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UNITED STATES
SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 10-Q
☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934
For the quarterly period ended June 30, 2024
OR
☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934
Commission File Number: 001-35092
EXACT SCIENCES CORPORATION
(Exact name of registrant as specified in its charter)
Delaware02-0478229
(State or other jurisdiction of
incorporation or organization)
(I.R.S. Employer
Identification Number)
5505 Endeavor Lane, Madison WI
53719
(Address of principal executive offices)(Zip Code)
(608) 535-8815 (Registrant’s telephone number, including area code)
Securities registered pursuant to Section 12(b) of the Act:
Title of each classTrading Symbol(s)Name of each exchange on which registered
Common Stock, $0.01 par value per shareEXASThe Nasdaq Stock Market LLC
Indicate by check mark whether the registrant: (1) has filed all reports required to be filed by Section 13 or 15(d) of the Securities Exchange Act of 1934 during the preceding 12 months (or for such shorter period that the registrant was required to file such reports), and (2) has been subject to such filing requirements for the past 90 days. Yes ☒ No ☐
Indicate by check mark whether the registrant has submitted electronically, if any, every Interactive Data File required to be submitted pursuant to Rule 405 of Regulation S-T (§232.405 of this chapter) during the preceding 12 months (or for such shorter period that the registrant was required to submit such files). Yes ☒ No ☐
Indicate by check mark whether the registrant is a large accelerated filer, an accelerated filer, a non-accelerated filer, a smaller reporting company, or an emerging growth company. See the definitions of “large accelerated filer,” “accelerated filer,” “smaller reporting company,” and “emerging growth company” in Rule 12b-2 of the Exchange Act.
Large accelerated filer☒Accelerated filer ☐
Non-accelerated filer☐Smaller reporting company ☐
Emerging growth company ☐
If an emerging growth company, indicate by check mark if the registrant has elected not to use the extended transition period for complying with any new or revised financial accounting standards provided pursuant to Section 13(a) of the Exchange Act. ☐
Indicate by check mark whether the registrant is a shell company (as defined in Rule 12b-2 of the Exchange Act). Yes ☐ No ☒
As of July 30, 2024, the registrant had 184,769,862 shares of common stock outstanding.


EXACT SCIENCES CORPORATION
INDEX
Page
Number

2
EXACT SCIENCES CORPORATION
Condensed Consolidated Balance Sheets
(Amounts in thousands, except share data - unaudited)
Part I — Financial Information
June 30, 2024December 31, 2023
ASSETS
Current assets:
Cash and cash equivalents$530,180 $605,378 
Marketable securities416,602 172,266 
Accounts receivable, net263,865 203,623 
Inventory127,373 127,475 
Prepaid expenses and other current assets114,467 85,627 
Total current assets1,452,487 1,194,369 
Long-term Assets:
Property, plant and equipment, net703,083 698,354 
Operating lease right-of-use assets139,807 143,708 
Goodwill2,366,972 2,367,120 
Intangible assets, net1,843,478 1,890,396 
Other long-term assets, net167,468 177,387 
Total assets$6,673,295 $6,471,334 
LIABILITIES AND STOCKHOLDERS’ EQUITY
Current liabilities:
Accounts payable$52,980 $78,816 
Accrued liabilities302,540 341,683 
Operating lease liabilities, current portion27,096 29,379 
Convertible notes, net, current portion
248,923 — 
Debt, current portion— 50,000 
Other current liabilities37,103 14,823 
Total current liabilities668,642 514,701 
Long-term liabilities:
Convertible notes, net, less current portion
2,317,948 2,314,276 
Other long-term liabilities326,678 335,982 
Operating lease liabilities, less current portion167,665 161,070 
Total liabilities3,480,933 3,326,029 
Commitments and contingencies (Note 13)
Stockholders’ equity:
Preferred stock, $0.01 par value Authorized—5,000,000; shares issued and outstanding—no shares at June 30, 2024 and December 31, 2023
— — 
Common stock, $0.01 par value Authorized—400,000,000; shares issued and outstanding—184,668,188 and 181,364,180 shares at June 30, 2024 and December 31, 2023
1,848 1,815 
Additional paid-in capital6,786,668 6,611,237 
Accumulated other comprehensive income (loss)
(943)1,428 
Accumulated deficit(3,595,211)(3,469,175)
Total stockholders’ equity3,192,362 3,145,305 
Total liabilities and stockholders’ equity$6,673,295 $6,471,334 
The accompanying notes are an integral part of these condensed consolidated financial statements.
3
EXACT SCIENCES CORPORATION
Condensed Consolidated Statements of Operations
(Amounts in thousands, except per share data - unaudited)
Three Months Ended June 30,Six Months Ended June 30,
2024202320242023
Revenue$699,264 $622,093 $1,336,788 $1,224,543 
Operating expenses
Cost of sales (exclusive of amortization of acquired intangible assets)189,848 156,991 359,949 313,857 
Research and development120,884 104,095 231,492 199,514 
Sales and marketing185,270 176,490 377,635 363,454 
General and administrative201,856 237,965 444,973 455,260 
Amortization of acquired intangible assets23,311 22,929 46,622 45,857 
Impairment of long-lived assets8,152 552 12,598 621 
Total operating expenses729,321 699,022 1,473,269 1,378,563 
Other operating income3,800 — 3,532 — 
Loss from operations(26,257)(76,929)(132,949)(154,020)
Other income (expense)
Investment income, net
11,801 4,828 18,014 5,318 
Interest income (expense), net
111 (7,818)(7,832)(3,711)
Total other income (expense)11,912 (2,990)10,182 1,607 
Net loss before tax(14,345)(79,919)(122,767)(152,413)
Income tax expense
(1,463)(1,107)(3,269)(2,764)
Net loss$(15,808)$(81,026)$(126,036)$(155,177)
Net loss per share—basic and diluted$(0.09)$(0.45)$(0.69)$(0.87)
Weighted average common shares outstanding—basic and diluted184,313 180,204 183,332 179,393 
The accompanying notes are an integral part of these condensed consolidated financial statements.
4
EXACT SCIENCES CORPORATION
Condensed Consolidated Statements of Comprehensive Loss
(Amounts in thousands - unaudited)
Three Months Ended June 30,Six Months Ended June 30,
2024202320242023
Net loss
$(15,808)$(81,026)$(126,036)$(155,177)
Other comprehensive loss, net of tax:
Unrealized gain (loss) on available-for-sale investments(138)937 (925)3,904 
Foreign currency adjustment
(306)59 (1,446)609 
Comprehensive loss$(16,252)$(80,030)$(128,407)$(150,664)
The accompanying notes are an integral part of these condensed consolidated financial statements.
5
EXACT SCIENCES CORPORATION
Condensed Consolidated Statements of Stockholders’ Equity
(Amounts in thousands, except share data - unaudited)
Common StockAdditional Paid-In Capital
Accumulated Other Comprehensive Income (Loss)
Accumulated DeficitTotal Stockholders’ Equity
Number of Shares
$0.01
Par Value
Balance, January 1, 2024181,364,180 $1,815 $6,611,237 $1,428 $(3,469,175)$3,145,305 
Exercise of common stock options, net of shares withheld for taxes71,537 1 (1,409)— — (1,408)
Issuance of common stock upon settlement of restricted stock awards, net of shares withheld for taxes1,792,087 17 (61)— — (44)
Issuance of common stock to fund the Company’s 2023 401(k) match
617,384 6 40,544 — — 40,550 
Stock-based compensation expense— — 60,370 — — 60,370 
Net loss— — — — (110,228)(110,228)
Other comprehensive loss
— — — (1,927)— (1,927)
Balance, March 31, 2024183,845,188 $1,839 $6,710,681 $(499)$(3,579,403)$3,132,618 
Exercise of common stock options, net of shares withheld for taxes8,184 1 42 — — 43 
Issuance of common stock upon settlement of restricted stock awards, net of shares withheld for taxes210,590 2 (6)— — (4)
Stock-based compensation expense— — 56,555 — — 56,555 
Purchase of employee stock purchase plan shares604,226 6 19,396 — — 19,402 
Net loss— — — — (15,808)(15,808)
Other comprehensive loss
— — — (444)— (444)
Balance, June 30, 2024184,668,188 $1,848 $6,786,668 $(943)$(3,595,211)$3,192,362 

6
EXACT SCIENCES CORPORATION
Condensed Consolidated Statements of Stockholders’ Equity
(Amounts in thousands, except share data - unaudited)
Common StockAdditional Paid-In Capital
Accumulated Other Comprehensive Income (Loss)
Accumulated DeficitTotal Stockholders’ Equity
Number of Shares
$0.01
Par Value
Balance, January 1, 2023177,925,631 $1,780 $6,311,644 $(5,236)$(3,265,026)$3,043,162 
Exercise of common stock options, net of shares withheld for taxes88,228 1 963 — — 964 
Issuance of common stock upon settlement of restricted stock awards, net of shares withheld for taxes1,299,071 13 (13)— — — 
Issuance of common stock to fund the Company’s 2022 401(k) match517,215 5 35,072 — — 35,077 
Stock-based compensation expense— — 49,139 — — 49,139 
Net loss— — — — (74,151)(74,151)
Other comprehensive income
— — — 3,517 — 3,517 
Balance, March 31, 2023179,830,145 $1,799 $6,396,805 $(1,719)$(3,339,177)$3,057,708 
Exercise of common stock options36,728 1 851 — — 852 
Issuance of common stock upon settlement of restricted stock awards, net of shares withheld for taxes134,002 1 (1)— — — 
Issuance of common stock to fund the Company’s 2022 401(k) match335 — 23 — — 23 
Stock-based compensation expense— — 61,725 — — 61,725 
Purchase of employee stock purchase plan shares544,453 5 16,339 — — 16,344 
Net loss— — — — (81,026)(81,026)
Other comprehensive income— — — 996 — 996 
Balance, June 30, 2023180,545,663 $1,806 $6,475,742 $(723)$(3,420,203)$3,056,622 
The accompanying notes are an integral part of these condensed consolidated financial statements.
7
EXACT SCIENCES CORPORATION
Condensed Consolidated Statements of Cash Flows
(Amounts in thousands - unaudited)
Six Months Ended June 30,
20242023
Cash flows from operating activities:
Net loss$(126,036)$(155,177)
Adjustments to reconcile net loss to net cash provided by (used in) operating activities:
Depreciation60,319 54,325 
Loss on non-marketable and marketable equity investments
1,115 4,741 
Deferred tax expense
2,225 672 
Stock-based compensation116,925 110,864 
Gain on settlements of convertible notes, net(10,254)(10,324)
Amortization of acquired intangible assets46,622 45,857 
Impairment of long-lived assets12,598 621 
Remeasurement of contingent consideration from sale of asset
(3,532)— 
Remeasurement of contingent consideration liabilities(7,636)(4,687)
Non-cash lease expense14,042 13,777 
Other(2,667)3,965 
Changes in assets and liabilities:
Accounts receivable, net(60,901)(20,492)
Inventory, net96 (12,531)
Operating lease liabilities(12,957)(12,766)
Accounts payable and accrued liabilities(17,865)48,754 
Other assets2,719 (9,624)
Other liabilities9,941 4,234 
Net cash provided by operating activities
24,754 62,209 
Cash flows from investing activities:
Purchases of marketable securities(324,372)(50,656)
Maturities and sales of marketable securities80,335 270,825 
Purchases of property, plant and equipment(73,515)(64,081)
Purchases of non-marketable investments
(810)(6,173)
Other investing activities(205)(500)
Net cash provided by (used in) investing activities
(318,567)149,415 
Cash flows from financing activities:
Proceeds from exercise of common stock options, net of cash paid for taxes(1,365)1,816 
Proceeds in connection with the Company’s employee stock purchase plan19,402 16,344 
Proceeds from issuance of convertible notes266,750 137,976 
Payments on accounts receivable securitization facility(50,000)— 
Other financing activities(13,186)(6,499)
Net cash provided by financing activities
221,601 149,637 
Effects of exchange rate changes on cash and cash equivalents(1,446)609 
Net increase (decrease) in cash, cash equivalents and restricted cash(73,658)361,870 
Cash, cash equivalents and restricted cash, beginning of period609,675 242,790 
Cash, cash equivalents and restricted cash, end of period$536,017 $604,660 


8
EXACT SCIENCES CORPORATION
Condensed Consolidated Statements of Cash Flows
(Amounts in thousands - unaudited)
Six Months Ended June 30,
20242023
Supplemental disclosure of non-cash investing and financing activities
Property, plant and equipment acquired but not paid$12,442 $7,850 
Supplemental disclosure of cash flow information:
Interest paid$11,971 $7,385 
Reconciliation of cash, cash equivalents and restricted cash:
Cash and cash equivalents$530,180 $604,363 
Restricted cash — included in other long-term assets, net
5,837 297 
Total cash, cash equivalents and restricted cash$536,017 $604,660 
The accompanying notes are an integral part of these condensed consolidated financial statements.
9
EXACT SCIENCES CORPORATION
Notes to Condensed Consolidated Financial Statements
(Unaudited)

(1) SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES
Business
Exact Sciences Corporation (together with its subsidiaries, “Exact,” or the “Company”) was incorporated in February 1995. A leading provider of cancer screening and diagnostic tests, Exact Sciences gives patients and health care professionals the clarity needed to take life-changing action earlier. Building on the success of the Cologuard® and Oncotype DX® tests, Exact Sciences is investing in its pipeline to develop innovative solutions for use before, during, and after a cancer diagnosis.
Basis of Presentation and Principles of Consolidation
The accompanying condensed consolidated financial statements, which include the accounts of the Company and those of its wholly owned subsidiaries and variable interest entities, are unaudited and have been prepared on a basis substantially consistent with the Company’s audited financial statements and notes as of and for the year ended December 31, 2023 included in the Company’s Annual Report on Form 10-K (the “2023 Form 10-K”). All intercompany transactions and balances have been eliminated upon consolidation. These condensed consolidated financial statements are prepared in conformity with accounting principles generally accepted (“GAAP”) in the United States of America (“U.S.”) and follow the requirements of the Securities and Exchange Commission (“SEC”) for interim reporting. In the opinion of management, the accompanying unaudited condensed consolidated financial statements contain all adjustments (consisting only of adjustments of a normal and recurring nature) considered necessary for a fair statement of its financial position, operating results and cash flows for the periods presented. The condensed consolidated balance sheet at December 31, 2023 has been derived from audited financial statements, but does not contain all of the footnote disclosures from the 2023 Form 10-K. The results of the Company’s operations for any interim period are not necessarily indicative of the results of the Company’s operations for any other interim period or for a full fiscal year. The statements should be read in conjunction with the audited financial statements and related notes included in the 2023 Form 10-K.
Use of Estimates
The preparation of the condensed consolidated financial statements in conformity with GAAP requires management to make estimates and assumptions that affect the reported amounts of assets and liabilities and disclosure of contingent assets and liabilities at the date of the financial statements and the reported amounts of revenues and expenses during the reporting period. Critical accounting policies are those that affect the Company’s financial statements materially and involve difficult, subjective or complex judgments by management, and actual results could differ from those estimates. These estimates include revenue recognition, valuation of intangible assets and goodwill, contingent consideration, and accounting for income taxes. The Company’s critical accounting policies and estimates are explained further in the notes to the condensed consolidated financial statements in this Quarterly Report on Form 10-Q and the 2023 Form 10-K.
Significant Accounting Policies
During the six months ended June 30, 2024, there were no changes to the Company’s significant accounting policies as described in the Company’s 2023 Form 10-K, except as described in the Recently Adopted Accounting Pronouncements sections below.
Recent Accounting Pronouncements
Recently Adopted Accounting Pronouncements
In March 2024, the Financial Accounting Standards Board (“FASB”) issued Accounting Standards Update (“ASU”) No. 2024-02: Codification Improvement – Amendments to Remove References to the Concepts Statements. This update amends the Accounting Standards Codification (“ASC”) to remove references to various FASB Concepts Statements. The Company early adopted and prospectively applied the amendments in this update during the first quarter of fiscal year 2024. There was no significant impact to the Company’s condensed consolidated financial statements.
10
EXACT SCIENCES CORPORATION
Notes to Condensed Consolidated Financial Statements
(Unaudited)
Recently Issued Accounting Pronouncements Not Yet Adopted
In October 2023, the FASB issued ASU No. 2023-06, Disclosure Improvements: Codification Amendments in Response to the SEC’s Disclosure Update and Simplification Initiative. This update modifies the disclosure or presentation requirements of a variety of topics in the ASC to conform with certain SEC amendments in Release No. 33-10532, Disclosure Update and Simplification. The amendments in this update should be applied prospectively, and the effective date for each amendment will be the date on which the SEC’s removal of that related disclosure from Regulation S-X or S-K becomes effective. However, if the SEC has not removed the related disclosure from its regulations by June 30, 2027, the amendments will be removed from the Codification and not become effective. Early adoption is prohibited. The Company is currently evaluating the potential impact of this guidance on its condensed consolidated financial statements.
In November 2023, the FASB issued ASU No. 2023-07, Segment Reporting (Topic 280): Improvements to Reportable Segment Disclosures. This update improves reportable segment disclosure requirements, primarily through enhanced disclosures of significant segment expenses. The amendments in this update should be applied retrospectively to all prior periods presented in the consolidated financial statements and are effective for fiscal years beginning after December 31, 2023 and interim periods within fiscal years beginning after December 31, 2024. Early adoption is permitted. The Company is currently evaluating the potential impact of this guidance on its condensed consolidated financial statements.
In December 2023, the FASB issued ASU No. 2023-09, Income Taxes (Topic 740): Improvement to Income Tax Disclosures. This update improves income tax disclosure requirements, primarily through enhanced transparency and decision usefulness of disclosures. The amendments in this update should be applied prospectively with the option to apply retrospectively and are effective for fiscal years beginning after December 15, 2024. Early adoption is permitted. The Company is currently evaluating the potential impact of this guidance on its condensed consolidated financial statements.
Net Loss Per Share
Basic net loss per common share (“EPS”) was determined by dividing net loss applicable to common stockholders by the weighted average common shares outstanding during the period. Basic and diluted net loss per share is the same because all outstanding common stock equivalents have been excluded, as they are anti-dilutive as a result of the Company’s losses.
The following potentially issuable common shares were not included in the computation of diluted net loss per share because they would have an anti-dilutive effect due to net losses for each period:
June 30,
(In thousands)20242023
Shares issuable upon conversion of convertible notes26,526 23,231 
Shares issuable upon the release of restricted stock awards7,781 6,590 
Shares issuable upon the release of performance share units2,104 1,569 
Shares issuable upon exercise of stock options1,128 1,366 
37,539 32,756 

(2) REVENUE
The Company’s revenue is primarily generated by its laboratory testing services utilizing its Cologuard and Oncotype® tests. The services are considered completed upon release of a patient’s test result to the ordering healthcare provider.
11
EXACT SCIENCES CORPORATION
Notes to Condensed Consolidated Financial Statements
(Unaudited)
The following table presents the Company’s revenues disaggregated by revenue source:
Three Months Ended June 30,Six Months Ended June 30,
(In thousands)2024202320242023
Screening
Medicare Parts B & C$195,337 $176,016 $369,127 $347,746 
Commercial283,729 245,748 537,872 478,781 
Other52,540 41,023 99,405 79,455 
Total Screening531,606 462,787 1,006,404 905,982 
Precision Oncology
Medicare Parts B & C$47,467 $47,588 $95,517 $94,969 
Commercial49,187 46,212 95,887 91,144 
International46,722 35,586 91,255 72,854 
Other24,282 27,788 47,725 53,639 
Total Precision Oncology167,658 157,174 330,384 312,606 
COVID-19 Testing$— $2,132 $— $5,955 
Total$699,264 $622,093 $1,336,788 $1,224,543 
Screening revenue primarily includes laboratory service revenue from Cologuard and Prevention Genetics, LLC (“PreventionGenetics”) tests while Precision Oncology revenue primarily includes laboratory service revenue from global Oncotype DX and therapy selection tests.
At each reporting period end, the Company conducts an analysis of the estimates used to calculate the transaction price to determine whether any new information available impacts those estimates made in prior reporting periods. Adjustments to revenue recognized during the period relating to prior period estimates were less than 1% of revenue recorded in the Company’s condensed consolidated statement of operations for the three and six months ended June 30, 2024. Adjustments to revenue recognized during the period relating to prior period estimates were less than 2% of revenue recorded in the Company’s condensed consolidated statement of operations for the three and six months ended June 30, 2023.
The Company’s deferred revenue, which is reported in other current liabilities in the Company’s condensed consolidated balance sheets, was not significant as of June 30, 2024 and December 31, 2023.
Revenue recognized for the three and six months ended June 30, 2024 and 2023 that was included in the deferred revenue balance at the beginning of the period was not significant.

12
EXACT SCIENCES CORPORATION
Notes to Condensed Consolidated Financial Statements
(Unaudited)
(3) MARKETABLE SECURITIES
The following table sets forth the Company’s cash, cash equivalents, and marketable securities at June 30, 2024 and December 31, 2023:
(In thousands)June 30, 2024December 31, 2023
Cash and cash equivalents
Cash and money market$519,836 $530,100 
Cash equivalents10,344 75,278 
Total cash and cash equivalents530,180 605,378 
Marketable securities
Available-for-sale debt securities$414,271 $168,425 
Equity securities2,331 3,841 
Total marketable securities416,602 172,266 
Total cash, cash equivalents and marketable securities$946,782 $777,644 
Available-for-sale debt securities, including the classification within the condensed consolidated balance sheet at June 30, 2024, consisted of the following:
(In thousands)Amortized CostGains in Accumulated Other Comprehensive Income (Loss) (1)Losses in Accumulated Other Comprehensive Income (Loss) (1)Estimated Fair Value
Cash equivalents
U.S. government agency securities$10,344 $— $— $10,344 
Total cash equivalents10,344 — — 10,344 
Marketable securities
Corporate bonds$203,728 $160 $(600)$203,288 
U.S. government agency securities118,753 3 (130)118,626 
Asset backed securities87,718 21 (325)87,414 
Commercial paper4,943 — — 4,943 
Total marketable securities415,142 184 (1,055)414,271 
Total available-for-sale securities$425,486 $184 $(1,055)$424,615 
______________
(1)There was no tax impact from the gains and losses in accumulated other comprehensive income (loss) (“AOCI”).
13
EXACT SCIENCES CORPORATION
Notes to Condensed Consolidated Financial Statements
(Unaudited)
Available-for-sale debt securities, including the classification within the condensed consolidated balance sheet at December 31, 2023, consisted of the following:
(In thousands)Amortized CostGains in Accumulated Other Comprehensive Income (Loss) (1) Losses in Accumulated Other Comprehensive Income (Loss) (1)Estimated Fair Value
Cash equivalents
Commercial paper$72,243 $— $— $72,243 
U.S. government agency securities3,035 — — 3,035 
Total cash equivalents75,278 — — 75,278 
Marketable securities
U.S. government agency securities$56,594 $166 $(44)$56,716 
Corporate bonds55,712 175 (59)55,828 
Asset backed securities35,081 65 (249)34,897 
Commercial paper
20,984 — — 20,984 
Total marketable securities168,371 406 (352)168,425 
Total available-for-sale securities$243,649 $406 $(352)$243,703 
______________
(1)There was no tax impact from the gains and losses in AOCI.
The following table summarizes contractual underlying maturities of the Company’s available-for-sale debt securities at June 30, 2024:
Due one year or lessDue after one year through five years
(In thousands)CostFair ValueCostFair Value
Cash equivalents
U.S. government agency securities$10,344 $10,344 $— $— 
Total cash equivalents10,344 10,344 — — 
Marketable securities
U.S. government agency securities$108,950 $108,844 $9,803 $9,782 
Corporate bonds46,393 46,288 157,335 157,000 
Asset backed securities5,901 5,892 81,817 81,522 
Commercial paper
4,943 4,943 — — 
Total marketable securities166,187 165,967 248,955 248,304 
Total available-for-sale securities$176,531 $176,311 $248,955 $248,304 
14
EXACT SCIENCES CORPORATION
Notes to Condensed Consolidated Financial Statements
(Unaudited)
The following table summarizes the gross unrealized losses and fair values of available-for-sale debt securities in an unrealized loss position as of June 30, 2024 aggregated by investment category and length of time those individual securities have been in a continuous unrealized loss position:
Less than one yearOne year or greaterTotal
(In thousands)Fair ValueGross Unrealized LossFair ValueGross Unrealized LossFair ValueGross Unrealized Loss
Marketable securities
Corporate bonds$129,953 $(578)$4,720 $(22)$134,673 $(600)
U.S. government agency securities108,835 (108)3,913 (22)112,748 (130)
Asset backed securities53,722 (211)6,532 (114)60,254 (325)
Total available-for-sale securities$292,510 $(897)$15,165 $(158)$307,675 $(1,055)
The Company evaluates investments that are in an unrealized loss position for impairment as a result of credit loss. It was determined that no credit losses exist as of June 30, 2024 and December 31, 2023 because the change in market value for those securities in an unrealized loss position resulted from fluctuating interest rates rather than a deterioration of the credit worthiness of the issuers.
The gains and losses recorded on available-for-sale debt securities and equity securities are included in investment income, net in the Company’s condensed consolidated statements of operations. The gains and losses recorded were not material for the three and six months ended June 30, 2024 and 2023.

(4) INVENTORY
Inventory consisted of the following:
(In thousands)June 30, 2024December 31, 2023
Raw materials$52,363 $58,593 
Semi-finished and finished goods75,010 68,882 
Total inventory$127,373 $127,475 
15
EXACT SCIENCES CORPORATION
Notes to Condensed Consolidated Financial Statements
(Unaudited)
(5) PROPERTY, PLANT AND EQUIPMENT
The carrying value and estimated useful lives of property, plant and equipment are as follows:
(In thousands)Estimated Useful LifeJune 30, 2024December 31, 2023
Property, plant and equipment
Landn/a$4,716 $4,716 
Leasehold and building improvements(1)228,513 214,562 
Land improvements15 years6,747 6,729 
Buildings
30 - 40 years
290,777 290,777 
Computer equipment and computer software3 years198,247 168,131 
Machinery and equipment
3 - 10 years
308,052 290,294 
Furniture and fixtures
3 - 10 years
36,278 35,756 
Assets under constructionn/a100,653 104,592 
Property, plant and equipment, at cost1,173,983 1,115,557 
Accumulated depreciation(470,900)(417,203)
Property, plant and equipment, net$703,083 $698,354 
______________
(1)Lesser of remaining lease term, building life, or estimated useful life.
Depreciation expense for the three months ended June 30, 2024 and 2023 was $29.7 million and $27.5 million, respectively. Depreciation expense for the six months ended June 30, 2024 and 2023 was $60.3 million and $54.3 million, respectively.
At June 30, 2024, the Company had $100.7 million of assets under construction, which consisted of $62.6 million in machinery and equipment, $24.8 million in capitalized costs related to software projects, $8.1 million in leasehold and building improvements, $5.1 million related to buildings, and minimal furniture and fixtures. Depreciation will begin on these assets once they are placed into service upon completion.

(6) INTANGIBLE ASSETS AND GOODWILL
Intangible Assets
The following table summarizes the net-book-value and estimated remaining life of the Company’s intangible assets as of June 30, 2024:
(In thousands)Weighted Average Remaining Life (Years)CostAccumulated Amortization
Net Balance at June 30, 2024
Finite-lived intangible assets
Trade name11.2$104,000 $(31,528)$72,472 
Customer relationships6.54,000 (1,111)2,889 
Patents and licenses5.911,542 (10,324)1,218 
Acquired developed technology (1)6.8887,352 (370,453)516,899 
Total finite-lived intangible assets1,006,894 (413,416)593,478 
In-process research and developmentn/a1,250,000 — 1,250,000 
Total intangible assets$2,256,894 $(413,416)$1,843,478 
16
EXACT SCIENCES CORPORATION
Notes to Condensed Consolidated Financial Statements
(Unaudited)
The following table summarizes the net-book-value and estimated remaining life of the Company’s intangible assets as of December 31, 2023:
(In thousands)Weighted Average Remaining Life (Years)CostAccumulated Amortization
Net balance at December 31, 2023
Finite-lived intangible assets
Trade name11.6$104,000 $(27,903)$76,097 
Customer relationships7.04,000 (889)3,111 
Patents and licenses4.511,542 (9,600)1,942 
Acquired developed technology (1)7.3887,789 (328,543)559,246 
Total finite-lived intangible assets1,007,331 (366,935)640,396 
In-process research and developmentn/a1,250,000 — 1,250,000 
Total intangible assets$2,257,331 $(366,935)$1,890,396 
______________
(1)The gross carrying amount includes an insignificant foreign currency translation adjustment related to the intangible asset acquired as a result of the acquisition of OmicEra Diagnostics GmbH (“OmicEra”).
As of June 30, 2024 the estimated future amortization expense associated with the Company’s finite-lived intangible assets for each of the five succeeding fiscal years is as follows:
(In thousands)
2024 (remaining six months)$46,288 
202591,860 
202690,800 
202790,800 
202890,800 
Thereafter182,930 
$593,478 
The Company’s acquired intangible assets are being amortized on a straight-line basis over their estimated useful lives.
There were no impairment losses recorded on finite-lived intangible assets during the three and six months ended June 30, 2024 and 2023. Updates to key assumptions used to calculate the fair value of the Company’s in-process research and development asset (“IPR&D”) could change the Company’s estimate that it will recover the carrying amount of the IPR&D asset in the near term.
17
EXACT SCIENCES CORPORATION
Notes to Condensed Consolidated Financial Statements
(Unaudited)
Goodwill
The change in the carrying amount of goodwill for the periods ended June 30, 2024 and December 31, 2023 is as follows:
(In thousands)
Balance, January 1, 2023
$2,346,040 
Resolution Bioscience acquisition
20,692 
Effects of changes in foreign currency exchange rates (1)388 
Balance, December 31, 2023
2,367,120 
Resolution Bioscience acquisition adjustment
205 
Effects of changes in foreign currency exchange rates (1)(353)
Balance June 30, 2024
$2,366,972 
______________
(1)Represents the impact of foreign currency translation related to the goodwill acquired as a result of the acquisition of OmicEra.
There were no impairment losses for the three and six months ended June 30, 2024 and 2023.

