RNS Number:6412K
CeNeS Pharmaceuticals PLC
01 May 2003



                   CeNeS Pharmaceuticals plc ("the Company")

                               Holding in Company


The Company was today informed by Dr. D. Roach that, following a purchase of
1,500,000 ordinary shares of 10p each in the Company ("Ordinary Shares") today
was interested in 11,911,704 Ordinary Shares, representing approximately 6.8 per
cent. of the issued share capital of the Company. This holding is registered in
the name of Dr. D. Roach.

4,638,176 of these Ordinary Shares are held by ATM Global Investments, a company
of which Daniel Roach is a director.


1 May 2003


                      This information is provided by RNS
            The company news service from the London Stock Exchange

END
HOLUASVROORVRAR