Tempest Therpeutics Inc (TPST)

Anyone get the warrants yet?

The distribution of the Warrant Dividends is expected to be Tuesday, February 3, 2026, but is subject to the prior satisfaction of closing conditions for the transactions contemplated by the Asset Purchase Agreement (the “Closing Conditions”), including receipt of stockholder approval of Proposal 5 contained in Tempest’s definitive proxy statement on Schedule 14A, filed with the Securities and Exchange Commission on December 31, 2025 (“Stockholder Approval”).

$4.04 small volume erratic pump dump

$3.62

$3.52

“The Proposed Transaction will result in an even more diversified portfolio that we believe provides stockholders with new opportunity for value creation and patients with new potential therapies,” said Stephen Brady, president and chief executive officer of Tempest. “With the new funding support, Tempest has increased its opportunity to realize potential value creating milestones in the midst of this prolonged challenging market.”Dr. Angel added, “I echo Steve’s sentiments and share in the vision to bring innovative therapies to patients with cancer. I believe there is significant potential to be realized in combining these programs and look forward to working with the Tempest team to bring these programs forward for the benefit of patients.”Combined Pipeline
Matt Angel, Ph.D.Dr. Matt Angel is an experienced biotechnology executive with expertise in leading lean cell therapy companies. Dr. Angel led Brooklyn Immunotherapeutics (Nasdaq: BTX) as CEO from 2022-2023, successfully restructuring the company and extending the company’s runway in a challenging market environment. Dr. Angel has led Factor Bioscience Inc. as co-founder and CEO since 2011 and is co-founder of cell therapy companies Novellus Therapeutics (founded 2014; sold 2021) and Exacis Biotherapeutics (founded 2020; sold 2023). Dr. Angel has deep expertise in cell therapy development and intellectual property protection and licensing. Dr. Angel is also experienced in assembling and managing multidisciplinary teams. A pioneer in cell engineering technology, Dr. Angel is a prolific inventor with more than 150 patents covering mRNA, nucleic acid delivery, gene editing, and cell reprogramming technologies. Dr. Angel received his Ph.D. from the Massachusetts Institute of Technology, where he published seminal discoveries in the then-nascent field of mRNA.Approvals and TimingThe board of directors of Tempest has unanimously approved the Proposed Transaction and intends to recommend that Tempest stockholders vote to adopt the asset purchase agreement and the related issuance of Common Stock with respect to the Proposed Transaction at a meeting of stockholders.The Proposed Transaction is conditioned upon approval of the holders of a majority of the outstanding shares of Common Stock of Tempest entitled to vote to adopt the asset purchase agreement with respect to the Proposed Transaction.Completion of the transaction is expected in early 2026, subject to the approval of Tempest stockholders and the satisfaction of other customary closing conditions.AdvisorsMTS Health Partners, L.P. is serving as financial advisor to Tempest, and Cooley LLP is serving as legal advisor. In addition, MTS Securities, LLC (an affiliate of MTS Health Partners, L.P.) provided an opinion to the board of directors of Tempest regarding the fairness of the purchase price to be paid by Tempest to Factor in connection with the Proposed Transaction, subject to the qualifications and limitations set forth therein.About Tempest TherapeuticsTempest Therapeutics is a clinical-stage biotechnology company with a diverse portfolio of small molecule product candidates containing tumor-targeted and/or immune-mediated mechanisms with the potential to treat a wide range of tumors. The company’s novel programs range from early research to later-stage investigation in a randomized global study in first-line cancer patients. Tempest is headquartered in Brisbane, California. More information abou

Tempest Announces Strategic Acquisition of New Dual-CAR T Programs from Factor with Simultaneous Runway Extension Projected to Mid 2027November 19 2025 - 9:00AM
http://www.facebook.com/sharer.php?s=100&p[url]=https%3A%2F%2Finvestorshub.advfn.com%2Fstock-market%2FNASDAQ%2Ftempest-therpeutics-TPST%2Fstock-news%2F97275356%2Ftempest-announces-strategic-acquisition-of-new-dua
In a transaction designed to both expand its pipeline and extend its runway, Tempest Therapeutics, Inc. (Nasdaq: TPST) (“Tempest” or “the Company”), a clinical-stage biotechnology company with a pipeline of targeted and immune-mediated therapeutics to fight cancer, today announced that it has entered into definitive agreements to acquire certain dual-targeting chimeric antigen receptor (CAR)-T programs from Factor Bioscience Inc. and its affiliates (collectively, “Factor”) in an all-stock transaction (the “Proposed Transaction”). The Proposed Transaction is expected to close in early 2026, subject to necessary stockholder approvals and satisfaction of closing conditions (the “Closing”).The Proposed Transaction will expand and further diversify Tempest’s existing clinical-stage pipeline, with the acquisition of the first clinical-stage CD19/BCMA parallel structured dual-CAR T specifically designed to target patients with extramedullary disease (EMD), which we are referring to as TPST-2003. In addition, the Company expects that existing cash at Closing and an investment commitment from Factor will support the Company’s planned operations to mid 2027, including through potential key development and data milestones in 2026 and 2027.Key Takeaways:

