US Market News
1月前
Cryoport Reports First Quarter 2026 Financial ResultsMay 4, 2026 4:05 PM
PR Newswire (US) First quarter revenue grew 16% year-over-year to $47.8 millionCommercial cell and gene therapy (CGT) revenue grew 26% year-over-year to $9.1 million, reflecting continued expansion in approved CGT programsLife Sciences Services revenue increased 18% year-over-year, led by 21% growth in BioStorage/BioServices Life Sciences Products revenue increased 15% year-over-year, driven by strong demand for cryogenic systems Supporting a record 766 global clinical trials and 21 commercially approved CGTs as of March 31, 2026Company raises full-year revenue guidance to $192 million - $196 millionNASHVILLE, Tenn., May 4, 2026 /PRNewswire/ -- Cryoport, Inc. (NASDAQ: CYRX) ("Cryoport" or the "Company"), a leading global provider of integrated temperature-controlled supply chain solutions for the life sciences, today announced financial results for its first quarter (Q1) of 2026. Jerrell Shelton, CEO of Cryoport, commented, "Cryoport delivered a strong start to 2026 with first-quarter revenue of $47.8 million, up 16% year-over-year, reflecting a continuation of our momentum over the past several quarters across our integrated services and products platform. Revenue in support of commercial Cell and Gene Therapies (CGT) grew 26% to $9.1 million, while clinical trial support revenue grew 18% to $12.9 million. We continue to support one of the industry's broadest CGT pipelines, and our leadership across both clinical and commercial programs positions us well for sustainable growth."Our Life Sciences Services segment delivered another strong quarter, with revenue increasing 18% year-over-year, including 21% growth in BioStorage/BioServices. This performance reflects the increasing scope and complexity of the Cell & Gene Therapy programs we support and underscores the critical role we play in supporting our clients with our integrated, temperature-controlled supply chain services."Our Life Sciences Products segment also performed very well, generating 15% revenue growth, driven by global demand for MVE Biological Solutions' cryogenic systems. MVE continues to innovate and further solidify its position as the global leader in high-quality cryogenic systems."This growth across both our reporting segments, combined with solid gross margins and continued operational discipline, drove a $2.2 million year-over-year improvement in adjusted EBITDA from continuing operations, advancing us meaningfully along our "pathway to profitability.""Looking ahead, we see multiple growth catalysts extending beyond 2026, including the planned launch of BioServices operations at our Global Supply Chain Center in Paris, France in the third quarter, and the planned opening of our new Global Supply Chain Center in Santa Ana, California in the fourth quarter. These strategic investments expand our global footprint in key geographies and further strengthen our ability to support the advancement and commercialization of life-saving therapies globally. Reflecting on our strong performance in the first quarter and increased visibility into the remainder of the year, we are raising our full-year revenue guidance to $192 million to $196 million," concluded Mr. Shelton.The following table presents Q1 2026 revenue compared with Q1 2025:Cryoport, Inc. and Subsidiaries
Revenue
Three Months Ended
March 31,
(unaudited)(in thousands)20262025% ChangeLife Sciences Services$ 26,898$ 22,86518 %BioLogistics Solutions21,66818,53117 %BioStorage/BioServices 5,2304,33421 %Life Sciences Products$ 20,900$ 18,17515 %Total Revenue$ 47,798$ 41,04016 %BioLogistics Solutions revenue increased 17% year-over-year in Q1 2026, driven by increasing customer activity, continued commercial product maturation, and clinical advancement within the CGT market. BioStorage/BioServices revenue grew 21% year-over-year, reflecting strong demand for our expanded, integrated services offering, which provides seamless, secure handling of temperature-sensitive materials across our global network.Revenue from the support of commercial CGTs increased 26% year-over-year to $9.1 million and as of March 31, 2026, the number of commercial therapies we support increased to 21.As of March 31, 2026, Cryoport supported a total of 766 global clinical trials, a net increase of 55 clinical trials over March 31, 2025, with 91 of these clinical trials in Phase 3. The number of trials by phase and region are as follows: Cryoport Supported Clinical Trials by PhaseClinical TrialsMarch 31,202420252026Phase 1286304318Phase 2312328357Phase 3777991Total675711766
Cryoport Supported Clinical Trials by RegionClinical TrialsMarch 31,202420252026Americas518544569EMEA112118143APAC454954Total675711766In Q1 2026, four Biologics License Applications (BLA) / Marketing Authorization Applications (MAA) filings occurred. During the first quarter, Cryoport's customer, Rocket Pharmaceuticals, received U.S. Food and Drug Administration (FDA) accelerated approval for their gene therapy KRESLADI™ for the treatment of pediatric patients with severe leukocyte adhesion deficiency-I (LAD-I). Severe LAD-I is an ultra-rare, life-threatening pediatric genetic immunodeficiency characterized by recurrent infections and high early-childhood mortality without treatment. For the balance of 2026, we anticipate another 10 possible BLA/MAA application filings and 8 additional new therapy approvals.Operational milestonesLife Sciences ServicesBioServices launch at our Global Supply Chain Center in Paris, France, expected in Q3, 2026.Continued progress toward the launch of our state-of-the-art Global Supply Chain Center in Santa Ana, California, expected in Q4, 2026.First cryopreserved clinical trial patient materials shipped in Q1 for two of our clients at our IntegriCell® facilities in Belgium and the U.S.Cryoport Systems named Best Logistics & Supply Chain Management Supplier - Digital Technology & Software at the 2026 Asia Pacific Biopharma Excellence Awards in Singapore.Life Sciences ProductsMVE Biological Solutions (MVE) introduced its new Fusion® 800 Series, the next evolution of MVE's patented, award-winning Fusion technology, a self-sustaining cryogenic freezer that eliminates the need for a continuous liquid nitrogen (LN2) supply feed, delivering exceptional reliability, safety, and sustainability in a compact footprint designed for space-constrained environments.Release of MVE HE (High Efficiency) cryogenic storage systems series integrated