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| 日付 | 保有者名 | 取引株数 | 金額レンジ ($) | 取引種別 | 価格レンジ ($) | 届出終了時の株数 | % 変化 |
|---|---|---|---|---|---|---|---|
| 2026-04-09 | Dr. Gregory GeorgeNon-Independent Non-Executive Director | 70.00k | 109.89k | 買い | 1.57 | 25.91M | 0.27% |
| 2026-04-09 | Dr. Gregory GeorgeNon-Independent Non-Executive Director | 7.21M | 11.32M | 買い | 1.57 | 12.86M | 127.76% |
| 2025-11-06 | State Street Global Advisors, Inc.法人 | 1.04M | 26.61k | 買い | 1.42 - 2.15 | 67.01M | 1.58% |
| 2025-11-11 | State Street Global Advisors, Inc.法人 | -1.22M | 0.00 | 売り | 1.57 - 2.04 | 67.01M | -1.78% |
| 2025-11-06 | State Street Global Advisors, Inc.法人 | -39.83M | 0.00 | Other Disposition | - | 67.01M | -37.28% |
| 2026-03-03 | Dr. Gregory GeorgeNon-Independent Non-Executive Director | 5.99M | 9.36M | 買い | 1.02 - 9.93 | 147.80M | 4.22% |
| 2026-03-04 | James Georgeインサイダー | 200.00k | 2.14M | 買い | 10.31 - 10.83 | 8.00M | 2.56% |
| 2026-01-22 | JPMorgan Chase & Co.法人 | -28.20k | 0.00 | Other Disposition | - | 46.31M | -0.06% |
| 2026-01-23 | JPMorgan Chase & Co.法人 | 902.80k | 1.61M | 買い | 1.72 - 1.91 | 18.16M | 5.23% |
| 2026-01-23 | JPMorgan Chase & Co.法人 | -1.19M | 2.16M | 売り | 1.72 - 1.91 | 18.16M | -6.17% |
| 2026-01-29 | JPMorgan Chase & Co.法人 | -1.17M | 4.27k | Other Disposition | 1.78 | 18.16M | -6.05% |
| 2026-01-22 | JPMorgan Chase & Co.法人 | -5.72M | 0.00 | Other Disposition | - | 44.00M | -11.51% |
| 2026-01-22 | JPMorgan Chase & Co.法人 | 259.86k | 467.93k | 買い | 1.80 - 1.82 | 18.32M | 1.44% |
| 2026-01-22 | JPMorgan Chase & Co.法人 | -70.85k | 123.77k | 売り | 1.71 - 1.82 | 18.32M | -0.39% |
| 2026-01-22 | JPMorgan Chase & Co.法人 | -140.58k | 0.00 | Other Disposition | - | 18.32M | -0.76% |
| 2025-12-19 | JP Morgan Asset Management法人 | 438.37k | 838.27k | 買い | 1.91 | 718.50k | 156.49% |
| 2026-01-13 | JP Morgan Asset Management法人 | -16.07k | 29.23k | 売り | 1.81 - 1.82 | 718.50k | -2.19% |
| 2025-12-17 | JPMorgan Chase & Co.法人 | -7.31M | 0.00 | Other Disposition | - | 49.60M | -12.84% |
| 2025-12-17 | JPMorgan Chase & Co.法人 | 3.11M | 5.91M | 買い | 1.68 - 2.23 | 18.13M | 20.70% |
| 2025-12-17 | JPMorgan Chase & Co.法人 | -3.09M | 5.85M | 売り | 1.68 - 2.13 | 18.13M | -14.55% |
| 2026-01-02 | JPMorgan Chase & Co.法人 | -1.50M | 0.00 | Other Disposition | - | 18.13M | -7.65% |
| 2026-01-06 | Dr. Eric A. RoseChief Medical Officer & Executive Director | 1.28M | 8.55k | Derivative Exercise and Retained Stock | 0.01 | 6.68M | 23.73% |
| 2026-01-06 | Dr. Eric A. RoseChief Medical Officer & Executive Director | -638.67k | 1.26M | 売り | 1.98 | 6.68M | -8.73% |
| 2026-01-09 | Ms. Lynette Elizabeth CobleyIndependent Non-Executive Director | 30.00k | 64.11k | 買い | 2.14 | 63.00k | 90.91% |
