Eyetech To Announce Second Quarter 2005 Financial Results On July 27, 2005 NEW YORK, July 15 /PRNewswire-FirstCall/ -- Eyetech Pharmaceuticals, Inc. (NASDAQ:EYET), today announced that it plans to report second quarter 2005 financial results on Wednesday, July 27, 2005 after the U.S. financial markets close. (Logo: http://www.newscom.com/cgi-bin/prnh/20050407/EYETLOGO ) Eyetech's senior management will hold a conference call and webcast to discuss the results and provide a company update on Thursday, July 28, 2005 at 11:00 a.m. Eastern Time. Live audio of the conference call will be available to investors, members of the news media and the general public by dialing 888-275-0218 (in the United States) or 706-679-7756 (internationally). A playback of the call will be available through August 4, 2005 by dialing 800-642-1687, passcode 7698407 (in the United States) or 706-645-9291, passcode 7698407 (internationally). To access the call by live webcast, please log on to the Investor Relations section of our corporate website at http://www.eyetech.com/. An archived version of the webcast will be available at the same location through August 4, 2005. About Eyetech Pharmaceuticals, Inc. Eyetech Pharmaceuticals, Inc. is a biopharmaceutical company that specializes in the development and commercialization of novel therapeutics to treat diseases of the eye. Eyetech's initial focus is on diseases affecting the back of the eye. Eyetech is commercializing and further developing Macugen(R) (pegaptanib sodium injection) with Pfizer Inc for the treatment of neovascular AMD. Macugen is also being studied for other indications including diabetic macular edema and retinal vein occlusion. http://www.newscom.com/cgi-bin/prnh/20050407/EYETLOGO http://photoarchive.ap.org/ DATASOURCE: Eyetech Pharmaceuticals, Inc. CONTACT: Investors - Glenn Sblendorio, Chief Financial Officer, T: +1-212-824-3100, F: +1-212-824-3240, E-mail: ; or Media - Chris Smith, Public Relations & Corporate Communications, T: +1-212-824-3203, F: +1-212-824-3240, E-mail: , both of Eyetech Pharmaceuticals, Inc. Web site: http://www.eyetech.com/

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