with the new MVE CryoVerse™ Connect Controller platform.Financial HighlightsOn June 11, 2025, the Company completed the divestiture of its CRYOPDP specialty courier business to DHL Group as part of a strategic partnership. The results of CRYOPDP, a former business within Cryoport's Life Sciences Services segment, are presented as discontinued operations for all periods and are excluded from the non-GAAP financial measures in this release.RevenueTotal revenue for Q1 2026 was $47.8 million, compared to $41.0 million for Q1 2025, a year-over-year increase of 16%, or $6.8 million. Life Sciences Services revenue for Q1 2026 (representing 56% of our total revenue) was $26.9 million, compared to $22.9 million for Q1 2025, up 18% year-over-year, including BioStorage/BioServices revenue of $5.2 million, up 21% year-over-year. Life Sciences Products revenue for Q1 2026 (representing 44% of our total revenue) was $20.9 million, compared to $18.2 million for Q1 2025, up 15% year-over-year.Gross MarginTotal gross margin was 45.8% for Q1 2026, compared to 45.4% for Q1 2025. Gross margin for Life Sciences Services was 48.9% for Q1 2026, compared to 47.9% for Q1 2025. Gross margin for Life Sciences Products was 41.9% for Q1 2026, compared to 42.3% for Q1 2025.Operating Costs and ExpensesOperating costs and expenses were $31.5 million for Q1 2026, compared to $25.8 million for Q1 2025.Loss from Continuing OperationsLoss from continuing operations was $9.4 million for Q1 2026, compared to a loss of $6.7 million for Q1 2025. Net Loss – including Discontinued OperationsNet loss was $10.5 million for Q1 2026, compared to net loss of $12.0 million for Q1 2025.Net loss attributable to common stockholders for Q1 2026 was $12.5 million, or $0.25 per share, compared to net loss attributable to common stockholders of $14.0 million, or $0.28 per share for Q1 2025.Adjusted EBITDA from Continuing OperationsAdjusted EBITDA from continuing operations was a negative $0.6 million for Q1 2026, compared to a negative $2.8 million for Q1 2025.Cash, Cash equivalents, and Short-Term InvestmentsCryoport held $403.6 million in cash, cash equivalents, and short-term investments as of March 31, 2026.Note: All reconciliations of GAAP to adjusted (non-GAAP) figures above are detailed in the reconciliation tables included later in the press release.Additional InformationFurther information on Cryoport's financial results is included in the attached condensed consolidated balance sheets and statements of operations, and additional explanations of Cryoport's financial performance are provided in the Company's Quarterly Report on Form 10-Q for the quarter ended March 31, 2026, which is expected to be filed with the SEC on May 4, 2026. Additionally, the full report will be available in the SEC Filings section of the Investor Relations section of Cryoport's website at www.cryoportinc.com.Earnings Conference Call InformationIMPORTANT INFORMATION: In addition to the earnings release, a document titled "Cryoport First Quarter 2026 in Review", providing a review of Cryoport's business update, will be issued at 4:05 p.m. ET on Monday, May 4, 2026. The document is designed to be read in advance of the questions and answers conference call and will be accessible at https://ir.cryoportinc.com/news-events/ir-calendar.Cryoport management will host a conference call at 5:00 p.m. ET on May 4, 2026. The conference call will be in the format of a questions and answers session and will address any queries investors have regarding the Company's reported results. A slide deck will accompany the call.Conference Call InformationDate:Monday, May 4, 2026Time:5:00 p.m. ETDial-in numbers:1-800-717-1738 (U.S.), 1-646-307-1865 (International)Confirmation code:Request the "Cryoport Call" or Conference ID: 1191652Live webcast:'Investor Relations' section at www.cryoportinc.com or click here.
Please allow 10 minutes prior to the call to visit this site to download and install any necessary audio software.The questions and answers call will be recorded and available approximately three hours after completion of the live event in the Investor Relations section of the Company's website at www.cryoportinc.com for a limited time. To access the replay of the questions and answers click here. A dial-in replay of the call will also be available to those interested, until May 11, 2026. To access the replay, dial 1-844-512-2921 (United States) or 1-412-317-6671 (International) and enter replay entry code: 1191652#.About Cryoport, Inc.Cryoport, Inc. (Nasdaq: CYRX) is a leading global provider of integrated temperature-controlled supply chain solutions for the life sciences, with an emphasis on regenerative medicine. We support biopharmaceutical companies, contract manufacturers (CDMOs), contract research organizations (CROs), developers, and researchers with a comprehensive suite of services and products designed to minimize risk and maximize reliability across the temperature-controlled supply chain for the life sciences. Our integrated supply chain platform includes the Cryoportal® Logistics Management Platform, advanced temperature-controlled packaging, informatics, specialized biologistics, biostorage, bioservices, cryopreservation services, and cryogenic systems, which in varying combinations deliver end-to-end solutions that meet the rigorous demands of the life sciences. With innovation, regulatory compliance, and agility at our core, we are "Enabling the Future of Medicine™." Headquartered in Nashville, Tennessee, our company maintains a strong global presence with operations across the Americas, EMEA, and APAC.For more information, visit www.cryoportinc.com or follow via LinkedIn at https://www.linkedin.com/company/cryoportinc or @cryoport on X, formerly known as Twitter at https://x.com/cryoport for live updates.Forward-Looking StatementsStatements in this press release which are not purely historical, including statements regarding the Company's intentions, hopes, beliefs, expectations, representations, projections, plans or predictions of the future, are forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995. These forward-looking statements include, but are not limited to, those related to the Company's industry, business, long-term growth prospects, plans, strategies, acquisitions, future financial results and financial condition, such as the Company's outlook and guidance for full-year 2026 revenue and the related assumptions and factors expected to drive