| 2026-01-06 | Dr. Gregory GeorgeNon-Independent Non-Executive Director | -2.40M | 0.00 | Other Derivative Disposition | - | - | - |
| 2025-12-15 | JPMorgan Chase & Co.法人 | -12.65M | 0.00 | Other Disposition | - | 35.74M | -26.15% |
| 2025-12-15 | JPMorgan Chase & Co.法人 | 489.99k | 887.99k | 買い | 1.81 - 1.84 | 16.67M | 3.03% |
| 2025-12-15 | JPMorgan Chase & Co.法人 | -357.43k | 656.12k | 売り | 1.81 - 1.84 | 16.67M | -2.10% |
| 2025-12-15 | JPMorgan Chase & Co.法人 | -2.97M | 0.00 | Other Disposition | - | 16.67M | -15.14% |
| 2025-11-20 | JP Morgan Asset Management法人 | -24.80k | 40.48k | 売り | 1.51 - 1.77 | 293.53k | -7.79% |
| 2025-10-14 | JPMorgan Chase & Co.法人 | -30.17M | 0.00 | Other Disposition | - | 46.61M | -39.29% |
| 2025-10-13 | JPMorgan Chase & Co.法人 | 4.74M | 8.00M | 買い | 1.47 - 1.99 | 18.06M | 35.62% |
| 2025-10-13 | JPMorgan Chase & Co.法人 | -4.03M | 6.80M | 売り | 1.47 - 1.93 | 18.06M | -18.23% |
| 2025-10-14 | JPMorgan Chase & Co.法人 | -14.90M | 0.00 | Other Disposition | - | 18.06M | -45.20% |
| 2025-12-08 | State Street Global Advisors, Inc.法人 | -3.25M | 0.00 | Other Disposition | - | 10.28M | -24.01% |
| 2025-11-26 | State Street Global Advisors, Inc.法人 | -6.47M | 0.00 | Other Disposition | - | 62.65M | -9.36% |
| 2025-10-28 | State Street Global Advisors, Inc.法人 | -14.28M | 1.04M | Other Disposition | 1.49 - 1.62 | 63.36M | -18.40% |
| 2025-10-24 | State Street Global Advisors, Inc.法人 | 9.95k | 16.65k | 買い | 1.67 | 52.93M | 0.02% |
| 2025-10-22 | State Street Global Advisors, Inc.法人 | -14.16k | 24.83k | 売り | 1.75 | 52.93M | -0.03% |
| 2025-10-23 | State Street Global Advisors, Inc.法人 | -1.38M | 0.00 | Other Disposition | - | 52.93M | -2.54% |
| 2025-10-21 | Mr. William M. BurnsIndependent Non-Executive Vice Chair | 120.00k | 102.09k | Derivative Exercise and Retained Stock | 0.85 | 226.25k | 112.94% |
| 2025-10-21 | State Street Global Advisors, Inc.法人 | -927.13k | 4.03k | Other Disposition | 1.89 | 55.71M | -1.64% |
| 2025-09-19 | State Street Global Advisors, Inc.法人 | 238.20k | 1.27k | 買い | 1.54 - 1.84 | 63.80M | 0.37% |
| 2025-09-19 | State Street Global Advisors, Inc.法人 | -2.84M | 0.00 | 売り | 1.54 - 1.92 | 63.80M | -4.26% |
| 2025-09-19 | State Street Global Advisors, Inc.法人 | -9.81M | 0.00 | Other Disposition | - | 63.80M | -13.32% |
| 2025-08-28 | JP Morgan Asset Management法人 | -147.08k | 228.56k | 売り | 1.31 - 1.97 | 999.83k | -12.82% |
| 2025-07-23 | JPMorgan Chase & Co.法人 | -45.56M | 0.00 | Other Disposition | - | 45.90M | -49.82% |
| 2025-07-23 | JPMorgan Chase & Co.法人 | 10.79M | 17.09M | 買い | 1.38 - 1.97 | 17.99M | 149.92% |
| 2025-07-23 | JPMorgan Chase & Co.法人 | -9.51M | 15.08M | 売り | 1.31 - 1.97 | 17.99M | -34.59% |
| 2025-07-25 | JPMorgan Chase & Co.法人 | -12.85M | 15.34k | Other Disposition | 0.31 | 17.99M | -41.66% |
