FORM 4
[ ] Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).         
UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP OF SECURITIES
                                                                                  
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Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934 or Section 30(h) of the Investment Company Act of 1940
                      

1. Name and Address of Reporting Person *

GLUCK FREDERICK W
2. Issuer Name and Ticker or Trading Symbol

CytomX Therapeutics, Inc. [ CTMX ]
5. Relationship of Reporting Person(s) to Issuer (Check all applicable)

__ X __ Director                      _____ 10% Owner
_____ Officer (give title below)      _____ Other (specify below)
(Last)          (First)          (Middle)

743 SAN YSIDRO ROAD
3. Date of Earliest Transaction (MM/DD/YYYY)

8/9/2016
(Street)

SANTA BARBARA, CA 91308
(City)        (State)        (Zip)
4. If Amendment, Date Original Filed (MM/DD/YYYY)

 
6. Individual or Joint/Group Filing (Check Applicable Line)

_ X _ Form filed by One Reporting Person
___ Form filed by More than One Reporting Person

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1.Title of Security
(Instr. 3)
2. Trans. Date 2A. Deemed Execution Date, if any 3. Trans. Code
(Instr. 8)
4. Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4 and 5)
5. Amount of Securities Beneficially Owned Following Reported Transaction(s)
(Instr. 3 and 4)
6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4)
Code V Amount (A) or (D) Price
Common Stock   8/9/2016     M    31767   A $1.1339   179558   D    
Common Stock   8/9/2016     M    16612   A $0.945   196170   D    
Common Stock   8/9/2016     M    27606   A $1.4489   223776   D    
Common Stock   8/9/2016     M    17139   A $1.5749   240915   D    
Common Stock                  331643   I   By Frederick W. Gluck 1997 Family Trust dtd July 28, 1997   (1)
Common Stock                  22111   I   By Richlin Partners, LLC   (2)
Common Stock                  3200   I   By spouse  

Table II - Derivative Securities Beneficially Owned ( e.g. , puts, calls, warrants, options, convertible securities)
1. Title of Derivate Security
(Instr. 3)
2. Conversion or Exercise Price of Derivative Security 3. Trans. Date 3A. Deemed Execution Date, if any 4. Trans. Code
(Instr. 8)
5. Number of Derivative Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4 and 5)
6. Date Exercisable and Expiration Date 7. Title and Amount of Securities Underlying Derivative Security
(Instr. 3 and 4)
8. Price of Derivative Security
(Instr. 5)
9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4) 10. Ownership Form of Derivative Security: Direct (D) or Indirect (I) (Instr. 4) 11. Nature of Indirect Beneficial Ownership (Instr. 4)
Code V (A) (D) Date Exercisable Expiration Date Title Amount or Number of Shares
Stock Option (right to buy)   $1.1339   8/9/2016     M         31767      (3) 3/23/2021   Common Stock   31767   $0.00   0   D    
Stock Option (right to buy)   $0.945   8/9/2016     M         16612      (3) 2/25/2023   Common Stock   16612   $0.00   0   D    
Stock Option (right to buy)   $1.4489   8/9/2016     M         27606      (3) 5/23/2024   Common Stock   27606   $0.00   0   D    
Stock Option (right to buy)   $1.5749   8/9/2016     M         17139      (3) 2/8/2025   Common Stock   17139   $0.00   0   D    

Explanation of Responses:
( 1)  The Reporting Person is a trustee of Frederick W. Gluck 1997 Family Trust dtd July 28, 1997.
( 2)  Richlin Partners, LLC is an entity owned of record by the spouse of the Reporting Person.
( 3)  100% of the shares subject to the option are fully vested and exercisable.

Reporting Owners
Reporting Owner Name / Address
Relationships
Director 10% Owner Officer Other
GLUCK FREDERICK W
743 SAN YSIDRO ROAD
SANTA BARBARA, CA 91308
X



Signatures
/s/ Cynthia J. Ladd, as Attorney-in-Fact for Frederick W. Gluck 8/11/2016
** Signature of Reporting Person Date


Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 4(b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB control number.
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