(7) FAIR VALUE MEASUREMENTS
The three levels of the fair value hierarchy established are as follows:
Level 1    Quoted prices (unadjusted) in active markets for identical assets or liabilities that the Company has the ability to access as of the reporting date. Active markets are those in which transactions for the asset or liability occur in sufficient frequency and volume to provide pricing information on an ongoing basis.
Level 2    Pricing inputs other than quoted prices in active markets included in Level 1, which are either directly or indirectly observable as of the reporting date. These include quoted prices for similar assets or liabilities in active markets and quoted prices for identical or similar assets or liabilities in markets that are not active.
Level 3    Unobservable inputs that reflect the Company’s assumptions about the assumptions that market participants would use in pricing the asset or liability. Unobservable inputs shall be used to measure fair value to the extent that observable inputs are not available.
18
EXACT SCIENCES CORPORATION
Notes to Condensed Consolidated Financial Statements
(Unaudited)
The following table presents the Company’s fair value measurements as of June 30, 2024 along with the level within the fair value hierarchy in which the fair value measurements, in their entirety, fall.
(In thousands)Fair Value at June 30, 2024Quoted Prices in Active Markets for Identical Assets (Level 1)Significant Other Observable Inputs (Level 2)Significant Unobservable Inputs (Level 3)
Cash, cash equivalents, and restricted cash
Cash and money market$519,836 $519,836 $— $— 
U.S. government agency securities10,344 — 10,344 — 
Restricted cash (1)
5,837 5,837 — — 
Marketable securities
Corporate bonds$203,288 $— $203,288 $— 
U.S. government agency securities118,626 — 118,626 — 
Asset backed securities87,414 — 87,414 — 
Commercial paper4,943 — 4,943 — 
Equity securities2,331 2,331 — — 
Non-marketable securities$1,057 $— $— $1,057 
Liabilities
Contingent consideration$(277,921)$— $— $(277,921)
Total$675,755 $528,004 $424,615 $(276,864)
The following table presents the Company’s fair value measurements as of December 31, 2023 along with the level within the fair value hierarchy in which the fair value measurements, in their entirety, fall.
(In thousands)Fair Value at December 31, 2023Quoted Prices in Active Markets for Identical Assets (Level 1)Significant Other Observable Inputs (Level 2)Significant Unobservable Inputs (Level 3)
Cash, cash equivalents and restricted cash
Cash and money market$530,100 $530,100 $— $— 
Commercial paper72,243 — 72,243 — 
Restricted cash (1)
4,297 4,297 — — 
U.S. government agency securities3,035 — 3,035 — 
Marketable securities
U.S. government agency securities$56,716 $— $56,716 $— 
Corporate bonds55,828 — 55,828 — 
Asset backed securities34,897 — 34,897 — 
Commercial paper20,984 — 20,984 — 
Equity securities3,841 3,841 — — 
Non-marketable securities$7,650 $— $— $7,650 
Liabilities
Contingent consideration$(288,657)$— $— $(288,657)
Total$500,934 $538,238 $243,703 $(281,007)
_________________________________
(1)Restricted cash primarily represents cash held by a third-party financial institution as part of a cash collateral agreement related to the Company’s credit card program. The restrictions will lapse upon the termination of the agreements or the removal of the cash collateral requirement by the third-parties.
19
EXACT SCIENCES CORPORATION
Notes to Condensed Consolidated Financial Statements
(Unaudited)
There have been no material changes in valuation techniques or transfers between fair value measurement levels during the three and six months ended June 30, 2024. The fair value of Level 2 instruments classified as cash equivalents and marketable debt securities are valued using a third-party pricing agency where the valuation is based on observable inputs including pricing for similar assets and other observable market factors.
The Company has elected the fair value option under the income approach to measure certain Level 3 non-marketable securities. Gains and losses recorded on non-marketable securities are included in investment income, net in the condensed consolidated statement of operations. The following table provides a reconciliation of the beginning and ending balances of non-marketable securities valued using the fair value option:
(In thousands)Non-Marketable Securities
Beginning balance, January 1, 2024
$7,650 
Changes in fair value(343)
Settlement of non-marketable securities(6,250)
Ending balance, June 30, 2024
$1,057 
Contingent Consideration Liabilities
The fair value of the contingent consideration liabilities was $277.9 million and $288.7 million as of June 30, 2024 and December 31, 2023, respectively, of which $19.0 million was included in other current liabilities and $258.9 million was included in other long-term liabilities in the condensed consolidated balance sheet as of June 30, 2024. The contingent consideration liabilities were included in other long-term liabilities as of December 31, 2023.
The following table provides a reconciliation of the beginning and ending balances of contingent consideration:
(In thousands)Contingent Consideration
Beginning balance, January 1, 2024
$288,657 
Changes in fair value (1)(7,636)
Payments (2)
(3,100)
Ending balance, June 30, 2024
$277,921 
______________
(1)The change in fair value of the contingent consideration liability was an increase of $4.2 million and a reduction of $4.7 million for the three and six months ended June 30, 2023, respectively, which is included in general and administrative expenses in the condensed consolidated statement of operations.
(2)Payment was made in the second quarter of 2024 to settle the contingent consideration liability previously recorded related to the Company’s acquisition of OmicEra.
This fair value measurement of contingent consideration is categorized as a Level 3 liability, as the measurement amount is based primarily on significant inputs not observable in the market.
20
EXACT SCIENCES CORPORATION
Notes to Condensed Consolidated Financial Statements
(Unaudited)
The fair value of the contingent consideration liabilities recorded from the Company’s acquisitions of Thrive Earlier Detection Corporation (“Thrive”), Ashion Analytics, LLC (“Ashion”), and OmicEra related to regulatory and product development milestones was $277.9 million and $288.7 million as of June 30, 2024 and December 31, 2023, respectively. The Company evaluates the fair value of the expected contingent consideration and the corresponding liabilities related to the regulatory and product development milestones using the probability-weighted scenario based discounted cash flow model, which is consistent with the initial measurement of the expected contingent consideration liabilities. Probabilities of success are applied to each potential scenario and the resulting values are discounted using a present-value factor. The passage of time in addition to changes in projected milestone achievement timing, present-value factor, the degree of achievement, if applicable, and probabilities of success may result in adjustments to the fair value measurement. The fair value of the contingent consideration liability recorded related to regulatory and product development milestones was determined using a weighted average probability of success of 90% and 89% as of June 30, 2024 and December 31, 2023, respectively, and a weighted average present-value factor of 6.1% and 5.8% as of June 30, 2024 and December 31, 2023, respectively. The projected fiscal year of payment range is from 2025 to 2031. Unobservable inputs were weighted by the relative fair value of the contingent consideration liabilities.
The revenue milestone associated with the Ashion acquisition is not expected to be achieved and therefore no liability has been recorded for this milestone.
Non-Marketable Equity Investments
Non-marketable equity securities without readily determinable fair values, which are classified as a component of other long-term assets, net, had the following cumulative upward and downward adjustments and aggregate carrying amounts:
(In thousands)
June 30, 2024June 30, 2023
Cumulative upward adjustments (1)
$5,102 $779 
Cumulative downward adjustments and impairments (2)
15,071 12,528 
Aggregate carrying value (3)
52,227 34,197 
_________________________________
(1)    There were no material upward adjustments recorded on non-marketable equity securities held for the three and six months ended June 30, 2024 and 2023.
(2)    There were no material downward adjustments or impairments recorded on non-marketable equity securities held for the three and six months ended June 30, 2024 and 2023, respectively.
(3)    The aggregate carrying value of non-marketable equity securities was $46.0 million as of December 31, 2023.
There were no material realized gains or losses recorded during the three and six months ended June 30, 2024 and 2023.
The Company has committed capital to venture capital investment funds of $18.0 million, of which $11.8 million remains callable through 2033 as of June 30, 2024. The aggregate carrying amount of these funds, which are classified as a component of other long-term assets, net in the Company’s condensed consolidated balance sheets, were $6.8 million and $5.2 million as of June 30, 2024 and December 31, 2023, respectively.
Derivative Financial Instruments
The Company enters into foreign currency forward contracts on the last day of each month to mitigate the impact of adverse movements in foreign exchange rates related to the remeasurement of monetary assets and liabilities and hedge the Company’s foreign currency exchange rate exposure. As of June 30, 2024 and December 31, 2023 the Company had open foreign currency forward contracts with notional amounts of $45.2 million and $39.5 million, respectively. The Company's foreign exchange derivative instruments are classified as Level 2 within the fair value hierarchy as they are valued using inputs that are observable in the market or can be derived principally from or corroborated by observable market data. The fair value of the open foreign currency forward contracts was zero at June 30, 2024 and December 31, 2023 and there were no gains or losses recorded to adjust the fair value of the open foreign currency contract held as of June 30, 2024. The contracts are closed subsequent to each month-end, and the gains and losses recorded from the contracts were not significant for the three and six months ended June 30, 2024 and 2023.
21
EXACT SCIENCES CORPORATION
Notes to Condensed Consolidated Financial Statements
(Unaudited)

(8) LONG-TERM DEBT
Accounts Receivable Securitization Facility
On June 29, 2022, the Company, through a wholly-owned special purpose entity, Exact Receivables LLC (“Exact Receivables”) entered into an accounts receivable securitization program (the “Securitization Facility”) with PNC Bank, National Association (“PNC”), with a scheduled maturity date of June 29, 2024. The Securitization Facility provided Exact Receivables with a revolving line-of-credit of up to $150.0 million of borrowing capacity, subject to certain borrowing base requirements, by collateralizing a security interest in the domestic customer accounts receivable of certain wholly-owned subsidiaries of the Company. The amount available under the Securitization Facility fluctuated over time based on the total amount of eligible customer accounts receivable generated by the Company during the normal course of operations. The Securitization Facility required the Company to maintain minimum borrowings under the facility of $50.0 million. The debt issuance costs incurred related to the Securitization Facility were not significant and were amortized over the life of the Securitization Facility through interest expense within the condensed consolidated statements of operations.
In connection with the Securitization Facility, the Company also entered into two Receivables Purchase Agreements (“Receivable Purchase Agreements”) on June 29, 2022. The Receivable Purchase Agreements were among the Company and certain wholly-owned subsidiaries of the Company, and between the Company and Exact Receivables. Under the agreements, the wholly-owned subsidiaries sold all of their right, title and interest in their accounts receivables to Exact Receivables. The receivables were used to collateralize borrowings made under the Securitization Facility. The Company retained the responsibility of servicing the accounts receivable balances pledged as collateral under the Securitization Facility and provided a performance guaranty.
Upon the maturity of the Securitization Facility in June 2024, the Company repaid the previously outstanding balance of $50.0 million in full. As of December 31, 2023, the Company had an outstanding balance of $50.0 million, which was included in debt, current portion on the Company’s condensed consolidated balance sheet. Prior to the repayment, the outstanding balance accrued interest at a rate equal to a daily secured overnight financing rate (“SOFR”) plus a SOFR adjustment and an applicable margin. The interest rate was 6.89% as of the maturity date.
Revolving Loan Agreement
During November 2021, the Company entered into a revolving loan agreement (the “Revolving Loan Agreement”) with PNC. The Revolving Loan Agreement provides the Company with a revolving line of credit of up to $150.0 million (the “Revolver”). The Revolver is collateralized by the Company’s marketable securities held by PNC, which must continue to maintain a minimum market value of $150.0 million. The Revolver is available for general working capital purposes and all other lawful corporate purposes. In addition, the Company may request, in lieu of cash advances, letters of credit with an aggregate stated amount outstanding not to exceed $20.0 million. The availability of advances under the line of credit will be reduced by the stated amount of each letter of credit issued and outstanding.
Borrowings under the Revolving Loan Agreement accrue interest at an annual rate equal to the sum of the daily Bloomberg Short-Term Bank Yield Index Rate plus the applicable margin of 0.60%. Loans under the Revolving Loan Agreement may be prepaid at any time without penalty. In October 2022, the Revolving Loan Agreement was amended to extend the maturity date from November 5, 2023 to November 5, 2025. There were no other amendments to the Revolver.
The Company has agreed to various financial covenants under the Revolving Loan Agreement, and as of June 30, 2024, the Company is in compliance with all covenants.
In December 2021 and January 2023, PNC issued letters of credit of $2.9 million and $1.5 million, respectively, which reduced the amount available for cash advances under the line of credit to $145.6 million as of June 30, 2024 and December 31, 2023. As of June 30, 2024 and December 31, 2023, the Company has not drawn funds from, nor are any amounts outstanding under, the Revolving Loan Agreement.

22
EXACT SCIENCES CORPORATION
Notes to Condensed Consolidated Financial Statements
(Unaudited)
(9) CONVERTIBLE NOTES
Convertible note obligations included in the condensed consolidated balance sheet consisted of the following as of June 30, 2024:
Fair Value (1)
(In thousands)Principal AmountUnamortized Debt Discount and Issuance CostsNet Carrying AmountAmountLeveling
2031 Convertible Notes - 1.750%
$620,709 $(14,633)$606,076 $510,335 2
2030 Convertible Notes - 2.000%
572,993 (3,998)568,995 513,373 2
2028 Convertible Notes - 0.375%
589,380 (5,741)583,639 482,702 2
2027 Convertible Notes - 0.375%
563,822 (4,584)559,238 494,872 2
2025 Convertible Notes - 1.000% (2)
249,172 (249)248,923 242,943 2
Convertible note obligations included in the condensed consolidated balance sheet consisted of the following as of December 31, 2023:
Fair Value (1)
(In thousands)Principal AmountUnamortized Debt Discount and Issuance CostsNet Carrying AmountAmountLeveling
2030 Convertible Notes - 2.000%
$572,993 $(4,349)$568,644 $684,475 2
2028 Convertible Notes - 0.375%
949,042 (10,499)938,543 887,354 2
2027 Convertible Notes - 0.375%
563,822 (5,429)558,393 549,839 2
2025 Convertible Notes - 1.000%
249,172 (476)248,696 293,300 2
______________
(1)The fair values are based on observable market prices for this debt, which is traded in less active markets and therefore is classified as a Level 2 fair value measurement.
(2)The Company’s convertible notes due in 2025 (the “2025 Notes”) mature on January 15, 2025 and are included in convertible notes, net, current portion on the condensed consolidated balance sheet as of June 30, 2024. The 2025 Notes were included in convertible notes, net, less current portion as of December 31, 2023.
Issuances and Settlements
In February 2023, the Company entered into a privately negotiated exchange and purchase agreement with a single holder of certain of the Company’s convertible notes due in 2027 (the “2027 Notes”) and 2028 (the “2028 Notes”). The Company issued the holder $500.0 million aggregate principal amount of 2.0% Convertible Notes due in 2030 (the “2030 Notes”) in exchange for $183.7 million of aggregate principal of 2027 Notes, $201.0 million of aggregate principal of 2028 Notes, and $138.0 million of cash. The extinguishment resulted in a gain on settlement of convertible notes of $17.7 million, which is included in interest income (expense), net in the condensed consolidated statement of operations for the six months ended June 30, 2023. The gain represents the difference between (i) the fair value of the consideration transferred and (ii) the carrying value of the debt at the time of exchange.
In March 2023, the Company entered into a privately negotiated exchange agreement with two holders of certain of the 2025 Notes. The Company issued the holder $73.0 million aggregate principal amount of 2030 Notes in exchange for $65.8 million of aggregate principal of 2025 Notes. The extinguishment resulted in a loss on settlement of convertible notes of $7.4 million, which is included in interest income (expense), net in the condensed consolidated statement of operations for the six months ended June 30, 2023. The loss represents the difference between (i) the fair value of the consideration transferred and (ii) the carrying value of the debt at the time of exchange.
23
EXACT SCIENCES CORPORATION
Notes to Condensed Consolidated Financial Statements
(Unaudited)
The net proceeds from the issuance of the 2030 Notes were approximately $133.0 million, after deducting commissions and offering expenses payable by the Company.
The 2030 Notes will mature on March 1, 2030 and bear interest at a rate of 2.0% per year, payable semi-annually in arrears on March 1 and September 1 of each year, beginning on September 1, 2023.
In April 2024, the Company entered into a privately negotiated exchange and purchase agreement with certain holders of the Company’s 2028 Notes. The Company issued $620.7 million aggregate principal amount of 1.75% Convertible Notes due in 2031 (the “2031 Notes” and, collectively with the 2025 Notes, 2027 Notes, 2028 Notes, and 2030 Notes, the “Notes”) in exchange for $359.7 million of aggregate principal of 2028 Notes, and $266.8 million of cash after deducting underwriting discounts. The extinguishment resulted in a gain on settlement of convertible notes of $10.3 million, which is included in interest income (expense), net in the condensed consolidated statement of operations for the three and six months ended June 30, 2024. The gain represents the difference between (i) the fair value of the consideration transferred and (ii) the carrying value of the debt at the time of exchange.
The net proceeds from the issuance of the 2031 Notes were approximately $259.8 million, after deducting commissions and offering expenses payable by the Company.
The 2031 Notes will mature on April 15, 2031 and bear interest at a rate of 1.75% per year, payable semi-annually in arrears on October 15 and April 15 of each year, beginning on October 15, 2024. The Company has the ability to repurchase the 2031 Notes after April 17, 2029 upon the occurrence of certain events and during certain periods, as set forth in the Indenture filed at the time of the offering.
Summary of Conversion Features
Until the six-months immediately preceding the maturity date of the applicable series of the Company’s convertible notes, each series of Notes is convertible only upon the occurrence of certain events and during certain periods, as set forth in the Indentures filed at the time of the original offerings. On or after the date that is six-months immediately preceding the maturity date of the applicable series of Notes until the close of business on the second scheduled trading day immediately preceding the maturity date, holders may convert such Notes at any time. The Notes will be convertible into cash, shares of the Company’s common stock (plus, if applicable, cash in lieu of any fractional share), or a combination of cash and shares of the Company’s common stock, at the Company’s election.
It is the Company’s intent to settle all conversions through combination settlement. The initial conversion rate is 13.26, 8.96, 8.21, 12.37, and 10.06 shares of common stock per $1,000 principal amount for the 2025 Notes, 2027 Notes, 2028 Notes, 2030 Notes, and 2031 Notes, respectively, which is equivalent to an initial conversion price of approximately $75.43, $111.66, $121.84, $80.83, and $99.36 per share of the Company’s common stock for the 2025 Notes, 2027 Notes, 2028 Notes, 2030 Notes, and 2031 Notes, respectively. The 2025 Notes, 2027 Notes, 2028 Notes, 2030 Notes, and 2031 Notes are potentially convertible into up to 3.3 million, 5.0 million, 4.8 million, 7.1 million, and 6.2 million shares, respectively. The conversion rate is subject to adjustment upon the occurrence of certain specified events as set forth in the Indentures filed at the time of the original offerings but will not be adjusted for accrued and unpaid interest. In addition, holders of the Notes who convert their Notes in connection with a “make-whole fundamental change” (as defined in the Indentures), will, under certain circumstances, be entitled to an increase in the conversion rate.
If the Company undergoes a “fundamental change” (as defined in the Indentures), holders of the Notes may require the Company to repurchase for cash all or part of their Notes at a repurchase price equal to 100% of the principal amount of the Notes to be repurchased, plus accrued and unpaid interest.
Based on the closing price of the Company’s common stock of $42.25 on June 30, 2024, the if-converted values on the Notes do not exceed the principal amount.
The Notes do not contain any financial or operating covenants or any restrictions on the payment of dividends, the issuance of other indebtedness, or the issuance or repurchase of securities by the Company.
24
EXACT SCIENCES CORPORATION
Notes to Condensed Consolidated Financial Statements
(Unaudited)
Ranking of Convertible Notes
The Notes are the Company’s senior unsecured obligations and (i) rank senior in right of payment to all of its future indebtedness that is expressly subordinated in right of payment to the Notes; (ii) rank equal in right of payment to each outstanding series thereof and to all of the Company’s future liabilities that are not so subordinated, unsecured indebtedness; (iii) are effectively junior to all of the Company’s existing and future secured indebtedness and other secured obligations, to the extent of the value of the assets securing that indebtedness and other secured obligations; and (iv) are structurally subordinated to all indebtedness and other liabilities of the Company’s subsidiaries.
Issuance Costs
Issuance costs are amortized to interest expense over the term of the Notes. The following table summarizes the original issuance costs at the time of issuance for each set of Notes:
(In thousands)
2031 Convertible Notes
$6,820 
2030 Convertible Notes4,938 
2028 Convertible Notes24,453 
2027 Convertible Notes14,285 
2025 Convertible Notes17,646 
Interest Expense
Interest expense on the Notes includes the following:
Three Months Ended June 30,Six Months Ended June 30,
(In thousands)2024202320242023
Debt issuance costs amortization$1,316 $1,315 $2,631 $2,692 
Debt discount amortization264 25 289 56 
Gain on settlements of convertible notes(10,254)— (10,254)(10,324)
Coupon interest expense6,863 4,906 11,770 8,260 
Total interest expense (income) on convertible notes$(1,811)$6,246 $4,436 $684 
The following table summarizes the effective interest rates of the Notes:
Three Months Ended June 30,Six Months Ended June 30,
2024202320242023
2031 Convertible Notes
2.06 %— %2.06 %— %
2030 Convertible Notes2.12 %2.12 %2.10 %2.10 %
2028 Convertible Notes0.64 %0.64 %0.63 %0.63 %
2027 Convertible Notes0.67 %0.67 %0.67 %0.67 %
2025 Convertible Notes1.18 %1.18 %1.17 %1.18 %
The remaining period over which the unamortized debt discount will be recognized as non-cash interest expense is 0.55, 2.71, 3.67, 5.67, and 6.79 years for the 2025 Notes, 2027 Notes, 2028 Notes, 2030 Notes, and 2031 Notes, respectively.

25
EXACT SCIENCES CORPORATION
Notes to Condensed Consolidated Financial Statements
(Unaudited)
(10) LICENSE AND COLLABORATION AGREEMENTS
The Company licenses certain technologies that are, or may be, incorporated into its technology under several license agreements, as well as the rights to commercialize certain diagnostic tests through collaboration agreements. Generally, the license agreements require the Company to pay single-digit royalties based on net revenues received using the technologies and may require minimum royalty amounts, milestone payments, or maintenance fees.
Mayo Foundation for Medical Education and Research
In June 2009, the Company entered into an exclusive, worldwide license agreement with the Mayo Foundation for Medical Education and Research (“Mayo”), under which Mayo granted the Company an exclusive, worldwide license to certain Mayo patents and patent applications, as well as a non-exclusive, worldwide license with regard to certain Mayo know-how. The scope of the license covers any screening, surveillance or diagnostic test or tool for use in connection with any type of cancer, pre-cancer, disease or condition. The Company’s license agreement with Mayo was most recently amended and restated in September 2020.
The licensed Mayo patents and patent applications contain both method and composition claims that relate to sample processing, analytical testing and data analysis associated with nucleic acid screening for cancers and other diseases. The jurisdictions covered by these patents and patent applications include the U.S., Australia, Canada, the European Union, China, Japan and Korea. Under the license agreement, the Company assumed the obligation and expense of prosecuting and maintaining the licensed Mayo patents and is obligated to make commercially reasonable efforts to bring to market products using the licensed Mayo intellectual property.
Pursuant to the Company’s agreement with Mayo, the Company is required to pay Mayo a low-single-digit royalty on the Company’s net sales of current and future products using the licensed Mayo intellectual property each year during the term of the Mayo agreement.
The Company is also required to pay Mayo up to $3.0 million in sales-based milestone payments upon cumulative net sales of each product using the licensed Mayo intellectual property reaching specified levels.
The license agreement will remain in effect, unless earlier terminated by the parties in accordance with the agreement, until the last of the licensed patents expires in 2039 (or later, if certain licensed patent applications are issued). However, if the Company is still using the licensed Mayo know-how or certain Mayo-provided biological specimens or their derivatives on such expiration date, the term shall continue until the earlier of the date the Company stops using such know-how and materials and the date that is five years after the last licensed patent expires. The license agreement contains customary termination provisions and permits Mayo to terminate the license agreement if the Company sues Mayo or its affiliates, other than any such suit claiming an uncured material breach by Mayo of the license agreement.
In addition to granting the Company a license to the covered Mayo intellectual property, Mayo provides the Company with product development and research and development assistance pursuant to the license agreement and other collaborative arrangements. In September 2020, Mayo also agreed to make available certain personnel to provide such assistance through January 2025. In connection with this collaboration, the Company has incurred insignificant charges for the three months ended June 30, 2024 and 2023, respectively. The charges incurred in connection with this collaboration are recorded in research and development expenses in the Company’s condensed consolidated statements of operations.
Johns Hopkins University
Through the acquisition of Thrive, the Company acquired a worldwide exclusive license agreement with Johns Hopkins University (“JHU”) for use of several JHU patents and licensed know-how. The license is designed to enable the Company to leverage JHU proprietary data in the development and commercialization of a blood-based, multi-cancer screening test. The agreement terms would require the Company to pay single-digit sales-based royalties and up to $45.0 million in sales-based milestone payments if net sales of a licensed product using JHU proprietary data reach specified levels. The Company will record the sales-based royalties and sales-based milestones once achievement is deemed probable. The Company has not incurred charges related to the achievement of any sales-based royalties or sales-based milestones as of June 30, 2024.
26
EXACT SCIENCES CORPORATION
Notes to Condensed Consolidated Financial Statements
(Unaudited)
Targeted Digital Sequencing (“TARDIS”) License Agreement
In January 2021, the Company entered into an exclusive, worldwide license to the proprietary TARDIS technology from The Translational Genomics Research Institute (“TGen”). Under the agreement, the Company acquired a royalty-free, worldwide exclusive license to proprietary TARDIS patents and know-how. Under the agreement, the Company was obligated to make milestone payments to TGen of up to $45.0 million in sales-based milestone payments upon cumulative net sales related to molecular residual disease (“MRD”) detection and/or treatment reaching specified levels. These payments were contingent upon achievement of these cumulative revenues on or before December 31, 2030, which was not achieved prior to the termination.
Effective May 1, 2024, the Company entered into termination agreements (the “Termination Agreements”) with TGen for the purpose of terminating the license and sponsored research agreement relating to the TARDIS technology and an additional sponsored research agreement with a broader scope (collectively, the “Original Agreements”). As part of the Termination Agreements, the Company will pay TGen $27.6 million in compensation for the termination of the Original Agreements, which will be allocated into three annual installments of $9.2 million per year beginning in the second quarter of 2024. The fair value of the termination payments as of the date of the Termination Agreements was $25.8 million, which was recorded as research and development expense in the condensed consolidated statement of operations for the three and six months ended June 30, 2024. The remaining $1.8 million in expense will be amortized on a straight-line basis through the date of the final payment in the second quarter of 2026. The Company has recorded a liability of $16.8 million representing the fair value of the remaining payments, of which $8.7 million is included in accrued liabilities and $8.1 million is included in other long-term liabilities on the condensed consolidated balance sheet as of June 30, 2024. The termination payments eliminate the Company’s obligation to pay TGen any further payments, equities, fees, costs, or other amounts that would have been due under the Original Agreements, including the milestone payments. The Company’s ongoing development efforts for its pipeline tests are not impacted by the Termination Agreements.
Broad Institute, Inc.
In June 2023, the Company entered into an exclusive license agreement with Broad Institute, Inc. (“Broad Institute”) to utilize the Minor Allele Enriched Sequencing Through Recognition Oligonucleotides (“MAESTRO”) technology in the Company’s MRD testing. Under the license agreement, the Company is obligated to make development milestone payments to Broad Institute of up to $6.5 million upon achievement of certain development milestones related to prospective MRD tests that use the MAESTRO technology. In addition, the Company is obligated to make sales-based milestone payments to Broad Institute that equate up to a mid-single-digit royalty upon the achievement of certain cumulative net sales targets of licensed products using the MAESTRO technology beginning at $500.0 million. The Company will record the development milestones once achieved and the sales milestones once achievement is deemed probable. The Company has not incurred charges related to the achievement of development milestones or sales milestones as of June 30, 2024.
Watchmaker Genomics, Inc.
In July 2023, the Company entered into a co-exclusive development and license agreement with Watchmaker Genomics, Inc. (“Watchmaker”) under which the Company granted Watchmaker a co-exclusive license to the non-bisulfite technology for the detection of methylated DNA and other epigenetic modifications (“TAPS”). TAPS is based on patents obtained by the Company through an exclusive license agreement with the Ludwig Institute for Cancer Research. Under the agreement, both parties have the right to use and develop TAPS for commercial purposes. The Company has the potential to receive up to $82.0 million in sales-based milestone payments and mid-single digit royalties based on future Watchmaker net sales of licensed products including TAPS. Additionally, Watchmaker has the right to sublicense TAPS, and the Company has the potential to receive royalties based on future Watchmaker sublicense receipts.