| 2025-10-10 | JP Morgan Asset Management法人 | -681.50k | 0.00 | Other Disposition | - | 318.34k | -68.16% |
| 2025-10-10 | JPMorgan Chase & Co.法人 | -19.49k | 0.00 | Other Disposition | - | 45.88M | -0.04% |
| 2025-10-10 | JPMorgan Chase & Co.法人 | 8.45k | 15.93k | 買い | 1.88 - 1.89 | 18.06M | 0.05% |
| 2025-10-10 | JPMorgan Chase & Co.法人 | -116.60k | 219.87k | 売り | 1.84 - 1.93 | 18.06M | -0.64% |
| 2025-10-08 | Dr. Eric A. RoseChief Medical Officer & Executive Director | -120.00k | 128.83k | Derivative Exercise and Sale | 0.86 - 1.94 | 6.04M | - |
| 2025-09-15 | State Street Global Advisors, Inc.法人 | -1.45M | 0.00 | Other Disposition | 1.55 - 1.56 | 63.13M | -2.25% |
| 2025-09-12 | State Street Global Advisors, Inc.法人 | 3.00k | 4.40k | 買い | 1.47 | 9.93M | 0.03% |
| 2025-09-12 | State Street Global Advisors, Inc.法人 | -247.37k | 0.00 | Other Disposition | - | 9.93M | -2.43% |
| 2025-05-22 | Dr. William Gueckインサイダー | 4.28M | 47.20M | 買い | 1.09 - 20.64 | 62.38M | 7.36% |
| 2025-08-28 | State Street Global Advisors, Inc.法人 | -11.07M | 0.00 | Other Disposition | 1.41 - 1.54 | 63.45M | -14.85% |
| 2025-09-05 | Dr. Gregory GeorgeNon-Independent Non-Executive Director | 325.90k | 4.76M | 買い | 14.61 | 22.15M | 1.49% |
| 2025-09-05 | Dr. Gregory GeorgeNon-Independent Non-Executive Director | 9.64M | 14.09M | 買い | 1.46 | 33.54M | 40.33% |
| 2025-08-22 | State Street Global Advisors, Inc.法人 | 178.44k | 283.52k | 買い | 1.55 - 1.62 | 58.00M | 0.31% |
| 2025-08-22 | State Street Global Advisors, Inc.法人 | -57.34k | 0.00 | Other Disposition | - | 58.00M | -0.10% |
| 2025-07-28 | State Street Global Advisors, Inc.法人 | -4.24M | 11.14k | Other Disposition | 1.49 - 1.60 | 62.73M | -6.34% |
| 2025-07-23 | State Street Global Advisors, Inc.法人 | 6.45k | 10.33k | 買い | 1.57 - 1.65 | 57.70M | 0.01% |
| 2025-07-24 | State Street Global Advisors, Inc.法人 | -24.89k | 42.42k | 売り | 1.70 | 57.70M | -0.04% |
| 2025-07-24 | State Street Global Advisors, Inc.法人 | -114.00k | 0.00 | Other Disposition | - | 57.70M | -0.20% |
| 2025-02-06 | State Street Global Advisors, Inc.法人 | -22.63M | 271.64k | Other Disposition | 1.04 - 1.21 | 62.17M | -26.69% |
| 2025-07-21 | JPMorgan Chase & Co.法人 | -1.22M | 0.00 | Other Disposition | - | 40.88M | -2.91% |
| 2025-07-21 | JPMorgan Chase & Co.法人 | 125.94k | 189.81k | 買い | 1.49 - 1.51 | 19.79M | 0.64% |
| 2025-07-21 | JPMorgan Chase & Co.法人 | -474.42k | 716.17k | 売り | 1.46 - 1.58 | 19.79M | -2.34% |
| 2025-07-21 | JPMorgan Chase & Co.法人 | -3.84M | 0.00 | Other Disposition | - | 19.79M | -16.23% |
| 2025-07-17 | JPMorgan Chase & Co.法人 | 694.67k | 1.04M | 買い | 1.12 - 1.57 | 23.87M | 3.00% |
| 2025-07-17 | JPMorgan Chase & Co.法人 | -466.84k | 692.03k | 売り | 1.12 - 1.60 | 23.87M | -1.92% |
| 2025-07-17 | JPMorgan Chase & Co.法人 | -1.25M | 0.00 | Other Disposition | - | 23.87M | -4.99% |