revenue, projected growth trends in the markets in which the Company operates, the Company's plans and expectations regarding the launch of new products and services, such as the expected timing and benefits of such products and services launches, the Company's expectations about future benefits of its acquisitions, and anticipated regulatory filings, approvals, label/geographic expansions or moves to earlier lines of treatment approved with respect to the products of the Company's clients. Forward-looking statements also include those related to the Company's expectations about future benefits relating to the CRYOPDP divestiture and strategic partnership with DHL (collectively, the "DHL Transaction"), the Company's plans regarding its Global Supply Chain Centers, including expected timing of future openings, the Company's plans and expectations relating to its strategic pivot to expand its global partnerships, and the Company's expectation of revenue contribution from IntegriCell's cryopreservation service centers throughout 2026. It is important to note that the Company's actual results could differ materially from those in any such forward-looking statements. Factors that could cause actual results to differ materially include, but are not limited to, risks and uncertainties associated with the effects of changing economic and geopolitical conditions, supply chain constraints, inflationary pressures, tariffs and other trade restrictions, foreign currency fluctuations, trends in the products markets, any U.S federal government shutdown, variations in the Company's cash flow, market acceptance risks, and technical development risks. Additional risks and uncertainties relating to the DHL Transaction include, but are not limited to, the risk that any disruption resulting from the DHL Transaction may adversely affect our businesses and business relationships, including with employees and suppliers. The Company's business could be affected by other factors discussed in the Company's SEC reports, including in the "Risk Factors" section of its most recently filed periodic reports on Form 10-K and Form 10-Q, as well as in its subsequent filings with the SEC. The forward-looking statements contained in this press release speak only as of the date hereof and the Company cautions investors not to place undue reliance on these forward-looking statements. Except as required by law, the Company disclaims any obligation and does not undertake to update or revise any forward-looking statements in this press release.Cryoport, Inc. and Subsidiaries
Condensed Consolidated Statements of Operations
Three Months Ended
March 31,
(unaudited)(in thousands, except share and per share data)20262025Revenue
Life Sciences Services revenue$ 26,898$ 22,865Life Sciences Products revenue20,90018,175Total revenue47,79841,040Cost of revenue:
Cost of services revenue13,74711,920Cost of products revenue12,13810,479Total cost of revenue25,88522,399Gross margin21,91318,641Operating costs and expenses:
Selling, general and administrative27,62021,901Engineering and development3,9073,934Total operating costs and expenses:31,52725,835Loss from operations(9,614)(7,194)Other income (expense):
Investment income3,0901,573Interest expense(432)(583)Other expense, net(2,368)(300)Loss before provision for income taxes(9,324)(6,504)Provision for income taxes(108)(234)Loss from continuing operations$ (9,432)$ (6,738)Loss from discontinued operations, net(1,112)(5,243)Net loss$ (10,544)$ (11,981)Paid-in-kind dividend on Series C convertible preferred stock(2,000)(2,000)Net loss attributable to common stockholders$ (12,544)$ (13,981)Net loss per share attributable to common stockholders - basic and diluted$ (0.25)$ (0.28)Weighted average common shares issued and outstanding - basic and diluted49,897,81749,947,012 Cryoport, Inc. and Subsidiaries
Condensed Consolidated Balance Sheets
March 31,December 31,
20262025(in thousands)(unaudited)
Current assets
Cash and cash equivalents$ 272,912$ 250,494Short-term investments130,722160,714Accounts receivable, net39,00433,359Inventories21,75023,188Prepaid expenses and other current assets6,1478,419Total current assets470,535476,174Property and equipment, net89,80585,448Operating lease right-of-use assets39,29939,720Intangible assets, net138,721138,082Goodwill22,13722,400Deposits2,0462,092Deferred tax assets1,0661,073 Total assets $ 763,609$ 764,989
Current liabilities
Accounts payable and other accrued expenses $ 15,937$ 15,283Accrued compensation and related expenses17,00712,980Deferred revenue2,314943Current portion of operating lease liabilities3,6414,133Current portion of finance lease liabilities419422Current portion of convertible senior notes, net185,390185,094Current portion of notes payable159163Total current liabilities224,867219,018Notes payable, net1,0271,087Operating lease liabilities, net39,17339,078Finance lease liabilities, net680741Deferred tax liabilities1,5801,354Other long-term liabilities663444Contingent consideration630629Total liabilities268,620262,351Total stockholders' equity494,989502,638Total liabilities and stockholders' equity$ 763,609$ 764,989Note Regarding Use of Non-GAAP Financial MeasuresTo supplement our financial statements, which are presented on the basis of U.S. generally accepted accounting principles (GAAP), the following non-GAAP measure of financial performance as defined in Regulation G of the Securities Exchange Act of 1934 is included in this release: adjusted EBITDA from continuing operations. Non-GAAP financial measures are not calculated in accordance with GAAP, are not based on any comprehensive set of accounting rules or principles and may be different from non-GAAP financial measures presented by other companies. Non-GAAP financial measures, including adjusted EBITDA from continuing operations, should not be considered as a substitute for, or superior to, measures of financial performance prepared in accordance with GAAP.Adjusted EBITDA from continuing operations is defined as loss from continuing operations adjusted for net interest expense, income taxes, depreciation and amortization expense, stock-based compensation expense, acquisition and integration costs, cost reduction initiatives, investment income, unrealized loss on investments, foreign currency loss, changes in fair value of contingent consideration and charges or gains resulting from non-recurring events, as applicable.Management believes that adjusted EBITDA from continuing operations provides a useful measure