27
EXACT SCIENCES CORPORATION
Notes to Condensed Consolidated Financial Statements
(Unaudited)
(11) STOCKHOLDERS’ EQUITY
Changes in Accumulated Other Comprehensive Income (Loss)
The amounts recognized in AOCI for the six months ended June 30, 2024 were as follows:
(In thousands)Cumulative Translation AdjustmentUnrealized Gain (Loss) on Securities (1)
AOCI
Balance at December 31, 2023$1,374 $54 $1,428 
Other comprehensive loss before reclassifications
(1,446)(984)(2,430)
Amounts reclassified from accumulated other comprehensive income (loss)
— 59 59 
Net current period change in accumulated other comprehensive income (loss)
(1,446)(925)(2,371)
Balance at June 30, 2024$(72)$(871)$(943)
______________
(1)There was no tax impact from the amounts recognized in AOCI for the three and six months ended June 30, 2024.
The amounts recognized in AOCI for the six months ended June 30, 2023 were as follows:
(In thousands)Cumulative Translation AdjustmentUnrealized Gain (Loss) on Securities (1)
AOCI
Balance at December 31, 2022$53 $(5,289)$(5,236)
Other comprehensive income before reclassifications
609 1,051 1,660 
Amounts reclassified from accumulated other comprehensive income (loss)
— 2,853 2,853 
Net current period change in accumulated other comprehensive income (loss)
609 3,904 4,513 
Balance at June 30, 2023$662 $(1,385)$(723)
______________
(1)There was no tax impact from the amounts recognized in AOCI for the six months ended June 30, 2023.
Amounts reclassified from AOCI for the six months ended June 30, 2024 and 2023 were as follows:
Affected Line Item in the
Statements of Operations		Six Months Ended June 30,
Details about AOCI Components (In thousands)20242023
Change in value of available-for-sale investments
Sales and maturities of available-for-sale investments
Investment income, net
$59 $2,853 
Total reclassifications$59 $2,853 

(12) STOCK-BASED COMPENSATION
Stock-Based Compensation Plans
The Company maintains the following plans for which awards were granted from or had awards outstanding in 2023: the 2010 Omnibus Long-Term Incentive Plan (as Amended and Restated effective July 27, 2017), the 2019 Omnibus Long-Term Incentive Plan, and the 2010 Employee Stock Purchase Plan. These plans are collectively referred to as the “Stock Plans” and are administered in conjunction with the Company’s Equity Award Death, Disability and Retirement Policy, which was adopted in February 2023. Refer to the Company’s 2023 Form 10-K for further information regarding this policy.
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EXACT SCIENCES CORPORATION
Notes to Condensed Consolidated Financial Statements
(Unaudited)
Stock-Based Compensation Expense
The Company records stock-based compensation expense in connection with the amortization of restricted stock and restricted stock unit awards (“RSUs”), performance share units (“PSUs”), stock purchase rights granted under the Company’s employee stock purchase plan (“ESPP”) and stock options granted to employees, non-employee consultants and non-employee directors. The Company recorded $56.6 million and $61.7 million in stock-based compensation expense during the three months ended June 30, 2024 and 2023, respectively. The Company recorded $116.9 million and $110.9 million in stock-based compensation expense during the six months ended June 30, 2024 and 2023, respectively.
As of June 30, 2024, there was approximately $450.0 million of expected total unrecognized compensation cost related to non-vested stock-based compensation arrangements granted under all equity compensation plans. The Company expects to recognize that cost over a weighted average period of 2.7 years.
Stock Options
A summary of stock option activity under the Stock Plans is as follows:
Option SharesWeighted Average Exercise PriceWeighted Average Remaining Contractual Term (Years)Aggregate Intrinsic Value (1)
(Aggregate intrinsic value in thousands)
Outstanding, January 1, 20241,286,173 $47.67 3.8
Exercised(141,503)15.44 
Forfeited(17,164)94.85 
Outstanding, June 30, 20241,127,506 $51.00 3.6$11,834 
Vested and expected to vest, June 30, 2024
1,127,506 $51.00 3.6$11,834 
Exercisable, June 30, 20241,127,506 $51.00 3.6$11,834 
______________
(1)The total intrinsic value of options exercised, net of shares withheld for taxes, during the six months ended June 30, 2024 and 2023 was $3.3 million and $7.0 million, respectively, determined as of the date of exercise.
Restricted Stock and Restricted Stock Units
The fair value of restricted stock and RSUs is determined on the date of grant using the closing stock price on that day.
A summary of restricted stock and RSU activity during the six months ended June 30, 2024 is as follows:
Restricted SharesWeighted Average Grant Date Fair Value (1)
Outstanding, January 1, 20246,272,763 $73.39 
Granted3,937,097 57.38 
Released (2)(1,924,514)79.93 
Forfeited(504,123)64.23 
Outstanding, June 30, 20247,781,223 $63.97 
______________
(1)The weighted average grant date fair value of the RSUs granted during the six months ended June 30, 2023 was $60.94.
(2)The fair value of RSUs vested and converted to shares of the Company’s common stock was $153.4 million and $130.5 million during the six months ended June 30, 2024 and 2023, respectively.
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EXACT SCIENCES CORPORATION
Notes to Condensed Consolidated Financial Statements
(Unaudited)
Performance Share Units
The Company has issued performance-based equity awards to certain employees which vest upon the achievement of certain performance goals, including financial performance targets and operational milestones.
A summary of PSU activity during the six months ended June 30, 2024 is as follows:
Performance Share Units (1)Weighted Average Grant Date Fair Value (2)
Outstanding, January 1, 20241,597,801 $92.73 
Granted913,533 63.68 
Released (3)(70,662)140.20 
Forfeited(336,852)106.06 
Outstanding, June 30, 20242,103,820 $74.25 
______________
(1)The PSUs listed above assumes attainment of maximum payout rates as set forth in the performance criteria. Applying actual or expected payout rates, the number of outstanding PSUs as of June 30, 2024 was 1,037,206.
(2)The weighted average grant date fair value of the PSUs granted during the six months ended June 30, 2023 was $79.17.
(3)The fair value of PSUs vested and converted to shares of the Company’s common stock was $9.9 million and $1.0 million for the six months ended June 30, 2024 and 2023, respectively.
Employee Stock Purchase Plan
The fair value of shares purchased during the three and six months ended June 30, 2024 and 2023 under the ESPP is based on the assumptions in the following table:
Three Months Ended June 30,Six Months Ended June 30,
2024202320242023
ESPP Shares
Risk-free interest rates
4.71% - 5.30%
4.68%
4.71% - 5.30%
4.68%
Expected term (in years)1.171.251.171.25
Expected volatility
55.67% - 63.13%
67.30%
55.67% - 63.13%
67.30%
Dividend yield
—%
—%—%—%
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EXACT SCIENCES CORPORATION
Notes to Condensed Consolidated Financial Statements
(Unaudited)
(13) COMMITMENTS AND CONTINGENCIES
Leases
Supplemental disclosure of cash flow information related to the Company’s cash and non-cash activities with its leases are as follows:
Six Months Ended June 30,
(In thousands)20242023
Cash paid for amounts included in the measurement of lease liabilities:
Operating cash flows from operating leases$19,188$19,093
Operating cash flows from finance leases612342
Finance cash flows from finance leases3,0251,561
Non-cash investing and financing activities:
Right-of-use assets obtained in exchange for new operating lease liabilities (1)$18,925$(5,375)
Right-of-use assets obtained in exchange for new finance lease liabilities13,7172,670
Weighted-average remaining lease term - operating leases (in years)7.737.20
Weighted-average remaining lease term - finance leases (in years)3.213.04
Weighted-average discount rate - operating leases6.55 %6.41 %
Weighted-average discount rate - finance leases6.78 %7.03 %
______________
(1)For the six months ended June 30, 2023, this includes reductions of $8.6 million on the carrying value of the right-of-use assets held due to a reduction of the expected lease term.
As of June 30, 2024 and December 31, 2023, the Company’s right-of-use assets from operating leases are $139.8 million and $143.7 million, respectively, which are reported in operating lease right-of-use assets in the Company’s condensed consolidated balance sheets. As of June 30, 2024, the Company has outstanding operating lease obligations of $194.8 million, of which $27.1 million is reported in operating lease liabilities, current portion and $167.7 million is reported in operating lease liabilities, less current portion in the Company’s condensed consolidated balance sheets. As of December 31, 2023, the Company had outstanding operating lease obligations of $190.4 million, of which $29.4 million is reported in operating lease liabilities, current portion and $161.1 million is reported in operating lease liabilities, less current portion in the Company’s condensed consolidated balance sheets.
As of June 30, 2024 and December 31, 2023, the Company’s right-of-use assets from finance leases are $21.4 million and $11.3 million, respectively, which are reported in other long-term assets, net in the Company’s condensed consolidated balance sheets. As of June 30, 2024, the Company has outstanding finance lease obligations of $22.3 million, of which $7.3 million is reported in other current liabilities and $15.0 million is reported in other long-term liabilities in the Company’s condensed consolidated balance sheets. As of December 31, 2023, the Company had outstanding finance lease obligations of $11.9 million, of which $4.4 million is reported in other current liabilities and $7.5 million is reported in other long-term liabilities in the Company’s condensed consolidated balance sheets.

Legal Matters
In addition to commitments and obligations incurred in the ordinary course of business, from time to time the Company may be subject to a variety of claims and legal proceedings, including legal actions for damages, governmental investigations and other matters. The Company has also instituted, and may in the future institute, additional legal proceedings to enforce its rights and seek remedies, such as monetary damages, injunctive relief and declaratory relief.
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EXACT SCIENCES CORPORATION
Notes to Condensed Consolidated Financial Statements
(Unaudited)
The Company accrues costs for certain legal proceedings and regulatory matters to the extent that it determines an unfavorable outcome is probable and the amount of the loss can be reasonably estimated. While such accrued costs reflect the Company’s best estimate of the probable loss for such matters, the recorded amounts may differ materially from the actual amount of any such losses. In some cases, no estimate of the possible loss or range of loss in excess of amounts accrued, if any, can be made because of the inherently unpredictable nature of legal and regulatory proceedings, which may be exacerbated by various factors, including but not limited to, that they may involve indeterminate claims for monetary damages or may involve fines, penalties or punitive damages; present novel legal theories or legal uncertainties; involve disputed facts; represent a shift in regulatory policy; involve a large number of parties, claimants or regulatory bodies; are in the early stages of the proceedings; involve a number of separate proceedings and/or a wide range of potential outcomes; or result in a change of business practices.
As of the date of this Quarterly Report on Form 10-Q, amounts accrued for legal proceedings and regulatory matters were not material. The Company believes that the ultimate outcome of any of the regulatory and legal proceedings that are currently pending against it should not have a material adverse effect on financial condition, results of operations, cash flow or liquidity. However, it is possible that in a particular quarter or annual period the Company’s financial condition, results of operations, cash flow and/or liquidity could be materially adversely affected by an ultimate unfavorable resolution of, or development in, legal and/or regulatory proceedings.
Refer to the Company’s 2023 Form 10-K for detailed disclosures on legal matters that were settled in 2023.
Intellectual Property Litigation Matters
In May 2023, after receiving a cease-and-desist letter from the Company regarding its patent infringement, Geneoscopy Inc. (“Geneoscopy”) requested a reexamination of the Company’s U.S. Patent No. 11,634,781 (the “’781 Patent”) by the United States Patent and Trademark Office (the “USPTO”). Upon completion of the reexamination in October 2023, the USPTO rejected Geneoscopy’s challenge. In November 2023, the Company filed suit against Geneoscopy in the United States District Court for the District of Delaware, alleging that certain of Geneoscopy’s products infringe the ‘781 Patent and seeking unspecified monetary damages and injunctive relief (the “’781 Action”) and in May 2024, the Company filed a second complaint against Geneoscopy alleging infringement of the Company’s U.S. Patent No. 11,970,746 (the “’746 Action”). On June 28,2024, Geneoscopy filed counterclaims against the Company challenging the validity of the patents at issue and alleging breach of contract, misappropriation of trade secrets, unfair competition, and other violations of state and federal law seeking unspecified monetary damages and injunctive relief. On July 17, 2024, the Company filed a motion for preliminary injunction seeking an order prohibiting Geneoscopy from selling its infringing Colosense test in the United States.
In January 2024, Geneoscopy petitioned the USPTO to institute an inter partes review (“IPR”) challenging the validity of the ‘781 Patent before the Patent Trial and Appeals Board (“PTAB”). The PTAB is expected decide on or before July 30, 2024 whether it will institute the IPR. If the IPR is instituted, the Company intends to defend the validity of the ‘781 Patent, and a final decision of that review will be made on or before July 30, 2025.

(14) WISCONSIN ECONOMIC DEVELOPMENT TAX CREDITS
During December 2021, the Company entered into an amended agreement (“Amended WEDC Agreement”) with the Wisconsin Economic Development Corporation (“WEDC”) to earn an additional $18.5 million in refundable tax credits on the condition that the Company expends $350.0 million in capital investments and establishes and maintains 1,300 additional full-time positions over a five-year period. The capital investment credits are earned at a rate of 10% of eligible capital investments up to a maximum of $7.0 million, while the jobs creation credits are earned annually pursuant to the agreement.
The tax credits earned are first applied against the tax liability otherwise due, and if there is no such liability present, the claim for tax credits will be reimbursed in cash to the Company. The maximum amount of the refundable tax credit to be earned for each year is fixed, and the Company earns the credits by meeting certain capital investment and job creation thresholds over the term of the agreement. Should the Company earn and receive the job creation tax credits but not maintain those full-time positions through the end of the agreement, the Company may be required to pay those credits back to the WEDC.
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EXACT SCIENCES CORPORATION
Notes to Condensed Consolidated Financial Statements
(Unaudited)
The Company records the earned tax credits as job creation and capital investments occurs. The tax credits earned from capital investment are recognized as a reduction to capital expenditures at the time the costs are incurred, and then as an offset to depreciation expense over the expected life of the acquired capital assets. The tax credits earned related to job creation are recognized as an offset to operational expenses in the period in which the credits are earned.
As of June 30, 2024, the Company has earned $14.3 million of the refundable tax credits under the Amended WEDC Agreement. The unpaid portion is $8.8 million, of which $4.2 million is reported in prepaid expenses and other current assets and $4.6 million is reported in other long-term assets, net in the Company’s condensed consolidated balance sheets reflecting when collection of the refundable tax credits is expected to occur. During the three and six months ended June 30, 2024 and 2023, the amounts recorded as an offset to capital expenditures and operating expenses for the tax credits earned were not significant.
(15) ACQUISITIONS AND DIVESTITURES
Business Combinations
Resolution Bioscience, Inc.
On September 12, 2023, the Company completed the acquisition of all of the outstanding capital stock of Resolution Bioscience, Inc. (“Resolution Bioscience”) from Agilent Technologies, Inc. Resolution Bioscience develops and commercializes next-generation sequencing-based precision oncology solutions through its Clinical Laboratory Improvement Amendments (“CLIA”) certified lab based in Kirkland, Washington. The acquisition provides the Company with a high-quality blood-based therapy selection platform, complementing its comprehensive, tissue-based OncoExTra® test.
Refer to the Company’s 2023 Form 10-K for detailed disclosures on the combination, including the fair value of the consideration transferred, purchase price allocation, and goodwill and intangible assets identified in the transaction. During the three and six months ended June 30, 2024, there were no significant changes to the purchase price and purchase price allocation. The measurement period remains open pending the completion of valuation procedures related to certain acquired assets and liabilities assumed, primarily in connection with the developed technology intangible asset.
Divestitures
Oncotype DX Genomic Prostate Score Test
On August 2, 2022, pursuant to an asset purchase agreement (the “Asset Purchase Agreement”) with MDxHealth SA (“MDxHealth”), the Company completed the sale of the intellectual property and know-how related to the Company’s Oncotype DX Genomic Prostate Score test (“GPS test”), which will allow the Company to focus on the highest impact projects core to the Company’s vision. On August 23, 2023, the Company and MDxHealth executed the Second Amendment to the Asset Purchase Agreement (the “Second Amendment”). Under the Second Amendment, the Company agreed to allow MDxHealth to defer the 2023 contingent consideration payment by three years in exchange for additional consideration and more favorable contingent consideration terms, including elimination of the minimum revenue thresholds previously required to be met under the Asset Purchase Agreement. Refer to the Company’s 2023 Form 10-K for additional details on the agreements.
As of June 30, 2024 and December 31, 2023, a portion of the contingent consideration is classified as a contract asset. As of June 30, 2024, the contract asset was $45.2 million, of which $24.1 million is included in prepaid expenses and other current assets and $21.1 million is included in other long-term assets, net on the condensed consolidated balance sheet. As of December 31, 2023, the contract asset was $41.7 million, which is included in other long-term assets on the condensed consolidated balance sheet. The contract asset was estimated using historical GPS test revenues by MDxHealth under the most likely method. The remaining consideration balance as of June 30, 2024 and December 31, 2023 was $31.6 million, which includes the amount earned during the 2023 earnout year and is classified as a receivable within other long-term assets, net on the condensed consolidated balance sheet. The Company recorded an insignificant contingent consideration gain for the three and six months ended June 30, 2024, which is included in other operating income in the condensed consolidated statement of operations.
33
EXACT SCIENCES CORPORATION
Notes to Condensed Consolidated Financial Statements
(Unaudited)
(16) SEGMENT INFORMATION
Management determined that the Company functions as a single operating segment, and thus reports as a single reportable segment. This operating segment is focused on the development and global commercialization of clinical laboratory services allowing healthcare providers and patients to make individualized treatment decisions. Management assessed the financial information routinely reviewed by the Company's Chief Operating Decision Maker, its President and Chief Executive Officer, to monitor the Company's operating performance and support decisions regarding allocation of resources to its operations. Performance is continuously monitored at the consolidated level to timely identify deviations from expected results.
The following table summarizes total revenue from customers by geographic region. Product revenues are attributed to countries based on ship-to location.
Three Months Ended June 30,Six Months Ended June 30,
(In thousands)2024202320242023
United States$652,542 $586,507 $1,245,533 $1,151,689 
Outside of United States46,722 35,586 91,255 72,854 
Total revenues$699,264 $622,093 $1,336,788 $1,224,543 
Long-lived assets located in countries outside of the U.S. are not significant.

(17) INCOME TAXES
The Company recorded income tax expense of $1.5 million and $1.1 million for the three months ended June 30, 2024 and 2023, respectively. The Company recorded income tax expense of $3.3 million and $2.8 million for the six months ended June 30, 2024 and 2023, respectively. The Company’s income tax expense recorded during the three and six months ended June 30, 2024 is primarily related to current foreign and state tax expense. A deferred tax liability of $19.1 million and $17.3 million was recorded as of June 30, 2024 and December 31, 2023, respectively, which is included in other long-term liabilities on the Company’s condensed consolidated balance sheet. The Company continues to maintain a full valuation allowance against its deferred tax assets based on management’s determination that it is more likely than not the benefit will not be realized.
The Company had $40.1 million and $36.4 million of unrecognized tax benefits at June 30, 2024 and December 31, 2023, respectively. These amounts have been recorded as a reduction to the Company’s deferred tax asset, if recognized they would not have an impact on the effective tax rate due to the existing valuation allowance. Certain of the Company's unrecognized tax benefits could change due to activities of various tax authorities, including possible settlement of audits, or through normal expiration of various statutes of limitations. The Company does not expect a material change in unrecognized tax benefits in the next twelve months.
As of June 30, 2024, due to the carryforward of unutilized net operating losses and research and development credits, the Company is subject to U.S. federal income tax examinations for the tax years 2000 through 2024, and to state income tax examinations for the tax years 2000 through 2024. No interest or penalties related to income taxes have been accrued or recognized as of June 30, 2024.
The Organization for Economic Co-operation and Development has endorsed a framework (“Pillar Two”) with model rules introducing a global minimum corporate tax rate via a system where multinational groups with consolidated revenue over €750.0 million are subject to a minimum effective tax rate of 15% on income arising in low-tax jurisdictions on a country-by-country basis. Many countries have implemented laws based on these model rules, with effective dates beginning January 1, 2024. These rules do not have a material impact on the Company for the current period and, as currently designed, are not expected to materially increase the Company’s global tax costs. The Company will continue to monitor U.S. and global legislative action related to Pillar Two for potential impacts.

34
EXACT SCIENCES CORPORATION
Notes to Condensed Consolidated Financial Statements
(Unaudited)
(18) SUBSEQUENT EVENTS
On July 1, 2024, the Company entered into an exclusive license agreement with TwinStrand Biosciences, Inc. (“TwinStrand”), under which the Company will have the ability to use, commercialize, and sublicense the acquired intellectual property related to the cell free nucleic acid sequencing technology. Under the license agreement, the Company made upfront payments to TwinStrand totaling $45.0 million in July 2024. The license will be accounted for as an asset acquisition and the upfront consideration, which will be classified as an intangible asset in the condensed consolidated balance sheet, will be amortized through amortization of acquired intangible assets in the condensed consolidated statement of operations over its estimated useful life.
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Item 2. Management’s Discussion and Analysis of Financial Condition and Results of Operations
Objective
The purpose of this Management's Discussion and Analysis is to better allow our investors to understand and view our Company from management's perspective. We are providing an overview of our business and strategy including a discussion of our financial condition and results of operations. The following discussion of our financial condition and results of operations should be read in conjunction with the condensed consolidated financial statements and the related notes thereto included elsewhere in this Quarterly Report on Form 10-Q and the audited financial statements and notes thereto and Management’s Discussion and Analysis of Financial Condition and Results of Operations included in our Annual Report on Form 10-K for the year ended December 31, 2023, which has been filed with the U.S. Securities and Exchange Commission (“SEC”) (the “2023 Form 10-K”).

Forward-Looking Statements
This Quarterly Report on Form 10-Q contains forward-looking statements within the meaning of Section 27A of the Securities Act of 1933, as amended, and Section 21E of the Securities Exchange Act of 1934, as amended, that are intended to be covered by the “safe harbor” created by those sections. Forward-looking statements, which are based on certain assumptions and describe our future plans, strategies and expectations, can generally be identified by the use of forward-looking terms such as “believe,” “expect,” “may,” “will,” “should,” “would,” “could,” “seek,” “intend,” “plan,” “goal,” “project,” “estimate,” “anticipate” or other comparable terms. All statements other than statements of historical facts included in this Quarterly Report on Form 10-Q regarding our strategies, prospects, expectations, financial condition, operations, costs, plans and objectives are forward-looking statements. Examples of forward-looking statements include, among others, statements we make regarding expected future operating results; expectations for development of new or improved products and services and their impact on patients; our strategies, positioning, resources, capabilities and expectations for future events or performance; and the anticipated benefits of our acquisitions, including estimated synergies and other financial impacts. Forward-looking statements are neither historical facts nor assurances of future performance or events. Instead, they are based only on current beliefs, expectations and assumptions regarding the future of our business, future plans and strategies, projections, anticipated events and trends, the economy and other future conditions. Because forward-looking statements relate to the future, they are subject to inherent uncertainties, risks and changes in circumstances that are difficult to predict and many of which are outside of our control. Actual results, conditions and events may differ materially from those indicated in the forward-looking statements. Therefore, you should not rely on any of these forward-looking statements. Important factors that could cause actual results, conditions and events to differ materially from those indicated in the forward-looking statements include, among others, the following: our ability to successfully and profitably market our products and services; the acceptance of our products and services by patients and healthcare providers; our ability to meet demand for our products and services; our reliance upon certain suppliers, including suppliers that are the sole source of certain supplies and products used in our tests and operations; approval and maintenance of adequate reimbursement rates for our products and services within and outside of the U.S.; the amount and nature of competition for our products and services; the effects of any judicial, executive or legislative action affecting us or the healthcare system; recommendations, guidelines and quality metrics issued by various organizations regarding cancer screening or our products and services; our ability to successfully develop and commercialize new products and services and assess potential market opportunities; our ability to effectively enter into and utilize strategic partnerships and acquisitions; our success establishing and maintaining collaborative, licensing and supplier arrangements; our ability to obtain and maintain regulatory approvals and comply with applicable regulations; our ability to protect and enforce our intellectual property; the results of our validation studies and clinical trials, including the risks that the results of future studies and trials may differ materially from the results of previously completed studies and trials; our ability to manage an international business and our expectations regarding our international expansion and opportunities; our ability to raise the capital necessary to support our operations or meet our payment obligations under our indebtedness; the potential effects of changing macroeconomic conditions, including the effects of inflation, interest rate and foreign currency exchange rate fluctuations, and geopolitical conflict; the possibility that the anticipated benefits from our business acquisitions will not be realized in full or at all or may take longer to realize than expected; the possibility that costs or difficulties related to the integration of acquired businesses’ operations or the divestiture of business operations will be greater than expected and the possibility that integration or divestiture efforts will disrupt our business and strain management time and resources; the outcome of any litigation, government investigations, enforcement actions or other legal proceedings; and our ability to retain and hire key personnel. The risks included above are not exhaustive. Other important risks and uncertainties are described in the Risk Factors and in Management’s Discussion and Analysis of Financial Condition and Results of Operations sections of the 2023 Form 10-K and subsequently filed Quarterly Reports on Form 10-Q. You are further cautioned not to place undue reliance upon any such forward-looking statements, which speak only as of the date made. Except as otherwise required by the federal securities laws, we undertake no obligation to publicly update any forward-looking statement, whether written or oral, that may be made from time to time, whether as a result of new information, future developments or otherwise.
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Overview
A leading provider of cancer screening and diagnostic tests, Exact Sciences Corporation (together with its subsidiaries, “Exact,” “we,” “us,” “our” or the “Company”) gives patients and health care professionals the clarity needed to take life-changing action earlier. Building on the success of the Cologuard® and Oncotype DX® tests, we are investing in our pipeline to develop innovative solutions for use before, during, and after a cancer diagnosis.
During the second quarter of 2024, we achieved many critical milestones, including:
•being recognized as a Great Place to Work for the sixth consecutive year,
•screening over 1 million people in a quarter with our Cologuard test for the first time ever,
•testing a record number of cancer patients globally with Oncotype DX tests,
•generating revenue of $699.3 million for the three months ended June 30, 2024, an improvement of $77.2 million in comparison to three months ended June 30, 2023, while decreasing our loss from operations by $50.7 million,
•generating cash provided by operating activities of $107.1 million for the three months ended June 30, 2024, an improvement of $6.6 million in comparison to the three months ended June 30, 2023,
•securing an exclusive license to TwinStrand Bioscience Inc.’s (“TwinStrand”) patented technologies,
•making progress toward launching Cologuard PlusTM, our next-generation Cologuard test, and OncodetectTM, our molecular residual disease (“MRD”) test, and
•advancing several key pipeline programs, including blood-based colon cancer screening tests and our multi-cancer screening (“MCS”) test.

Our Screening Tests
Cologuard Test
Colorectal cancer is the second leading cause of cancer deaths in the United States (“U.S.”) and the leading cause of cancer deaths in the U.S. among non-smokers. Each year in the U.S., there are approximately 153,000 new cases of colorectal cancer and approximately 53,000 deaths. It is widely accepted that colorectal cancer is among the most preventable, yet least prevented cancers.
Our flagship screening product, the Cologuard test, is a patient-friendly, non-invasive stool-based DNA (“sDNA”) screening test that utilizes a multi-target approach to detect DNA and hemoglobin biomarkers associated with colorectal cancer and pre-cancer. Upon approval by the U.S. Food and Drug Administration (“FDA”) in August 2014, our Cologuard test became the first and only FDA-approved sDNA non-invasive colorectal cancer screening test. Our Cologuard test is now indicated for average risk adults 45 years of age and older.
Clinical Genetic Testing
We provide more than 5,000 predefined genetic tests for nearly all clinically relevant genes, additional custom panels, and comprehensive germline, whole exome (“PGxome®”), and whole genome (“PGnome®”) sequencing tests.
RiskguardTM, our hereditary cancer test, helps people understand their inherited risk of cancer, arming them with critical information to make more informed treatment decisions.

Our Precision Oncology Tests
Our precision oncology portfolio delivers actionable genomic insights to inform prognosis and cancer treatment after a diagnosis. In breast cancer, the Oncotype DX Breast Recurrence Score® test is the only test shown to predict the likelihood of chemotherapy benefit as well as the chance of cancer recurrence in the most common sub-type of early-stage breast cancer. As the only test proven to predict both the likelihood of chemotherapy benefit and cancer recurrence, the Oncotype DX test is recognized globally as standard of care and is included in all major breast cancer treatment guidelines. The OncoExTra® test applies comprehensive tumor profiling, utilizing whole exome and whole transcriptome sequencing, to aid in therapy selection for patients with advanced, metastatic, refractory, relapsed, or recurrent cancer. With an extensive panel of approximately 20,000 genes and 169 introns, the OncoExTra test is one of the most comprehensive genomic (DNA) and transcriptomic (RNA) panels available today. We enable patients to take a more active role in their cancer care and make it easy for providers to order tests, interpret results, and personalize medicine.
37

International Business Background and Products
We commercialize or plan to commercialize our Oncotype® tests internationally through employees in Canada, Japan and a number of European countries, as well as through exclusive distribution agreements. We have provided our Oncotype tests in approximately 120 countries outside of the U.S. We do not offer our Cologuard test outside of the U.S.

Pipeline Research and Development
Our research and development efforts are focused on developing new products and enhancing existing products to address unmet cancer needs and expand the clinical utility and addressable patient populations for our existing tests. We are focused on enhancing our Cologuard test’s performance characteristics and developing tissue, blood, and other sample type tests. These development efforts may lead to a variety of new products, including risk assessment, screening and prevention, early disease diagnosis, adjuvant and/or neoadjuvant disease treatment, metastatic disease treatment selection, and patient monitoring.
Through our collaboration with Mayo Foundation for Medical Education and Research (“Mayo”), we have successfully performed validation studies involving multiple types of cancer using tissue, blood, and other sample types. In September 2020, Mayo agreed to make available certain personnel to provide us research and development assistance through January 2025. Through recent business development activities, we have also acquired exclusive access to technologies developed by TwinStrand, The Johns Hopkins University, Broad Institute, Inc. (“Broad Institute”), Oxford University, and the Ludwig Institute for Cancer Research.
We are focusing our research and development efforts on three main areas:
•Colorectal Cancer Screening. Over the past decade, together with Mayo, we have been seeking to improve our Cologuard test’s performance characteristics, focusing on reducing the false positive rate of the test. In March 2024, the New England Journal of Medicine published our Cologuard Plus test results from the pivotal BLUE-C study, showing overall sensitivity of 94% for colorectal cancer at specificity of 91%, which is a 30% relative improvement compared to the false positive rate observed in our pivotal DeeP-C study for our Cologuard test. We submitted the final module of the Cologuard Plus test premarket approval application to the FDA in December 2023, and expect a decision in late 2024. We are also working to develop a blood-based screening test for colorectal cancer as a second-line option for people who haven't been screened with more accurate methods.
•MCS Test Development. We are currently seeking to develop a MCS test, which will be branded as CancerguardTM, to help detect many different types of cancer from a single blood draw. In September 2022, we presented data at the European Society for Medical Oncology (“ESMO”) Congress from a biomarker validation study, which demonstrated the ability to detect cancer signals from 15 organ sites with a mean sensitivity of 61% and mean specificity of 98.2%. The multi-biomarker approach detected stage I and stage II cancers with a combined sensitivity of 38.7%. In June 2023, we announced a collaboration with Baylor Scott & White to utilize our Cancerguard test within a subset of their clinics to generate real-world experience and evidence of our MCS screening approach. In April 2024, we presented late-breaking data at the American Association for Cancer Research (“AACR”) annual meeting from the first analysis of ASCEND-2, a multi-center, prospective, case-control study of over 11,000 clinically characterized participants. These results validate the sensitivity and specificity of our multi-biomarker class approach across a broad range of cancer types, including the most aggressive cancers and cancers with no current standard of care for screening. We plan to share additional analyses from ASCEND-2 at upcoming scientific conferences. Our MCS test was recently approved by the FDA to be used within a real-world evidence study, providing an opportunity to test 25,000 people over the next three years. In the future, we plan to begin recruiting patients for the FDA registrational Study of All comeRs (“SOAR”) trial, which we expect to be the largest prospective, interventional MCS trial ever conducted in the U.S.
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•MRD Test Development. We plan to offer our Oncodetect test, a tumor-informed MRD test to help detect small amounts of tumor DNA that may remain in patients’ blood after they have undergone initial cancer treatment. This test will help patients and oncologists understand the success of initial treatment, guide further treatment, and monitor for cancer recurrence. Our goal is to support all patients in MRD and recurrence monitoring, whether there is access to tumor tissue to inform patient-specific biomarker targets or no access to tissue and a predefined biomarker panel is used. We recently completed analytical validation of our tumor-informed platform utilizing colorectal cancer samples and are currently conducting a clinical validation study that will be submitted to MolDx for approval and subsequent Medicare reimbursement. In June 2023, we entered into a sponsored research agreement and exclusive license agreement with Broad Institute to utilize their Minor Allele Enriched Sequencing Through Recognition Oligonucleotides (“MAESTRO”) diagnostic testing technology to further our ability to develop and launch impactful MRD tests. We are developing the MAESTRO platform for use in certain future MRD tests.
Research and development, which includes our clinical study programs, accounts for a material portion of our operating expenses. As we seek to enhance our product portfolio and advance our pipeline, we expect that our research and development expenditures will continue to be a significant portion of our operating expenditures.

