KYOCERA Honored by Japan's METI for Aquala® Artificial Hip Joint Technology
2018年6月25日 - 10:04PM
ビジネスワイヤ(英語)
Kyocera Corporation (NYSE:KYO)(TOKYO:6971) today announced that
its innovative Aquala technology received Japan’s “Prize of the
Minister of Economy, Trade and Industry” during the 2018 National
Invention Awards held in Tokyo June 12 by the Japan Institute of
Invention and Innovation (JIII).
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Aquala(R) Technology (Graphic: Business
Wire)
The honor recognizes Kyocera’s Aquala surface-processing
technology (Japan Patent No. 4963838), which has been demonstrated
to extend the life expectancy of artificial hip joints, and was
developed in collaboration with The University of Tokyo. The JIII
award program was created in 1919 to recognize original inventions
showing excellent future promise.
Artificial hip joints have become a common treatment for
hip-joint diseases such as osteoarthritis and certain hip
fractures. The artificial joint replaces a portion of the patient’s
femur known as the femoral head and its mating surface on the
patient’s pelvis, known as the acetabulum. Kyocera developed its
Aquala technology to create an exceptionally low-friction bearing
surface on the acetabular side of the joint, which couples with
diamond-polished ceramic on the femoral side. Kyocera’s Aquala
technology represents the first Japan-market use*1 of the
biocompatible material PMPC*2 to create a nanometer-scale
hydrophilic polymer layer with functions similar to human articular
cartilage in the implant’s acetabular liner.
Aquala technology is designed to reduce the incidence of wear
particles produced at the bearing surface of the artificial joint —
which can otherwise lead to peripheral inflammation, loosening of
the joint and eventual joint failure. Surgeons have implanted
approximately 45,000 total hip replacements using Kyocera’s Aquala
technology since it was approved by Japan’s Ministry of Health,
Labor and Welfare in 2011.
Development BackgroundJoint dysfunction from disease or
injury can cause debilitating pain and lost mobility. Current
methods of Total Hip Arthroplasty (THA) have been in practice more
than 50 years, with approximately 130,000 such surgeries last year
in Japan alone and about 1.8 million worldwide – figures expected
to grow as populations age. One of the main limitations of this
procedure is the service life of the artificial hip joint, which is
generally recognized as about 20 years. Today’s lifestyle and
activity factors are resulting in younger THA candidates with
longer life expectancies — and a second THA on the same joint tends
to be more challenging.
In 2001, Kyocera began collaborating with The University of
Tokyo to develop artificial hip joints that would experience less
wear over a longer lifetime. Their goal was to reduce or eliminate
the cycle of wear, peripheral inflammation, loosening of the
implant and premature failure caused by microscopic “wear debris”
that accumulates over the years around implants made of
conventional materials. The development team utilized biomimetic
research*3 to create a hydrophilic nano-surface treatment*4 on a
biocompatible polymer as the bearing surface of the hip joint. By
successfully modeling the surface structure of human articular
cartilage, they developed a wear-resisting technology that reduces
these wear particles by 99 percent.
Physical loads produced by walking can exert several times a
person’s body weight on the hip joints. By reducing wear debris 99
percent, Kyocera’s Aquala technology is expected to contribute to a
longer service life for the hip implant as compared to conventional
implants. This expectation is supported by Kyocera’s own walking
load simulation tests, which replicate 15 years of patient use.
Subsequent research has shown extremely low wear even after
long-term testing equivalent to 70 years in vivo*5.
Aquala® Technology Prior
Awards
2011 Engineering Award presented by Japanese Society for
Artificial Organs 2011 25th Cutting-Edge Engineering Award for
pioneering originality presented by the Minister of Economy, Trade
and Industry 2012 Engineering Award presented by Japanese Society
for Biomaterials 2012 Prize for Industrial Development presented by
Japan Fine Ceramics Association
*1
First use: Based on Kyocera’s research of this type of joint
using biocompatible polymer (as of June 12, 2018) *2 PMPC:
Poly(2-methacryloyloxyethyl phosphorylcholine [MPC]), an
implantable biocompatible polymer *3 Biomimetic: The science of
solving complex human challenges using models from nature *4
Nano-surface treatment: Surface processing at approximately 100
nanometer scale (one 10,000th of a millimeter). *5
Reference Source: [Moro T, Takatori
Y, Kyomoto M, Ishihara K, Hashimoto M, Ito H, Tanaka T, Oshima H,
Tanaka S, Kawaguchi H: Long-term hip simulator testing of the
artificial hip joint bearing surface grafted with biocompatible
phospholipid polymer. J Orthop Res32(3): 369-376, 2014]
* Aquala is trademark of Kyocera
Corporation
About KYOCERAKyocera Corporation (NYSE:KYO; TOKYO:6971;
http://global.kyocera.com/), the parent and global headquarters of
the Kyocera Group, was founded in 1959 as a producer of fine
ceramics (also known as “advanced ceramics”). By combining these
engineered materials with metals and integrating them with other
technologies, Kyocera has become a leading supplier of
semiconductor packages, industrial and automotive components,
electronic devices, solar power generating systems, printers,
copiers, and mobile phones. During the year ended March 31, 2018,
the company’s consolidated net sales totaled 1.58 trillion yen
(approx. USD14.9 billion). Kyocera appears on the “Top 100 Global
Innovators” list by Clarivate Analytics and is ranked #612 on
Forbes magazine’s 2018 “Global 2000” listing of the world’s largest
publicly traded companies.
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KYOCERA Corporation (Japan)Kenichi Hara,
+81-(0)75-604-3416Corporate
Communicationswebmaster.pressgl@kyocera.jpFax:
+81-(0)75-604-3516
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