of Cryoport's operating results, a meaningful comparison with historical results and with the results of other companies, and insight into Cryoport's ongoing operating performance. Further, management and the Company's board of directors utilize adjusted EBITDA from continuing operations to gain a better understanding of Cryoport's comparative operating performance from period to period and as a basis for planning and forecasting future periods. Adjusted EBITDA from continuing operations is also a significant performance measure used by Cryoport in connection with its incentive compensation programs. Management believes adjusted EBITDA from continuing operations, when read in conjunction with Cryoport's GAAP financials, is useful to investors because it provides a basis for meaningful period-to-period comparisons of Cryoport's ongoing operating results, including results of operations, against investor and analyst financial models, helps identify trends in Cryoport's underlying business and in performing related trend analyses, and it provides a better understanding of how management plans and measures Cryoport's underlying business.Cryoport, Inc. and Subsidiaries
Reconciliation of GAAP loss from continuing operations to adjusted EBITDA(unaudited)
Three Months Ended
March 31,
20262025(in thousands)
GAAP loss from continuing operations$ (9,432)$ (6,738)Non-GAAP adjustments to loss:
Depreciation and amortization expense6,4026,134Acquisition and integration costs—1Cost reduction initiatives—216Investment income(3,090)(1,573)Unrealized loss on investments2,105193Foreign currency loss454245Interest expense, net432583Stock-based compensation expense2,3953,064Change in fair value of contingent consideration15(5,178)Income taxes108234Adjusted EBITDA from continuing operations$ (611)$ (2,819) View original content to download multimedia:https://www.prnewswire.com/news-releases/cryoport-reports-first-quarter-2026-financial-results-302761639.htmlSOURCE Cryoport, Inc. Original: Cryoport Reports First Quarter 2026 Financial Results
US Market News
3月前
Cryoport Reports Fourth Quarter and Full-Year 2025 Financial ResultsMarch 3, 2026 4:05 PM
PR Newswire (US)
FY 2025 revenue increased to $176.2 million, exceeding the high end of previous guidanceLife Sciences Services revenue grew 18% year-over-year in FY 2025, including a 22% rise in BioStorage/BioServices revenue Commercial cell and gene therapy revenue increased 29% year-over-year to $33.4 million in FY 2025Supported a record 760 global clinical trials and 20 commercially approved therapies as of December 31, 2025Full-year 2026 revenue guidance of $190 million to $194 million (8%-10% growth y-o-y)NASHVILLE, Tenn., March 3, 2026 /PRNewswire/ -- Cryoport, Inc. (NASDAQ: CYRX) ("Cryoport" or the "Company"), a leading global provider of integrated temperature-controlled supply chain solutions for the life sciences, today announced financial results for its fourth quarter (Q4) and year ended (FY) December 31, 2025.
Jerrell Shelton, CEO of Cryoport, commented, "2025 was a year of strong progress for Cryoport. We delivered full-year revenue of $176.2 million, exceeding the high end of our previous guidance and reflecting continued momentum across our core markets. We achieved double-digit revenue growth driven by expanding cell and gene therapy ("CGT") activity, with revenue from the support of commercial CGTs increasing 29% year-over-year to a record $33.4 million for FY 2025. Revenue from the support of clinical trials also remained solid, growing 14% to $47.1 million for FY 2025. At year-end, we supported a record 760 global clinical trials, representing approximately 70% of CGT trials. We believe our leadership position across both clinical and commercial programs, and the breadth of the development pipeline we support, provide a substantial foundation for sustained long-term growth."We continued to execute on our strategy of expanding our revenue streams and capturing more revenue per client as our Life Sciences Services revenue increased 18% year-over-year for FY 2025, including 22% growth in BioStorage/BioServices revenue. This performance reflects the expanding scale of the clinical and commercial programs we support and the increasing value customers place on our differentiated high-end supply chain solutions. While our primary focus remains on accelerating revenue growth and strengthening our market position, we continue to enhance operational discipline across the organization as we advance on our pathway to profitability. In 2025, our cost reduction initiatives contributed to our consolidated gross margin of 47% and a $12 million year-over-year improvement in adjusted EBITDA from continuing operations."Despite macro challenges, our Life Sciences Products segment grew 7% year-over-year and continues to support our Services businesses. MVE Biological Solutions' (MVE) focus on innovation and execution continues to further enhance its position as the global leader in the production of high- quality cryogenic systems. Recently MVE introduced integrated Condition Monitoring Solutions for its dry vapor shippers and also launched the Fusion® 800 Series, a revolutionary self-sustaining cryogenic freezer that can fit through a single door, which opens up substantial market opportunities."We also increased our investments into Cryoport Systems to support the traction that we are seeing across our broad portfolio of CGT clients. These targeted investments include the launch of our Global Supply Chain Center in Paris, France, the expansion of our Belgian operations to accommodate a key commercial client, and the facility buildout to consolidate three existing facilities in Irvine, California into one expansive Global Supply Chain Center in Santa Ana, California."Importantly, in 2025 we formed a strategic partnership with DHL Group, which included DHL's acquisition of CRYOPDP, providing a substantial capital infusion. Over time, we believe this relationship will enhance our positioning in the EMEA and APAC regions and strengthen our competitive industry profile. As part of our continuing strategic initiative to embed our market-leading solutions into the CGT ecosystem and improve our growth trajectory, we expanded our global partnerships by entering into strategic collaborations with Cardinal Health and Parexel."As we enter 2026 and balance the global macro puts and takes, we believe that our full-year revenue guidance of $190 million to $194 million is an appropriate starting point for the year," concluded Mr. Shelton.In tabular form, Q4 2025 and FY 2025 revenue compared to Q4 2024 and FY 2024, respectively, were as follows:Cryoport, Inc. and Subsidiaries