2024 Priorities
Our top priorities for 2024 are to (1) focus on our people and customers, (2) bring our portfolio to life, and (3) magnify our impact.
Focus on our People and Customers
We want to continue to provide an exceptional experience for our patients and team members. We plan to improve customer relations by delivering simple and smooth workflows, providing communication that is clear and easy to understand, and providing results that are fast and accurate. We will also strive to ensure that Exact Sciences remains a great place to work by taking care of our people.
Bring our Portfolio to Life
We will focus on advancing new tests in our highest priority programs including colorectal cancer screening, MRD, and multi-cancer screening. We plan to continue investing in our clinical trials to enhance existing products and bring new products to patients and providers, including obtaining FDA approval and securing coverage for our next generation Cologuard test, Cologuard Plus.
Magnify our Impact
We are committed to improving lives through testing more people with our laboratory testing services in 2024 including expanding screening access to underserved populations. By testing more people, we will continue to expand our business in a cost-efficient manner allowing us to generate sustainable profits and increase shareholder value. Generating sustained profits will put the company in a better position to continue investing in life-changing cancer diagnostics to help achieve our mission.
Recent Developments and Trends
We estimate there are up to 60 million Americans that are not up to date with their colon cancer screenings. The capacity for screening colonoscopies in the U.S. is relatively fixed because it is dependent on the number of gastroenterologists available to perform the procedures. Health systems and health care providers are motivated to increase screening rates because they are measured as part of the Healthcare Effectiveness Data and Information Set (“HEDIS”) and Medicare Stars quality measure systems. More health systems are recognizing the opportunity to partner with Exact Sciences to address their screening rates and related quality measures. We aim to partner with them to implement our Cologuard test as an essential part of their screening toolkit and embed it in their workflows. We continue to implement more electronic ordering interfaces connecting health systems to Exact Sciences. Our Cologuard test market share is increasing in larger health systems, helping us screen more Americans.
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We have an opportunity to impact even more lives by increasing adoption of Oncotype DX tests internationally. In 2023, we secured reimbursement for the Oncotype DX test in Japan. Breast cancer is the most common cancer among Japanese women, with about 45,000 new diagnoses of early-stage HR+, HER2- breast cancer each year. With reimbursement in place, we estimate our Oncotype DX test could help more than 100 women per day understand if their cancer is likely to recur and whether chemotherapy should be used in their treatment plan.

Results of Operations
We have incurred losses since our inception and, as of June 30, 2024, we had an accumulated deficit of approximately $3.60 billion. While our operating results have continued to improve, we expect to incur net losses for the near future, and it is possible we may never become profitable or sustain profitability.
Revenue. Our Screening revenue primarily includes laboratory service revenue from our Cologuard and Prevention Genetics, LLC (“PreventionGenetics”) tests while our Precision Oncology revenue primarily includes laboratory service revenue from global Oncotype DX and therapy selection tests.
Three Months Ended June 30,
Amounts in millions20242023Change
Screening$531.6 $462.8 $68.8 
Precision Oncology167.7 157.2 10.5 
COVID-19 Testing— 2.1 (2.1)
Total$699.3 $622.1 $77.2 
Six Months Ended June 30,
Amounts in millions20242023Change
Screening$1,006.4 $906.0 $100.4 
Precision Oncology330.4 312.6 17.8 
COVID-19 Testing— 6.0 (6.0)
Total$1,336.8 $1,224.5 $112.2 
The increase in Screening revenue was mainly due to an increase in the number of completed Cologuard tests. The increase in completed Cologuard tests for the three and six months ended June 30, 2024 was due to growth across all customer segments, more patients rescreening with our Cologuard test, and expansion of organized screening programs run by payers and health systems. The increase in Precision Oncology revenue was mainly due to an increase in the number of completed Oncotype DX breast cancer tests, both domestically and internationally, led by an increased number of ordering providers outside the U.S., specifically in Japan. We discontinued our COVID-19 testing business in the second quarter of 2023 due to lower demand, which led to the decrease in COVID-19 testing revenue. A discussion on our COVID-19 testing business was provided in our Annual Report on Form 10-K for the year ended December 31, 2023.
Adjustments to revenue recognized during the period relating to prior period estimates were less than 1% of revenue recorded in our condensed consolidated statement of operations for the three and six months ended June 30, 2024. Adjustments to revenue recognized during the period relating to prior period estimates were less than 2% of revenue recorded in our condensed consolidated statement of operations for the three and six months ended June 30, 2023. The impact to revenue for the three and six months ended June 30, 2023 was due to improvements made in our billing systems and processes, including international contracting and collections.
We expect continuing revenue growth for our Cologuard and Oncotype tests subject to seasonal variability. Our revenues are affected by the test volume of our products, patient adherence rates, payer mix, the levels of reimbursement, our order to cash operations, and payment patterns of payers and patients.
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Cost of sales (exclusive of amortization of acquired intangible assets). The increase in cost of sales for the three and six months ended June 30, 2024 was primarily due to an increase in production costs, personnel expenses, and facility and support services, which was a result of an increase in completed Cologuard and Oncotype tests and the corresponding increase in headcount to support the increase in tests completed. Cost of sales (exclusive of amortization of acquired intangible assets) as a percentage of revenue was consistent for the three and six months ended June 30, 2024 and June 30, 2023. We expect that cost of sales will generally continue to increase in future periods as a result of an increase in our existing laboratory testing services and as we launch our pipeline products. We also expect to see a corresponding increase in personnel and support services associated with this growth.
Three Months Ended June 30,
Amounts in millions20242023Change
Production costs$117.9 $93.9 $24.0 
Personnel expenses47.9 43.5 4.4 
Facility and support services17.5 13.1 4.4 
Stock-based compensation5.7 5.5 0.2 
Other cost of sales expenses0.8 1.0 (0.2)
Total cost of sales expense$189.8 $157.0 $32.8 
Six Months Ended June 30,
Amounts in millions20242023Change
Production costs$216.0 $186.6 $29.4 
Personnel expenses98.1 88.6 9.5 
Facility and support services33.1 26.6 6.5 
Stock-based compensation10.9 10.3 0.6 
Other cost of sales expenses1.8 1.8 — 
Total cost of sales expense$359.9 $313.9 $46.0 
Research and development expenses. The increase in research and development expenses for the three and six months ended June 30, 2024 was primarily due to the termination of a license agreement with The Translational Genomics Research Institute (“TGen”) resulting in the recognition of an expense of $25.8 million in the second quarter of 2024. In addition, personnel expenses grew for the three and six months ended June 30, 2024 due to an increase in headcount. Our direct research and development costs primarily relate to research related expenses for the development of MRD and MCS tests and our colorectal cancer screening test pipeline. The decrease in direct research and development costs for the three and six months ended June 30, 2024 was primarily due to a reduction in BLUE-C related costs as the study was completed in 2023, which was partially offset by an increase in MRD related research activities. We expect that research and development expenses will generally continue to increase in future periods as we continue to invest to advance new tests.
Three Months Ended June 30,
Amounts in millions20242023Change
Personnel expenses$44.3 $41.9 $2.4 
License agreement termination25.8 — 25.8 
Direct research and development23.0 33.9 (10.9)
Facility and support services14.5 14.9 (0.4)
Stock-based compensation9.9 10.7 (0.8)
Professional fees2.8 1.7 1.1 
Other research and development0.6 1.0 (0.4)
Total research and development expenses$120.9 $104.1 $16.8 
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Six Months Ended June 30,
Amounts in millions20242023Change
Personnel expenses$97.3 $85.6 $11.7 
Direct research and development52.8 59.5 (6.7)
Facility and support services28.6 29.5 (0.9)
License agreement termination25.8 — 25.8 
Stock-based compensation21.7 20.5 1.2 
Professional fees4.6 3.1 1.5 
Other research and development0.7 1.3 (0.6)
Total research and development expenses$231.5 $199.5 $32.0 
Sales and marketing expenses. Sales and marketing expenses increased for the three and six months ended June 30, 2024 compared to the three and six months ended June 30, 2023 due to continued investment in high impact sales and marketing opportunities. We anticipate sales and marketing expenses will generally increase in future periods as we reinvest in sales and marketing to meet demand for current products and the launch of new products, while continuing to decrease as a percentage of revenue over time, driven by the growth of Cologuard and Oncotype testing services.
Three Months Ended June 30,
Amounts in millions20242023Change
Personnel expenses$106.4 $100.8 $5.6 
Direct marketing costs48.7 44.7 4.0 
Stock-based compensation13.7 18.6 (4.9)
Professional and legal fees13.4 7.6 5.8 
Facility and support services2.7 4.0 (1.3)
Other sales and marketing expenses0.4 0.8 (0.4)
Total sales and marketing expenses$185.3 $176.5 $8.8 
Six Months Ended June 30,
Amounts in millions20242023Change
Personnel expenses$216.3 $211.1 $5.2 
Direct marketing costs 96.0 91.9 4.1 
Stock-based compensation30.3 31.4 (1.1)
Professional and legal fees28.9 18.6 10.3 
Facility and support services5.5 8.6 (3.1)
Other sales and marketing expenses0.6 1.9 (1.3)
Total sales and marketing expenses$377.6 $363.5 $14.1 
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General and administrative expenses. The decrease in general and administrative expenses for the three and six months ended June 30, 2024 was primarily due to a reduction in professional and legal fees for the three and six months ended June 30, 2024 from the settlement of certain legal matters in 2023, as further described in Note 15 of our Annual Report on Form 10-K for the year ended December 31, 2023. The decrease in other general and administrative expenses was primarily due to gains of $13.2 million and $7.6 million for the three and six months ended June 30, 2024, respectively, compared to an expense of $4.2 million and a gain of $4.7 million for the three and six months ended June 30, 2023, respectively, as a result of the change in fair value of our outstanding contingent consideration liabilities as further described in Note 7 of our condensed consolidated financial statements included in this Quarterly Report on Form 10-Q. The decrease in general and administrative expenses for the three and six months ended June 30, 2024 was partially offset by an increase in personnel expenses. This increase was a result of additional headcount to support the growth of our operations. We expect general and administrative expenses throughout the remainder of 2024 will remain relatively consistent with costs incurred in the first half of 2024. We expect general and administrative expenses will decrease over time as we leverage efficiencies in our personnel and information technology systems.
Three Months Ended June 30,
Amounts in millions20242023Change
Personnel expenses$100.0 $94.3 $5.7 
Facility and support services44.1 44.5 (0.4)
Professional and legal fees29.9 54.6 (24.7)
Stock-based compensation27.3 26.9 0.4 
Other general and administrative0.6 17.7 (17.1)
Total general and administrative expenses$201.9 $238.0 $(36.1)
Six Months Ended June 30,
Amounts in millions20242023Change
Personnel expenses$214.1 $192.7 $21.4 
Facility and support services89.2 87.3 1.9 
Professional and legal fees67.3 101.6 (34.3)
Stock-based compensation54.0 48.7 5.3 
Other general and administrative20.4 25.0 (4.6)
Total general and administrative expenses$445.0 $455.3 $(10.3)
Amortization of acquired intangible assets. Amortization of acquired intangible assets increased to $23.3 million for the three months ended June 30, 2024 compared to $22.9 million for the three months ended June 30, 2023. Amortization of acquired intangible assets increased to $46.6 million for the six months ended June 30, 2024 compared to $45.9 million for the six months ended June 30, 2023. The increase was primarily due to amortization of the intangible asset acquired as part of our acquisition of Resolution Bioscience in September 2023.
Impairment of long-lived assets. Impairment of long-lived assets was $8.2 million and $12.6 million for the three and six months ended June 30, 2024, respectively, compared to $0.6 million for the three and six months ended June 30, 2023. The impairment charges recorded during the three and six months ended June 30, 2024 and 2023 related to certain of our domestic facilities.
Other operating income. Other operating income was $3.8 million and $3.5 million for the three and six months ended June 30, 2024 compared to zero for the three and six months ended June 30, 2023. The income recorded for the three and six months ended June 30, 2024 represents the remeasurement of the contingent consideration asset from the sale of the Oncotype DX Genomic Prostate Score test to MDxHealth SA.
Investment income, net. Investment income, net increased to $11.8 million for the three months ended June 30, 2024 compared to $4.8 million for the three months ended June 30, 2023. Investment income, net increased to $18.0 million for the six months ended June 30, 2024 compared to $5.3 million for the six months ended June 30, 2023. The investment income recorded for the three and six months ended June 30, 2024 and 2023 was primarily due to gains recorded on our marketable securities.
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Interest income (expense), net. Net interest income was $0.1 million for the three months ended June 30, 2024 compared to interest expense of $7.8 million for the three months ended June 30, 2023. Interest expense recorded from our outstanding convertible notes totaled $8.4 million and $6.2 million for the three months ended June 30, 2024 and 2023, respectively. Interest expense increased to $7.8 million for the six months ended June 30, 2024 compared to $3.7 million for the six months ended June 30, 2023. Interest expense recorded from our outstanding convertible notes totaled $14.7 million and $11.0 million for the six months ended June 30, 2024 and 2023, respectively. Interest income (expense), net for the three and six months ended June 30, 2024 included a net gain on settlement of convertible notes of $10.3 million. Interest income (expense), net for the six months ended June 30, 2023 included a net gain on settlement of convertible notes of $10.3 million. The convertible notes are further described in Note 9 of our condensed consolidated financial statements included in this Quarterly Report on Form 10-Q.
Income tax expense. Income tax expense increased to $1.5 million for the three months ended June 30, 2024 compared to $1.1 million for the three months ended June 30, 2023. Income tax expense increased to $3.3 million for the six months ended June 30, 2024 compared to $2.8 million for the six months ended June 30, 2023. Income tax expense for the three and six months ended June 30, 2024 and 2023 was primarily related to current foreign and state tax expense.
Liquidity and Capital Resources
Overview
We have incurred losses since our inception, and have historically financed our operations primarily through public offerings of our common stock and convertible debt and through revenue generated by the sale of our laboratory testing services. We expect our operating expenditures to continue to increase to support future growth of our laboratory testing services, as well as an increase in research and development and clinical trial costs to support the advancement of our pipeline products and bringing new tests to market. We expect that cash, cash equivalents and marketable securities on hand at June 30, 2024, along with cash flows generated through our operations, will be sufficient to fund our current operations for at least the next twelve months based on current operating plans.
We have access to a revolving line-of-credit (the “Revolver”) of up to $150.0 million, which had its maturity date extended to November 2025 through an amended agreement in October 2022. The Revolver is collateralized by certain marketable securities which must continue to maintain a minimum market value of $150.0 million. PNC Bank, National Association has issued letters of credit totaling $4.4 million, which reduces the amount available for cash advances under the line of credit to $145.6 million. As of June 30, 2024, we had not drawn any funds under the Revolver. The Revolver is further described in Note 8 of our condensed consolidated financial statements included in this Quarterly Report on Form 10-Q.
We may raise additional capital to expand our business, to pursue strategic investments, to take advantage of financing opportunities or for other reasons. If we are unable to obtain sufficient additional funds to enable us to fund our business plans and strategic investments, our results of operations and financial condition could be materially adversely affected, and we may be required to delay the implementation of our plans or otherwise scale back our operations. There can be no certainty that we will ever be successful in generating sufficient cash flow from operations to achieve and maintain profitability and meet all of our obligations as they come due.
Cash, Cash Equivalents and Marketable Securities
As of June 30, 2024, we had approximately $530.2 million in unrestricted cash and cash equivalents and approximately $416.6 million in marketable securities.
The majority of our investments in marketable securities consist of fixed income investments, and all are deemed available-for-sale. The objectives of this portfolio are to provide liquidity and safety of principal while striving to achieve the highest rate of return. Our investment policy limits investments to certain types of instruments issued by institutions with investment grade credit ratings and places restrictions on maturities and concentration by type and issuer.
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Cash Flows
Six Months Ended June 30,
Amounts In millions20242023
Net cash provided by operating activities$24.8 $62.2 
Net cash provided by (used in) investing activities(318.6)149.4 
Net cash provided by financing activities221.6 149.6 
Operating activities
The decrease in cash provided by operating activities for the six months ended June 30, 2024 was primarily due to an increase in operating expenses and cost of sales to support the increase in revenue as discussed in the Results of Operations section above and timing on payments on our accounts payable and accrued expenses and collections of our accounts receivable This was partially offset by an increase in revenue as a result of an increase in the number of completed Cologuard and Oncotype tests, which was the primary driver of the decrease in our net loss.
Investing activities
The increase in cash used in investing activities for the six months ended June 30, 2024 compared to cash provided by investing activities for the six months ended June 30, 2023 was due to a net increase of $464.2 million in cash used for purchases, maturities and sales of marketable securities as a result of a change in investing strategy towards more fixed income securities compared to money market funds as money market yields have decreased. We also increased our purchases of property, plant and equipment by $9.4 million due to additional investments in information technology infrastructure and lab automation.
Financing activities
The increase in cash provided by financing activities during the six months ended June 30, 2024 compared to the six months ended June 30, 2023 was primarily due to proceeds of $266.8 million from the issuance of convertible notes in the second quarter of 2024 compared to proceeds of $138.0 million from the issuance of convertible notes in the first quarter of 2023. This was partially offset by a payment of $50.0 million in settlement of our previously outstanding accounts receivable securitization facility (“Securitization Facility”) upon maturity in June 2024.
Material Cash Requirements
A discussion of our material cash requirements as of December 31, 2023 was provided in the Management’s Discussion and Analysis of Financial Condition and Results of Operation of our 2023 Form 10-K. Other than the matters described below, there were no material changes outside the ordinary course of our business in our specified material cash requirements during the six months ended June 30, 2024.
In April 2024, we entered into privately negotiated agreements (the “Agreements”) with certain holders of our 2028 Notes. Pursuant to the Agreements, we issued $620.7 million aggregate principal amount of a new series of Convertible Notes due in 2031 (the “2031 Notes”) in exchange for (i) the retirement of $359.7 million in aggregate principal amount of 2028 Notes, and (ii) payment to the Company of $266.8 million in cash. The net proceeds from the issuance of the Notes were approximately $259.8 million, after deducting commissions and the offering expenses payable by the Company. The 2031 Notes mature on April 15, 2031 and bear interest at a fixed rate of 1.75% per year, payable semiannually in arrears on October 15 and April 15 of each year, beginning on October 15, 2024.
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As of June 30, 2024, we had outstanding aggregate principal of $249.2 million on our convertible notes with a maturity date of January 15, 2025 (the “2025 Notes”), which are classified as convertible notes, net, current portion on the condensed consolidated balance sheet. Beginning six months prior to the maturity date on July 15, 2024, holders of the 2025 Notes may convert such notes at any time. In accordance with the terms of the 2025 Notes, any 2025 Notes that are converted after July 15, 2024 will be settled through a combination settlement under which the par value will be settled in cash and any amount in excess of par value will be settled in shares of our common stock. 2025 Notes that are not converted prior to the maturity date will be settled in cash upon maturity.
In June 2024, we repaid the previously outstanding balance of $50.0 million in full upon maturity of the Securitization Facility. Prior to maturity, the Securitization Facility accrued interest at a rate equal to a daily secured overnight financing rate (“SOFR”) plus a SOFR adjustment and an applicable margin. The interest rate was 6.87% as of the maturity date.
As of June 30, 2024, we had no off-balance sheet arrangements.

Critical Accounting Policies and Estimates
Management’s discussion and analysis of our financial condition and results of operations is based on our condensed consolidated financial statements, which have been prepared in accordance with accounting principles generally accepted in the U.S. The preparation of these financial statements requires us to make estimates and assumptions that affect the amounts reported in our condensed consolidated financial statements and accompanying notes. On an ongoing basis, we evaluate our estimates and judgments. We base our estimates on historical experience and on various other factors that are believed to be appropriate under the circumstances, the results of which form the basis for making judgments about the carrying value of assets and liabilities that are not readily apparent from other sources. Actual results may differ from these estimates under different assumptions or conditions.
For a discussion of our critical accounting policies and estimates, refer to our Management’s Discussion and Analysis of Financial Condition and Results of Operations in our 2023 Form 10-K. There have been no material changes to our critical accounting policies and estimates since our 2023 Form 10-K.
Recent Accounting Pronouncements
See Note 1 of our condensed consolidated financial statements for the discussion of Recent Accounting Pronouncements.

Item 3. Quantitative and Qualitative Disclosures About Market Risk
Interest Rate Risk
Our exposure to market risk is principally confined to our cash, cash equivalents and marketable securities and our outstanding variable-rate debt. We invest our cash, cash equivalents, and marketable securities in securities of the U.S. governments and its agencies and in investment-grade, highly liquid investments consisting of commercial paper, bank certificates of deposit, and corporate bonds, which as of June 30, 2024 and December 31, 2023 were classified as available-for-sale. We place our cash, cash equivalents, restricted cash, and marketable securities with high-quality financial institutions, limit the amount of credit exposure to any one institution, and have established investment guidelines relative to diversification and maturities designed to maintain safety and liquidity.
Based on a hypothetical 100 basis point decrease in market interest rates, the potential losses in future earnings, fair value of risk-sensitive financial instruments, and cash flows are immaterial, although the actual effects may differ materially from the hypothetical analysis. While we believe our cash, cash equivalents, restricted cash, and marketable securities do not contain excessive risk, we cannot provide absolute assurance that, in the future, our investments will not be subject to adverse changes in market value. In addition, we maintain significant amounts of cash, cash equivalents, restricted cash, and marketable securities at one or more financial institutions that are in excess of federally insured limits. Given the potential instability of financial institutions, we cannot provide assurance that we will not experience losses on these deposits. We do not utilize interest rate hedging agreements or other interest rate derivative instruments.
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As of June 30, 2024, we had no outstanding variable rate debt. If we were to draw down amounts under our Revolving Loan, we would be impacted by increases in prevailing market interest rates. All of our other significant interest-bearing liabilities bear interest at fixed rates and therefore are not subject to fluctuations in market interest rates; however, because these interest rates are fixed, we may be paying a higher interest rate, relative to market, in the future if circumstances change.
Foreign Currency Risk
The functional currency for most of our international subsidiaries is the U.S. dollar, and as a result we are not subject to material gains and losses from foreign currency translation of the subsidiary financial statements. Substantially all of our revenues are recognized in U.S. dollars, although a small portion is denominated in foreign currency as we continue to expand into markets outside of the U.S. Certain expenses related to our international activities are payable in foreign currencies. As a result, factors such as changes in foreign currency exchange rates or weak economic conditions in foreign markets will affect our financial results.
We enter into forward contracts to mitigate the impact of adverse movements in foreign exchange rates related to the re-measurement of monetary assets and liabilities and hedge our foreign currency exchange rate exposure. As of June 30, 2024, we had open foreign currency forward contracts with notional amounts of $45.2 million. Although the impact of currency fluctuations on our financial results has been immaterial in the past, there can be no guarantee that the impact of currency fluctuations related to our international activities will not be material in the future.

Item 4. Controls and Procedures
As of the end of the period covered by this report, we carried out an evaluation, under the supervision and with the participation of our management, including our principal executive officer and our principal financial officer, of the effectiveness of our disclosure controls and procedures, as defined in Rule 13a-15(e) promulgated under the Securities Exchange Act of 1934, as amended (the “Exchange Act”). Based upon that evaluation, our principal executive officer and our principal financial officer concluded that, as of June 30, 2024, our disclosure controls and procedures were effective. Disclosure controls and procedures enable us to record, process, summarize and report information required to be included in our Exchange Act filings within the required time period. Our disclosure controls and procedures include controls and procedures designed to ensure that information required to be disclosed by us in the periodic reports filed with the SEC is accumulated and communicated to our management, including our principal executive, financial and accounting officers, or persons performing similar functions, as appropriate to allow timely decisions regarding required disclosure.
In the second quarter of 2024, we completed the implementation of Epic Systems’ electronic medical records software in our clinical laboratory systems for certain of our precision oncology tests in the United States. Epic Systems’ software has been used for our Cologuard test since 2019. We have updated our internal controls, as applicable, to facilitate modifications to our business processes and accounting procedures and will continue to evaluate the operating effectiveness of related key controls during subsequent periods. We do not believe that the Epic Systems implementation has had an adverse effect on our internal control over financial reporting.
There have been no other significant changes in internal control over financial reporting during the quarter ended June 30, 2024 that have materially affected, or are reasonably likely to materially affect, our internal control over financial reporting.
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Part II - Other Information

Item 1. Legal Proceedings
From time to time we are a party to various legal proceedings arising in the ordinary course of our business. Legal proceedings, including litigation, government investigations and enforcement actions could result in material costs, occupy significant management resources and entail civil and criminal penalties. The information called for by this item is incorporated by reference to the information in Note 13 of our condensed consolidated financial statements included in Part I of this Quarterly Report on Form 10-Q.

Item 1A. Risk Factors
We operate in a rapidly changing environment that involves a number of risks that could materially affect our business, financial condition or future results, some of which are beyond our control. In addition to the other information set forth in this report, the risks and uncertainties that we believe are most important for you to consider are discussed in Part I, “Item 1A. Risk Factors” in the 2023 Form 10-K and in Part II, “Item 1A. Risk Factors” in our subsequently filed Quarterly Reports on Form 10-Q. There have been no material changes to the risk factors described in the 2023 Form 10-K and subsequently filed Quarterly Report on Form 10-Q.
Item 2. Unregistered Sales of Equity Securities and Use of Proceeds
Not applicable.

Item 3. Defaults Upon Senior Securities
Not applicable.

Item 4. Mine Safety Disclosures
Not applicable.

