Sanofi (SNY) 銘柄情報

Drug Companies making Epilepsy medication
MRNS $10.08
CERE $43.16
STOK $4.98
UCBJF $102.00
SNY $45.63
PFE $27.00
OTSUK $18.36
$RSPI .0013
RespireRx Pharmaceuticals Ticker: RSPI
Is working on Revolutionary New Hope:
KRM-II-81 Drug-Resistant Epilepsy Patients

Link found on National Library of Medicine
The imidazodiazepine, KRM-II-81: An example of a newly emerging generation of GABAkines for neurological and psychiatric disorders

https://pubmed.ncbi.nlm.nih.gov/35041859/

https://www.neurexplain.com/2024/01/17/revolutionary-krm-ii-81-a-new-hope-for-drug-resistant-epilepsy-patients/

National Institutes of Health
A clinical case of a 19-year-old male patient with pharmacoresistant seizures occurring following parieto-occipital tumor-resection at age 6 ...
KRM–II–81 suppresses epileptifom activity across the neural network of cortical tissue from a patient with pharmacoresistant epilepsy
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10784158/

The value of human epileptic tissue in the characterization and development of novel antiepileptic drugs: The example of CERC-611 and KRM-II-81
https://www.sciencedirect.com/science/article/abs/pii/S000689931930410X

https://ih.advfn.com/stock-market/NASDAQ/first-wave-biopharma-FWBI/stock-news/92040537/form-8-k-current-report

https://finance.yahoo.com/m/808ec522-bbcd-3db0-a334-2d054dbf3797/sanofi-to-buy-provention-bio.html

Took a position here...looking to hold awhile...
$SNY

$SNY Why AstraZeneca's and Sanofi's Bad News Could Be Great News for Pfizer and Moderna

https://fool.com/investing/2020/12/16/why-astrazenecas-and-sanofis-bad-news-could-be-gre/

JUST IN: $SNY Is Novavax Stock a Buy?

The COVID-19 pandemic has affected daily life in a number of ways, and a vaccine for the disease is probably our best hope for a return to normal. Thankfully, well over a dozen companies are working to develop a vaccine for the novel coronavirus at an incredible pace; one of these, Novavax (N...

Got this from SNY - Is Novavax Stock a Buy?

Here's Why Investors Should Follow Sanofi $SNY and GlaxoSmithKline's $GSK New #Coronavirus #COVID19
Collaboration


https://www.fool.com/investing/2020/04/30/heres-why-investors-should-follow-sanofi-and-glaxo.aspx

Moncef Slaoui, a former GlaxoSmithKline   executive, will lead “Operation Warp Speed,” Trump’s push to accelerate the vaccine development process for COVID-19.
SNY partnered with GSK last April to make a Covid-19 vaccine.
Food for thought.

Nice find.

Innovation Pharmaceuticals Informed Next Phase of Brilacidin Coronavirus (COVID-19) Testing to Begin Week of May 4

Provided by GlobeNewswire

Apr 27, 2020 9:30 AM EDT

WAKEFIELD, Mass., April 27, 2020 (GLOBE NEWSWIRE) -- Innovation Pharmaceuticals (OTCQB:IPIX) (“the Company”), a clinical stage biopharmaceutical company, is pleased to report the Company has been informed by researchers at the U.S. Regional Biocontainment Laboratory (RBL) that continued coronavirus (COVID-19) testing of Brilacidin, the Company’s defensin-mimetic drug candidate, is scheduled to begin the week of May 4.

Sanofi warns Europe on Covid-19 vaccine

French pharma group has two candidates in pipeline

https://www.ft.com/content/5884987a-e1d1-476a-b538-368e2a915480

Sanofi would be able to deliver an effective vaccine within the next 18 months but warned that the bigger challenge would be ramping up production to meet potentially massive demand.

Sanofi Pasteur vaccine division employs about 10,000 people and has 12 factories globally. It has two Covid-19 vaccines in development: one of which is a traditional protein-based vaccine, and another known as an mRNA vaccine, which is a new type that promises to be faster to manufacture but remains as yet unproven.



Sanofi is also testing the efficacy of two of its drugs already approved for other uses against Covid-19, including the malaria drug hydroxychloroquine and Kevzara, which is usually used to treat rheumatoid arthritis. 

On Friday, the company confirmed its goal for earnings per share to rise 5 per cent this year, after reporting higher first-quarter sales and profits buoyed by people stockpiling its drugs during the Covid-19 outbreak. 