Revenue
Three Months Ended
December 31,
(unaudited)Years Ended
December 31,(in thousands)20252024% Change20252024% ChangeLife Sciences Services$ 25,005$ 21,47616 %$ 96,497$ 82,04418 %BioLogistics Solutions20,30517,47916 %78,13767,01917 %BioStorage/BioServices 4,7003,99718 %18,36015,02522 %Life Sciences Products$ 20,445$ 19,9762 %$ 79,680$ 74,7257 %Total Revenue$ 45,450$ 41,45210 %$ 176,177$ 156,76912 %BioLogistics Solutions revenue increased 17% year-over-year for FY 2025, supported by increasing customer activity and program advancement within the CGT market. BioStorage/BioServices revenue continued to experience strong year-over-year growth, increasing 22% for FY 2025, reflecting our clients' interest in our expanded and integrated services offering that provides a seamless and secure handling of temperature-sensitive materials through our global network.Revenue from the support of commercial CGTs increased 29% year-over-year to $33.4 million and we supported twenty (20) commercial therapies as of December 31, 2025.As of year-end, Cryoport supported a total of 760 global clinical trials, a net increase of 59 clinical trials over FY 2024, with 86 of these clinical trials in Phase 3. The number of trials by phase and region are as follows: Cryoport Supported Clinical Trials by PhaseClinical TrialsDecember 31,202320242025Phase 1282299313Phase 2311321361Phase 3828186Total675701760
Cryoport Supported Clinical Trials by RegionClinical TrialsDecember 31,202320242025Americas519537571EMEA112116138APAC444851Total675701760
In Q4 2025, five Biologics License Applications (BLA) / Marketing Authorization Applications (MAA) filings occurred. Post quarter-end, two additional BLA filings have occurred. During the fourth quarter, Cryoport's customer, Fondazione Telethon received FDA approval for their gene therapy Waskyra for the treatment of Wiskott-Aldrich Syndrome (WAS). During the fourth quarter, Bristol Myers Squibb received supplemental approval from the European Commission (EC) to expand the label of Breyanzi® as a third line treatment for relapsed or refractory follicular lymphoma. Lastly, in late December, Cryoport's customer Inovio Pharmaceuticals' BLA filing for INO-3107 was accepted by the FDA as a potential treatment for adults with Recurrent Respiratory Papillomatosis (RRP). For 2026, we anticipate 13 BLA/MAA application filings (including the two already filed), nine new therapy approvals and an additional two approvals for label/geographic expansions. In the near term, Cryoport has three clients that are anticipating new therapy approval decisions in March and April 2026.Operational milestonesLife Sciences ServicesLaunched state-of-the-art Global Supply Chain Center at the Charles de Gaulle airport in Paris, France, with our fourth Global Supply Chain Center in Santa Ana, California targeted for opening in late 2026. IntegriCell®, with cryopreservation service centers located near Liège, Belgium and in Houston, Texas, onboarded its first clients from whom we will have revenues throughout 2026.Launched cGMP sterile fulfillment/kitting services out of our Liège, Belgium facility supporting manufacturing needs for a key commercial client and the broader market. Cryoport Systems successfully achieved certification under ISO 21973:2020, the international standard for transportation of cells for therapeutic use published by the International Organization for Standardization (ISO), underscoring its commitment to safety and traceability within supply chain management of the rapidly expanding CGT industry.Life Sciences ProductsMVE Biological Solutions (MVE) introduced its integrated Condition Monitoring Solutions for its SC 4/2V and 4/3V dry vapor shippers, combining MVE's trusted cryogenic systems with advanced, real-time condition monitoring technology supplied by Tec4med, a Cryoport company. MVE launched its new Fusion® 800 Series, the next evolution of MVE's patented, award-winning Fusion technology, a self-sustaining cryogenic freezer that eliminates the need for a continuous liquid nitrogen (LN2) supply, delivering exceptional reliability, safety, and sustainability in a compact footprint designed for space-constrained environments.Financial HighlightsOn June 11, 2025, the Company completed its previously announced divestiture of its specialty courier CRYOPDP business to DHL Supply Chain International Holding B.V. ("DHL") as a part of a strategic partnership with DHL. The divestiture and strategic partnership are expected to enhance the Company's ability to develop its business, particularly in the EMEA and APAC regions, and to provide differentiated and high-value services aligned with Cryoport's long-term growth strategy. The results of CRYOPDP, a former business within Cryoport's Life Sciences Services segment, are presented as discontinued operations for all periods presented within the Condensed Consolidated Statements of Operations and Condensed Consolidated Balance Sheets included in this press release and are also not included in the non-GAAP financial measures presented herein.RevenueTotal revenue for Q4 2025 was $45.5 million, compared to $41.5 million for Q4 2024, a year-over-year increase of 10%, or $4.0 million. Life Sciences Services revenue for Q4 2025 (representing 55% of our total revenue) was $25.0 million, compared to $21.5 million for Q4 2024, up 16% year-over-year, including BioStorage/BioServices revenue of $4.7 million, up 18% year-over-year. Life Sciences Products revenue for Q4 2025 (representing 45% of our total revenue) was $20.4 million, compared to $20.0 million for Q4 2024, up 2% year-over-year.Total revenue for FY 2025 was $176.2 million, compared to $156.8 million for FY 2024, a year-over-year increase of 12%, or $19.4 million. Life Sciences Services revenue for FY 2025 was $96.5 million, compared to $82.0 million for FY 2024, up 18% year-over-year, including BioStorage/BioServices revenue of $18.4 million for FY 2025, compared to $15.0 million for FY 2024, up 22% year-over-year.Life Sciences Products revenue for FY 2025 was $79.7 million, compared to $74.7 million for FY 2024, up 7% year-over-year.Gross MarginTotal gross margin was 47.8% for Q4 2025, compared to 47.0% for Q4 2024. Gross margin for Life Sciences Services was 48.6% for Q4 2025, compared to 48.8% for Q4 2024. Gross margin