gonna moon soon

I am no longer in TPST...🥳

Things are looking good here?

Lotsa smoke today about buyout, is there fire?

I’m new to this company and then at early stages of DD. Analyst forecasts to be strong, but it sure has had a fall from Grace. I also saw some questioning about potential reverse split. Any insight would be greatly appreciated.

Where are we all thinking with recent ODA and RS talk?

Tempest Receives Orphan Drug Designation from the U.S. Food and Drug Administration for Amezalpat to Treat Patients with Hepatocellular Carcinoma (HCC)

Source: GlobeNewswire Inc.

Tempest Therapeutics, Inc. (Nasdaq: TPST), a clinical-stage biotechnology company developing first-in-class1 targeted and immune-mediated therapeutics to fight cancer, today announced that the U.S. Food and Drug Administration (FDA) has granted Orphan Drug Designation (ODD) to amezalpat (TPST-1120), an oral, small molecule, selective PPAR? antagonist for the treatment of patients with hepatocellular carcinoma (HCC).
“Receiving orphan drug designation for amezalpat to treat HCC underscores the critical need for new treatment options for patients suffering from this historically hard to treat disease,” said Sam Whiting, M.D., Ph.D., chief medical officer and head of R&D of Tempest. “Tempest is dedicated to developing groundbreaking cancer treatments that will improve patients’ lives, and with broad agreement in hand from both the FDA and EMA, the team continues to prepare for a pivotal phase 3 study for amezalpat in first-line HCC patients.”

This important regulatory designation follows positive data across multiple key study efficacy and safety endpoints in a global randomized Phase 1b/2 clinical study evaluating amezalpat plus standard-of-care atezolizumab and bevacizumab versus atezolizumab and bevacizumab alone in the first-line treatment of patients with unresectable or metastatic HCC. Notable positive outcomes of the randomized comparison include a six-month improvement in median overall survival (OS) with a hazard ratio (HR) of 0.65 for patients receiving the amezalpat combination therapy and an objective response rate (ORR) of 30% vs 13% favoring the amezalpat arm. In addition, survival benefit from the addition of amezalpat was preserved in key sub-populations including PD-L1 negative disease and b-catenin mutated disease, which is consistent with amezalpat’s proposed mechanism of action to target both the tumor cells directly and the patient’s immune system.

It's in the filings...🥳

Do you still think R/S is coming....

TPST...$1.09...🥳...BRISBANE, Calif., Nov. 12, 2024 (GLOBE NEWSWIRE) -- Tempest Therapeutics, Inc. (Nasdaq: TPST), a clinical-stage biotechnology company developing first-in-classi targeted and immune-mediated therapeutics to fight cancer, today announced that the company received a “Study May Proceed” letter from the U.S. Food and Drug Administration (FDA) to evaluate amezalpat (TPST-1120) in combination with atezolizumab and bevacizumab, the current standard of care, versus the standard of care alone in a pivotal randomized Phase 3 trial for the first-line treatment of unresectable or metastatic hepatocellular carcinoma (HCC).

“The clinical and regulatory team at Tempest are thrilled to receive this notice from FDA with respect to the planned pivotal Phase 3 trial to evaluate amezalpat as a potential treatment for first-line liver cancer,” said Sam Whiting M.D., Ph.D., chief medical officer and head of R&D of Tempest. “Previously reported positive Phase 2 data underscore amezalpat’s potential to improve the survival of patients facing this life-threatening disease, and our team is dedicated to advancing the program and bringing amezalpat to patients.”

georgie18

Member Level
Re: None

Friday, November 08, 2024 6:22:34 PM

Post#
664322
of 664538
TPST...$1.09...Chart firming up from the .85 Range Bottom...R/S coming here...🥳

I sold my shares, but kept the calls.