Item 5. Other Information
Rule 10b5-1 Trading Plans
During the fiscal quarter ended June 30, 2024, none of our directors or officers (as defined in Rule 16a-1 under the Exchange Act) adopted or terminated a “Rule 10b5-1 trading arrangement” or “non-Rule 10b5-1 trading arrangement” (as those terms are defined in Item 408 of Regulation S-K), except as follows:
On May 13, 2024, Brian Baranick, Executive Vice President and General Manager, Precision Oncology, adopted a Rule 10b5-1 trading arrangement for the sale of up to $200,000 in shares of our common stock. The arrangement’s expiration date is December 31, 2025, subject to early termination for certain specified events set forth in the arrangement.
On June 4, 2024, James Doyle, a member of our board of directors, terminated a Rule 10b5-1 trading arrangement. The terminated Rule 10b5-1 trading arrangement was originally adopted on November 13, 2023 and provided for the sale of up to 4,900 shares of our common stock.
Departure of Former Chief Financial Officer
As previously disclosed, Jeffrey Elliott, our former Chief Financial Officer, assumed the role as special advisor to the Chief Executive Officer effective May 15, 2024 to facilitate a smooth transition in connection with Aaron Bloomer’s appointment as our new Chief Financial Officer. Following a successful transition, Mr. Elliott’s employment with the Company will terminate on August 2, 2024.
48
2010 Employee Stock Purchase Plan Amendments
Effective July 31, 2024, the Company’s 2010 Employee Stock Purchase Plan was amended to (1) shorten the length of future offering periods under the plan from twenty-four to six months and (2) make certain other clarifying changes.
Employment Agreement Amendments
At its meeting held on July 25, 2024, based upon a review of severance benefits contained in the employment agreements of the Company’s executive officers compared to the Company’s compensation peer group, the Company’s Human Capital Committee approved the modifications described below for each of Brian Baranick, Aaron Bloomer, Sarah Condella and Jake Orville.
Specifically, the Human Capital Committee approved modifications to each individual’s employment agreement with the Company to provide that, if within four months before or twelve months after a Company “change in control,” the individual incurs a termination of employment initiated by the Company without “cause” or by the individual for “good reason” (each such quoted term as defined in the applicable employment agreement), the individual will receive a cash severance benefit equal to 18 months base salary, pro-rata target annual bonus for the year of termination, 150% of the individual’s target annual bonus, up to 12 months of COBRA premiums, and $10,000 for outplacement services.
The foregoing severance benefits are subject to the individual executing and not revoking a waiver and release of claims in favor of the Company and its affiliates.
49
Item 6. Exhibits
The following documents are filed as part of this Form 10-Q.
Exhibit
Number		Exhibit DescriptionFiled
with
This
Report		Incorporated
by Reference
herein from
Form or
Schedule		Filing
Date		SEC File /
Registration
Number
Sixth Amended and Restated Certificate of Incorporation of the RegistrantS-1 (Exhibit 3.3)12/4/2000333-48812
Certificate of Amendment, dated July 23, 2020, to the Sixth Amended and Restated Certificate of Incorporation of the Registrant8-K (Exhibit 3.1)7/24/2020001-35092
Certificate of Amendment, dated June 9, 2023, to the Sixth Amended and Restated Certificate of Incorporation of the Registrant8-K (Exhibit 3.1)6/12/2023001-35092
Seventh Amended and Restated By-Laws of the Registrant8-K (Exhibit 3.2)6/12/2023001-35092
Fifth Supplemental Indenture, dated April 17, 2024, between the Company and U.S. Bank National Association, as Trustee (including the form of 1.75% Convertible Senior Notes due 2031).
8-K
(Exhibit 4.2)
4/17/2024
001-35092
Employment Agreement, dated April 15, 2024, by and between Aaron Bloomer and the Registrant
10-Q
(Exhibit 10.1)
5/8/2024
001-35092
Certification Pursuant to Rule 13(a)-14(a) or Rule 15d-14(a) of Securities Exchange Act of 1934X
Certification Pursuant to Rule 13(a)-14(a) or Rule 15d-14(a) of Securities Exchange Act of 1934X
Certification Pursuant to 18 U.S.C. Section 1350, as Adopted Pursuant to Section 906 of the Sarbanes-Oxley Act of 2002X
101
The following materials from the Quarterly Report on Form 10-Q of Exact Sciences Corporation for the quarter ended June 30, 2024 filed on July 31, 2024, formatted in Inline eXtensible Business Reporting Language (“iXBRL”): (i) Condensed Consolidated Balance Sheets, (ii) Condensed Consolidated Statements of Operations, (iii) Condensed Consolidated Statement of Changes in Stockholders’ Equity, (iv) Condensed Consolidated Statements of Cash Flows and (v) related notes to these financial statements
X
104
The cover page from our Quarterly Report for the period ended June 30, 2024, filed with the Securities and Exchange Commission on July 31, 2024, is formatted in Inline Extensible Business Reporting Language (“iXBRL”)
X


50
SIGNATURES
Pursuant to the requirements of the Securities Exchange Act of 1934, the Registrant has duly caused this report to be signed on its behalf by the undersigned thereunto duly authorized.
EXACT SCIENCES CORPORATION
Date: July 31, 2024
By:/s/ Kevin T. Conroy
Kevin T. Conroy
President and Chief Executive Officer
(Principal Executive Officer)
Date: July 31, 2024
By:
/s/ Aaron Bloomer
Aaron Bloomer
Executive Vice President and Chief Financial Officer
(Principal Financial and Accounting Officer)

51
EXHIBIT 31.1
Certification pursuant to Section 302 of the Sarbanes-Oxley Act of 2002
I, Kevin T. Conroy, certify that:
1.I have reviewed this quarterly report on Form 10-Q of Exact Sciences Corporation (the “registrant”);
2.Based on my knowledge, this report does not contain any untrue statement of a material fact or omit to state a material fact necessary to make the statements made, in light of the circumstances under which such statements were made, not misleading with respect to the period covered by this report;
3.Based on my knowledge, the financial statements, and other financial information included in this report, fairly present in all material respects the financial condition, results of operations and cash flows of the registrant as of, and for, the periods presented in this report;
4.The registrant’s other certifying officer and I are responsible for establishing and maintaining disclosure controls and procedures (as defined in Exchange Act Rules 13a-15(e) and 15d-15(e)) and internal control over financial reporting (as defined in Exchange Act Rules 13a-15(f) and 15d-15(f)) for the registrant and have:
a)Designed such disclosure controls and procedures, or caused such disclosure controls and procedures to be designed under our supervision, to ensure that material information relating to the registrant, including its consolidated subsidiaries, is made known to us by others within those entities, particularly during the period in which this report is being prepared;
b)Designed such internal control over financial reporting, or caused such internal control over financial reporting to be designed under our supervision, to provide reasonable assurance regarding the reliability of financial reporting and the preparation of financial statements for external purposes in accordance with generally accepted accounting principles;
c)Evaluated the effectiveness of the registrant’s disclosure controls and procedures and presented in this report our conclusions about the effectiveness of the disclosure controls and procedures, as of the end of the period covered by this report based on such evaluation; and
d)Disclosed in this report any change in the registrant’s internal control over financial reporting that occurred during the registrant’s most recent fiscal quarter (the registrant’s fourth fiscal quarter in the case of an annual report) that has materially affected, or is reasonably likely to materially affect, the registrant’s internal control over financial reporting; and
5.The registrant’s other certifying officer and I have disclosed, based on our most recent evaluation of internal control over financial reporting, to the registrant’s auditors and the audit committee of the registrant’s board of directors (or persons performing the equivalent functions):
a)All significant deficiencies and material weaknesses in the design or operation of internal control over financial reporting which are reasonably likely to adversely affect the registrant’s ability to record, process, summarize and report financial information; and
b)Any fraud, whether or not material, that involves management or other employees who have a significant role in the registrant’s internal control over financial reporting.
Date: July 31, 2024
By:/s/ Kevin T. Conroy
Kevin T. Conroy
President and Chief Executive Officer
(Principal Executive Officer)

EXHIBIT 31.2
Certification pursuant to Section 302 of the Sarbanes-Oxley Act of 2002
I, Aaron Bloomer, certify that:
1.I have reviewed this quarterly report on Form 10-Q of Exact Sciences Corporation (the “registrant”);
2.Based on my knowledge, this report does not contain any untrue statement of a material fact or omit to state a material fact necessary to make the statements made, in light of the circumstances under which such statements were made, not misleading with respect to the period covered by this report;
3.Based on my knowledge, the financial statements, and other financial information included in this report, fairly present in all material respects the financial condition, results of operations and cash flows of the registrant as of, and for, the periods presented in this report;
4.The registrant’s other certifying officer and I are responsible for establishing and maintaining disclosure controls and procedures (as defined in Exchange Act Rules 13a-15(e) and 15d-15(e)) and internal control over financial reporting (as defined in Exchange Act Rules 13a-15(f) and 15d-15(f)) for the registrant and have:
a)Designed such disclosure controls and procedures, or caused such disclosure controls and procedures to be designed under our supervision, to ensure that material information relating to the registrant, including its consolidated subsidiaries, is made known to us by others within those entities, particularly during the period in which this report is being prepared;
b)Designed such internal control over financial reporting, or caused such internal control over financial reporting to be designed under our supervision, to provide reasonable assurance regarding the reliability of financial reporting and the preparation of financial statements for external purposes in accordance with generally accepted accounting principles;
c)Evaluated the effectiveness of the registrant’s disclosure controls and procedures and presented in this report our conclusions about the effectiveness of the disclosure controls and procedures, as of the end of the period covered by this report based on such evaluation; and
d)Disclosed in this report any change in the registrant’s internal control over financial reporting that occurred during the registrant’s most recent fiscal quarter (the registrant’s fourth fiscal quarter in the case of an annual report) that has materially affected, or is reasonably likely to materially affect, the registrant’s internal control over financial reporting; and
5.The registrant’s other certifying officer and I have disclosed, based on our most recent evaluation of internal control over financial reporting, to the registrant’s auditors and the audit committee of the registrant’s board of directors (or persons performing the equivalent functions):
a)All significant deficiencies and material weaknesses in the design or operation of internal control over financial reporting which are reasonably likely to adversely affect the registrant’s ability to record, process, summarize and report financial information; and
b)Any fraud, whether or not material, that involves management or other employees who have a significant role in the registrant’s internal control over financial reporting.
Date: July 31, 2024
By:/s/ Aaron Bloomer
Aaron Bloomer
Executive Vice President and Chief Financial Officer
(Principal Financial and Accounting Officer)

EXHIBIT 32.1
CERTIFICATION PURSUANT TO
18 U.S.C. SECTION 1350
AS ADOPTED PURSUANT TO
SECTION 906 OF THE SARBANES-OXLEY ACT OF 2002 
In connection with the Quarterly Report of Exact Sciences Corporation (the “Company”) on Form 10-Q for the quarter ended June 30, 2024 as filed with the Securities and Exchange Commission on the date hereof (the “Report”), we, Kevin T. Conroy, President and Chief Executive Officer of the Company and Aaron Bloomer, Chief Financial Officer of the Company, certify, pursuant to 18 U.S.C. Section 1350, as adopted pursuant to Section 906 of the Sarbanes-Oxley Act of 2002, to our knowledge, that:
(1)The Report fully complies with the requirements of Section 13(a) or 15(d) of the Securities Exchange Act of 1934; and
(2)The information contained in the Report fairly presents, in all material respects, the financial condition and results of operations of the Company. 
Dated: July 31, 2024
/s/ Kevin T. Conroy
Name:Kevin T. Conroy
Title:President and Chief Executive Officer
(Principal Executive Officer)
Dated: July 31, 2024
/s/ Aaron Bloomer
Name:Aaron Bloomer
Title:Executive Vice President and Chief Financial Officer
(Principal Financial Officer and Principal Accounting Officer)


