Revolution Medicines Inc (RVMD)

Well this doc has what appears to me to be a negative take on the trial data:
https://www.drvinayprasad.com/p/daraxonrasib-in-pancreas-cancer

So the audience delivers a standing ovation to the presentation and this guy pooh poohs it

Won’t let me paste that 2hr ago Wainwright raised target from$169 to $195

 

 

Adam Feuerstein ✡️
@adamfeuerstein
·
2h
Today’s STAT @ #ASCO26 newsletter

A momentous standing O for daraxonrasib
$RVMD
--------------------
Kiwi

I will share this https://www.fiercebiotech.com/biotech/aacr-revolution-rolls-pancreatic-cancer-ras-wave-rises

I wonder if Merck is kicking itself for passing on RVMD two months ago.

Revolution Medicines shares jump on breakthrough pancreatic cancer trial resultsApril 13, 2026 10:32 AM
IH Market News
Revolution Medicines (NASDAQ:RVMD) surged 33% on Monday after announcing positive topline findings from its Phase 3 RASolute 302 trial of daraxonrasib in previously treated metastatic pancreatic ductal adenocarcinoma patients.The study achieved all primary and key secondary endpoints, including both progression-free survival and overall survival. Daraxonrasib delivered a median overall survival of 13.2 months, compared with 6.7 months for standard chemotherapy, corresponding to a hazard ratio of 0.40.The company said it plans to submit the data to global regulators, including the U.S. Food and Drug Administration, as part of a future New Drug Application under a Commissioner’s National Priority Voucher. Full results are scheduled to be presented at the 2026 American Society of Clinical Oncology Annual Meeting.Daraxonrasib is designed as a multi-selective inhibitor targeting RAS(ON) proteins, aiming to address cancers driven by oncogenic RAS mutations. Pancreatic cancer is considered one of the most RAS-dependent cancers, with more than 90% of patients carrying tumors linked to RAS mutations.The RASolute 302 trial included patients with a broad range of RAS variants, as well as individuals without identified RAS mutations. Primary endpoints focused on progression-free and overall survival in patients with RAS G12-mutant tumors, while secondary endpoints evaluated outcomes across the full study population.Following the first interim analysis, the company confirmed that all progression-free survival and overall survival results are now considered final.Revolution Medicines stock price

Original: Revolution Medicines shares jump on breakthrough pancreatic cancer trial results

Patients who took the daily pill, called daraxonrasib, lived a median of 13.2 months, compared to 6.7 months for patients who received chemotherapy.

$RVMD: Now $133......... took longer for this buyout than thought...........

So those Jan 2026 $120 calls were soooooooooooo wrong.

Ughhhhhhhhhhhhhhhhhhhh

I saw it but the timing was offffffffffffffffff


https://investorshub.advfn.com/boards/read_msg.aspx?message_id=177152384


$REPL is falling on this news.............. now $1.77.............. thats a 60% drop from last week.


GO $RVMD


GO $RVMD

Revolution Medicines shares slide after Merck reportedly walks away from takeover talksJanuary 26, 2026 2:51 PM
IH Market News
Merck & Company Inc (NYSE:MRK) has reportedly ended discussions to acquire Revolution Medicines Inc (NASDAQ:RVMD) after the two sides failed to agree on valuation, according to the Wall Street Journal, citing people familiar with the situation. The talks had centered on a potential transaction that could have valued the oncology-focused biotech at around $30 billion.News of the breakdown triggered a sharp sell-off in Revolution Medicines’ stock, which fell 20.9% in premarket trading on Monday. The decline followed weeks of heavy speculation that had driven the company’s market value up from roughly $16 billion to more than $22 billion earlier this month.Sources indicated that negotiations stalled primarily over price, reflecting Merck’s disciplined stance as it pursues acquisitions in the oncology space. Addressing the company’s financial capacity at a recent conference, Merck CEO Rob Davis said, “We are not limited from a balance sheet,” while adding that the group remains focused on transactions of up to $15 billion.Revolution Medicines is advancing a pipeline of experimental therapies targeting RAS, a key molecular driver in several hard-to-treat cancers. Its leading drug candidates are being studied in lung, pancreatic and colorectal cancers, with important clinical readouts expected in the first half of the year.Earlier market chatter had also linked AbbVie to a possible bid for Revolution Medicines, although those reports were later dismissed.Despite the collapse of the latest talks, some market observers note that acquisition interest could resurface if upcoming clinical data are positive or if another potential buyer steps in. In the meantime, Merck is concentrating on its existing portfolio as it prepares for the eventual loss of exclusivity for its blockbuster drug, Keytruda.Revolution Medicines stock priceMerck stock price

Original: Revolution Medicines shares slide after Merck reportedly walks away from takeover talks

RVMD heading to $5. they of course making some inhibitors as good lab reagent, not therapeutic drugs, Comparable to RXRX

$RVMD: There goes those Jan2026 $120 $RVMD calls...............


Like I said............. LIke clockwork.

https://investorshub.advfn.com/boards/read_msg.aspx?message_id=177152384

If you got them when I told you to yesterday, you gonna go have a niceeeeeeeeee PARTY tonite !

Now $122

GO $RVMD

RVMD Losing 1 Billion Dollars a year Company is burning cash faster then a oven also not even that great a of a pipeline ZERO Revenues no one is going to pay 32 Billion Dollars for this trash hell MRK dont even have 32 Billion and all ready has a heavy debt load just like ABBV Didnt have 32 Billion they only have 5 Billion with nearly 70 Billion in Debt all ready another false rumor fake news to drive the stock price up to squeeze the shorts and enrich the longs witch is mostly institutional investors mean while insiders are selling at a fericious pace better take the money and runnnn before MRK Denies the Rumoes like ABBV Did yesterday and the stock tanks Strong Sell here blant stock manipulation

$RVMD: Ripping higher now with $MRK possible Buyout


Up to $108 here near the EOD.

Watch those $120 January calls.


GO $RVMD

FDA Awards First-Ever National Priority Vouchers to Nine Sponsors

https://www.fda.gov/news-events/press-announcements/fda-awards-first-ever-national-priority-vouchers-nine-sponsors

RMC-6236 for pancreatic cancer

RVMD under $50

Dr Olive added: 'I’ve been working on pancreatic cancer for almost 20 years, and I’ve never seen preclinical results like these.

'I think there is a real chance this approach will help change the standard of care for pancreatic cancer patients, but only clinical trials can determine that

Breakthrough in fight against world's deadliest cancer - new drug shrunk up to 70% of pancreatic tumors in lab study

https://www.dailymail.co.uk/health/article-13284461/pancreatic-cancer-breakthrough-deadliest-disease-study.html

RVMD over $30

RVMD 10Q. 2/26