That first-quarter stockpiling boost will be “largely offset” by an expected slowdown in the second quarter.

Like-for-like revenue rose 6.6 per cent to €8.97bn in the quarter to March 30 driven by higher sales of over-the-counter medicines for pain and fever, and eczema drug Dupixent.

Net income rose 16.1 per cent to €2bn.

Small Trial Suggests Antimalarial Drugs Not Effective For Treating Coronavirus

KATHERINE SELEY-RADTKE, THE CONVERSATION

6 APRIL 2020

On Saturday the Food and Drug Administration approved the use of two antimalarial drugs, hydroxychloroquine and a related medication, chloroquine, for emergency use to treat COVID-19. The drugs were touted by President Trump as a "game changer" for COVID-19.

However, a study just published in a French medical journal provides new evidence that hydroxychloroquine does not appear to help the immune system clear the coronavirus from the body.

The study comes on the heels of two others - one in France and one in China - that reported some benefits in the combination of hydroxychloroquine and azithromycin for COVID-19 patients who didn't have severe symptoms of the virus.

I am a medicinal chemist who has specialized in discovery and development of antiviral drugs for the past 30 years, and I have been actively working on coronaviruses for the past seven.

I am among a number of researchers who are concerned that this drug has been given too much of a high priority before there is enough evidence to show it is indeed effective.

There are already other clinical studies that showed it is not effective against COVID-19 as well as several other viruses. And, more importantly, it can have dangerous side effects, as well as giving people false hope.

The latter has led to widespread shortages of hydroxychloroquine for patients who need it to treat malaria, lupus and rheumatoid arthritis, the indications for which it was originally approved.

The idea that the combination of hydroxychloroquine with an antibiotic drug, azithromycin, was effective against COVID-19 gained more attention after a study published on March 17. This study described a trial of 80 patients carried out by Philippe Gautret in Marseille, France.

Although some of their results appeared to be encouraging, it should also be noted that most of their patients only had mild symptoms. Furthermore, 85 percent of the patients didn't even have a fever – one of the major telltale symptoms of the virus, thus suggesting that these patients likely would have naturally cleared the virus without any intervention.

In another study, posted on medRxiv, which has not yet been peer-reviewed, Chinese scientists from Renmin Hospital of Wuhan University, in Wuhan, China, gave hydroxychloroquine to patients with only mild infections who were free of medical issues, similar to the Gautret study. The results showed that the 31 patients who received the drug showed a lessening of their symptoms 24 hours earlier than patients in the control group.

In addition, pneumonia symptoms improved in 25 of the 31 patients versus 17 of 31 in the control group. As noted in several of the comments associated with the manuscript, there are issues related to the translation of the paper, thus clouding interpretations of some of the results. The paper also appears to focus more on pneumonia than COVID-19. However, these issues may be cleared up or addressed once the paper finishes the peer-review process.

But two other studies have conflicting results.

A second French group, led by Jean-Michel Molina, has now tested the hydroxychloroquine-azithromycin combination treatment in 11 patients at the Hôpital Saint-Louis in Paris, France, and their results were strikingly different.

Like the Marseille study, the Molina trial was also a small pilot study. Molina and colleagues used the same dosing regimen as Gautret. In contrast, however, to the Gautret study, eight of the 11 patients had underlying health conditions, and 10 of 11 had fevers and were quite ill at the time the dosing began.

These Paris researchers found that after five to six days of treatment with hydroxychloroquine (600 mg per day for 10 days) and azithromycin (500 mg on day 1 and 250 mg on days 2 to 5), eight of the 10 patients still tested positive for COVID-19.

Of these 10 patients, one patient died, two were transferred to the ICU and another had to be removed from the treatment due to serious complications.

In addition, a similar study in China also showed no difference in viral clearance after seven days either with or without the hydroxychloroquine with the patients in the trial. This supports Molina's findings.

Thus, despite the recent approval of this drug for use against COVID-19, questions remain as to the efficacy of this treatment.

As Molina and colleagues note: "Ongoing randomized clinical trials with hydroxychloroquine should provide a definitive answer regarding the alleged efficacy of this combination and will assess its safety."