v3.24.2
Cover Page - shares
 6 Months Ended
Jun. 30, 2024
Jul. 30, 2024
Cover [Abstract]    
Document Type 10-Q  
Document Quarterly Report true  
Document Period End Date Jun. 30, 2024  
Document Transition Report false  
Entity File Number 001-35092  
Entity Registrant Name EXACT SCIENCES CORPORATION  
Entity Incorporation, State or Country Code DE  
Entity Tax Identification Number 02-0478229  
Entity Address, Address Line One 5505 Endeavor Lane  
Entity Address, City or Town Madison  
Entity Address, State or Province WI  
Entity Address, Postal Zip Code 53719  
City Area Code 608  
Local Phone Number 535-8815  
Title of 12(b) Security Common Stock, $0.01 par value per share  
Trading Symbol EXAS  
Security Exchange Name NASDAQ  
Entity Current Reporting Status Yes  
Entity Interactive Data Current Yes  
Entity Filer Category Large Accelerated Filer  
Entity Small Business false  
Entity Emerging Growth Company false  
Entity Shell Company false  
Entity Common Stock, Shares Outstanding   184,769,862
Document Fiscal Year Focus 2024  
Document Fiscal Period Focus Q2  
Entity Central Index Key 0001124140  
Amendment Flag false  
Current Fiscal Year End Date --12-31  
v3.24.2
Condensed Consolidated Balance Sheets - USD ($)
$ in Thousands
Jun. 30, 2024
Dec. 31, 2023
Current assets:    
Cash and cash equivalents $ 530,180 $ 605,378
Marketable securities 416,602 172,266
Accounts receivable, net 263,865 203,623
Inventory 127,373 127,475
Prepaid expenses and other current assets 114,467 85,627
Total current assets 1,452,487 1,194,369
Long-term Assets:    
Property, plant and equipment, net 703,083 698,354
Operating lease right-of-use assets 139,807 143,708
Goodwill 2,366,972 2,367,120
Intangible assets, net 1,843,478 1,890,396
Other long-term assets, net 167,468 177,387
Total assets 6,673,295 6,471,334
Current liabilities:    
Accounts payable 52,980 78,816
Accrued liabilities 302,540 341,683
Operating lease liabilities, current portion 27,096 29,379
Convertible Notes Payable, Current 248,923 0
Loans Payable, Current 0 50,000
Other current liabilities 37,103 14,823
Total current liabilities 668,642 514,701
Long-term liabilities:    
Convertible notes, net, less current portion 2,317,948 2,314,276
Other long-term liabilities 326,678 335,982
Operating lease liabilities, less current portion 167,665 161,070
Total liabilities 3,480,933 3,326,029
Commitments and contingencies (Note 13)
Stockholders’ equity:    
Preferred stock, $0.01 par value Authorized—5,000,000; shares issued and outstanding—no shares at June 30, 2024 and December 31, 2023 0 0
Common stock, $0.01 par value Authorized—400,000,000; shares issued and outstanding—184,668,188 and 181,364,180 shares at June 30, 2024 and December 31, 2023 1,848 1,815
Additional paid-in capital 6,786,668 6,611,237
Accumulated other comprehensive income (loss) (943) 1,428
Accumulated deficit (3,595,211) (3,469,175)
Total stockholders’ equity 3,192,362 3,145,305
Total liabilities and stockholders’ equity $ 6,673,295 $ 6,471,334
v3.24.2
Condensed Consolidated Balance Sheets (Parenthetical) - $ / shares
Jun. 30, 2024
Dec. 31, 2023
Statement of Financial Position [Abstract]    
Preferred stock, par value (in dollars per share) $ 0.01 $ 0.01
Preferred stock, authorized (in shares) 5,000,000 5,000,000
Preferred stock, issued (in shares) 0 0
Preferred stock, outstanding (in shares) 0 0
Common stock, par value (in dollars per share) $ 0.01 $ 0.01
Common stock, authorized (in shares) 400,000,000 400,000,000
Common stock, issued (in shares) 184,668,188 181,364,180
Common stock, outstanding (in shares) 184,668,188 181,364,180
v3.24.2
Condensed Consolidated Statements of Operations - USD ($)
shares in Thousands, $ in Thousands
 3 Months Ended 6 Months Ended
Jun. 30, 2024
Jun. 30, 2023
Jun. 30, 2024
Jun. 30, 2023
Income Statement [Abstract]        
Revenue $ 699,264 $ 622,093 $ 1,336,788 $ 1,224,543
Operating expenses        
Cost of sales (exclusive of amortization of acquired intangible assets) 189,848 156,991 359,949 313,857
Research and development 120,884 104,095 231,492 199,514
Sales and marketing 185,270 176,490 377,635 363,454
General and administrative 201,856 237,965 444,973 455,260
Amortization of acquired intangible assets 23,311 22,929 46,622 45,857
Impairment of long-lived assets 8,152 552 12,598 621
Total operating expenses 729,321 699,022 1,473,269 1,378,563
Other operating income 3,800 0 3,532 0
Loss from operations (26,257) (76,929) (132,949) (154,020)
Other income (expense)        
Investment income, net 11,801 4,828 18,014 5,318
Interest income (expense), net 111 (7,818) (7,832) (3,711)
Total other income (expense) 11,912 (2,990) 10,182 1,607
Net loss before tax (14,345) (79,919) (122,767) (152,413)
Income tax expense (1,463) (1,107) (3,269) (2,764)
Net loss $ (15,808) $ (81,026) $ (126,036) $ (155,177)
Increase (decrease) in net loss per share (in usd per share) $ (0.09) $ (0.45) $ (0.69) $ (0.87)
Net loss per share—basic (in usd per share) $ (0.09) $ (0.45) $ (0.69) $ (0.87)
Weighted average common shares outstanding—diluted (in shares) 184,313 180,204 183,332 179,393
Weighted average common shares outstanding—basic (in shares) 184,313 180,204 183,332 179,393
v3.24.2
Condensed Consolidated Statements of Comprehensive Loss - USD ($)
$ in Thousands
 3 Months Ended 6 Months Ended
Jun. 30, 2024
Jun. 30, 2023
Jun. 30, 2024
Jun. 30, 2023
Statement of Comprehensive Income [Abstract]        
Net loss $ (15,808) $ (81,026) $ (126,036) $ (155,177)
Other comprehensive loss, net of tax:        
Unrealized gain (loss) on available-for-sale investments (138) 937 (925) 3,904
Foreign currency adjustment (306) 59 (1,446) 609
Comprehensive loss $ (16,252) $ (80,030) $ (128,407) $ (150,664)
v3.24.2
Condensed Consolidated Statements of Stockholders' Equity - USD ($)
$ in Thousands
Total
Common Stock
Additional Paid-In Capital
Accumulated Other Comprehensive Income (Loss)
Accumulated Deficit​
Beginning balance (in shares) at Dec. 31, 2022   177,925,631      
Beginning balance at Dec. 31, 2022 $ 3,043,162 $ 1,780 $ 6,311,644 $ (5,236) $ (3,265,026)
Increase (Decrease) in Stockholders' Equity          
Exercise of common stock options (in shares)   88,228      
Exercise of common stock options, net of shares withheld for taxes 964 $ 1 963    
Stock Issued During Period, Value, Restricted Stock Award, Net of Forfeitures     (13)    
Stock Issued During Period, Shares, Restricted Stock Award, Net of Forfeitures   1,299,071      
Issuance of common stock to fund the Company's 401(k) match (in shares)   517,215      
Stock-based compensation expense 0 $ 13      
Issuance of common stock to fund the Company's 401(k) match 35,077 $ 5 35,072    
Stock-based compensation expense 49,139   49,139    
Net loss (74,151)       (74,151)
Other comprehensive income (loss) 3,517     3,517  
Ending balance (in shares) at Mar. 31, 2023   179,830,145      
Ending balance at Mar. 31, 2023 3,057,708 $ 1,799 6,396,805 (1,719) (3,339,177)
Beginning balance (in shares) at Dec. 31, 2022   177,925,631      
Beginning balance at Dec. 31, 2022 3,043,162 $ 1,780 6,311,644 (5,236) (3,265,026)
Increase (Decrease) in Stockholders' Equity          
Stock-based compensation expense 110,900        
Net loss (155,177)        
Ending balance (in shares) at Jun. 30, 2023   180,545,663      
Ending balance at Jun. 30, 2023 3,056,622 $ 1,806 6,475,742 (723) (3,420,203)
Beginning balance (in shares) at Mar. 31, 2023   179,830,145      
Beginning balance at Mar. 31, 2023 3,057,708 $ 1,799 6,396,805 (1,719) (3,339,177)
Increase (Decrease) in Stockholders' Equity          
Exercise of common stock options (in shares)   36,728      
Exercise of common stock options, net of shares withheld for taxes 852 $ 1 851    
Stock Issued During Period, Value, Restricted Stock Award, Net of Forfeitures     (1)    
Stock Issued During Period, Shares, Restricted Stock Award, Net of Forfeitures   134,002      
Stock Issued During Period, Value, Employee Stock Purchase Plan 16,344 $ 5 16,339    
Purchase of employee stock purchase plan shares (in shares)   544,453      
Issuance of common stock to fund the Company's 401(k) match (in shares)   335      
Stock-based compensation expense 0 $ 1      
Issuance of common stock to fund the Company's 401(k) match 23 $ 0 23    
Stock-based compensation expense 61,725   61,725    
Net loss (81,026)       (81,026)
Other comprehensive income (loss) 996     996  
Ending balance (in shares) at Jun. 30, 2023   180,545,663      
Ending balance at Jun. 30, 2023 $ 3,056,622 $ 1,806 6,475,742 (723) (3,420,203)
Beginning balance (in shares) at Dec. 31, 2023 181,364,180 181,364,180      
Beginning balance at Dec. 31, 2023 $ 3,145,305 $ 1,815 6,611,237 1,428 (3,469,175)
Increase (Decrease) in Stockholders' Equity          
Exercise of common stock options (in shares)   71,537      
Exercise of common stock options, net of shares withheld for taxes (1,408) $ 1 (1,409)    
Stock Issued During Period, Value, Restricted Stock Award, Net of Forfeitures (44) $ 17 (61)    
Stock Issued During Period, Shares, Restricted Stock Award, Net of Forfeitures   1,792,087      
Issuance of common stock to fund the Company's 401(k) match (in shares)   617,384      
Issuance of common stock to fund the Company's 401(k) match 40,550 $ 6 40,544    
Stock-based compensation expense 60,370   60,370    
Net loss (110,228)       (110,228)
Other comprehensive income (loss) (1,927)     (1,927)  
Ending balance (in shares) at Mar. 31, 2024   183,845,188      
Ending balance at Mar. 31, 2024 $ 3,132,618 $ 1,839 6,710,681 (499) (3,579,403)
Beginning balance (in shares) at Dec. 31, 2023 181,364,180 181,364,180      
Beginning balance at Dec. 31, 2023 $ 3,145,305 $ 1,815 6,611,237 1,428 (3,469,175)
Increase (Decrease) in Stockholders' Equity          
Stock-based compensation expense 116,900        
Net loss $ (126,036)        
Ending balance (in shares) at Jun. 30, 2024 184,668,188 184,668,188      
Ending balance at Jun. 30, 2024 $ 3,192,362 $ 1,848 6,786,668 (943) (3,595,211)
Beginning balance (in shares) at Mar. 31, 2024   183,845,188      
Beginning balance at Mar. 31, 2024 3,132,618 $ 1,839 6,710,681 (499) (3,579,403)
Increase (Decrease) in Stockholders' Equity          
Exercise of common stock options (in shares)   8,184      
Exercise of common stock options, net of shares withheld for taxes 43 $ 1 42    
Stock Issued During Period, Value, Restricted Stock Award, Net of Forfeitures (4) $ 2 (6)    
Stock Issued During Period, Shares, Restricted Stock Award, Net of Forfeitures   210,590      
Stock Issued During Period, Value, Employee Stock Purchase Plan $ 19,402 $ 6 19,396    
Purchase of employee stock purchase plan shares (in shares) 604,226        
Stock-based compensation expense $ 56,555   56,555    
Net loss (15,808)       (15,808)
Other comprehensive income (loss) $ (444)     (444)  
Ending balance (in shares) at Jun. 30, 2024 184,668,188 184,668,188      
Ending balance at Jun. 30, 2024 $ 3,192,362 $ 1,848 $ 6,786,668 $ (943) $ (3,595,211)
v3.24.2
Condensed Consolidated Statements of Stockholders' Equity (Parenthetical) - $ / shares
Jun. 30, 2024
Dec. 31, 2023
Jun. 30, 2023
Statement of Financial Position [Abstract]      
Common stock, par value (in dollars per share) $ 0.01 $ 0.01 $ 0.01
v3.24.2
Condensed Consolidated Statements of Cash Flows - USD ($)
$ in Thousands
 6 Months Ended
Jun. 30, 2024
Jun. 30, 2023
Cash flows from operating activities:    
Net loss $ (126,036) $ (155,177)
Adjustments to reconcile net loss to net cash provided by (used in) operating activities:    
Depreciation 60,319 54,325
Loss on non-marketable and marketable equity investments 1,115 4,741
Deferred tax expense 2,225 672
Stock-based compensation 116,925 110,864
Gain on settlements of convertible notes, net (10,254) (10,324)
Amortization of acquired intangible assets 46,622 45,857
Impairment of long-lived assets 12,598 621
Gain (Loss) On Contingent Consideration From Disposition Of Asset (3,532) 0
Remeasurement of contingent consideration liabilities (7,636) (4,687)
Non-cash lease expense 14,042 13,777
Other Noncash Income (Expense) (2,667) 3,965
Changes in assets and liabilities:    
Accounts receivable, net (60,901) (20,492)
Inventory, net 96 (12,531)
Operating lease liabilities (12,957) (12,766)
Accounts payable and accrued liabilities (17,865) 48,754
Other assets (2,719) 9,624
Other liabilities 9,941 4,234
Net cash provided by operating activities 24,754 62,209
Cash flows from investing activities:    
Purchases of marketable securities (324,372) (50,656)
Maturities and sales of marketable securities 80,335 270,825
Purchases of property, plant and equipment (73,515) (64,081)
Payments to Acquire Other Investments 810 6,173
Other investing activities (205) (500)
Net cash provided by (used in) investing activities (318,567) 149,415
Payment, Tax Withholding, Share-Based Payment Arrangement (1,365) 1,816
Proceeds from Stock Plans 19,402 16,344
Cash flows from financing activities:    
Proceeds from issuance of convertible notes 266,750 137,976
Repayments of Accounts Receivable Securitization (50,000) 0
Other financing activities (13,186) (6,499)
Net cash provided by financing activities 221,601 149,637
Effects of exchange rate changes on cash and cash equivalents (1,446) 609
Net increase (decrease) in cash, cash equivalents and restricted cash (73,658) 361,870
Cash, cash equivalents and restricted cash, beginning of period 609,675 242,790
Cash, cash equivalents and restricted cash, end of period 536,017 604,660
Supplemental disclosure of non-cash investing and financing activities    
Property, plant and equipment acquired but not paid 12,442 7,850
Supplemental disclosure of cash flow information:    
Interest paid 11,971 7,385
Reconciliation of cash, cash equivalents and restricted cash:    
Cash and cash equivalents 530,180 604,363
Restricted cash — included in other long-term assets, net 5,837 297
Total cash, cash equivalents and restricted cash $ 536,017 $ 604,660
v3.24.2
SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES
 6 Months Ended
Jun. 30, 2024
Accounting Policies [Abstract]  
SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES
Business
Exact Sciences Corporation (together with its subsidiaries, “Exact,” or the “Company”) was incorporated in February 1995. A leading provider of cancer screening and diagnostic tests, Exact Sciences gives patients and health care professionals the clarity needed to take life-changing action earlier. Building on the success of the Cologuard® and Oncotype DX® tests, Exact Sciences is investing in its pipeline to develop innovative solutions for use before, during, and after a cancer diagnosis.
Basis of Presentation and Principles of Consolidation
The accompanying condensed consolidated financial statements, which include the accounts of the Company and those of its wholly owned subsidiaries and variable interest entities, are unaudited and have been prepared on a basis substantially consistent with the Company’s audited financial statements and notes as of and for the year ended December 31, 2023 included in the Company’s Annual Report on Form 10-K (the “2023 Form 10-K”). All intercompany transactions and balances have been eliminated upon consolidation. These condensed consolidated financial statements are prepared in conformity with accounting principles generally accepted (“GAAP”) in the United States of America (“U.S.”) and follow the requirements of the Securities and Exchange Commission (“SEC”) for interim reporting. In the opinion of management, the accompanying unaudited condensed consolidated financial statements contain all adjustments (consisting only of adjustments of a normal and recurring nature) considered necessary for a fair statement of its financial position, operating results and cash flows for the periods presented. The condensed consolidated balance sheet at December 31, 2023 has been derived from audited financial statements, but does not contain all of the footnote disclosures from the 2023 Form 10-K. The results of the Company’s operations for any interim period are not necessarily indicative of the results of the Company’s operations for any other interim period or for a full fiscal year. The statements should be read in conjunction with the audited financial statements and related notes included in the 2023 Form 10-K.
Use of Estimates
The preparation of the condensed consolidated financial statements in conformity with GAAP requires management to make estimates and assumptions that affect the reported amounts of assets and liabilities and disclosure of contingent assets and liabilities at the date of the financial statements and the reported amounts of revenues and expenses during the reporting period. Critical accounting policies are those that affect the Company’s financial statements materially and involve difficult, subjective or complex judgments by management, and actual results could differ from those estimates. These estimates include revenue recognition, valuation of intangible assets and goodwill, contingent consideration, and accounting for income taxes. The Company’s critical accounting policies and estimates are explained further in the notes to the condensed consolidated financial statements in this Quarterly Report on Form 10-Q and the 2023 Form 10-K.
Significant Accounting Policies
During the six months ended June 30, 2024, there were no changes to the Company’s significant accounting policies as described in the Company’s 2023 Form 10-K, except as described in the Recently Adopted Accounting Pronouncements sections below.
Recent Accounting Pronouncements
Recently Adopted Accounting Pronouncements
In March 2024, the Financial Accounting Standards Board (“FASB”) issued Accounting Standards Update (“ASU”) No. 2024-02: Codification Improvement – Amendments to Remove References to the Concepts Statements. This update amends the Accounting Standards Codification (“ASC”) to remove references to various FASB Concepts Statements. The Company early adopted and prospectively applied the amendments in this update during the first quarter of fiscal year 2024. There was no significant impact to the Company’s condensed consolidated financial statements.
Recently Issued Accounting Pronouncements Not Yet Adopted
In October 2023, the FASB issued ASU No. 2023-06, Disclosure Improvements: Codification Amendments in Response to the SEC’s Disclosure Update and Simplification Initiative. This update modifies the disclosure or presentation requirements of a variety of topics in the ASC to conform with certain SEC amendments in Release No. 33-10532, Disclosure Update and Simplification. The amendments in this update should be applied prospectively, and the effective date for each amendment will be the date on which the SEC’s removal of that related disclosure from Regulation S-X or S-K becomes effective. However, if the SEC has not removed the related disclosure from its regulations by June 30, 2027, the amendments will be removed from the Codification and not become effective. Early adoption is prohibited. The Company is currently evaluating the potential impact of this guidance on its condensed consolidated financial statements.
In November 2023, the FASB issued ASU No. 2023-07, Segment Reporting (Topic 280): Improvements to Reportable Segment Disclosures. This update improves reportable segment disclosure requirements, primarily through enhanced disclosures of significant segment expenses. The amendments in this update should be applied retrospectively to all prior periods presented in the consolidated financial statements and are effective for fiscal years beginning after December 31, 2023 and interim periods within fiscal years beginning after December 31, 2024. Early adoption is permitted. The Company is currently evaluating the potential impact of this guidance on its condensed consolidated financial statements.
In December 2023, the FASB issued ASU No. 2023-09, Income Taxes (Topic 740): Improvement to Income Tax Disclosures. This update improves income tax disclosure requirements, primarily through enhanced transparency and decision usefulness of disclosures. The amendments in this update should be applied prospectively with the option to apply retrospectively and are effective for fiscal years beginning after December 15, 2024. Early adoption is permitted. The Company is currently evaluating the potential impact of this guidance on its condensed consolidated financial statements.
Net Loss Per Share
Basic net loss per common share (“EPS”) was determined by dividing net loss applicable to common stockholders by the weighted average common shares outstanding during the period. Basic and diluted net loss per share is the same because all outstanding common stock equivalents have been excluded, as they are anti-dilutive as a result of the Company’s losses.
The following potentially issuable common shares were not included in the computation of diluted net loss per share because they would have an anti-dilutive effect due to net losses for each period:
June 30,
(In thousands)20242023
Shares issuable upon conversion of convertible notes26,526 23,231 
Shares issuable upon the release of restricted stock awards7,781 6,590 
Shares issuable upon the release of performance share units2,104 1,569 
Shares issuable upon exercise of stock options1,128 1,366 
37,539 32,756 
v3.24.2
REVENUE
 6 Months Ended
Jun. 30, 2024
Revenue from Contract with Customer [Abstract]  
REVENUE REVENUE
The Company’s revenue is primarily generated by its laboratory testing services utilizing its Cologuard and Oncotype® tests. The services are considered completed upon release of a patient’s test result to the ordering healthcare provider.
The following table presents the Company’s revenues disaggregated by revenue source:
Three Months Ended June 30,Six Months Ended June 30,
(In thousands)2024202320242023
Screening
Medicare Parts B & C$195,337 $176,016 $369,127 $347,746 
Commercial283,729 245,748 537,872 478,781 
Other52,540 41,023 99,405 79,455 
Total Screening531,606 462,787 1,006,404 905,982 
Precision Oncology
Medicare Parts B & C$47,467 $47,588 $95,517 $94,969 
Commercial49,187 46,212 95,887 91,144 
International46,722 35,586 91,255 72,854 
Other24,282 27,788 47,725 53,639 
Total Precision Oncology167,658 157,174 330,384 312,606 
COVID-19 Testing$— $2,132 $— $5,955 
Total$699,264 $622,093 $1,336,788 $1,224,543 
Screening revenue primarily includes laboratory service revenue from Cologuard and Prevention Genetics, LLC (“PreventionGenetics”) tests while Precision Oncology revenue primarily includes laboratory service revenue from global Oncotype DX and therapy selection tests.
At each reporting period end, the Company conducts an analysis of the estimates used to calculate the transaction price to determine whether any new information available impacts those estimates made in prior reporting periods. Adjustments to revenue recognized during the period relating to prior period estimates were less than 1% of revenue recorded in the Company’s condensed consolidated statement of operations for the three and six months ended June 30, 2024. Adjustments to revenue recognized during the period relating to prior period estimates were less than 2% of revenue recorded in the Company’s condensed consolidated statement of operations for the three and six months ended June 30, 2023.
The Company’s deferred revenue, which is reported in other current liabilities in the Company’s condensed consolidated balance sheets, was not significant as of June 30, 2024 and December 31, 2023.
Revenue recognized for the three and six months ended June 30, 2024 and 2023 that was included in the deferred revenue balance at the beginning of the period was not significant.
v3.24.2
MARKETABLE SECURITIES
 6 Months Ended
Jun. 30, 2024
Cash and Cash Equivalents [Abstract]  
MARKETABLE SECURITIES MARKETABLE SECURITIES
The following table sets forth the Company’s cash, cash equivalents, and marketable securities at June 30, 2024 and December 31, 2023:
(In thousands)June 30, 2024December 31, 2023
Cash and cash equivalents
Cash and money market$519,836 $530,100 
Cash equivalents10,344 75,278 
Total cash and cash equivalents530,180 605,378 
Marketable securities
Available-for-sale debt securities$414,271 $168,425 
Equity securities2,331 3,841 
Total marketable securities416,602 172,266 
Total cash, cash equivalents and marketable securities$946,782 $777,644 
Available-for-sale debt securities, including the classification within the condensed consolidated balance sheet at June 30, 2024, consisted of the following:
(In thousands)Amortized CostGains in Accumulated Other Comprehensive Income (Loss) (1)Losses in Accumulated Other Comprehensive Income (Loss) (1)Estimated Fair Value
Cash equivalents
U.S. government agency securities$10,344 $— $— $10,344 
Total cash equivalents10,344 — — 10,344 
Marketable securities
Corporate bonds$203,728 $160 $(600)$203,288 
U.S. government agency securities118,753 3 (130)118,626 
Asset backed securities87,718 21 (325)87,414 
Commercial paper4,943 — — 4,943 
Total marketable securities415,142 184 (1,055)414,271 
Total available-for-sale securities$425,486 $184 $(1,055)$424,615 
______________
(1)There was no tax impact from the gains and losses in accumulated other comprehensive income (loss) (“AOCI”).
Available-for-sale debt securities, including the classification within the condensed consolidated balance sheet at December 31, 2023, consisted of the following:
(In thousands)Amortized CostGains in Accumulated Other Comprehensive Income (Loss) (1) Losses in Accumulated Other Comprehensive Income (Loss) (1)Estimated Fair Value
Cash equivalents
Commercial paper$72,243 $— $— $72,243 
U.S. government agency securities3,035 — — 3,035 
Total cash equivalents75,278 — — 75,278 
Marketable securities
U.S. government agency securities$56,594 $166 $(44)$56,716 
Corporate bonds55,712 175 (59)55,828 
Asset backed securities35,081 65 (249)34,897 
Commercial paper
20,984 — — 20,984 
Total marketable securities168,371 406 (352)168,425 
Total available-for-sale securities$243,649 $406 $(352)$243,703 
______________
(1)There was no tax impact from the gains and losses in AOCI.
The following table summarizes contractual underlying maturities of the Company’s available-for-sale debt securities at June 30, 2024:
Due one year or lessDue after one year through five years
(In thousands)CostFair ValueCostFair Value
Cash equivalents
U.S. government agency securities$10,344 $10,344 $— $— 
Total cash equivalents10,344 10,344 — — 
Marketable securities
U.S. government agency securities$108,950 $108,844 $9,803 $9,782 
Corporate bonds46,393 46,288 157,335 157,000 
Asset backed securities5,901 5,892 81,817 81,522 
Commercial paper
4,943 4,943 — — 
Total marketable securities166,187 165,967 248,955 248,304 
Total available-for-sale securities$176,531 $176,311 $248,955 $248,304 
The following table summarizes the gross unrealized losses and fair values of available-for-sale debt securities in an unrealized loss position as of June 30, 2024 aggregated by investment category and length of time those individual securities have been in a continuous unrealized loss position:
Less than one yearOne year or greaterTotal
(In thousands)Fair ValueGross Unrealized LossFair ValueGross Unrealized LossFair ValueGross Unrealized Loss
Marketable securities
Corporate bonds$129,953 $(578)$4,720 $(22)$134,673 $(600)
U.S. government agency securities108,835 (108)3,913 (22)112,748 (130)
Asset backed securities53,722 (211)6,532 (114)60,254 (325)
Total available-for-sale securities$292,510 $(897)$15,165 $(158)$307,675 $(1,055)
The Company evaluates investments that are in an unrealized loss position for impairment as a result of credit loss. It was determined that no credit losses exist as of June 30, 2024 and December 31, 2023 because the change in market value for those securities in an unrealized loss position resulted from fluctuating interest rates rather than a deterioration of the credit worthiness of the issuers.
The gains and losses recorded on available-for-sale debt securities and equity securities are included in investment income, net in the Company’s condensed consolidated statements of operations. The gains and losses recorded were not material for the three and six months ended June 30, 2024 and 2023.
v3.24.2
INVENTORY
 6 Months Ended
Jun. 30, 2024
Inventory Disclosure [Abstract]  
INVENTORY INVENTORY
Inventory consisted of the following:
(In thousands)June 30, 2024December 31, 2023
Raw materials$52,363 $58,593 
Semi-finished and finished goods75,010 68,882 
Total inventory$127,373 $127,475 
v3.24.2
PROPERTY, PLANT AND EQUIPMENT
 6 Months Ended
Jun. 30, 2024
Property, Plant and Equipment [Abstract]  
PROPERTY, PLANT AND EQUIPMENT PROPERTY, PLANT AND EQUIPMENT
The carrying value and estimated useful lives of property, plant and equipment are as follows:
(In thousands)Estimated Useful LifeJune 30, 2024December 31, 2023
Property, plant and equipment
Landn/a$4,716 $4,716 
Leasehold and building improvements(1)228,513 214,562 
Land improvements15 years6,747 6,729 
Buildings
30 - 40 years
290,777 290,777 
Computer equipment and computer software3 years198,247 168,131 
Machinery and equipment
3 - 10 years
308,052 290,294 
Furniture and fixtures
3 - 10 years
36,278 35,756 
Assets under constructionn/a100,653 104,592 
Property, plant and equipment, at cost1,173,983 1,115,557 
Accumulated depreciation(470,900)(417,203)
Property, plant and equipment, net$703,083 $698,354 
______________
(1)Lesser of remaining lease term, building life, or estimated useful life.
Depreciation expense for the three months ended June 30, 2024 and 2023 was $29.7 million and $27.5 million, respectively. Depreciation expense for the six months ended June 30, 2024 and 2023 was $60.3 million and $54.3 million, respectively.
At June 30, 2024, the Company had $100.7 million of assets under construction, which consisted of $62.6 million in machinery and equipment, $24.8 million in capitalized costs related to software projects, $8.1 million in leasehold and building improvements, $5.1 million related to buildings, and minimal furniture and fixtures. Depreciation will begin on these assets once they are placed into service upon completion.
v3.24.2
INTANGIBLE ASSETS AND GOODWILL
 6 Months Ended
Jun. 30, 2024
Goodwill and Intangible Assets Disclosure [Abstract]  
INTANGIBLE ASSETS AND GOODWILL INTANGIBLE ASSETS AND GOODWILL
Intangible Assets
The following table summarizes the net-book-value and estimated remaining life of the Company’s intangible assets as of June 30, 2024:
(In thousands)Weighted Average Remaining Life (Years)CostAccumulated Amortization
Net Balance at June 30, 2024
Finite-lived intangible assets
Trade name11.2$104,000 $(31,528)$72,472 
Customer relationships6.54,000 (1,111)2,889 
Patents and licenses5.911,542 (10,324)1,218 
Acquired developed technology (1)6.8887,352 (370,453)516,899 
Total finite-lived intangible assets1,006,894 (413,416)593,478 
In-process research and developmentn/a1,250,000 — 1,250,000 
Total intangible assets$2,256,894 $(413,416)$1,843,478 
The following table summarizes the net-book-value and estimated remaining life of the Company’s intangible assets as of December 31, 2023:
(In thousands)Weighted Average Remaining Life (Years)CostAccumulated Amortization
Net balance at December 31, 2023
Finite-lived intangible assets
Trade name11.6$104,000 $(27,903)$76,097 
Customer relationships7.04,000 (889)3,111 
Patents and licenses4.511,542 (9,600)1,942 
Acquired developed technology (1)7.3887,789 (328,543)559,246 
Total finite-lived intangible assets1,007,331 (366,935)640,396 
In-process research and developmentn/a1,250,000 — 1,250,000 
Total intangible assets$2,257,331 $(366,935)$1,890,396 
______________
(1)The gross carrying amount includes an insignificant foreign currency translation adjustment related to the intangible asset acquired as a result of the acquisition of OmicEra Diagnostics GmbH (“OmicEra”).
As of June 30, 2024 the estimated future amortization expense associated with the Company’s finite-lived intangible assets for each of the five succeeding fiscal years is as follows:
(In thousands)
2024 (remaining six months)$46,288 
202591,860 
202690,800 
202790,800 
202890,800 
Thereafter182,930 
$593,478 
The Company’s acquired intangible assets are being amortized on a straight-line basis over their estimated useful lives.
There were no impairment losses recorded on finite-lived intangible assets during the three and six months ended June 30, 2024 and 2023. Updates to key assumptions used to calculate the fair value of the Company’s in-process research and development asset (“IPR&D”) could change the Company’s estimate that it will recover the carrying amount of the IPR&D asset in the near term.
Goodwill
The change in the carrying amount of goodwill for the periods ended June 30, 2024 and December 31, 2023 is as follows:
(In thousands)
Balance, January 1, 2023
$2,346,040 
Resolution Bioscience acquisition
20,692 
Effects of changes in foreign currency exchange rates (1)388 
Balance, December 31, 2023
2,367,120 
Resolution Bioscience acquisition adjustment
205 
Effects of changes in foreign currency exchange rates (1)(353)
Balance June 30, 2024
$2,366,972 
______________
(1)Represents the impact of foreign currency translation related to the goodwill acquired as a result of the acquisition of OmicEra.
There were no impairment losses for the three and six months ended June 30, 2024 and 2023.
v3.24.2
FAIR VALUE MEASUREMENTS
 6 Months Ended
Jun. 30, 2024
Fair Value Disclosures [Abstract]  
FAIR VALUE MEASUREMENTS FAIR VALUE MEASUREMENTS
The three levels of the fair value hierarchy established are as follows:
Level 1    Quoted prices (unadjusted) in active markets for identical assets or liabilities that the Company has the ability to access as of the reporting date. Active markets are those in which transactions for the asset or liability occur in sufficient frequency and volume to provide pricing information on an ongoing basis.
Level 2    Pricing inputs other than quoted prices in active markets included in Level 1, which are either directly or indirectly observable as of the reporting date. These include quoted prices for similar assets or liabilities in active markets and quoted prices for identical or similar assets or liabilities in markets that are not active.
Level 3    Unobservable inputs that reflect the Company’s assumptions about the assumptions that market participants would use in pricing the asset or liability. Unobservable inputs shall be used to measure fair value to the extent that observable inputs are not available.
The following table presents the Company’s fair value measurements as of June 30, 2024 along with the level within the fair value hierarchy in which the fair value measurements, in their entirety, fall.
(In thousands)Fair Value at June 30, 2024Quoted Prices in Active Markets for Identical Assets (Level 1)Significant Other Observable Inputs (Level 2)Significant Unobservable Inputs (Level 3)
Cash, cash equivalents, and restricted cash
Cash and money market$519,836 $519,836 $— $— 
U.S. government agency securities10,344 — 10,344 — 
Restricted cash (1)
5,837 5,837 — — 
Marketable securities
Corporate bonds$203,288 $— $203,288 $— 
U.S. government agency securities118,626 — 118,626 — 
Asset backed securities87,414 — 87,414 — 
Commercial paper4,943 — 4,943 — 
Equity securities2,331 2,331 — — 
Non-marketable securities$1,057 $— $— $1,057 
Liabilities
Contingent consideration$(277,921)$— $— $(277,921)
Total$675,755 $528,004 $424,615 $(276,864)
The following table presents the Company’s fair value measurements as of December 31, 2023 along with the level within the fair value hierarchy in which the fair value measurements, in their entirety, fall.
(In thousands)Fair Value at December 31, 2023Quoted Prices in Active Markets for Identical Assets (Level 1)Significant Other Observable Inputs (Level 2)Significant Unobservable Inputs (Level 3)
Cash, cash equivalents and restricted cash
Cash and money market$530,100 $530,100 $— $— 
Commercial paper72,243 — 72,243 — 
Restricted cash (1)
4,297 4,297 — — 
U.S. government agency securities3,035 — 3,035 — 
Marketable securities
U.S. government agency securities$56,716 $— $56,716 $— 
Corporate bonds55,828 — 55,828 — 
Asset backed securities34,897 — 34,897 — 
Commercial paper20,984 — 20,984 — 
Equity securities3,841 3,841 — — 
Non-marketable securities$7,650 $— $— $7,650 
Liabilities
Contingent consideration$(288,657)$— $— $(288,657)
Total$500,934 $538,238 $243,703 $(281,007)
_________________________________
(1)Restricted cash primarily represents cash held by a third-party financial institution as part of a cash collateral agreement related to the Company’s credit card program. The restrictions will lapse upon the termination of the agreements or the removal of the cash collateral requirement by the third-parties.
There have been no material changes in valuation techniques or transfers between fair value measurement levels during the three and six months ended June 30, 2024. The fair value of Level 2 instruments classified as cash equivalents and marketable debt securities are valued using a third-party pricing agency where the valuation is based on observable inputs including pricing for similar assets and other observable market factors.
The Company has elected the fair value option under the income approach to measure certain Level 3 non-marketable securities. Gains and losses recorded on non-marketable securities are included in investment income, net in the condensed consolidated statement of operations. The following table provides a reconciliation of the beginning and ending balances of non-marketable securities valued using the fair value option:
(In thousands)Non-Marketable Securities
Beginning balance, January 1, 2024
$7,650 
Changes in fair value(343)
Settlement of non-marketable securities(6,250)
Ending balance, June 30, 2024
$1,057 
Contingent Consideration Liabilities
The fair value of the contingent consideration liabilities was $277.9 million and $288.7 million as of June 30, 2024 and December 31, 2023, respectively, of which $19.0 million was included in other current liabilities and $258.9 million was included in other long-term liabilities in the condensed consolidated balance sheet as of June 30, 2024. The contingent consideration liabilities were included in other long-term liabilities as of December 31, 2023.
The following table provides a reconciliation of the beginning and ending balances of contingent consideration:
(In thousands)Contingent Consideration
Beginning balance, January 1, 2024
$288,657 
Changes in fair value (1)(7,636)
Payments (2)
(3,100)
Ending balance, June 30, 2024
$277,921 
______________
(1)The change in fair value of the contingent consideration liability was an increase of $4.2 million and a reduction of $4.7 million for the three and six months ended June 30, 2023, respectively, which is included in general and administrative expenses in the condensed consolidated statement of operations.
(2)Payment was made in the second quarter of 2024 to settle the contingent consideration liability previously recorded related to the Company’s acquisition of OmicEra.
This fair value measurement of contingent consideration is categorized as a Level 3 liability, as the measurement amount is based primarily on significant inputs not observable in the market.
The fair value of the contingent consideration liabilities recorded from the Company’s acquisitions of Thrive Earlier Detection Corporation (“Thrive”), Ashion Analytics, LLC (“Ashion”), and OmicEra related to regulatory and product development milestones was $277.9 million and $288.7 million as of June 30, 2024 and December 31, 2023, respectively. The Company evaluates the fair value of the expected contingent consideration and the corresponding liabilities related to the regulatory and product development milestones using the probability-weighted scenario based discounted cash flow model, which is consistent with the initial measurement of the expected contingent consideration liabilities. Probabilities of success are applied to each potential scenario and the resulting values are discounted using a present-value factor. The passage of time in addition to changes in projected milestone achievement timing, present-value factor, the degree of achievement, if applicable, and probabilities of success may result in adjustments to the fair value measurement. The fair value of the contingent consideration liability recorded related to regulatory and product development milestones was determined using a weighted average probability of success of 90% and 89% as of June 30, 2024 and December 31, 2023, respectively, and a weighted average present-value factor of 6.1% and 5.8% as of June 30, 2024 and December 31, 2023, respectively. The projected fiscal year of payment range is from 2025 to 2031. Unobservable inputs were weighted by the relative fair value of the contingent consideration liabilities.
The revenue milestone associated with the Ashion acquisition is not expected to be achieved and therefore no liability has been recorded for this milestone.
Non-Marketable Equity Investments
Non-marketable equity securities without readily determinable fair values, which are classified as a component of other long-term assets, net, had the following cumulative upward and downward adjustments and aggregate carrying amounts:
(In thousands)
June 30, 2024June 30, 2023
Cumulative upward adjustments (1)
$5,102 $779 
Cumulative downward adjustments and impairments (2)
15,071 12,528 
Aggregate carrying value (3)
52,227 34,197 
_________________________________
(1)    There were no material upward adjustments recorded on non-marketable equity securities held for the three and six months ended June 30, 2024 and 2023.
