHSA) to obtain data on Adverse Events Following Immunization (AEFI). FOI F23-1799 can be accessed at this link.

FOI F23-1799 was released in June 2024 and comprised over 1,300 pages of internal emails between BC CDC staff, Bonnie Henry, Reka Gustafson, and Monika Naus (then head of BC CDC), along with dozens of AEFI reports.

Upon reviewing FOI F23-1799, I noted key elements: discussions of AEFIs in emails, screenshots of non-public AEFI reports available through an intranet, and public-facing AEFI reports presented in chronological order. This arrangement made it possible to determine what BC public health officials like Bonnie Henry, the BC CDC and all 50+ medical health officers scattered over BC health authorities knew and when they knew it.

I reached an unsettling conclusion: BC CDC had manipulated the definition of Serious Adverse Events Following Immunization to lower the reported rates of Serious AEFIs in public-facing reports, thereby concealing the true risks associated with COVID-19 vaccines. I publicly shared this finding on June 14, 2024, in a comment on Byram Bridle’s post titled Breaking News: BC Centre for Disease Control Caught Lying and Withholding Important Public Health Data.

While my expertise is not in medical science, I specialize in detecting and documenting corporate and institutional misconduct. My background is in financial statement analysis. I worked as a hedge fund research analyst and compliance officer for a boutique investment firm. I have about 15 years of independent financial research and analysis experience. My focus is uncovering white-collar fraud. I’m not a forensic accountant by any measure; I’m just someone with somewhat odd proclivities for large sets of unstructured data and enjoy immersing myself in new topics.
The Case Against Dr. Hoffe

The College of Physicians and Surgeons of BC cancelled its February 11, 2022 citation against Dr. Hoffe on February 5, 2025. According to one media outlet, this was done because of a "material change of circumstances."

The College accused Dr. Hoffe of professional misconduct; specifically spreading misinformation about COVID-19 vaccines. Here’s an excerpt of the College’s accusations:

“… publicly expressing that the COVID-19 vaccinations cause microscopic blood clots that cause serious neurological harm, female infertility, and a high number of deaths that is not recognized by public health; …”

Many other doctors were publicly denouncing the COVID-19 vaccines and were persecuted by the College. However, the level of persecution against Dr. Charles Hoffe is particular. The College retained eight experts against Dr. Hoffe. Why is that?

In early 2021, Dr. Hoffe submitted a temporally- and vaccine lot-associated cluster of 11 AEFI reports to Interior Health, 10 of which involved Moderna lot #300042698, administered between January 18 and February 5, 2021.



As Dr. Hoffe began filing AEFI reports in early 2021—most notably in April and May— and went on public tours in BC warning the public about the harms of COVID-19 vaccines his actions posed a direct threat to a state narrative that sought to suppress information about vaccine-related harm. His findings challenged the political and ideological foundation underpinning the mass vaccination program and the totalitarian controls over the population that came along with it.

The evidence in FOI F23-1799 suggests that Bonnie Henry, the BC CDC, all health authorities, and all 50+ Medical Health Officers in BC were fully aware of these issues. Dr. Hoffe’s real "offence" was exposing what the BC government concealed from the public since early 2021. Dr. Hoffe’s AEFI reports constituted a cluster of AEFI associated with unexpected harms which required public health authorities to investigate and disclose to the public.

This post, and a few more to come, will cover my findings and analysis of how BC public authorities handled the COVID-19 vaccine AEFIs.
BC Public Health Officials Early Knowledge of Harms Associated with the COVID-19 Vaccines
Higher AEFI Rates Associated with Higher mRNA Content

January 28th, 2021 - P. 18, FOI F23-1799:



Above, is the upper half of an email to Bonnie Henry where Monika Naus, Medical Director of the BC CDC, states: “A history of anaphylaxis to a dose of the vaccine is a contraindication to receipt of future doses.” This is important to keep in mind as I will relate that statement to data in non-public AEFI reports further down.

Monika Naus, briefed Bonnie Henry and Martin Lavoie, Chief Medical Health Officer of Interior Health, on the observation that ‘cellulitis’ events occurred at “an appreciably higher rate” with the Moderna vaccine compared to Pfizer. However, she seems to downplay the significance of these reported cases.

Monika Naus explained that the higher rate of AEFIs associated with Moderna was consistent with its higher mRNA content. Her statements indicate an awareness that, since Pfizer and Moderna vaccines share similar structures, the key difference lies in mRNA dosage. Below is the lower half of Monika Naus’ email to Bonnie Henry.