Katherine Seley-Radtke, Professor of Chemistry and Biochemistry and President-Elect of the International Society for Antiviral Research, University of Maryland, Baltimore County.

https://www.thedailybeast.com/trump-reportedly-has-financial-interest-in-hydroxychloroquine-manufacturer

Malaria drug fails at hospital https://www.bloomberg.com/news/articles/2020-04-02/hyped-malaria-drug-not-showing-much-effect-at-one-paris-hospital

Yup. This is a trade for a flip

Bought in here today...

https://www.barrons.com/articles/coronavirus-covid-19-vaccine-program-51585341169?siteid=yhoof2&yptr=yahoo

I think unfortunately because this is a Pharma stock now a biotech...sad I sold out today 30 min charts look toppy and thought this one would have already run...

I’m confused, I would of thought this would have moved more. What am I missing?

is too late to join SNY SINCE VACCINE ALREADY APPROVE

pill instead of vaccine

i love SNY

hydroxychloroquine, market is slow, im fast

FDA about to speak...bought some here just in case gl2all.

Goldman Sachs rate Sanofi a buy.
Working on several new drugs plus a vaccine for virus .

News: $SNY Sanofi Is Paying a 172% Premium to Buy Synthorx -- and It Sounds Like a Good Deal for Both

On Dec. 9, pharmaceutical giant Sanofi (NASDAQ: SNY)  said it's buying immuno-oncology company Synthorx (NASDAQ: THOR) for $2.5 billion to boost its cancer and autoimmune program.  Considering the performance of Sanofi's businesses, the pipeline Synthorx brings to the ...

Got this from SNY - Sanofi Is Paying a 172% Premium to Buy Synthorx -- and It Sounds Like a Good Deal for Both

News: $SNY Here's Why Dermira Stock Popped Today

Shares of Dermira (NASDAQ: DERM) , a biopharmaceutical company, jumped at the beginning of today's trading session in response to good news from the Food and Drug Administration. Investors looking forward to a shortened review for the company's experimental eczema therapy drove the stock...

Find out more SNY - Here's Why Dermira Stock Popped Today

Time for puts - Zantac getting pulled from shelves.
Looking for a return to near $40.

News: $SNY 2 Biotech Stocks I Wouldn't Touch With a Broom

Drug development is a losing game full of highly trained professionals who would rather be lucky than talented at their jobs. This is because experimental new drugs fail so frequently that an entire career without one successful new drug discovery under their belts isn't uncommon. Doing everyth...

Got this from SNY - 2 Biotech Stocks I Wouldn't Touch With a Broom

BioNTech Teams up With Sanofi to Target Solid Tumors in $91.5 Million Deal...

As part of the deal, the French pharma giant will invest about $91.5 million in equity in BioNTech, a privately-held company. The investment follows BioNTech’s 2018 decision to exercise one of the option rights under the 2015 agreement to co-develop and co-commercialize the immuno-oncology candidate. The two companies will work to develop an investigational therapy that includes an mRNA mixture encoding immunomodulatory cytokines that are injected directly into the tumor. Local administration of immunotherapies to the tumor microenvironment provides the opportunity to stimulate innate and adaptive immune responses against tumors, while potentially avoiding toxicities related to systemic administration of immuno-modulatory therapeutics.

https://www.biospace.com/article/biontech-teams-up-with-sanofi-to-target-solid-tumors-in-91-5-million-deal/

Keep an eye on this sleeper with so much potential- a potential M&A target. IMO

Mymetics Corp. (otcqb: MYMX)

Imminent Catalysts:

1) Collaboration with Sanofi Pasteur(vaccine unit of giant pharma Sanofi) will conclude this year's (2018) end. Successful outcome will lead to either exclusive licensing deal of Mymetics' proprietary VLP platform for use in Sanofi's influenza vaccines or buyout.

2) Collaboration with Anergis,SA which preclinical results expected at year's (2018) end or 1st Q of 2019. A successful outcome will lead to exclusive worldwide licensing deal with Mymetics' proprietary VLP platform for use in all of Anergis' allergy immunotherapy vaccines.

3) MACIVIVA(Manufacturing for cold chain independent virosome based vaccines) of which Mymetics is leading a consortium of 4 other companies including giant CMO Catalent(NYSE:CTLT) using Mymetics' HIV-1 vaccine will conclude this month of November 2018.

4) A possibility of advancing Mymetics' HIV-1 vaccine to Phase Ib - II under the framework of MACIVIVA project.