for Life Sciences Products was 46.8% for Q4 2025, compared to 45.1% for Q4 2024.Total gross margin was 47.1% for FY 2025 compared to 44.4% for FY 2024. Gross margin for Life Sciences Services was 48.8% for FY 2025, compared to 46.9% for FY 2024. Gross margin for Life Sciences Products was 45.2% for FY 2025, compared to 41.7% for FY 2024.Operating Costs and ExpensesOperating costs and expenses were $31.7 million for Q4 2025, compared to $32.2 million for Q4 2024. Operating costs and expenses for FY 2025 decreased to $119.9 million, compared to $191.3 million for FY 2024. The decrease for FY 2025 reflects an impairment charge of $63.8 million in Q2 2024, which was primarily related to the write off of remaining goodwill for MVE. Excluding the impairment charge, non-GAAP adjusted operating costs and expenses for FY 2025 were $119.9 million, compared to $127.5 million for FY 2024.Loss from Continuing OperationsLoss from continuing operations was $8.5 million for Q4 2025, compared to a loss of $17.2 million for Q4 2024. Loss from continuing operations for FY 2025 was $34.0 million compared to a loss of $104.7 million for FY 2024.Net Income (Loss) – including Discontinued OperationsNet loss for Q4 2025 was $11.6 million and net income for FY 2025 was $78.3 million, compared to net losses of $18.7 million and $114.8 million for the same periods in 2024, respectively. Net income for FY 2025 was primarily driven by the divestiture of our CRYOPDP specialty courier business during Q2 2025, which contributed $112.3 million, net of taxes, to income from discontinued operations.Net loss attributable to common stockholders for Q4 2025 was $13.6 million, or $0.27 per share. Net income attributable to common stockholders for FY 2025 was $70.3 million, or $1.40 per share. This compares to net losses attributable to common stockholders of $20.7 million, or $0.42 per share, and $122.8 million, or $2.49 per share, for Q4 2024 and FY 2024, respectively.Non-GAAP adjusted net loss was $34.0 million for FY 2025, compared to $69.5 million for FY 2024.Adjusted EBITDA from Continuing OperationsAdjusted EBITDA from continuing operations was a negative $1.4 million for Q4 2025, compared to a negative $2.9 million for Q4 2024. Adjusted EBITDA from continuing operations for FY 2025 was a negative $5.8 million, compared to a negative $17.8 million for FY 2024.Cash, Cash equivalents, and Short-Term InvestmentsCryoport held $411.2 million in cash, cash equivalents, and short-term investments as of December 31, 2025.Share Repurchase ProgramsDuring 2025, the Company purchased 1,340,608 shares of its common stock under its repurchase programs, at an average price of $7.45 per share, for an aggregate amount of $10.0 million. These shares were returned to the status of authorized but unissued shares of common stock. Following these repurchases, the Company had approximately $63.9 million in total repurchase authorization available under its remaining repurchase program.Guidance for Full-Year Fiscal 2026The Company provides full-year 2026 revenue guidance in the range of $190.0 million to $194.0 million. The Company's 2026 guidance is dependent on its current business and expectations, which may be impacted by, among other things, factors that are outside of our control, such as national economic factors, the global macroeconomic and geopolitical environment, supply chain constraints, inflationary pressures, any U.S. federal government shutdown, tariffs and other trade restrictions and/or the effects of foreign currency fluctuations, as well as the other factors described in the Company's filings with the Securities and Exchange Commission ("SEC"), including in the "Risk Factors" section of its most recently filed periodic reports on Form 10-K and Form 10-Q, as well as in its subsequent filings with the SEC. Note: All reconciliations of GAAP to adjusted (non-GAAP) figures above are detailed in the reconciliation tables included later in the press release.Additional InformationFurther information on Cryoport's financial results is included in the attached condensed consolidated balance sheets and statements of operations, and additional explanations of Cryoport's financial performance are provided in the Company's Annual Report on Form 10-K for the year ended December 31, 2025, which is expected to be filed with the SEC on March 6, 2026. Additionally, the full report will be available in the SEC Filings section of the Investor Relations section of Cryoport's website at www.cryoportinc.com.Earnings Conference Call InformationIMPORTANT INFORMATION: In addition to the earnings release, a document titled "Cryoport Fourth Quarter and Full Year 2025 in Review", providing a review of Cryoport's business update, will be issued at 4:05 p.m. ET on Tuesday, March 3, 2026. The document is designed to be read in advance of the questions and answers conference call and will be accessible at https://ir.cryoportinc.com/news-events/ir-calendar.Cryoport management will host a conference call at 5:00 p.m. ET on March 3, 2026. The conference call will be in the format of a questions and answers session and will address any queries investors have regarding the Company's reported results. A slide deck will accompany the call.Conference Call InformationDate:Tuesday, March 3, 2026Time:5:00 p.m. ETDial-in numbers:1-800-717-1738 (U.S.), 1-646-307-1865 (International)Confirmation code:Request the "Cryoport Call" or Conference ID: 1189463Live webcast:'Investor Relations' section at www.cryoportinc.com or click here. Please allow 10 minutes prior to the call to visit this site to download and install any necessary audio software.The questions and answers call will be recorded and available approximately three hours after completion of the live event in the Investor Relations section of the Company's website at www.cryoportinc.com for a limited time. To access the replay of the questions and answers click here. A dial-in replay of the call will also be available to those interested, until March 10, 2026. To access the replay, dial 1-844-512-2921 (United States) or 1-412-317-6671 (International) and enter replay entry code: 1189463#.About Cryoport, Inc.Cryoport, Inc. (Nasdaq: CYRX is a leading global provider of integrated, temperature-controlled supply chain solutions for the life sciences, with an emphasis on regenerative medicine. We support biopharmaceutical companies, contract manufacturers (CDMOs), contract research organizations (CROs), developers, and researchers with