Aptose Biosciences Inc (APS)

It's all over but the shouting. A cash merger of $2.41 per share is going to take the company private. Some of you had a decade invested here. When you are out looking for the next biotech opportunity, keep an eye out to see if the old Aptose team is involved....

Okay...I'll throw in one final entry. Just like the development of a single treatment for TUS, Aptose is now playing the dosage game with , what I call, the "Trio Trial". A new Phase I/II trial at 160 mg is going to enroll......instead of pushing the highest lower dose through to Phase III and an NDA. Once a first treatment gets approved, that success can propel a company to gather a regulatory audience for testing subsequent doses. Anyone want to venture a guess as to when a final review might take place? 2035 maybe?

Talk about the next reverse split! The stock is at .95, and this morning's headlines referred to a missing interest payment to a pharma creditor. UGH.

Well....I have had six entries in the past 3 1/2 months. I guess I'm about through here. My 3-5-25 entry was somewhat tongue-in-cheek.......but then the company announces yet ANOTHER reverse split at the abbreviated annual meeting. No date or amount given....but it could be from a 1 for 2 to a 1 for 20. The company's accountants bailed. One might wonder why. Anywhoooo.......it's time to move on. I'll keep an eye on it from time to time, but I am not going to bother you all with my concerns over this outfit.

$1.68 The short/intermediate term issue is that there doesn't seem to be any catalyst to drive this stock forward until the "partners" actually settle on a dosage, expand the Phase 1/2 trial to cover enough people to make it meaningful, and somehow decide that enough is enough and apply for Phase III. Does anyone want to guess on a timeframe?

An April 17 close of $1.97 and this morning at $2.20.

APTO changed to APTOF. Delisted from the Nasdaq to the OTCL

https://otce.finra.org/otce/dailyList?viewType=Additions

Wow.......$2.67. This thing might be ready for a "buy" after the next reverse split. There won't be much stock left.

So....in three days post split the stock has dropped from $3.64 to $3.09.

APTO POST SPLIT POPPA

1 for 30 R/S on Feb 26th

R/S on Feb 26th

Today's press release refers to Round 3 of dosage experiments.......this time with the combo.

For the time being it's holding on .32 ??????

APTO.....................................https://stockcharts.com/h-sc/ui?s=APTO&p=W&b=5&g=0&id=p86431144783

REVERSE SPLIT APPROVED ( JANUARY 27, 2025 )... REVERSE SPLIT DATE ANNOUNCEMENT IMMINENT

You'll notice that recent announcements have NOT propelled the stock upward. Reverse splits are not dilutive, but new stock offerings, to the public or as a private placement, are dilutive because they do affect the percentage of ownership for each shareholder. The product results news has been positive so far, but it will take administering the product to many more patients just to get out of Phase 1/2 and into Phase 3. I assume these stock offerings will be made post-split.

APTO: I have to take a SONG break!! (My new Los Angeles County, California, THEME SONG!! Which should be REQUIRED LISTENING for all the STUPID County Officials who reside therein. As auditory PUNISHMENT, of sorts, for NEVER doing what has had to be accomplished there for 70+-YEARS!!! Namely, systematically REMOVING FOREVER every single TREE, BUSH, SHRUB, & BLADE OF GRASS therein!!! For at least 1.5-MILES around all housing developments throughout that stupid County!!! And then COVER that entire area permanently with GRAVEL, STONE, CONCRETE, STAINLESS STEEL, etc., FOREVER!!!)

APTO: Looks like this has a Wall Street Police ROADBLOCK at $0.25 cents!!! (DAMN-IT!!!)

APTO: And I hope ya take us BOTH to $2.00, by the end of this SLOOOOOOOOW day, Bro!!!!

In at .24 

APTO: Holy STOCK EXPLOSION, Batman!!! What-the-FLUCK was that???!!! (Fret not, Robin!!! Just continue our glorious laughin'-&-runnin' all the way to our BANK!!!)

APTO: I grabbed some. (But, any "DD" behind this firm is [supposedly] not very encouraging; hope I'm WRONG!!)

APTO very nice news

Three patients with unmutated (wildtype) FLT3 (FLT3-WT) completed Cycle 1 of treatment with no dose-limiting toxicities (DLTs) and no dose adjustments.

Two FLT3-WT patients achieved complete remissions (CR and CRh) by the end of Cycle 1.

Notably, a patient with biallelic TP53 mutations and a complex karyotype obtained CR.

The third FLT3-WT patient experienced significant reductions in bone marrow leukemic blasts during Cycle 1 and remains on therapy in Cycle 2.