GLTA

Consortium partner tweeted:

"Upperton abstract, entitled Developing Cold Chain Independent Vaccines - Spray-drying of Virosomes to Produce Dry Powder Formulations, has been Accepted for Poster presentation at the 2018 AAPS Annual Meeting to be held November 4-7, 2018 in DC"

https://twitter.com/UppertonLtd/status/1020235017056923648

Under-the-Radar R&D Biotech microcap with so much potential!

>>>Mymetics(otcqb:MYMX) - Sanofi Pasteur [vaccine unit of Sanofi(nyse:SNY)]<<<
short term catalyst ~June 2018 collaboration result/decision point!

Mymetics' (OTCQB:MYMX) extremely undervalued @ $ 0.04

>>> Vaccine Pipeline:
HIV
Malaria
Intranasal Influenza
RSV
Chikungunya

>>> Partnerships:
Anergis ---------------------------------------------------------- April 2018 - present
Sanofi Pasteur (vaccine unit of Sanofi : NYSE: SNY) --- Oct.2016 - present
Astellas Pharma (2nd Largest Japanese Pharma Co.)-- Jan.2014 - July 2016
Catalent (NYSE:CTLT) ---April 2015 - Present
Bachem (SIX:BANB) ------April 2015 - Present
Upperton, UK -------------- April 2015 - Present
Chimera Biotec, Germany-April 2015 - Present
Texas Biomedical Research Institute - Sept.2014 - Present

>>> Funding Organizations:
Bill & Melinda Gates Foundation - HIV-1 vaccine
PATH MVI ------------------------------ Malaria Transmission Blocking Vaccine
Swiss Tropical & Public Health Institute --- Malaria Vaccine
European Union Horizon 2020---------------MACIVIVA (Manufacturing Process For Cold-Chain Independent Virosome based Vaccines)-- Mymetics is leading a consortium of 4 other companies.

**** MACIVIVA *****
>>> MACIVIVA = Game Changer = Disrupting the vaccine industry worldwide!
MACIVIVA latest Progress' Reporting Period Posted: https://cordis.europa.eu/result/rcn/194900_en.html
Copy of latest MACIVIVA presentation (downloadable): https://www.mymetics.com/media-center/world-vaccine-congress-10-12-october-2017-barcelona/

>>> No More Pricks – Quick Dissolvable Tablet is Set to Disrupt the Vaccine Industry
http://investor.catalent.com/press-release/financial-news/no-more-pricks-%E2%80%93-quick-dissolvable-tablet-set-disrupt-vaccine-industry https://vimeo.com/217946374<<< click video insert

>>> Dr. Christopher Henney, currently Anthera Pharmaceuticals(ANTH) and Cascadian Therapeutics (formerly Oncothyreon) - recently acquired by Seattle Genetics, Chairman of the Board; Director at Cyclacel Pharmaceuticals and former Dendreon co-founder & CEO was once on board with this unknown microcap as Chairman of BOD but seems had a disagreement with the largest shareholder that led him and his Dendreon protege to leave in less than a year.
https://www.xconomy.com/san-francisco/2012/04/11/mymetics-ropes-in-dendreon-kpcb-vets-to-restart-vaccine-developer/

Share Structure:
Outstanding : 303.7million common shares (unchanged since 2014)
Float: ~ 91 million shares

>>> MYMX is leading this disruptive project.
https://cordis.europa.eu/docs/results/h2020/646/646122_PS/maciviva-project-concept.jpg

"click" on Company Overview: https://www.mymetics.com/about/


****taken from yahoo message board courtesy of nito****

April 16th 2018 - The Best Stock Investment For 2018 - Mymetics Corp. (MYMX)
https://askwarrenbuffet.blogspot.com/2018/02/the-best-investment-for-2018-is.html

Sanofi strikes again! 2nd acquisition deal this month. Who's Next?

"We can still do additional bolt on acquisitions," Chief Executive Olivier Brandicourt said on a call with reporters, adding that the company had a general target of EUR20 billion for acquisitions.

https://ih.advfn.com/p.php?pid=nmona&article=76572055

Microcap Mymetics Corp. (OTCQB:MYMX ) .03 on watch!