a comprehensive suite of services and products designed to minimize risk and maximize reliability across the temperature-controlled supply chain for the life sciences. Our integrated supply chain platform includes the Cryoportal® Logistics Management Platform, advanced temperature-controlled packaging, informatics, specialized biologistics, biostorage, bioservices, cryopreservation services, and cryogenic systems, which in varying combinations deliver end-to-end solutions that meet the rigorous demands of the life sciences. With innovation, regulatory compliance, and agility at our core, we are "Enabling the Future of Medicine™." Headquartered in Nashville, Tennessee, our company maintains a strong global presence with operations across the Americas, EMEA, and APAC.For more information, visit www.cryoportinc.com or follow via LinkedIn at https://www.linkedin.com/company/cryoportinc or @cryoport on X, formerly known as Twitter at https://x.com/cryoport for live updates.Forward-Looking Statements
Statements in this press release which are not purely historical, including statements regarding the Company's intentions, hopes, beliefs, expectations, representations, projections, plans or predictions of the future, are forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995. These forward-looking statements include, but are not limited to, those related to the Company's industry, business, long-term growth prospects, plans, strategies, acquisitions, future financial results and financial condition, such as the Company's outlook and guidance for full-year 2026 revenue and the related assumptions and factors expected to drive revenue, projected growth trends in the markets in which the Company operates, the Company's plans and expectations regarding the launch of new products and services, such as the expected timing and benefits of such products and services launches, the Company's expectations about future benefits of its acquisitions, and anticipated regulatory filings, approvals, label/geographic expansions or moves to earlier lines of treatment approved with respect to the products of the Company's clients. Forward-looking statements also include those related to the Company's expectations about future benefits relating to the CRYOPDP divestiture and strategic partnership with DHL (collectively, the "DHL Transaction"), the Company's plans regarding its Global Supply Chain Centers, including expected timing of future openings, the Company's plans and expectations relating to its strategic pivot to expand its global partnerships, and the Company's expectation of revenue contribution from IntegriCell's cryopreservation service centers throughout 2026. It is important to note that the Company's actual results could differ materially from those in any such forward-looking statements. Factors that could cause actual results to differ materially include, but are not limited to, risks and uncertainties associated with the effects of changing economic and geopolitical conditions, supply chain constraints, inflationary pressures, tariffs and other trade restrictions, foreign currency fluctuations, trends in the products markets, any U.S federal government shutdown, variations in the Company's cash flow, market acceptance risks, and technical development risks. Additional risks and uncertainties relating to the DHL Transaction include, but are not limited to, the risk that any disruption resulting from the DHL Transaction may adversely affect our businesses and business relationships, including with employees and suppliers. The Company's business could be affected by other factors discussed in the Company's SEC reports, including in the "Risk Factors" section of its most recently filed periodic reports on Form 10-K and Form 10-Q, as well as in its subsequent filings with the SEC. The forward-looking statements contained in this press release speak only as of the date hereof and the Company cautions investors not to place undue reliance on these forward-looking statements. Except as required by law, the Company disclaims any obligation and does not undertake to update or revise any forward-looking statements in this press release.Cryoport, Inc. and Subsidiaries
Condensed Consolidated Statements of Operations
Three Months Ended
December 31,
(unaudited)Years Ended
December 31,(in thousands, except share and per share data)2025202420252024Revenue
Life Sciences Services revenue$ 25,005$ 21,476$ 96,497$ 82,044Life Sciences Products revenue20,44519,97679,68074,725Total revenue45,45041,452176,177156,769Cost of revenue:
Cost of services revenue12,85910,98749,42943,564Cost of products revenue10,88010,97243,69443,548Total cost of revenue23,73921,95993,12387,112Gross margin21,71119,49383,05469,657Operating costs and expenses:
Selling, general and administrative27,27628,091102,819109,809Engineering and development4,4664,15517,04117,710Impairment loss---63,809Total operating costs and expenses:31,74232,246119,860191,328Loss from operations(10,031)(12,753)(36,806)(121,671)Other income (expense):
Investment income3,3571,4279,7989,895Interest expense(634)(578)(2,361)(3,977)Gain on extinguishment of debt, net---18,505Other income (expense), net(87)(5,402)(2,801)(7,101)Income (loss) before provision for income taxes(7,395)(17,306)(32,170)(104,349)Provision for income taxes(1,126)134(1,799)(359)Income (loss) from continuing operations$ (8,521)$ (17,172)$ (33,969)$ (104,708)Income (loss) from discontinued operations, net(3,123)(1,497)112,270(10,048)Net income (loss)$ (11,644)$ (18,669)$ 78,301$ (114,756)Paid-in-kind dividend on Series C convertible preferred stock(2,000)(2,000)(8,000)(8,000)Net income (loss) attributable to common stockholders$ (13,644)$ (20,669)$ 70,301$ (122,756)Net income (loss) per share attributable to common stockholders:
Basic$ (0.27)$ (0.42)$ 1.40$ (2.49)Weighted average common shares issued and outstanding:
Basic49,759,26449,616,80650,071,66549,349,624 Cryoport, Inc. and Subsidiaries
Condensed Consolidated Balance Sheets
December 31,
20252024(in thousands)
Current assets
Cash and cash equivalents$ 250,494$ 34,137Short-term investments160,714216,460Accounts receivable, net33,35925,304Inventories23,18821,476Prepaid expenses and other current assets8,4197,943Current assets held for sale-36,251Total current assets476,174341,571Property and equipment, net85,44880,013Operating lease right-of-use assets39,72039,920Intangible assets, net138,082147,927Goodwill22,40020,569Deposits2,0921,951Deferred tax assets1,073842Long-term assets held for sale-70,699 Total assets $ 764,989$ 703,492