Ticker: NXU. 600 Billion Market Merge just Approved! Moon 

I SEE A RS HAS BEEN VOTED IN 1-10 TO 1-30

APTO 6 WEEKS TO DELIST...SO RS NEWS SHOULD COME SOON...

APTO: Nice news!!!
https://finance.yahoo.com/news/aptose-frontline-triple-drug-therapy-120000446.html

APTO.........................https://stockcharts.com/h-sc/ui?s=APTO&p=W&b=5&g=0&id=p86431144783

Well......have you all seen the latest correspondence from the company? Yup........another reverse split is on the way. I was ornery and voted against it.

APTO..........https://stockcharts.com/h-sc/ui?s=APTO&p=W&b=5&g=0&id=p86431144783

Looks like a I’m going to take a loss on this one

Okay, everyone. The company basically has three months to get its act together and retain its NASDAQ listing. No revenues are projected for 2025. These new collaborations are going to take time to develop. The last time the company had to scramble to retain its NASDAQ listing, what did it have to do? A reverse split. The company hasn't even been able to find its own way to Phase !!! testing with Tus....let alone Lux. So....what is it going to have to do again....unless its gets some blockbuster FDA news by March 31? Another reverse split. This day has been coming since the last reverse split was done.

apto............................https://stockcharts.com/h-sc/ui?s=apto&p=W&b=5&g=0&id=p86431144783

https://ih.advfn.com/stock-market/NASDAQ/aptose-biosciences-APTO/stock-news/95133778/aptose-announces-positive-decision-by-nasdaq-heari

lol


sorry

lol - nice Post

Nice making another round 

"EOIC", like at this link???
https://www.google.com/search?q=What+does+%22EOIC%22+mean+in+street+slang%3F&sca_esv=790e11adc1912a92&source=hp&ei=YJ1kZ8HrO-PbkPIPxKCYyAY&iflsig=AL9hbdgAAAAAZ2SrcT_uYmDaX2twpgyJ6L581HqdxC_A&ved=0ahUKEwjBm6ST8LSKAxXjLUQIHUQQBmkQ4dUDCBU&oq=What+does+%22EOIC%22+mean+in+street+slang%3F&gs_lp=Egdnd3Mtd2l6IiZXaGF0IGRvZXMgIkVPSUMiIG1lYW4gaW4gc3RyZWV0IHNsYW5nPzIHECEYoAEYCjIHECEYoAEYCjIHECEYoAEYCjIHECEYoAEYCkjywwJQAFi7dnAEeACQAQCYAeUBoAG1HKoBBzE2LjEzLjO4AQzIAQD4AQGYAiSgAssgwgIKEAAYgAQYRhj5AcICCBAAGIAEGLEDwgIFEAAYgATCAg4QABiABBixAxiDARiKBcICBxAAGIAEGArCAgwQABiABBgKGEYY-QHCAgcQABiABBgNwgIGEAAYFhgewgIIEAAYCBgNGB7CAgsQABiABBiGAxiKBcICCBAAGIAEGKIEwgIFECEYqwKYAwCSBwcxMy4yMC4zoAeN-wE&sclient=gws-wiz
////////////////////////////////////////////////////////////////////////////////////////////////////////////////////////////////////////////////////////////////////////
Or, did you mean to type, "EPIC"????

APTO: No brainer here, K-N-R, in my STUPID opinion!!! (Heck, I just scalped a cheap Lotto Ticket [$1K] on @NVDI in the Post-M several minutes ago for $300 profit; 'small potatoes' for sure, but given this latest rage of JUST-RESCUED-FOR-CONTINUED-NASDAQ-LISTING late PR's, who can resist this stuff???!!!)

Sounds eoic

holy ahi_ ....coming Dollarland tomorrow ??

APTO: Flip-&-scalp these NASDAQ orphans all day long!!!

APTO: Back on the NASDAQ, a little more securely!!! (Another 10-bagger???)

$APTO Aptose Announces Positive Decision by Nasdaq Hearings Panel

Pop on this— AlertsAndNews (@AlertsAndNews) December 19, 2024

Well....a Phase III push for Tus is on the back burner again. First the company decides to go it alone but can't decide on a dosage. Then it wants to partner with a 2nd party.......and now a 3rd. Comments, anyone?

In some .38s looks bottomy typical hedgie beat down bio

APTO new 52=week low

APTO new 52 week low

Another reverse split seems inevitable. The cash infusion, hopefully, will hasten the company to eventually reach a Phase III status on Tusp sometime during my lifetime.