(2)    There were no material downward adjustments or impairments recorded on non-marketable equity securities held for the three and six months ended June 30, 2024 and 2023, respectively.
(3)    The aggregate carrying value of non-marketable equity securities was $46.0 million as of December 31, 2023.
There were no material realized gains or losses recorded during the three and six months ended June 30, 2024 and 2023.
The Company has committed capital to venture capital investment funds of $18.0 million, of which $11.8 million remains callable through 2033 as of June 30, 2024. The aggregate carrying amount of these funds, which are classified as a component of other long-term assets, net in the Company’s condensed consolidated balance sheets, were $6.8 million and $5.2 million as of June 30, 2024 and December 31, 2023, respectively.
Derivative Financial Instruments
The Company enters into foreign currency forward contracts on the last day of each month to mitigate the impact of adverse movements in foreign exchange rates related to the remeasurement of monetary assets and liabilities and hedge the Company’s foreign currency exchange rate exposure. As of June 30, 2024 and December 31, 2023 the Company had open foreign currency forward contracts with notional amounts of $45.2 million and $39.5 million, respectively. The Company's foreign exchange derivative instruments are classified as Level 2 within the fair value hierarchy as they are valued using inputs that are observable in the market or can be derived principally from or corroborated by observable market data. The fair value of the open foreign currency forward contracts was zero at June 30, 2024 and December 31, 2023 and there were no gains or losses recorded to adjust the fair value of the open foreign currency contract held as of June 30, 2024. The contracts are closed subsequent to each month-end, and the gains and losses recorded from the contracts were not significant for the three and six months ended June 30, 2024 and 2023.
v3.24.2
LONG-TERM DEBT
 6 Months Ended
Jun. 30, 2024
Debt Disclosure [Abstract]  
LONG-TERM DEBT LONG-TERM DEBT
Accounts Receivable Securitization Facility
On June 29, 2022, the Company, through a wholly-owned special purpose entity, Exact Receivables LLC (“Exact Receivables”) entered into an accounts receivable securitization program (the “Securitization Facility”) with PNC Bank, National Association (“PNC”), with a scheduled maturity date of June 29, 2024. The Securitization Facility provided Exact Receivables with a revolving line-of-credit of up to $150.0 million of borrowing capacity, subject to certain borrowing base requirements, by collateralizing a security interest in the domestic customer accounts receivable of certain wholly-owned subsidiaries of the Company. The amount available under the Securitization Facility fluctuated over time based on the total amount of eligible customer accounts receivable generated by the Company during the normal course of operations. The Securitization Facility required the Company to maintain minimum borrowings under the facility of $50.0 million. The debt issuance costs incurred related to the Securitization Facility were not significant and were amortized over the life of the Securitization Facility through interest expense within the condensed consolidated statements of operations.
In connection with the Securitization Facility, the Company also entered into two Receivables Purchase Agreements (“Receivable Purchase Agreements”) on June 29, 2022. The Receivable Purchase Agreements were among the Company and certain wholly-owned subsidiaries of the Company, and between the Company and Exact Receivables. Under the agreements, the wholly-owned subsidiaries sold all of their right, title and interest in their accounts receivables to Exact Receivables. The receivables were used to collateralize borrowings made under the Securitization Facility. The Company retained the responsibility of servicing the accounts receivable balances pledged as collateral under the Securitization Facility and provided a performance guaranty.
Upon the maturity of the Securitization Facility in June 2024, the Company repaid the previously outstanding balance of $50.0 million in full. As of December 31, 2023, the Company had an outstanding balance of $50.0 million, which was included in debt, current portion on the Company’s condensed consolidated balance sheet. Prior to the repayment, the outstanding balance accrued interest at a rate equal to a daily secured overnight financing rate (“SOFR”) plus a SOFR adjustment and an applicable margin. The interest rate was 6.89% as of the maturity date.
Revolving Loan Agreement
During November 2021, the Company entered into a revolving loan agreement (the “Revolving Loan Agreement”) with PNC. The Revolving Loan Agreement provides the Company with a revolving line of credit of up to $150.0 million (the “Revolver”). The Revolver is collateralized by the Company’s marketable securities held by PNC, which must continue to maintain a minimum market value of $150.0 million. The Revolver is available for general working capital purposes and all other lawful corporate purposes. In addition, the Company may request, in lieu of cash advances, letters of credit with an aggregate stated amount outstanding not to exceed $20.0 million. The availability of advances under the line of credit will be reduced by the stated amount of each letter of credit issued and outstanding.
Borrowings under the Revolving Loan Agreement accrue interest at an annual rate equal to the sum of the daily Bloomberg Short-Term Bank Yield Index Rate plus the applicable margin of 0.60%. Loans under the Revolving Loan Agreement may be prepaid at any time without penalty. In October 2022, the Revolving Loan Agreement was amended to extend the maturity date from November 5, 2023 to November 5, 2025. There were no other amendments to the Revolver.
The Company has agreed to various financial covenants under the Revolving Loan Agreement, and as of June 30, 2024, the Company is in compliance with all covenants.
In December 2021 and January 2023, PNC issued letters of credit of $2.9 million and $1.5 million, respectively, which reduced the amount available for cash advances under the line of credit to $145.6 million as of June 30, 2024 and December 31, 2023. As of June 30, 2024 and December 31, 2023, the Company has not drawn funds from, nor are any amounts outstanding under, the Revolving Loan Agreement.
v3.24.2
CONVERTIBLE NOTES
 6 Months Ended
Jun. 30, 2024
CONVERTIBLE NOTES [Abstract]  
CONVERTIBLE NOTES CONVERTIBLE NOTES
Convertible note obligations included in the condensed consolidated balance sheet consisted of the following as of June 30, 2024:
Fair Value (1)
(In thousands)Principal AmountUnamortized Debt Discount and Issuance CostsNet Carrying AmountAmountLeveling
2031 Convertible Notes - 1.750%
$620,709 $(14,633)$606,076 $510,335 2
2030 Convertible Notes - 2.000%
572,993 (3,998)568,995 513,373 2
2028 Convertible Notes - 0.375%
589,380 (5,741)583,639 482,702 2
2027 Convertible Notes - 0.375%
563,822 (4,584)559,238 494,872 2
2025 Convertible Notes - 1.000% (2)
249,172 (249)248,923 242,943 2
Convertible note obligations included in the condensed consolidated balance sheet consisted of the following as of December 31, 2023:
Fair Value (1)
(In thousands)Principal AmountUnamortized Debt Discount and Issuance CostsNet Carrying AmountAmountLeveling
2030 Convertible Notes - 2.000%
$572,993 $(4,349)$568,644 $684,475 2
2028 Convertible Notes - 0.375%
949,042 (10,499)938,543 887,354 2
2027 Convertible Notes - 0.375%
563,822 (5,429)558,393 549,839 2
2025 Convertible Notes - 1.000%
249,172 (476)248,696 293,300 2
______________
(1)The fair values are based on observable market prices for this debt, which is traded in less active markets and therefore is classified as a Level 2 fair value measurement.
(2)The Company’s convertible notes due in 2025 (the “2025 Notes”) mature on January 15, 2025 and are included in convertible notes, net, current portion on the condensed consolidated balance sheet as of June 30, 2024. The 2025 Notes were included in convertible notes, net, less current portion as of December 31, 2023.
Issuances and Settlements
In February 2023, the Company entered into a privately negotiated exchange and purchase agreement with a single holder of certain of the Company’s convertible notes due in 2027 (the “2027 Notes”) and 2028 (the “2028 Notes”). The Company issued the holder $500.0 million aggregate principal amount of 2.0% Convertible Notes due in 2030 (the “2030 Notes”) in exchange for $183.7 million of aggregate principal of 2027 Notes, $201.0 million of aggregate principal of 2028 Notes, and $138.0 million of cash. The extinguishment resulted in a gain on settlement of convertible notes of $17.7 million, which is included in interest income (expense), net in the condensed consolidated statement of operations for the six months ended June 30, 2023. The gain represents the difference between (i) the fair value of the consideration transferred and (ii) the carrying value of the debt at the time of exchange.
In March 2023, the Company entered into a privately negotiated exchange agreement with two holders of certain of the 2025 Notes. The Company issued the holder $73.0 million aggregate principal amount of 2030 Notes in exchange for $65.8 million of aggregate principal of 2025 Notes. The extinguishment resulted in a loss on settlement of convertible notes of $7.4 million, which is included in interest income (expense), net in the condensed consolidated statement of operations for the six months ended June 30, 2023. The loss represents the difference between (i) the fair value of the consideration transferred and (ii) the carrying value of the debt at the time of exchange.
The net proceeds from the issuance of the 2030 Notes were approximately $133.0 million, after deducting commissions and offering expenses payable by the Company.
The 2030 Notes will mature on March 1, 2030 and bear interest at a rate of 2.0% per year, payable semi-annually in arrears on March 1 and September 1 of each year, beginning on September 1, 2023.
In April 2024, the Company entered into a privately negotiated exchange and purchase agreement with certain holders of the Company’s 2028 Notes. The Company issued $620.7 million aggregate principal amount of 1.75% Convertible Notes due in 2031 (the “2031 Notes” and, collectively with the 2025 Notes, 2027 Notes, 2028 Notes, and 2030 Notes, the “Notes”) in exchange for $359.7 million of aggregate principal of 2028 Notes, and $266.8 million of cash after deducting underwriting discounts. The extinguishment resulted in a gain on settlement of convertible notes of $10.3 million, which is included in interest income (expense), net in the condensed consolidated statement of operations for the three and six months ended June 30, 2024. The gain represents the difference between (i) the fair value of the consideration transferred and (ii) the carrying value of the debt at the time of exchange.
The net proceeds from the issuance of the 2031 Notes were approximately $259.8 million, after deducting commissions and offering expenses payable by the Company.
The 2031 Notes will mature on April 15, 2031 and bear interest at a rate of 1.75% per year, payable semi-annually in arrears on October 15 and April 15 of each year, beginning on October 15, 2024. The Company has the ability to repurchase the 2031 Notes after April 17, 2029 upon the occurrence of certain events and during certain periods, as set forth in the Indenture filed at the time of the offering.
Summary of Conversion Features
Until the six-months immediately preceding the maturity date of the applicable series of the Company’s convertible notes, each series of Notes is convertible only upon the occurrence of certain events and during certain periods, as set forth in the Indentures filed at the time of the original offerings. On or after the date that is six-months immediately preceding the maturity date of the applicable series of Notes until the close of business on the second scheduled trading day immediately preceding the maturity date, holders may convert such Notes at any time. The Notes will be convertible into cash, shares of the Company’s common stock (plus, if applicable, cash in lieu of any fractional share), or a combination of cash and shares of the Company’s common stock, at the Company’s election.
It is the Company’s intent to settle all conversions through combination settlement. The initial conversion rate is 13.26, 8.96, 8.21, 12.37, and 10.06 shares of common stock per $1,000 principal amount for the 2025 Notes, 2027 Notes, 2028 Notes, 2030 Notes, and 2031 Notes, respectively, which is equivalent to an initial conversion price of approximately $75.43, $111.66, $121.84, $80.83, and $99.36 per share of the Company’s common stock for the 2025 Notes, 2027 Notes, 2028 Notes, 2030 Notes, and 2031 Notes, respectively. The 2025 Notes, 2027 Notes, 2028 Notes, 2030 Notes, and 2031 Notes are potentially convertible into up to 3.3 million, 5.0 million, 4.8 million, 7.1 million, and 6.2 million shares, respectively. The conversion rate is subject to adjustment upon the occurrence of certain specified events as set forth in the Indentures filed at the time of the original offerings but will not be adjusted for accrued and unpaid interest. In addition, holders of the Notes who convert their Notes in connection with a “make-whole fundamental change” (as defined in the Indentures), will, under certain circumstances, be entitled to an increase in the conversion rate.
If the Company undergoes a “fundamental change” (as defined in the Indentures), holders of the Notes may require the Company to repurchase for cash all or part of their Notes at a repurchase price equal to 100% of the principal amount of the Notes to be repurchased, plus accrued and unpaid interest.
Based on the closing price of the Company’s common stock of $42.25 on June 30, 2024, the if-converted values on the Notes do not exceed the principal amount.
The Notes do not contain any financial or operating covenants or any restrictions on the payment of dividends, the issuance of other indebtedness, or the issuance or repurchase of securities by the Company.
Ranking of Convertible Notes
The Notes are the Company’s senior unsecured obligations and (i) rank senior in right of payment to all of its future indebtedness that is expressly subordinated in right of payment to the Notes; (ii) rank equal in right of payment to each outstanding series thereof and to all of the Company’s future liabilities that are not so subordinated, unsecured indebtedness; (iii) are effectively junior to all of the Company’s existing and future secured indebtedness and other secured obligations, to the extent of the value of the assets securing that indebtedness and other secured obligations; and (iv) are structurally subordinated to all indebtedness and other liabilities of the Company’s subsidiaries.
Issuance Costs
Issuance costs are amortized to interest expense over the term of the Notes. The following table summarizes the original issuance costs at the time of issuance for each set of Notes:
(In thousands)
2031 Convertible Notes
$6,820 
2030 Convertible Notes4,938 
2028 Convertible Notes24,453 
2027 Convertible Notes14,285 
2025 Convertible Notes17,646 
Interest Expense
Interest expense on the Notes includes the following:
Three Months Ended June 30,Six Months Ended June 30,
(In thousands)2024202320242023
Debt issuance costs amortization$1,316 $1,315 $2,631 $2,692 
Debt discount amortization264 25 289 56 
Gain on settlements of convertible notes(10,254)— (10,254)(10,324)
Coupon interest expense6,863 4,906 11,770 8,260 
Total interest expense (income) on convertible notes$(1,811)$6,246 $4,436 $684 
The following table summarizes the effective interest rates of the Notes:
Three Months Ended June 30,Six Months Ended June 30,
2024202320242023
2031 Convertible Notes
2.06 %— %2.06 %— %
2030 Convertible Notes2.12 %2.12 %2.10 %2.10 %
2028 Convertible Notes0.64 %0.64 %0.63 %0.63 %
2027 Convertible Notes0.67 %0.67 %0.67 %0.67 %
2025 Convertible Notes1.18 %1.18 %1.17 %1.18 %
The remaining period over which the unamortized debt discount will be recognized as non-cash interest expense is 0.55, 2.71, 3.67, 5.67, and 6.79 years for the 2025 Notes, 2027 Notes, 2028 Notes, 2030 Notes, and 2031 Notes, respectively.
v3.24.2
LICENSE AND COLLABORATION AGREEMENTS
 6 Months Ended
Jun. 30, 2024
LICENSE AGREEMENTS [Abstract]  
LICENSE AND COLLABORATION AGREEMENTS LICENSE AND COLLABORATION AGREEMENTS
The Company licenses certain technologies that are, or may be, incorporated into its technology under several license agreements, as well as the rights to commercialize certain diagnostic tests through collaboration agreements. Generally, the license agreements require the Company to pay single-digit royalties based on net revenues received using the technologies and may require minimum royalty amounts, milestone payments, or maintenance fees.
Mayo Foundation for Medical Education and Research
In June 2009, the Company entered into an exclusive, worldwide license agreement with the Mayo Foundation for Medical Education and Research (“Mayo”), under which Mayo granted the Company an exclusive, worldwide license to certain Mayo patents and patent applications, as well as a non-exclusive, worldwide license with regard to certain Mayo know-how. The scope of the license covers any screening, surveillance or diagnostic test or tool for use in connection with any type of cancer, pre-cancer, disease or condition. The Company’s license agreement with Mayo was most recently amended and restated in September 2020.
The licensed Mayo patents and patent applications contain both method and composition claims that relate to sample processing, analytical testing and data analysis associated with nucleic acid screening for cancers and other diseases. The jurisdictions covered by these patents and patent applications include the U.S., Australia, Canada, the European Union, China, Japan and Korea. Under the license agreement, the Company assumed the obligation and expense of prosecuting and maintaining the licensed Mayo patents and is obligated to make commercially reasonable efforts to bring to market products using the licensed Mayo intellectual property.
Pursuant to the Company’s agreement with Mayo, the Company is required to pay Mayo a low-single-digit royalty on the Company’s net sales of current and future products using the licensed Mayo intellectual property each year during the term of the Mayo agreement.
The Company is also required to pay Mayo up to $3.0 million in sales-based milestone payments upon cumulative net sales of each product using the licensed Mayo intellectual property reaching specified levels.
The license agreement will remain in effect, unless earlier terminated by the parties in accordance with the agreement, until the last of the licensed patents expires in 2039 (or later, if certain licensed patent applications are issued). However, if the Company is still using the licensed Mayo know-how or certain Mayo-provided biological specimens or their derivatives on such expiration date, the term shall continue until the earlier of the date the Company stops using such know-how and materials and the date that is five years after the last licensed patent expires. The license agreement contains customary termination provisions and permits Mayo to terminate the license agreement if the Company sues Mayo or its affiliates, other than any such suit claiming an uncured material breach by Mayo of the license agreement.
In addition to granting the Company a license to the covered Mayo intellectual property, Mayo provides the Company with product development and research and development assistance pursuant to the license agreement and other collaborative arrangements. In September 2020, Mayo also agreed to make available certain personnel to provide such assistance through January 2025. In connection with this collaboration, the Company has incurred insignificant charges for the three months ended June 30, 2024 and 2023, respectively. The charges incurred in connection with this collaboration are recorded in research and development expenses in the Company’s condensed consolidated statements of operations.
Johns Hopkins University
Through the acquisition of Thrive, the Company acquired a worldwide exclusive license agreement with Johns Hopkins University (“JHU”) for use of several JHU patents and licensed know-how. The license is designed to enable the Company to leverage JHU proprietary data in the development and commercialization of a blood-based, multi-cancer screening test. The agreement terms would require the Company to pay single-digit sales-based royalties and up to $45.0 million in sales-based milestone payments if net sales of a licensed product using JHU proprietary data reach specified levels. The Company will record the sales-based royalties and sales-based milestones once achievement is deemed probable. The Company has not incurred charges related to the achievement of any sales-based royalties or sales-based milestones as of June 30, 2024.
Targeted Digital Sequencing (“TARDIS”) License Agreement
In January 2021, the Company entered into an exclusive, worldwide license to the proprietary TARDIS technology from The Translational Genomics Research Institute (“TGen”). Under the agreement, the Company acquired a royalty-free, worldwide exclusive license to proprietary TARDIS patents and know-how. Under the agreement, the Company was obligated to make milestone payments to TGen of up to $45.0 million in sales-based milestone payments upon cumulative net sales related to molecular residual disease (“MRD”) detection and/or treatment reaching specified levels. These payments were contingent upon achievement of these cumulative revenues on or before December 31, 2030, which was not achieved prior to the termination.
Effective May 1, 2024, the Company entered into termination agreements (the “Termination Agreements”) with TGen for the purpose of terminating the license and sponsored research agreement relating to the TARDIS technology and an additional sponsored research agreement with a broader scope (collectively, the “Original Agreements”). As part of the Termination Agreements, the Company will pay TGen $27.6 million in compensation for the termination of the Original Agreements, which will be allocated into three annual installments of $9.2 million per year beginning in the second quarter of 2024. The fair value of the termination payments as of the date of the Termination Agreements was $25.8 million, which was recorded as research and development expense in the condensed consolidated statement of operations for the three and six months ended June 30, 2024. The remaining $1.8 million in expense will be amortized on a straight-line basis through the date of the final payment in the second quarter of 2026. The Company has recorded a liability of $16.8 million representing the fair value of the remaining payments, of which $8.7 million is included in accrued liabilities and $8.1 million is included in other long-term liabilities on the condensed consolidated balance sheet as of June 30, 2024. The termination payments eliminate the Company’s obligation to pay TGen any further payments, equities, fees, costs, or other amounts that would have been due under the Original Agreements, including the milestone payments. The Company’s ongoing development efforts for its pipeline tests are not impacted by the Termination Agreements.
Broad Institute, Inc.
In June 2023, the Company entered into an exclusive license agreement with Broad Institute, Inc. (“Broad Institute”) to utilize the Minor Allele Enriched Sequencing Through Recognition Oligonucleotides (“MAESTRO”) technology in the Company’s MRD testing. Under the license agreement, the Company is obligated to make development milestone payments to Broad Institute of up to $6.5 million upon achievement of certain development milestones related to prospective MRD tests that use the MAESTRO technology. In addition, the Company is obligated to make sales-based milestone payments to Broad Institute that equate up to a mid-single-digit royalty upon the achievement of certain cumulative net sales targets of licensed products using the MAESTRO technology beginning at $500.0 million. The Company will record the development milestones once achieved and the sales milestones once achievement is deemed probable. The Company has not incurred charges related to the achievement of development milestones or sales milestones as of June 30, 2024.
Watchmaker Genomics, Inc.
In July 2023, the Company entered into a co-exclusive development and license agreement with Watchmaker Genomics, Inc. (“Watchmaker”) under which the Company granted Watchmaker a co-exclusive license to the non-bisulfite technology for the detection of methylated DNA and other epigenetic modifications (“TAPS”). TAPS is based on patents obtained by the Company through an exclusive license agreement with the Ludwig Institute for Cancer Research. Under the agreement, both parties have the right to use and develop TAPS for commercial purposes. The Company has the potential to receive up to $82.0 million in sales-based milestone payments and mid-single digit royalties based on future Watchmaker net sales of licensed products including TAPS. Additionally, Watchmaker has the right to sublicense TAPS, and the Company has the potential to receive royalties based on future Watchmaker sublicense receipts.
v3.24.2
STOCKHOLDERS' EQUITY
 6 Months Ended
Jun. 30, 2024
Equity [Abstract]  
STOCKHOLDERS' EQUITY STOCKHOLDERS’ EQUITY
Changes in Accumulated Other Comprehensive Income (Loss)
The amounts recognized in AOCI for the six months ended June 30, 2024 were as follows:
(In thousands)Cumulative Translation AdjustmentUnrealized Gain (Loss) on Securities (1)
AOCI
Balance at December 31, 2023$1,374 $54 $1,428 
Other comprehensive loss before reclassifications
(1,446)(984)(2,430)
Amounts reclassified from accumulated other comprehensive income (loss)
— 59 59 
Net current period change in accumulated other comprehensive income (loss)
(1,446)(925)(2,371)
Balance at June 30, 2024$(72)$(871)$(943)
______________
(1)There was no tax impact from the amounts recognized in AOCI for the three and six months ended June 30, 2024.
The amounts recognized in AOCI for the six months ended June 30, 2023 were as follows:
(In thousands)Cumulative Translation AdjustmentUnrealized Gain (Loss) on Securities (1)
AOCI
Balance at December 31, 2022$53 $(5,289)$(5,236)
Other comprehensive income before reclassifications
609 1,051 1,660 
Amounts reclassified from accumulated other comprehensive income (loss)
— 2,853 2,853 
Net current period change in accumulated other comprehensive income (loss)
609 3,904 4,513 
Balance at June 30, 2023$662 $(1,385)$(723)
______________
(1)There was no tax impact from the amounts recognized in AOCI for the six months ended June 30, 2023.
Amounts reclassified from AOCI for the six months ended June 30, 2024 and 2023 were as follows:
Affected Line Item in the
Statements of Operations		Six Months Ended June 30,
Details about AOCI Components (In thousands)20242023
Change in value of available-for-sale investments
Sales and maturities of available-for-sale investments
Investment income, net
$59 $2,853 
Total reclassifications$59 $2,853 
v3.24.2
STOCK-BASED COMPENSATION
 6 Months Ended
Jun. 30, 2024
Share-Based Payment Arrangement [Abstract]  
STOCK-BASED COMPENSATION STOCK-BASED COMPENSATION
Stock-Based Compensation Plans
The Company maintains the following plans for which awards were granted from or had awards outstanding in 2023: the 2010 Omnibus Long-Term Incentive Plan (as Amended and Restated effective July 27, 2017), the 2019 Omnibus Long-Term Incentive Plan, and the 2010 Employee Stock Purchase Plan. These plans are collectively referred to as the “Stock Plans” and are administered in conjunction with the Company’s Equity Award Death, Disability and Retirement Policy, which was adopted in February 2023. Refer to the Company’s 2023 Form 10-K for further information regarding this policy.
Stock-Based Compensation Expense
The Company records stock-based compensation expense in connection with the amortization of restricted stock and restricted stock unit awards (“RSUs”), performance share units (“PSUs”), stock purchase rights granted under the Company’s employee stock purchase plan (“ESPP”) and stock options granted to employees, non-employee consultants and non-employee directors. The Company recorded $56.6 million and $61.7 million in stock-based compensation expense during the three months ended June 30, 2024 and 2023, respectively. The Company recorded $116.9 million and $110.9 million in stock-based compensation expense during the six months ended June 30, 2024 and 2023, respectively.
As of June 30, 2024, there was approximately $450.0 million of expected total unrecognized compensation cost related to non-vested stock-based compensation arrangements granted under all equity compensation plans. The Company expects to recognize that cost over a weighted average period of 2.7 years.
Stock Options
A summary of stock option activity under the Stock Plans is as follows:
Option SharesWeighted Average Exercise PriceWeighted Average Remaining Contractual Term (Years)Aggregate Intrinsic Value (1)
(Aggregate intrinsic value in thousands)
Outstanding, January 1, 20241,286,173 $47.67 3.8
Exercised(141,503)15.44 
Forfeited(17,164)94.85 
Outstanding, June 30, 20241,127,506 $51.00 3.6$11,834 
Vested and expected to vest, June 30, 2024
1,127,506 $51.00 3.6$11,834 
Exercisable, June 30, 20241,127,506 $51.00 3.6$11,834 
______________
(1)The total intrinsic value of options exercised, net of shares withheld for taxes, during the six months ended June 30, 2024 and 2023 was $3.3 million and $7.0 million, respectively, determined as of the date of exercise.
Restricted Stock and Restricted Stock Units
The fair value of restricted stock and RSUs is determined on the date of grant using the closing stock price on that day.
A summary of restricted stock and RSU activity during the six months ended June 30, 2024 is as follows:
Restricted SharesWeighted Average Grant Date Fair Value (1)
Outstanding, January 1, 20246,272,763 $73.39 
Granted3,937,097 57.38 
Released (2)(1,924,514)79.93 
Forfeited(504,123)64.23 
Outstanding, June 30, 20247,781,223 $63.97 
______________
(1)The weighted average grant date fair value of the RSUs granted during the six months ended June 30, 2023 was $60.94.
(2)The fair value of RSUs vested and converted to shares of the Company’s common stock was $153.4 million and $130.5 million during the six months ended June 30, 2024 and 2023, respectively.
Performance Share Units
The Company has issued performance-based equity awards to certain employees which vest upon the achievement of certain performance goals, including financial performance targets and operational milestones.
A summary of PSU activity during the six months ended June 30, 2024 is as follows:
Performance Share Units (1)Weighted Average Grant Date Fair Value (2)
Outstanding, January 1, 20241,597,801 $92.73 
Granted913,533 63.68 
Released (3)(70,662)140.20 
Forfeited(336,852)106.06 
Outstanding, June 30, 20242,103,820 $74.25 
______________
(1)The PSUs listed above assumes attainment of maximum payout rates as set forth in the performance criteria. Applying actual or expected payout rates, the number of outstanding PSUs as of June 30, 2024 was 1,037,206.
(2)The weighted average grant date fair value of the PSUs granted during the six months ended June 30, 2023 was $79.17.
(3)The fair value of PSUs vested and converted to shares of the Company’s common stock was $9.9 million and $1.0 million for the six months ended June 30, 2024 and 2023, respectively.
Employee Stock Purchase Plan
The fair value of shares purchased during the three and six months ended June 30, 2024 and 2023 under the ESPP is based on the assumptions in the following table:
Three Months Ended June 30,Six Months Ended June 30,
2024202320242023
ESPP Shares
Risk-free interest rates
4.71% - 5.30%
4.68%
4.71% - 5.30%
4.68%
Expected term (in years)1.171.251.171.25
Expected volatility
55.67% - 63.13%
67.30%
55.67% - 63.13%
67.30%
Dividend yield
—%
—%—%—%
v3.24.2
COMMITMENTS AND CONTINGENCIES
 6 Months Ended
Jun. 30, 2024
Commitments and Contingencies Disclosure [Abstract]  
COMMITMENTS AND CONTINGENCIES COMMITMENTS AND CONTINGENCIES
Leases
Supplemental disclosure of cash flow information related to the Company’s cash and non-cash activities with its leases are as follows:
Six Months Ended June 30,
(In thousands)20242023
Cash paid for amounts included in the measurement of lease liabilities:
Operating cash flows from operating leases$19,188$19,093
Operating cash flows from finance leases612342
Finance cash flows from finance leases3,0251,561
Non-cash investing and financing activities:
Right-of-use assets obtained in exchange for new operating lease liabilities (1)$18,925$(5,375)
Right-of-use assets obtained in exchange for new finance lease liabilities13,7172,670
Weighted-average remaining lease term - operating leases (in years)7.737.20
Weighted-average remaining lease term - finance leases (in years)3.213.04
Weighted-average discount rate - operating leases6.55 %6.41 %
Weighted-average discount rate - finance leases6.78 %7.03 %
______________
(1)For the six months ended June 30, 2023, this includes reductions of $8.6 million on the carrying value of the right-of-use assets held due to a reduction of the expected lease term.
As of June 30, 2024 and December 31, 2023, the Company’s right-of-use assets from operating leases are $139.8 million and $143.7 million, respectively, which are reported in operating lease right-of-use assets in the Company’s condensed consolidated balance sheets. As of June 30, 2024, the Company has outstanding operating lease obligations of $194.8 million, of which $27.1 million is reported in operating lease liabilities, current portion and $167.7 million is reported in operating lease liabilities, less current portion in the Company’s condensed consolidated balance sheets. As of December 31, 2023, the Company had outstanding operating lease obligations of $190.4 million, of which $29.4 million is reported in operating lease liabilities, current portion and $161.1 million is reported in operating lease liabilities, less current portion in the Company’s condensed consolidated balance sheets.
As of June 30, 2024 and December 31, 2023, the Company’s right-of-use assets from finance leases are $21.4 million and $11.3 million, respectively, which are reported in other long-term assets, net in the Company’s condensed consolidated balance sheets. As of June 30, 2024, the Company has outstanding finance lease obligations of $22.3 million, of which $7.3 million is reported in other current liabilities and $15.0 million is reported in other long-term liabilities in the Company’s condensed consolidated balance sheets. As of December 31, 2023, the Company had outstanding finance lease obligations of $11.9 million, of which $4.4 million is reported in other current liabilities and $7.5 million is reported in other long-term liabilities in the Company’s condensed consolidated balance sheets.
Legal Matters
In addition to commitments and obligations incurred in the ordinary course of business, from time to time the Company may be subject to a variety of claims and legal proceedings, including legal actions for damages, governmental investigations and other matters. The Company has also instituted, and may in the future institute, additional legal proceedings to enforce its rights and seek remedies, such as monetary damages, injunctive relief and declaratory relief.
The Company accrues costs for certain legal proceedings and regulatory matters to the extent that it determines an unfavorable outcome is probable and the amount of the loss can be reasonably estimated. While such accrued costs reflect the Company’s best estimate of the probable loss for such matters, the recorded amounts may differ materially from the actual amount of any such losses. In some cases, no estimate of the possible loss or range of loss in excess of amounts accrued, if any, can be made because of the inherently unpredictable nature of legal and regulatory proceedings, which may be exacerbated by various factors, including but not limited to, that they may involve indeterminate claims for monetary damages or may involve fines, penalties or punitive damages; present novel legal theories or legal uncertainties; involve disputed facts; represent a shift in regulatory policy; involve a large number of parties, claimants or regulatory bodies; are in the early stages of the proceedings; involve a number of separate proceedings and/or a wide range of potential outcomes; or result in a change of business practices.
As of the date of this Quarterly Report on Form 10-Q, amounts accrued for legal proceedings and regulatory matters were not material. The Company believes that the ultimate outcome of any of the regulatory and legal proceedings that are currently pending against it should not have a material adverse effect on financial condition, results of operations, cash flow or liquidity. However, it is possible that in a particular quarter or annual period the Company’s financial condition, results of operations, cash flow and/or liquidity could be materially adversely affected by an ultimate unfavorable resolution of, or development in, legal and/or regulatory proceedings.
v3.24.2
WISCONSIN ECONOMIC DEVELOPMENT TAX CREDITS
 6 Months Ended
Jun. 30, 2024
WISCONSIN ECONOMIC DEVELOPMENT TAX CREDITS [Abstract]  
WISCONSIN ECONOMIC DEVELOPMENT TAX CREDITS WISCONSIN ECONOMIC DEVELOPMENT TAX CREDITS
During December 2021, the Company entered into an amended agreement (“Amended WEDC Agreement”) with the Wisconsin Economic Development Corporation (“WEDC”) to earn an additional $18.5 million in refundable tax credits on the condition that the Company expends $350.0 million in capital investments and establishes and maintains 1,300 additional full-time positions over a five-year period. The capital investment credits are earned at a rate of 10% of eligible capital investments up to a maximum of $7.0 million, while the jobs creation credits are earned annually pursuant to the agreement.
The tax credits earned are first applied against the tax liability otherwise due, and if there is no such liability present, the claim for tax credits will be reimbursed in cash to the Company. The maximum amount of the refundable tax credit to be earned for each year is fixed, and the Company earns the credits by meeting certain capital investment and job creation thresholds over the term of the agreement. Should the Company earn and receive the job creation tax credits but not maintain those full-time positions through the end of the agreement, the Company may be required to pay those credits back to the WEDC.
The Company records the earned tax credits as job creation and capital investments occurs. The tax credits earned from capital investment are recognized as a reduction to capital expenditures at the time the costs are incurred, and then as an offset to depreciation expense over the expected life of the acquired capital assets. The tax credits earned related to job creation are recognized as an offset to operational expenses in the period in which the credits are earned.
As of June 30, 2024, the Company has earned $14.3 million of the refundable tax credits under the Amended WEDC Agreement. The unpaid portion is $8.8 million, of which $4.2 million is reported in prepaid expenses and other current assets and $4.6 million is reported in other long-term assets, net in the Company’s condensed consolidated balance sheets reflecting when collection of the refundable tax credits is expected to occur. During the three and six months ended June 30, 2024 and 2023, the amounts recorded as an offset to capital expenditures and operating expenses for the tax credits earned were not significant.
v3.24.2
ACQUISITIONS AND DIVESTITURES
 6 Months Ended
Jun. 30, 2024
Business Combination, Asset Acquisition, and Joint Venture Formation [Abstract]  
ACQUISITIONS AND DIVESTITURES ACQUISITIONS AND DIVESTITURES
Business Combinations
Resolution Bioscience, Inc.
On September 12, 2023, the Company completed the acquisition of all of the outstanding capital stock of Resolution Bioscience, Inc. (“Resolution Bioscience”) from Agilent Technologies, Inc. Resolution Bioscience develops and commercializes next-generation sequencing-based precision oncology solutions through its Clinical Laboratory Improvement Amendments (“CLIA”) certified lab based in Kirkland, Washington. The acquisition provides the Company with a high-quality blood-based therapy selection platform, complementing its comprehensive, tissue-based OncoExTra® test.
Refer to the Company’s 2023 Form 10-K for detailed disclosures on the combination, including the fair value of the consideration transferred, purchase price allocation, and goodwill and intangible assets identified in the transaction. During the three and six months ended June 30, 2024, there were no significant changes to the purchase price and purchase price allocation. The measurement period remains open pending the completion of valuation procedures related to certain acquired assets and liabilities assumed, primarily in connection with the developed technology intangible asset.
Divestitures
Oncotype DX Genomic Prostate Score Test