TPST...$1.09...Chart firming up from the .85 Range Bottom...R/S coming here...🥳

Not a bad recovery. Will see if an ER or business report is released, then decide to sell or not.

TPST , new 52 week low

Agreed, we will see positive news and a boost in price prior to the split..... the higher the price the lower the split IF its even required. Should they get positive news and more support from ROCHE this can rocket and then cancel split... that's moon time!

We shall see...🥳

1 to 2, or 1 to 15 RS. The split doesn't make sense unless a notable event is coming. Negative sentiment will simply beat it down, and kill existing holders further.

I'm under the impression dilution is coming.

Yes I did...will buy back when the dust settles...🥳...made great profit with TPST and if the reverse should happen it should put this stock in the $40...imo...we shall see...

Did you sell on the 14a news?

You saw the 14a...🥳

aDDed after hours sub $1 range...

RS was unexpected for something without a delisting notice. Perhaps something planned to prevent a takeover. Hmm...

TPST...14A Filing...Approval of a series of alternate amendments to our Restated Certificate of Incorporation to effect, at the option of our Board of Directors, a reverse stock split of our common stock at a ratio in the range of 1-for-2 to 1-for-15, inclusive, with such ratio to be determined by our Board of Directors in its sole discretion (“Reverse Stock Split Proposal” or “Proposal 1”).
What if another matter is properly brought before the Special Meeting?

TPST....85...A/H Dip...🥳

Nice to have you with me on it...🥳

One of your GM favorites been adding myself low $1s for next blastoff to $2s ...newsand trials

TPST...$1.16s in the P/M...🥳

georgie18

Member Level
Re: georgie18 post# 614

Friday, October 25, 2024 12:38:28 PM

Post#
615
of 617
TPST...$1.12s clearing here...🥳Reversing...

georgie18

Member Level
Re: georgie18 post# 662364

Friday, October 25, 2024 9:43:40 AM

Post#
662715
of 662771
TPST...$1.08...Big Block Buys hitting here...🥳

georgie18

Member Level
Re: None

Wednesday, October 23, 2024 8:55:30 AM

Post#
613
of 613
TPST...Loaded $1.03 to $1.05s...🥳

Long hold. Roche wouldn't supply them with goods if they felt phase 3 would fail. Looking for $2 on positive results.

Have a Great Weekend Y'all...🥳

TPST...$1.12s clearing here...🥳Reversing...

georgie18

Member Level
Re: georgie18 post# 662364

Friday, October 25, 2024 9:43:40 AM

Post#
662715
of 662771
TPST...$1.08...Big Block Buys hitting here...🥳

georgie18

Member Level
Re: None

Wednesday, October 23, 2024 8:55:30 AM

Post#
613
of 613
TPST...Loaded $1.03 to $1.05s...🥳

TPST...$1.08...Big Block Buys hitting here...🥳

georgie18

Member Level
Re: None

Wednesday, October 23, 2024 8:55:30 AM

Post#
613
of 613
TPST...Loaded $1.03 to $1.05s...🥳

TPST...Loaded $1.03 to $1.05s...🥳

May be an AH show after all

Yup TPST! I have RNAZ on list too. Buying both with next check. 🔥

TPST...$1.22...🥳...Dipping it to fill the Open Gap...another great add spot...Ran to $1.60 range in the A/H ...

georgie18

Member Level
Re: georgie18 post# 384329

Tuesday, October 15, 2024 3:37:36 PM

Post#
384411
of 384426
TPST...$1.14clearing here...🥳

georgie18

Member Level
Re: None

Friday, October 11, 2024 9:46:27 AM

Post#
603
of 603
TPST...99...great add spot....🥳

TPST …yes beauty move in the A/H…🥳

I’m in!

TPST smell green dude!!! RNAZ Next DRUG

Nice Georgie… TPST $1.61 after hours close…

The next DRUG?!

TPST...$1.14clearing here...🥳

georgie18

Member Level
Re: None

Friday, October 11, 2024 9:46:27 AM

Post#
603
of 603
TPST...99...great add spot....🥳

TPST...99...great add spot....🥳

TPST: Nope!! Cancer is NOT trending anymore, CLOWN!!! (Nice call, IDIOT!!!)

TPST...$1.09...Great add opportunity...imo...we shall see...🥳