Current liabilities
Accounts payable and other accrued expenses$ 15,283$ 15,895Accrued compensation and related expenses12,98011,209Deferred revenue9431,061Current portion of operating lease liabilities4,1333,399Current portion of finance lease liabilities422315Current portion of convertible senior notes, net185,09414,298Current portion of notes payable163143Current portion of contingent consideration-2,808Current liabilities held for sale-15,435Total current liabilities219,01864,563Convertible senior notes, net-183,919Notes payable, net1,0871,114Operating lease liabilities, net39,07838,551Finance lease liabilities, net741800Deferred tax liabilities1,354804Other long-term liabilities444295Contingent consideration, net6293,751Long-term liabilities held for sale-7,797 Total liabilities262,351301,594 Total stockholders' equity502,638401,898 Total liabilities and stockholders' equity$ 764,989$ 703,492Note Regarding Use of Non-GAAP Financial MeasuresTo supplement our financial statements, which are presented on the basis of U.S. generally accepted accounting principles (GAAP), the following non-GAAP measures of financial performance as defined in Regulation G of the Securities Exchange Act of 1934 are included in this release: adjusted operating costs and expenses, adjusted net loss, and adjusted EBITDA from continuing operations. Non-GAAP financial measures are not calculated in accordance with GAAP, are not based on any comprehensive set of accounting rules or principles and may be different from non-GAAP financial measures presented by other companies. Non-GAAP financial measures, including adjusted operating costs and expenses, adjusted net loss, and adjusted EBITDA from continuing operations, should not be considered as a substitute for, or superior to, measures of financial performance prepared in accordance with GAAP.Adjusted operating costs and expenses is defined as operating costs and expenses, excluding impairment losses, if any. Adjusted net loss is defined as net income (loss), excluding impairment losses, net gain on extinguishment of debt, and income (loss) from discontinued operations, including gain on sale, if any. Management believes these measures, when read in conjunction with, and as supplemental to, the corresponding GAAP financial measures, provide useful measures to investors of Cryoport's expenses and operating results, meaningful comparisons with historical results, and insight into Cryoport's operating performance.Adjusted EBITDA from continuing operations is defined as loss from continuing operations adjusted for net interest expense, income taxes, depreciation and amortization expense, stock-based compensation expense, acquisition and integration costs, cost reduction initiatives, investment income, unrealized loss on investments, foreign currency loss, net gain on extinguishment of debt, impairment loss, changes in fair value of contingent consideration and charges or gains resulting from non-recurring events, as applicable.Management believes that adjusted EBITDA from continuing operations provides a useful measure of Cryoport's operating results, a meaningful comparison with historical results and with the results of other companies, and insight into Cryoport's ongoing operating performance. Further, management and the Company's board of directors utilize adjusted EBITDA from continuing operations to gain a better understanding of Cryoport's comparative operating performance from period to period and as a basis for planning and forecasting future periods. Adjusted EBITDA from continuing operations is also a significant performance measure used by Cryoport in connection with its incentive compensation programs. Management believes adjusted EBITDA from continuing operations, when read in conjunction with Cryoport's GAAP financials, is useful to investors because it provides a basis for meaningful period-to-period comparisons of Cryoport's ongoing operating results, including results of operations, against investor and analyst financial models, helps identify trends in Cryoport's underlying business and in performing related trend analyses, and it provides a better understanding of how management plans and measures Cryoport's underlying business.Cryoport, Inc. and Subsidiaries
Reconciliation of GAAP operating cost and expenses to Non-GAAP adjusted operating cost and expenses
Three Months Ended
December 31,
(unaudited)Years Ended
December 31,
2025202420252024(in thousands)
GAAP operating costs and expenses$ 31,742$ 32,246$ 119,860$ 191,328Non-GAAP adjustments to operating costs and expenses
Impairment loss———(63,809)Non-GAAP adjusted operating costs and expenses$ 31,742$ 32,246$ 119,860$ 127,519
Cryoport, Inc. and Subsidiaries
Reconciliation of GAAP net income (loss) to Non-GAAP adjusted net income (loss)
Three Months Ended
December 31,
(unaudited)Years Ended
December 31,
2025202420252024(in thousands)
GAAP net income (loss)$ (11,644)$ (18,670)$ 78,301$ (114,756)Non-GAAP adjustments to net income (loss)
Income (loss) from discontinued operations, including gain on sale(3,123)—112,270—Gain on extinguishment of debt, net———18,505Impairment loss———(63,809)Non-GAAP adjusted net loss$ (8,521)$ (18,670)$ (33,969)$ (69,452) Cryoport, Inc. and Subsidiaries
Reconciliation of GAAP loss from continuing operations to adjusted EBITDA
(unaudited)
Three Months Ended
December 31,Years Ended
December 31,
2025202420252024(in thousands)
GAAP loss from continuing operations$ (8,521)$ (17,172)$ (33,969)$ (104,708)Non-GAAP adjustments to loss:
Depreciation and amortization expense6,3555,99225,15323,565Acquisition and integration costs6375655Cost reduction initiatives—310642842Investment income(3,357)(1,427)(9,798)(9,895)Unrealized loss on investments822,4457025,038Foreign currency loss2483,1302,7692,352Interest expense, net6345792,3613,977Stock-based compensation expense2,4313,64410,06616,567Gain on extinguishment of debt, net———(18,505)Impairment loss———63,809Change in fair value of contingent consideration—(225)(5,178)(1,827)Income taxes1,126(134)1,799359Other adjustments(401)—(401)—Adjusted EBITDA from continuing operations$ (1,397)$ (2,855)$ (5,779)$ (17,771)
View original content to download multimedia:https://www.prnewswire.com/news-releases/cryoport-reports-fourth-quarter-and-full-year-2025-financial-results-302703027.htmlSOURCE Cryoport, Inc.
Original: Cryoport Reports Fourth Quarter and Full-Year 2025 Financial Results