Above, Monika Naus reports to Bonnie Henry the death of an inmate and two temporally associated thrombocytopenia reports. A few months later, the BC CDC will deny in public-facing AEFI reports that they received thrombocytopenia cases. Monika Naus stresses with capital letters that this is NOT being seen in the US analytic data comparing rates, indicating that she’s worried and that these findings in BC were unexpected. The link at the bottom of the above email is to slide deck containing V-Safe data.
Misleading Public Reporting of Thrombocytopenia and Serious AEFIs

In the above email of January 28th, 2021 to Bonnie Henry, Monika Naus refers to two cases of temporally associated thrombocytopenia. Later, on p. 206 of F23-1799, the non-public AEFI report of March 25th, 2021, showed 3 cases of thrombocytopenia.

May 1st, 2021 – P. 287, FOI F23-1799:

Below, the public-facing BC CDC AEFI report from December 13th, 2020, to May 1st, 2021 stated:

“No safety signals have been identified in the reports received in BC to date”

“Serious events have not been reported at rates higher than expected compared to background rates.”

“There have been no reports of thrombosis with thrombocytopenia syndrome (TTS) reported in BC to date;”




The above-highlighted statements from the public-facing BC CDC AEFI report of May 1st, 2021, are misleading when compared to the non-public BC CDC AEFI reports.

March 25th, 2021 – P. 205, FOI F23-1799:

Below,

The non-public BC CDC AEFI report shows 523 Total AEFI, 144 Serious AEFI, 94 Anaphylaxis AEFI and their respective rate per 100,000 doses are 84.37, 23.23, and 15.16.

Serious AEFI represent 27.5% of Total AEFI.

The COVID-19 vaccine Serious AEFI rate is unexpectedly 15.7 times greater than the historic flu vaccine Serious AEFI rate (background rate). This is an obvious safety signal.

The total AEFI rate of the historic flu is 6.5 per 100,000 doses

The Serious AEFI rate of the historic flu is 1.48 per 100,000 doses

Pandemic of the Newly Injected

In the Monika Naus email of January 28th, 2021, there’s a link to a CDC slide deck that is no longer available for some reason. I managed to recover it. Its 7th slide shows AEFI from the V-Safe database that took New York Attorney Aaron Siri 18 months to obtain via the US courts. The slide shows US AEFI data as of January 14th, 2021, and the slide deck was published on January 27th, 2021.



Above is the sample size, which makes the numbers below extremely significant. The “All vaccines” red rectangle in the table below means All COVID-19 vaccines.



The above statistics were compiled from self-reporting recipients of the COVID-19 vaccines within 7 days after receipt of the vaccine. This is what you can expect within 7 days. I wonder if this is why Public Health Officials in BC and around the globe required you to wait between 14 days and 21 days before they would categorize you as being vaccinated?

*** The V-Safe data in the table above was in the possession of Bonnie Henry and the BC CDC since January 27th, 2021. ***

Comparing the AEFI rates between the first and second doses of Pfizer, it is evident that toxicity and harms increase with additional doses. We also see that when comparing dose 1 of Pfizer and Moderna, Moderna is more toxic than Pfizer. If the above level of risks had been disclosed to the public, it would have likely caused massive vaccine hesitancy in most sane people.

You can imagine that a large percentage of the population started having one or more of these very common reactions very early in the COVID-19 vaccine rollout and, believing the vaccines to be safe, attributed them to COVID-19 itself.

*** The COVID-19 vaccines caused a massive immediate surge in demand for healthcare. MASS INJURIES ***

The works of Denis Rancourt and Ed Dowd are what immediately come to my mind in support of mass injuries. Ed Dowd pointed out that the US Department of Labor maintained statistics on disabled people. Coinciding with the COVID-19 vaccine rollout we see a massive surge of people self-reporting as disabled. Here are the monthly year-over-year changes in disabilities observed by Ed Dowd.

Review of FOI F23-1799 and BC Public Health’s Handling of COVID-19 Vaccines AEFI – Part 1
Lex Acker
Mar 2
https://substack.com/app

Mark. $27

Bearish 100%

Imagine being dumb enough to own this stock knowing that rfk and kash will rescind their liability clause!! Can’t wait till these fuckers pay for what they have done

Winning no matter what
Will be short lived

Time is at hand

Nothing says unbiased better, am I right? leavening the the istitution that regulates for a company that it regulates. Hot garbage 🗑️ humans with no morals. 

PFE hires former head of FDA/CDER as CMO:

https://e.endpointsnews.com/t/t-l-skthrhy-pktjidrih-t/ Patrizia Cavazzoni, the FDA’s for­mer head of drug regula­tion, will become Pfizer’s new chief medical officer, End­points News has learned. Cavazzoni led the FDA’s Cen­ter for Drug Evaluation and Research (CDER), which oversees all drug applications, for about four years during the Biden administration. Cavazzoni resigned from the FDA immediately prior to Trump’s inauguration.

Summit Therapeutics Announces Clinical Trial Collaboration with Pfizer to Evaluate Ivonescimab in Combination with Pfizer Antibody Drug Conjugates (ADCs)

https://www.biospace.com/press-releases/summit-therapeutics-announces-clinical-trial-collaboration-with-pfizer-to-evaluate-ivonescimab-in-combination-with-pfizer-antibody-drug-conjugates-adcs

-they were born winners-

"They win no matter what.."
Excellent synopsis..