| 2025-07-16 | JPMorgan Chase & Co.法人 | -155.87k | 0.00 | Other Disposition | - | 39.52M | -0.39% |
| 2025-07-16 | JPMorgan Chase & Co.法人 | -96.50k | 15.17k | Other Disposition | 1.11 - 1.14 | 23.83M | -0.40% |
| 2025-07-07 | JPMorgan Chase & Co.法人 | -7.22M | 0.00 | Other Disposition | - | 39.67M | -15.40% |
| 2025-07-07 | JPMorgan Chase & Co.法人 | 556.03k | 589.64k | 買い | 1.01 - 1.12 | 23.89M | 2.38% |
| 2025-07-07 | JPMorgan Chase & Co.法人 | -438.04k | 455.62k | 売り | 1.02 - 1.12 | 23.89M | -1.80% |
| 2025-07-08 | JPMorgan Chase & Co.法人 | -915.26k | 639.09 | Other Disposition | 1.08 - 1.11 | 23.89M | -3.69% |
| 2025-07-03 | JPMorgan Chase & Co.法人 | -11.60M | 0.00 | Other Disposition | - | 34.50M | -25.17% |
| 2025-07-03 | JPMorgan Chase & Co.法人 | 82.96k | 89.11k | 買い | 1.06 - 1.08 | 23.29M | 0.36% |
| 2025-07-03 | JPMorgan Chase & Co.法人 | -3.59k | 3.87k | 売り | 1.08 | 23.29M | -0.02% |
| 2025-07-03 | JPMorgan Chase & Co.法人 | -71.72k | 70.80k | Other Disposition | 1.06 - 1.10 | 23.29M | -0.31% |
| 2025-06-24 | JPMorgan Chase & Co.法人 | -3.30M | 0.00 | Other Disposition | - | 45.45M | -6.78% |
| 2025-06-24 | JPMorgan Chase & Co.法人 | 849.43k | 903.38k | 買い | 1.04 - 1.21 | 22.41M | 3.94% |
| 2025-06-24 | JPMorgan Chase & Co.法人 | -458.82k | 496.34k | 売り | 1.03 - 1.21 | 22.41M | -2.01% |
| 2025-06-19 | JPMorgan Chase & Co.法人 | 465.42k | 546.67k | 買い | 1.17 | 36.91M | 1.28% |
| 2025-06-16 | JPMorgan Chase & Co.法人 | -5.00M | 0.00 | Other Disposition | - | 36.91M | -11.92% |
| 2025-06-13 | JPMorgan Chase & Co.法人 | 481.44k | 540.94k | 買い | 1.00 - 1.23 | 26.73M | 1.83% |
| 2025-06-13 | JPMorgan Chase & Co.法人 | -407.96k | 468.96k | 売り | 1.00 - 1.22 | 26.73M | -1.50% |
| 2025-06-13 | JPMorgan Chase & Co.法人 | -1.20M | 0.00 | Other Disposition | - | 26.73M | -4.31% |
| 2025-06-03 | The Vanguard Group, Inc.法人 | 79.11k | 94.30k | 買い | 1.06 - 1.22 | 63.45M | 0.12% |
| 2025-06-12 | The Vanguard Group, Inc.法人 | -566.82k | 687.45k | 売り | 1.17 - 1.21 | 63.45M | -0.89% |
| 2025-06-12 | JPMorgan Chase & Co.法人 | -168.91k | 0.00 | Other Disposition | - | 36.82M | -0.46% |
| 2025-06-12 | JPMorgan Chase & Co.法人 | 329.78k | 399.66k | 買い | 1.18 - 1.22 | 27.79M | 1.20% |
| 2025-06-12 | JPMorgan Chase & Co.法人 | -9.26k | 10.91k | 売り | 1.17 - 1.20 | 27.79M | -0.03% |
| 2025-06-12 | JPMorgan Chase & Co.法人 | -380.60k | 0.00 | Other Disposition | - | 27.79M | -1.35% |
| 2025-06-03 | JPMorgan Chase & Co.法人 | 475.76k | 549.79k | 買い | 1.05 - 1.24 | 26.82M | 1.81% |
| 2025-06-03 | JPMorgan Chase & Co.法人 | -404.82k | 467.60k | 売り | 1.05 - 1.25 | 26.82M | -1.49% |
| 2025-06-03 | JPMorgan Chase & Co.法人 | -11.62M | 88.89k | Other Disposition | 1.13 - 1.27 | 26.82M | -30.23% |
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