Partnerships:
Sanofi Pasteur (vaccine unit of Sanofi : NYSE: SNY) --- Oct.2016 - present
Astellas Pharma (2nd Largest Japanese Pharma Co.)-- Jan.2014 - July 2016
Catalent (NYSE:CTLT) ---April 2015 - Present
Bachem (SIX:BANB) ------April 2015 - Present
Upperton, UK -------------- April 2015 - Present
Chimera Biotec, Germany-April 2015 - Present
Texas Biomedical Research Institute - Sept.2014 - Present

Funding Organizations:
Bill & Melinda Gates Foundation - HIV-1 vaccine
PATH MVI ------------------------------ Malaria Transmission Blocking Vaccine
Swiss Tropical & Public Health Institute --- Malaria Vaccine
European Union Horizon 2020---------------MACIVIVA (Manufacturing Process For Cold-Chain Independent Virosome based Vaccines)--Mymetics is leading a consortium of 4 other companies.

"click" on Company Overview: https://www.mymetics.com/about/


*courtesy of nito from yahoo mymx message board*
https://finance.yahoo.com/quote/MYMX/community?p=MYMX

https://www.wsj.com/articles/sanofi-nears-deal-to-buy-hemophilia-drugmaker-bioverativ-for-more-than-11-5-billion-1516584141

A bump on the road but still going!

https://seekingalpha.com/article/4124256-sanofi-wants-make-major-footprint-multiple-sclerosis-space

SANOFI-MYMETICS collaboration result anytime now? Come on Mymetics bring the news!!! Will it be JV or Buyout???

https://seekingalpha.com/article/4109199-alnylam-sanofi-achieve-rnai-first

SANOFI-MYMETICS

https://insiderfinancial.com/heres-our-take-on-mymetics-corp-otcmktsmymx/146314/

https://seekingalpha.com/article/4086761-alnylam-sanofi-produce-monster-alternative-hemophilia-market

Picked up a starter. Going long. $SNY

Sanofi working on intra-nasal Fluzone to compete with Aztra Zeneca's Flumist?

"There are a number of quadrivalent options for consumers to choose from this season. One option that is available -- but which the CDC suggests you steer clear -- is AstraZeneca's nasal spray FluMist. Despite being a handy alternative to getting a shot,studies have suggested that FluMist simply isn't effective compared to the other flu vaccines being offered"

https://www.fool.com/investing/2017/02/11/flu-death-rates-just-hit-the-epidemic-threshold-bu.aspx

http://finance.yahoo.com/news/mymetics-starts-research-project-sanofi-100000417.html

http://www.mymetics.com/

"In 2017 and beyond we will continue to simplify and reshape the company," Chief Executive Oliver Brandicourt told journalists. "We will be supported by our current growth engine businesses: Sanofi Genzyme, vaccines and consumer healthcare".

http://finance.yahoo.com/news/drugmaker-sanofi-sees-weak-2017-082546194.html



The keyword is SIMPLIFY and that's exactly the partnership is all about. IMO, Sanofi is aiming of simplifying the old and traditional method of making their virus-based vaccines to reduce costs as well as improving effectiveness of their vaccines not to mention the broad range application of Mymetics' virosome-based VLP platform.

Is Mymetics the next acquisition target?

"In 2017 and beyond we will continue to simplify and reshape the company," Chief Executive Oliver Brandicourt told journalists. "We will be supported by our current growth engine businesses: Sanofi Genzyme, vaccines and consumer healthcare".

http://finance.yahoo.com/news/drugmaker-sanofi-sees-weak-2017-082546194.html



The keyword is SIMPLIFY and that's exactly the partnership is all about. IMO, Sanofi is aiming of simplifying the old and traditional method of making their virus-based vaccines to reduce costs as well as improving effectiveness of their vaccines not to mention the broad range application of Mymetics' virosome-based VLP platform.

Is Mymetics the next acquisition target?

SNY & Tiny $GOVX @ .06, $3.2M market cap featured in Zika article.

Feb 1, 2017:

Link:
http://www.pharmavoice.com/article/2017-2-zika-research/

Sanofi and Mymetics Corp. (otcbb:MYMX) partners for virosome influenza vaccine. The project is to evaluate influenza vaccines based on Mymetics' proprietary Virus Like Particle(VLP) technology platform versus Egg-based split vaccines.

http://ih.advfn.com/p.php?pid=nmona&article=73038267


Mymetics website: http://www.mymetics.com/

Sanofi Adds Costa Rica To Dengvaxia Approval List

http://marketexclusive.com/sanofi-sa-nysesny-adds-costa-rica-dengvaxia-approval-list/8377/?icd1