Key word there is at the end with establishment in the line. The Media is on the payroll, it harmed way more than it helped. Folks need to go to jail. But hay how about them dividends. Folks supporting this company is insane. The aMount of mental gymnastics to avoid acknowledging Al the dirty stuff that they have done in the past even before the Jab is wild. In every instance they made more than they lost in the lawsuits. There is no incentive to be honest with the customer because they win no matter what. 

This time around though things will be different. The "unintentional lab leaks" won't be tolerated.
Think about it. Toying with mother nature to create a deadly virus on purpose is insanity and pure evil.
More of this will be dealt with so harshly that no one in the Chinese Communist Party will be
enjoying any more Wonton Batshit Soup.

-history repeats itself - New coronavirus with potential to cause pandemic discovered in China

The new virus is even closer related to MERS, a deadlier type of coronavirus that kills up to a third of people it infects.

HKU5-CoV-2 is strikingly similar to the pandemic virus, sparking fears that history could repeat itself just two years after the worst was declared over.



https://www.dailymail.co.uk/health/article-14421599/coronavirus-potential-cause-pandemic-discovered-china.html

great choice!

wow. now cutting off that gravy bowl will hurt. let's see what develops from this.
and how much mulah came back around from Pfizer into Falsi's pocket and to others in congress and media who gave their all to support the killer jabs? Investigations ongoing. This could get really nasty.

Yes, but the Pfizer is being laid bare and it is not what it appeared to be in the past.
I do agree though it is getting cheap. If it returns to around 22 I will go from short to long.

Another company is about to enter that market with a much better product.
What hurts even much more is the mRNA stuff being put on hold.
Add that to growing call for liability issues could put the nail in the coffin.

How does one know
Not true (eom).

Trump to pull covid vaccines off market

For reassessment

Click on "For reassessment" Trump may BAN COVID VACCINES

- Trump's Potential Ban on COVID Vaccines (0:01)
- Criticism of Operation Warp Speed (0:54)
- Media Narratives and Vaccine Criticism (2:11)
- Breaking the Collusion Between Media and Big Pharma (3:48)
- Future Actions and Accountability (7:09)
- Health Ranger Store Promotions (8:41)
- Final Thoughts and Closing (11:43)

For more updates, visit: http://www.brighteon.com/channel/hrreport

PFE discontinues commercialization of Beqvez due_to_low_demand:

https://finance.yahoo.com/news/pfizer-shelves-haemophilia-gene-therapy-172523645.html

Conventional therapies for hemophilia, including PFE’s Hympavzi (#msg-175217202), are sufficiently safe, effective, and convenient that gene-therapy solutions are a tough sell—for the entire industry, not just PFE.

The discontinuation of Beqvez will have a near-zero effect on PFE's financials since hardly anyone was using the product.

Not true (eom).

Trump to pull covid vaccines off market

For reassessment

-history repeats itself-Covid vaccines saved almost 20million lives during the first year of their existence, according to estimates.

British grandmother Maggie Keenan became the first person in the world to get an approved jab on December 8, 2020.

The mRNA vaccines made by Moderna and Pfizer are estimated to have saved tens of millions of lives globally from Covid, including 3million in the US.

https://www.dailymail.co.uk/health/article-10944873/Covid-vaccines-saved-nearly-20MILLION-lives-year-worlds-roll-out.html

Good perspective

~~~ When facts are laid forth ~~~
(51:18)

Open for discussion

Dr. Tom Cowan

Pfizer is trading at a considerable discount:

Currently, Pfizer's stock is trading at just 18 times trailing earnings
All this negativity, however, does open up an opportunity for investors to buy the stock at a discount. Despite being a top company in the healthcare industry, investors are treating Pfizer as a highly risky business to invest in, and that could be a huge mistake
There's a significant discount here, as the average stock in the Health Care Select Sector SPDR Fund trades at more than 18 times its future profits.

And its high-yielding dividend, which pays 6.6%, can give investors plenty of incentive to be patient.

Agree

Prophetic indeed

Another angle

On the chopping block finally...let the guillotine find it's target.
https://www.fiercehealthcare.com/regulatory/mass-layoffs-hhs-cdc-cuts-1300-probationary-workers-reports-say?oly_enc_id=4924G0643390I0A

Those illegal immigrants from all over the world... the poorest of the poor that their countries neglected came pouring across the border with all the infections and other hitchhikers attached. Kennedy was posted to the world by MSM to be an anti vaxxer which was never the case.
When I go to buy moonshine, do I buy from a mountain family that has been producing it for generations or do I buy from some yaahoo off the street?
Details matter.
https://www.investors.com/news/technology/rfk-jr-senate-confirmation-hhs-secretary/