On August 2, 2022, pursuant to an asset purchase agreement (the “Asset Purchase Agreement”) with MDxHealth SA (“MDxHealth”), the Company completed the sale of the intellectual property and know-how related to the Company’s Oncotype DX Genomic Prostate Score test (“GPS test”), which will allow the Company to focus on the highest impact projects core to the Company’s vision. On August 23, 2023, the Company and MDxHealth executed the Second Amendment to the Asset Purchase Agreement (the “Second Amendment”). Under the Second Amendment, the Company agreed to allow MDxHealth to defer the 2023 contingent consideration payment by three years in exchange for additional consideration and more favorable contingent consideration terms, including elimination of the minimum revenue thresholds previously required to be met under the Asset Purchase Agreement. Refer to the Company’s 2023 Form 10-K for additional details on the agreements.
As of June 30, 2024 and December 31, 2023, a portion of the contingent consideration is classified as a contract asset. As of June 30, 2024, the contract asset was $45.2 million, of which $24.1 million is included in prepaid expenses and other current assets and $21.1 million is included in other long-term assets, net on the condensed consolidated balance sheet. As of December 31, 2023, the contract asset was $41.7 million, which is included in other long-term assets on the condensed consolidated balance sheet. The contract asset was estimated using historical GPS test revenues by MDxHealth under the most likely method. The remaining consideration balance as of June 30, 2024 and December 31, 2023 was $31.6 million, which includes the amount earned during the 2023 earnout year and is classified as a receivable within other long-term assets, net on the condensed consolidated balance sheet. The Company recorded an insignificant contingent consideration gain for the three and six months ended June 30, 2024, which is included in other operating income in the condensed consolidated statement of operations.
v3.24.2
SEGMENT INFORMATION
 6 Months Ended
Jun. 30, 2024
Segment Reporting [Abstract]  
SEGMENT INFORMATION SEGMENT INFORMATION
Management determined that the Company functions as a single operating segment, and thus reports as a single reportable segment. This operating segment is focused on the development and global commercialization of clinical laboratory services allowing healthcare providers and patients to make individualized treatment decisions. Management assessed the financial information routinely reviewed by the Company's Chief Operating Decision Maker, its President and Chief Executive Officer, to monitor the Company's operating performance and support decisions regarding allocation of resources to its operations. Performance is continuously monitored at the consolidated level to timely identify deviations from expected results.
The following table summarizes total revenue from customers by geographic region. Product revenues are attributed to countries based on ship-to location.
Three Months Ended June 30,Six Months Ended June 30,
(In thousands)2024202320242023
United States$652,542 $586,507 $1,245,533 $1,151,689 
Outside of United States46,722 35,586 91,255 72,854 
Total revenues$699,264 $622,093 $1,336,788 $1,224,543 
Long-lived assets located in countries outside of the U.S. are not significant.
v3.24.2
INCOME TAXES
 6 Months Ended
Jun. 30, 2024
Income Tax Disclosure [Abstract]  
INCOME TAXES INCOME TAXES
The Company recorded income tax expense of $1.5 million and $1.1 million for the three months ended June 30, 2024 and 2023, respectively. The Company recorded income tax expense of $3.3 million and $2.8 million for the six months ended June 30, 2024 and 2023, respectively. The Company’s income tax expense recorded during the three and six months ended June 30, 2024 is primarily related to current foreign and state tax expense. A deferred tax liability of $19.1 million and $17.3 million was recorded as of June 30, 2024 and December 31, 2023, respectively, which is included in other long-term liabilities on the Company’s condensed consolidated balance sheet. The Company continues to maintain a full valuation allowance against its deferred tax assets based on management’s determination that it is more likely than not the benefit will not be realized.
The Company had $40.1 million and $36.4 million of unrecognized tax benefits at June 30, 2024 and December 31, 2023, respectively. These amounts have been recorded as a reduction to the Company’s deferred tax asset, if recognized they would not have an impact on the effective tax rate due to the existing valuation allowance. Certain of the Company's unrecognized tax benefits could change due to activities of various tax authorities, including possible settlement of audits, or through normal expiration of various statutes of limitations. The Company does not expect a material change in unrecognized tax benefits in the next twelve months.
As of June 30, 2024, due to the carryforward of unutilized net operating losses and research and development credits, the Company is subject to U.S. federal income tax examinations for the tax years 2000 through 2024, and to state income tax examinations for the tax years 2000 through 2024. No interest or penalties related to income taxes have been accrued or recognized as of June 30, 2024.
The Organization for Economic Co-operation and Development has endorsed a framework (“Pillar Two”) with model rules introducing a global minimum corporate tax rate via a system where multinational groups with consolidated revenue over €750.0 million are subject to a minimum effective tax rate of 15% on income arising in low-tax jurisdictions on a country-by-country basis. Many countries have implemented laws based on these model rules, with effective dates beginning January 1, 2024. These rules do not have a material impact on the Company for the current period and, as currently designed, are not expected to materially increase the Company’s global tax costs. The Company will continue to monitor U.S. and global legislative action related to Pillar Two for potential impacts.
v3.24.2
SUBSEQUENT EVENTS
 6 Months Ended
Jun. 30, 2024
Subsequent Events [Abstract]  
SUBSEQUENT EVENTS
(18) SUBSEQUENT EVENTS
On July 1, 2024, the Company entered into an exclusive license agreement with TwinStrand Biosciences, Inc. (“TwinStrand”), under which the Company will have the ability to use, commercialize, and sublicense the acquired intellectual property related to the cell free nucleic acid sequencing technology. Under the license agreement, the Company made upfront payments to TwinStrand totaling $45.0 million in July 2024. The license will be accounted for as an asset acquisition and the upfront consideration, which will be classified as an intangible asset in the condensed consolidated balance sheet, will be amortized through amortization of acquired intangible assets in the condensed consolidated statement of operations over its estimated useful life.
v3.24.2
SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES (Policies)
 6 Months Ended
Jun. 30, 2024
Accounting Policies [Abstract]  
Basis of Presentation and Principles of Consolidation
Basis of Presentation and Principles of Consolidation
The accompanying condensed consolidated financial statements, which include the accounts of the Company and those of its wholly owned subsidiaries and variable interest entities, are unaudited and have been prepared on a basis substantially consistent with the Company’s audited financial statements and notes as of and for the year ended December 31, 2023 included in the Company’s Annual Report on Form 10-K (the “2023 Form 10-K”). All intercompany transactions and balances have been eliminated upon consolidation. These condensed consolidated financial statements are prepared in conformity with accounting principles generally accepted (“GAAP”) in the United States of America (“U.S.”) and follow the requirements of the Securities and Exchange Commission (“SEC”) for interim reporting. In the opinion of management, the accompanying unaudited condensed consolidated financial statements contain all adjustments (consisting only of adjustments of a normal and recurring nature) considered necessary for a fair statement of its financial position, operating results and cash flows for the periods presented. The condensed consolidated balance sheet at December 31, 2023 has been derived from audited financial statements, but does not contain all of the footnote disclosures from the 2023 Form 10-K. The results of the Company’s operations for any interim period are not necessarily indicative of the results of the Company’s operations for any other interim period or for a full fiscal year. The statements should be read in conjunction with the audited financial statements and related notes included in the 2023 Form 10-K.
Use of Estimates
Use of Estimates
The preparation of the condensed consolidated financial statements in conformity with GAAP requires management to make estimates and assumptions that affect the reported amounts of assets and liabilities and disclosure of contingent assets and liabilities at the date of the financial statements and the reported amounts of revenues and expenses during the reporting period. Critical accounting policies are those that affect the Company’s financial statements materially and involve difficult, subjective or complex judgments by management, and actual results could differ from those estimates. These estimates include revenue recognition, valuation of intangible assets and goodwill, contingent consideration, and accounting for income taxes. The Company’s critical accounting policies and estimates are explained further in the notes to the condensed consolidated financial statements in this Quarterly Report on Form 10-Q and the 2023 Form 10-K.
Recent Accounting Pronouncements
Recent Accounting Pronouncements
Recently Adopted Accounting Pronouncements
In March 2024, the Financial Accounting Standards Board (“FASB”) issued Accounting Standards Update (“ASU”) No. 2024-02: Codification Improvement – Amendments to Remove References to the Concepts Statements. This update amends the Accounting Standards Codification (“ASC”) to remove references to various FASB Concepts Statements. The Company early adopted and prospectively applied the amendments in this update during the first quarter of fiscal year 2024. There was no significant impact to the Company’s condensed consolidated financial statements.
Recently Issued Accounting Pronouncements Not Yet Adopted
In October 2023, the FASB issued ASU No. 2023-06, Disclosure Improvements: Codification Amendments in Response to the SEC’s Disclosure Update and Simplification Initiative. This update modifies the disclosure or presentation requirements of a variety of topics in the ASC to conform with certain SEC amendments in Release No. 33-10532, Disclosure Update and Simplification. The amendments in this update should be applied prospectively, and the effective date for each amendment will be the date on which the SEC’s removal of that related disclosure from Regulation S-X or S-K becomes effective. However, if the SEC has not removed the related disclosure from its regulations by June 30, 2027, the amendments will be removed from the Codification and not become effective. Early adoption is prohibited. The Company is currently evaluating the potential impact of this guidance on its condensed consolidated financial statements.
In November 2023, the FASB issued ASU No. 2023-07, Segment Reporting (Topic 280): Improvements to Reportable Segment Disclosures. This update improves reportable segment disclosure requirements, primarily through enhanced disclosures of significant segment expenses. The amendments in this update should be applied retrospectively to all prior periods presented in the consolidated financial statements and are effective for fiscal years beginning after December 31, 2023 and interim periods within fiscal years beginning after December 31, 2024. Early adoption is permitted. The Company is currently evaluating the potential impact of this guidance on its condensed consolidated financial statements.
In December 2023, the FASB issued ASU No. 2023-09, Income Taxes (Topic 740): Improvement to Income Tax Disclosures. This update improves income tax disclosure requirements, primarily through enhanced transparency and decision usefulness of disclosures. The amendments in this update should be applied prospectively with the option to apply retrospectively and are effective for fiscal years beginning after December 15, 2024. Early adoption is permitted. The Company is currently evaluating the potential impact of this guidance on its condensed consolidated financial statements.
Net Loss Per Share
Net Loss Per Share
Basic net loss per common share (“EPS”) was determined by dividing net loss applicable to common stockholders by the weighted average common shares outstanding during the period. Basic and diluted net loss per share is the same because all outstanding common stock equivalents have been excluded, as they are anti-dilutive as a result of the Company’s losses.
v3.24.2
SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES (Tables)
 6 Months Ended
Jun. 30, 2024
Accounting Policies [Abstract]  
Schedule of Antidilutive Securities Excluded from Computation of Earnings Per Share
The following potentially issuable common shares were not included in the computation of diluted net loss per share because they would have an anti-dilutive effect due to net losses for each period:
June 30,
(In thousands)20242023
Shares issuable upon conversion of convertible notes26,526 23,231 
Shares issuable upon the release of restricted stock awards7,781 6,590 
Shares issuable upon the release of performance share units2,104 1,569 
Shares issuable upon exercise of stock options1,128 1,366 
37,539 32,756 
v3.24.2
REVENUE (Tables)
 6 Months Ended
Jun. 30, 2024
Revenue from Contract with Customer [Abstract]  
Schedule of disaggregation of revenue
The following table presents the Company’s revenues disaggregated by revenue source:
Three Months Ended June 30,Six Months Ended June 30,
(In thousands)2024202320242023
Screening
Medicare Parts B & C$195,337 $176,016 $369,127 $347,746 
Commercial283,729 245,748 537,872 478,781 
Other52,540 41,023 99,405 79,455 
Total Screening531,606 462,787 1,006,404 905,982 
Precision Oncology
Medicare Parts B & C$47,467 $47,588 $95,517 $94,969 
Commercial49,187 46,212 95,887 91,144 
International46,722 35,586 91,255 72,854 
Other24,282 27,788 47,725 53,639 
Total Precision Oncology167,658 157,174 330,384 312,606 
COVID-19 Testing$— $2,132 $— $5,955 
Total$699,264 $622,093 $1,336,788 $1,224,543 
v3.24.2
MARKETABLE SECURITIES (Tables)
 6 Months Ended
Jun. 30, 2024
Cash and Cash Equivalents [Abstract]  
Cash, Cash Equivalents and Investments
The following table sets forth the Company’s cash, cash equivalents, and marketable securities at June 30, 2024 and December 31, 2023:
(In thousands)June 30, 2024December 31, 2023
Cash and cash equivalents
Cash and money market$519,836 $530,100 
Cash equivalents10,344 75,278 
Total cash and cash equivalents530,180 605,378 
Marketable securities
Available-for-sale debt securities$414,271 $168,425 
Equity securities2,331 3,841 
Total marketable securities416,602 172,266 
Total cash, cash equivalents and marketable securities$946,782 $777,644 
Schedule of available-for-sale securities
Available-for-sale debt securities, including the classification within the condensed consolidated balance sheet at June 30, 2024, consisted of the following:
(In thousands)Amortized CostGains in Accumulated Other Comprehensive Income (Loss) (1)Losses in Accumulated Other Comprehensive Income (Loss) (1)Estimated Fair Value
Cash equivalents
U.S. government agency securities$10,344 $— $— $10,344 
Total cash equivalents10,344 — — 10,344 
Marketable securities
Corporate bonds$203,728 $160 $(600)$203,288 
U.S. government agency securities118,753 3 (130)118,626 
Asset backed securities87,718 21 (325)87,414 
Commercial paper4,943 — — 4,943 
Total marketable securities415,142 184 (1,055)414,271 
Total available-for-sale securities$425,486 $184 $(1,055)$424,615 
______________
(1)There was no tax impact from the gains and losses in accumulated other comprehensive income (loss) (“AOCI”).
Available-for-sale debt securities, including the classification within the condensed consolidated balance sheet at December 31, 2023, consisted of the following:
(In thousands)Amortized CostGains in Accumulated Other Comprehensive Income (Loss) (1) Losses in Accumulated Other Comprehensive Income (Loss) (1)Estimated Fair Value
Cash equivalents
Commercial paper$72,243 $— $— $72,243 
U.S. government agency securities3,035 — — 3,035 
Total cash equivalents75,278 — — 75,278 
Marketable securities
U.S. government agency securities$56,594 $166 $(44)$56,716 
Corporate bonds55,712 175 (59)55,828 
Asset backed securities35,081 65 (249)34,897 
Commercial paper
20,984 — — 20,984 
Total marketable securities168,371 406 (352)168,425 
Total available-for-sale securities$243,649 $406 $(352)$243,703 
______________
(1)There was no tax impact from the gains and losses in AOCI.
Schedule of contractual maturities of available-for-sale investments
The following table summarizes contractual underlying maturities of the Company’s available-for-sale debt securities at June 30, 2024:
Due one year or lessDue after one year through five years
(In thousands)CostFair ValueCostFair Value
Cash equivalents
U.S. government agency securities$10,344 $10,344 $— $— 
Total cash equivalents10,344 10,344 — — 
Marketable securities
U.S. government agency securities$108,950 $108,844 $9,803 $9,782 
Corporate bonds46,393 46,288 157,335 157,000 
Asset backed securities5,901 5,892 81,817 81,522 
Commercial paper
4,943 4,943 — — 
Total marketable securities166,187 165,967 248,955 248,304 
Total available-for-sale securities$176,531 $176,311 $248,955 $248,304 
Schedule of gross unrealized losses and fair values of investments in an unrealized loss position
The following table summarizes the gross unrealized losses and fair values of available-for-sale debt securities in an unrealized loss position as of June 30, 2024 aggregated by investment category and length of time those individual securities have been in a continuous unrealized loss position:
Less than one yearOne year or greaterTotal
(In thousands)Fair ValueGross Unrealized LossFair ValueGross Unrealized LossFair ValueGross Unrealized Loss
Marketable securities
Corporate bonds$129,953 $(578)$4,720 $(22)$134,673 $(600)
U.S. government agency securities108,835 (108)3,913 (22)112,748 (130)
Asset backed securities53,722 (211)6,532 (114)60,254 (325)
Total available-for-sale securities$292,510 $(897)$15,165 $(158)$307,675 $(1,055)
v3.24.2
INVENTORY (Tables)
 6 Months Ended
Jun. 30, 2024
Inventory Disclosure [Abstract]  
Schedule of inventory
Inventory consisted of the following:
(In thousands)June 30, 2024December 31, 2023
Raw materials$52,363 $58,593 
Semi-finished and finished goods75,010 68,882 
Total inventory$127,373 $127,475 
v3.24.2
PROPERTY, PLANT AND EQUIPMENT (Tables)
 6 Months Ended
Jun. 30, 2024
Property, Plant and Equipment [Abstract]  
Schedule of property, plant and equipment, net
The carrying value and estimated useful lives of property, plant and equipment are as follows:
(In thousands)Estimated Useful LifeJune 30, 2024December 31, 2023
Property, plant and equipment
Landn/a$4,716 $4,716 
Leasehold and building improvements(1)228,513 214,562 
Land improvements15 years6,747 6,729 
Buildings
30 - 40 years
290,777 290,777 
Computer equipment and computer software3 years198,247 168,131 
Machinery and equipment
3 - 10 years
308,052 290,294 
Furniture and fixtures
3 - 10 years
36,278 35,756 
Assets under constructionn/a100,653 104,592 
Property, plant and equipment, at cost1,173,983 1,115,557 
Accumulated depreciation(470,900)(417,203)
Property, plant and equipment, net$703,083 $698,354 
______________
(1)Lesser of remaining lease term, building life, or estimated useful life.
v3.24.2
INTANGIBLE ASSETS AND GOODWILL (Tables)
 6 Months Ended
Jun. 30, 2024
Goodwill and Intangible Assets Disclosure [Abstract]  
Schedule of net-book value and estimated remaining life and finite lived intangible assets
The following table summarizes the net-book-value and estimated remaining life of the Company’s intangible assets as of June 30, 2024:
(In thousands)Weighted Average Remaining Life (Years)CostAccumulated Amortization
Net Balance at June 30, 2024
Finite-lived intangible assets
Trade name11.2$104,000 $(31,528)$72,472 
Customer relationships6.54,000 (1,111)2,889 
Patents and licenses5.911,542 (10,324)1,218 
Acquired developed technology (1)6.8887,352 (370,453)516,899 
Total finite-lived intangible assets1,006,894 (413,416)593,478 
In-process research and developmentn/a1,250,000 — 1,250,000 
Total intangible assets$2,256,894 $(413,416)$1,843,478 
The following table summarizes the net-book-value and estimated remaining life of the Company’s intangible assets as of December 31, 2023:
(In thousands)Weighted Average Remaining Life (Years)CostAccumulated Amortization
Net balance at December 31, 2023
Finite-lived intangible assets
Trade name11.6$104,000 $(27,903)$76,097 
Customer relationships7.04,000 (889)3,111 
Patents and licenses4.511,542 (9,600)1,942 
Acquired developed technology (1)7.3887,789 (328,543)559,246 
Total finite-lived intangible assets1,007,331 (366,935)640,396 
In-process research and developmentn/a1,250,000 — 1,250,000 
Total intangible assets$2,257,331 $(366,935)$1,890,396 
______________
(1)The gross carrying amount includes an insignificant foreign currency translation adjustment related to the intangible asset acquired as a result of the acquisition of OmicEra Diagnostics GmbH (“OmicEra”).
Schedule of estimated future amortization expense, intangible assets
As of June 30, 2024 the estimated future amortization expense associated with the Company’s finite-lived intangible assets for each of the five succeeding fiscal years is as follows:
(In thousands)
2024 (remaining six months)$46,288 
202591,860 
202690,800 
202790,800 
202890,800 
Thereafter182,930 
$593,478 
Schedule of carrying amount of goodwill
The change in the carrying amount of goodwill for the periods ended June 30, 2024 and December 31, 2023 is as follows:
(In thousands)
Balance, January 1, 2023
$2,346,040 
Resolution Bioscience acquisition
20,692 
Effects of changes in foreign currency exchange rates (1)388 
Balance, December 31, 2023
2,367,120 
Resolution Bioscience acquisition adjustment
205 
Effects of changes in foreign currency exchange rates (1)(353)
Balance June 30, 2024
$2,366,972 
______________
(1)Represents the impact of foreign currency translation related to the goodwill acquired as a result of the acquisition of OmicEra.
v3.24.2
FAIR VALUE MEASUREMENTS (Tables)
 6 Months Ended
Jun. 30, 2024
Fair Value Disclosures [Abstract]  
Schedule of fair value measurements along with the level within the fair value hierarchy in which the fair value measurements fall
The following table presents the Company’s fair value measurements as of June 30, 2024 along with the level within the fair value hierarchy in which the fair value measurements, in their entirety, fall.
(In thousands)Fair Value at June 30, 2024Quoted Prices in Active Markets for Identical Assets (Level 1)Significant Other Observable Inputs (Level 2)Significant Unobservable Inputs (Level 3)
Cash, cash equivalents, and restricted cash
Cash and money market$519,836 $519,836 $— $— 
U.S. government agency securities10,344 — 10,344 — 
Restricted cash (1)
5,837 5,837 — — 
Marketable securities
Corporate bonds$203,288 $— $203,288 $— 
U.S. government agency securities118,626 — 118,626 — 
Asset backed securities87,414 — 87,414 — 
Commercial paper4,943 — 4,943 — 
Equity securities2,331 2,331 — — 
Non-marketable securities$1,057 $— $— $1,057 
Liabilities
Contingent consideration$(277,921)$— $— $(277,921)
Total$675,755 $528,004 $424,615 $(276,864)
The following table presents the Company’s fair value measurements as of December 31, 2023 along with the level within the fair value hierarchy in which the fair value measurements, in their entirety, fall.
(In thousands)Fair Value at December 31, 2023Quoted Prices in Active Markets for Identical Assets (Level 1)Significant Other Observable Inputs (Level 2)Significant Unobservable Inputs (Level 3)
Cash, cash equivalents and restricted cash
Cash and money market$530,100 $530,100 $— $— 
Commercial paper72,243 — 72,243 — 
Restricted cash (1)
4,297 4,297 — — 
U.S. government agency securities3,035 — 3,035 — 
Marketable securities
U.S. government agency securities$56,716 $— $56,716 $— 
Corporate bonds55,828 — 55,828 — 
Asset backed securities34,897 — 34,897 — 
Commercial paper20,984 — 20,984 — 
Equity securities3,841 3,841 — — 
Non-marketable securities$7,650 $— $— $7,650 
Liabilities
Contingent consideration$(288,657)$— $— $(288,657)
Total$500,934 $538,238 $243,703 $(281,007)
_________________________________
(1)Restricted cash primarily represents cash held by a third-party financial institution as part of a cash collateral agreement related to the Company’s credit card program. The restrictions will lapse upon the termination of the agreements or the removal of the cash collateral requirement by the third-parties.
Schedule of fair value of contingent consideration
The following table provides a reconciliation of the beginning and ending balances of contingent consideration:
(In thousands)Contingent Consideration
Beginning balance, January 1, 2024
$288,657 
Changes in fair value (1)(7,636)
Payments (2)
(3,100)
Ending balance, June 30, 2024
$277,921 
______________
(1)The change in fair value of the contingent consideration liability was an increase of $4.2 million and a reduction of $4.7 million for the three and six months ended June 30, 2023, respectively, which is included in general and administrative expenses in the condensed consolidated statement of operations.
(2)Payment was made in the second quarter of 2024 to settle the contingent consideration liability previously recorded related to the Company’s acquisition of OmicEra.
Securities Owned Not Readily Marketable
The Company has elected the fair value option under the income approach to measure certain Level 3 non-marketable securities. Gains and losses recorded on non-marketable securities are included in investment income, net in the condensed consolidated statement of operations. The following table provides a reconciliation of the beginning and ending balances of non-marketable securities valued using the fair value option:
(In thousands)Non-Marketable Securities
Beginning balance, January 1, 2024
$7,650 
Changes in fair value(343)
Settlement of non-marketable securities(6,250)
Ending balance, June 30, 2024
$1,057 
Other Investments Not Readily Marketable
Non-Marketable Equity Investments
Non-marketable equity securities without readily determinable fair values, which are classified as a component of other long-term assets, net, had the following cumulative upward and downward adjustments and aggregate carrying amounts:
(In thousands)
June 30, 2024June 30, 2023
Cumulative upward adjustments (1)
$5,102 $779 
Cumulative downward adjustments and impairments (2)
15,071 12,528 
Aggregate carrying value (3)
52,227 34,197 
_________________________________
(1)    There were no material upward adjustments recorded on non-marketable equity securities held for the three and six months ended June 30, 2024 and 2023.
(2)    There were no material downward adjustments or impairments recorded on non-marketable equity securities held for the three and six months ended June 30, 2024 and 2023, respectively.
(3)    The aggregate carrying value of non-marketable equity securities was $46.0 million as of December 31, 2023.
v3.24.2
CONVERTIBLE NOTES (Tables)
 6 Months Ended
Jun. 30, 2024
CONVERTIBLE NOTES [Abstract]  
Schedule of convertible note obligations included in the condensed consolidated balance sheets
Convertible note obligations included in the condensed consolidated balance sheet consisted of the following as of June 30, 2024:
Fair Value (1)
(In thousands)Principal AmountUnamortized Debt Discount and Issuance CostsNet Carrying AmountAmountLeveling
2031 Convertible Notes - 1.750%
$620,709 $(14,633)$606,076 $510,335 2
2030 Convertible Notes - 2.000%
572,993 (3,998)568,995 513,373 2
2028 Convertible Notes - 0.375%
589,380 (5,741)583,639 482,702 2
2027 Convertible Notes - 0.375%
563,822 (4,584)559,238 494,872 2
2025 Convertible Notes - 1.000% (2)
249,172 (249)248,923 242,943 2
Convertible note obligations included in the condensed consolidated balance sheet consisted of the following as of December 31, 2023:
Fair Value (1)
(In thousands)Principal AmountUnamortized Debt Discount and Issuance CostsNet Carrying AmountAmountLeveling
2030 Convertible Notes - 2.000%
$572,993 $(4,349)$568,644 $684,475 2
2028 Convertible Notes - 0.375%
949,042 (10,499)938,543 887,354 2
2027 Convertible Notes - 0.375%
563,822 (5,429)558,393 549,839 2
2025 Convertible Notes - 1.000%
249,172 (476)248,696 293,300 2
______________
(1)The fair values are based on observable market prices for this debt, which is traded in less active markets and therefore is classified as a Level 2 fair value measurement.
(2)The Company’s convertible notes due in 2025 (the “2025 Notes”) mature on January 15, 2025 and are included in convertible notes, net, current portion on the condensed consolidated balance sheet as of June 30, 2024. The 2025 Notes were included in convertible notes, net, less current portion as of December 31, 2023.
Schedule of allocation of transaction costs related to convertible debt The following table summarizes the original issuance costs at the time of issuance for each set of Notes:
(In thousands)
2031 Convertible Notes
$6,820 
2030 Convertible Notes4,938 
2028 Convertible Notes24,453 
2027 Convertible Notes14,285 
2025 Convertible Notes17,646 
Schedule of interest expense
Interest expense on the Notes includes the following:
Three Months Ended June 30,Six Months Ended June 30,
(In thousands)2024202320242023
Debt issuance costs amortization$1,316 $1,315 $2,631 $2,692 
Debt discount amortization264 25 289 56 
Gain on settlements of convertible notes(10,254)— (10,254)(10,324)
Coupon interest expense6,863 4,906 11,770 8,260 
Total interest expense (income) on convertible notes$(1,811)$6,246 $4,436 $684 
Schedule of effective interest rates related to convertible debt
The following table summarizes the effective interest rates of the Notes:
Three Months Ended June 30,Six Months Ended June 30,
2024202320242023
2031 Convertible Notes
2.06 %— %2.06 %— %
2030 Convertible Notes2.12 %2.12 %2.10 %2.10 %
2028 Convertible Notes0.64 %0.64 %0.63 %0.63 %
2027 Convertible Notes0.67 %0.67 %0.67 %0.67 %
2025 Convertible Notes1.18 %1.18 %1.17 %1.18 %
v3.24.2
STOCKHOLDERS' EQUITY (Tables)
 6 Months Ended
Jun. 30, 2024
Equity [Abstract]  
Schedule of amounts recognized in accumulated other comprehensive income (loss) (AOCI)
The amounts recognized in AOCI for the six months ended June 30, 2024 were as follows:
(In thousands)Cumulative Translation AdjustmentUnrealized Gain (Loss) on Securities (1)
AOCI
Balance at December 31, 2023$1,374 $54 $1,428 
Other comprehensive loss before reclassifications
(1,446)(984)(2,430)
Amounts reclassified from accumulated other comprehensive income (loss)
— 59 59 
Net current period change in accumulated other comprehensive income (loss)
(1,446)(925)(2,371)
Balance at June 30, 2024$(72)$(871)$(943)
______________
(1)There was no tax impact from the amounts recognized in AOCI for the three and six months ended June 30, 2024.
The amounts recognized in AOCI for the six months ended June 30, 2023 were as follows:
(In thousands)Cumulative Translation AdjustmentUnrealized Gain (Loss) on Securities (1)
AOCI
Balance at December 31, 2022$53 $(5,289)$(5,236)
Other comprehensive income before reclassifications
609 1,051 1,660 
Amounts reclassified from accumulated other comprehensive income (loss)
— 2,853 2,853 
Net current period change in accumulated other comprehensive income (loss)
609 3,904 4,513 
Balance at June 30, 2023$662 $(1,385)$(723)
______________
(1)There was no tax impact from the amounts recognized in AOCI for the six months ended June 30, 2023.
Schedule of amounts reclassified from accumulated other comprehensive income (loss)
Amounts reclassified from AOCI for the six months ended June 30, 2024 and 2023 were as follows:
Affected Line Item in the
Statements of Operations		Six Months Ended June 30,
Details about AOCI Components (In thousands)20242023
Change in value of available-for-sale investments
Sales and maturities of available-for-sale investments
Investment income, net
$59 $2,853 
Total reclassifications$59 $2,853 
v3.24.2
STOCK-BASED COMPENSATION (Tables)
 6 Months Ended
Jun. 30, 2024
Share-Based Payment Arrangement [Abstract]  
Summary of Stock Option Activity Under the Stock Plans
A summary of stock option activity under the Stock Plans is as follows:
Option SharesWeighted Average Exercise PriceWeighted Average Remaining Contractual Term (Years)Aggregate Intrinsic Value (1)
(Aggregate intrinsic value in thousands)
Outstanding, January 1, 20241,286,173 $47.67 3.8
Exercised(141,503)15.44 
Forfeited(17,164)94.85 
Outstanding, June 30, 20241,127,506 $51.00 3.6$11,834 
Vested and expected to vest, June 30, 2024
1,127,506 $51.00 3.6$11,834 
Exercisable, June 30, 20241,127,506 $51.00 3.6$11,834 
______________
(1)The total intrinsic value of options exercised, net of shares withheld for taxes, during the six months ended June 30, 2024 and 2023 was $3.3 million and $7.0 million, respectively, determined as of the date of exercise.
Summary of Restricted Stock and Restricted Stock Unit Activity Under the Stock Plans
A summary of restricted stock and RSU activity during the six months ended June 30, 2024 is as follows:
Restricted SharesWeighted Average Grant Date Fair Value (1)
Outstanding, January 1, 20246,272,763 $73.39 
Granted3,937,097 57.38 
Released (2)(1,924,514)79.93 
Forfeited(504,123)64.23 
Outstanding, June 30, 20247,781,223 $63.97 
______________
(1)The weighted average grant date fair value of the RSUs granted during the six months ended June 30, 2023 was $60.94.
(2)The fair value of RSUs vested and converted to shares of the Company’s common stock was $153.4 million and $130.5 million during the six months ended June 30, 2024 and 2023, respectively.
Share-based Payment Arrangement, Performance Shares, Activity
A summary of PSU activity during the six months ended June 30, 2024 is as follows:
Performance Share Units (1)Weighted Average Grant Date Fair Value (2)
Outstanding, January 1, 20241,597,801 $92.73 
Granted913,533 63.68 
Released (3)(70,662)140.20 
Forfeited(336,852)106.06 
Outstanding, June 30, 20242,103,820 $74.25 
______________
(1)The PSUs listed above assumes attainment of maximum payout rates as set forth in the performance criteria. Applying actual or expected payout rates, the number of outstanding PSUs as of June 30, 2024 was 1,037,206.
(2)The weighted average grant date fair value of the PSUs granted during the six months ended June 30, 2023 was $79.17.
(3)The fair value of PSUs vested and converted to shares of the Company’s common stock was $9.9 million and $1.0 million for the six months ended June 30, 2024 and 2023, respectively.
Schedule of Share-Based Compensation, Employee Stock Purchase Plan, Activity
The fair value of shares purchased during the three and six months ended June 30, 2024 and 2023 under the ESPP is based on the assumptions in the following table:
Three Months Ended June 30,Six Months Ended June 30,
2024202320242023
ESPP Shares
Risk-free interest rates
4.71% - 5.30%
4.68%
4.71% - 5.30%
4.68%
Expected term (in years)1.171.251.171.25
Expected volatility
55.67% - 63.13%
67.30%
55.67% - 63.13%
67.30%
Dividend yield
—%
—%—%—%
v3.24.2
COMMITMENTS AND CONTINGENCIES (Tables)
 6 Months Ended
Jun. 30, 2024
Commitments and Contingencies Disclosure [Abstract]  
Supplemental disclosure of cash flow information related to our operating leases
Supplemental disclosure of cash flow information related to the Company’s cash and non-cash activities with its leases are as follows:
Six Months Ended June 30,
(In thousands)20242023
Cash paid for amounts included in the measurement of lease liabilities:
Operating cash flows from operating leases$19,188$19,093
Operating cash flows from finance leases612342
Finance cash flows from finance leases3,0251,561
Non-cash investing and financing activities:
Right-of-use assets obtained in exchange for new operating lease liabilities (1)$18,925$(5,375)
Right-of-use assets obtained in exchange for new finance lease liabilities13,7172,670
Weighted-average remaining lease term - operating leases (in years)7.737.20
Weighted-average remaining lease term - finance leases (in years)3.213.04
Weighted-average discount rate - operating leases6.55 %6.41 %
Weighted-average discount rate - finance leases6.78 %7.03 %
v3.24.2
SEGMENT INFORMATION (Tables)
 6 Months Ended
Jun. 30, 2024
Segment Reporting [Abstract]  
Revenue from external customers by geographic areas
The following table summarizes total revenue from customers by geographic region. Product revenues are attributed to countries based on ship-to location.
Three Months Ended June 30,Six Months Ended June 30,
(In thousands)2024202320242023
United States$652,542 $586,507 $1,245,533 $1,151,689 
Outside of United States46,722 35,586 91,255 72,854 
Total revenues$699,264 $622,093 $1,336,788 $1,224,543 
v3.24.2
SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES - Reconciliation of the Numerator and Denominator Used to Calculate Basic EPS and Diluted EPS (Details) - $ / shares
shares in Thousands
 3 Months Ended 6 Months Ended
Jun. 30, 2024
Jun. 30, 2023
Jun. 30, 2024
Jun. 30, 2023
Earnings Per Share, Diluted, by Common Class, Including Two Class Method [Line Items]        
Weighted average common shares outstanding—basic (in shares) 184,313 180,204 183,332 179,393
Increase (decrease) in net loss per share (in usd per share) $ (0.09) $ (0.45) $ (0.69) $ (0.87)
v3.24.2
SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES - Net Loss Per Share (Details) - shares
shares in Thousands
 6 Months Ended
Jun. 30, 2024
Jun. 30, 2023
Common shares not included in the computation of diluted net loss per share    
Potentially issuable common shares not included in the computation of diluted net loss per share because they would have an anti-dilutive effect 37,539 32,756
Shares issuable upon exercise of stock options    
Common shares not included in the computation of diluted net loss per share    
Potentially issuable common shares not included in the computation of diluted net loss per share because they would have an anti-dilutive effect 1,128 1,366
Shares issuable upon the release of restricted stock awards    
Common shares not included in the computation of diluted net loss per share    
Potentially issuable common shares not included in the computation of diluted net loss per share because they would have an anti-dilutive effect 7,781 6,590
Shares issuable upon the release of performance share units    
Common shares not included in the computation of diluted net loss per share    
Potentially issuable common shares not included in the computation of diluted net loss per share because they would have an anti-dilutive effect 2,104 1,569
Shares issuable upon conversion of convertible notes    
Common shares not included in the computation of diluted net loss per share    
Potentially issuable common shares not included in the computation of diluted net loss per share because they would have an anti-dilutive effect 26,526 23,231
v3.24.2
REVENUE - Schedule of Disaggregation of Revenue (Details) - USD ($)
$ in Thousands
 3 Months Ended 6 Months Ended
Jun. 30, 2024
Jun. 30, 2023
Jun. 30, 2024
Jun. 30, 2023
Disaggregation of Revenue [Line Items]        
Revenue recognized $ 699,264 $ 622,093 $ 1,336,788 $ 1,224,543
Screening        
Disaggregation of Revenue [Line Items]        
Revenue recognized 531,606 462,787 1,006,404 905,982
Screening | Medicare Parts B & C        
Disaggregation of Revenue [Line Items]        
Revenue recognized 195,337 176,016 369,127 347,746
Screening | Commercial        
Disaggregation of Revenue [Line Items]        
Revenue recognized 283,729 245,748 537,872 478,781
Screening | Other        
Disaggregation of Revenue [Line Items]        
Revenue recognized 52,540 41,023 99,405 79,455
Precision Oncology        
Disaggregation of Revenue [Line Items]        
Revenue recognized 167,658 157,174 330,384 312,606
Precision Oncology | Medicare Parts B & C        
Disaggregation of Revenue [Line Items]        
Revenue recognized 47,467 47,588 95,517 94,969
Precision Oncology | Commercial        
Disaggregation of Revenue [Line Items]        
Revenue recognized 49,187 46,212 95,887 91,144
Precision Oncology | International        
Disaggregation of Revenue [Line Items]        
Revenue recognized 46,722 35,586 91,255 72,854
Precision Oncology | Other        
Disaggregation of Revenue [Line Items]        
Revenue recognized 24,282 27,788 47,725 53,639
COVID-19 Testing        
Disaggregation of Revenue [Line Items]        
Revenue recognized $ 0 $ 2,132 $ 0 $ 5,955
v3.24.2
REVENUE - Narrative (Details)
 3 Months Ended 6 Months Ended
Jun. 30, 2024
Jun. 30, 2023
Jun. 30, 2024
Jun. 30, 2023
Disaggregation of Revenue [Line Items]        
Contract with Customer, Liability, Cumulative Catch-up Adjustment to Revenue, Change in Estimate of Transaction Price as a Percentage of Revenue     (1.00%) 2.00%
Variable consideration        
Disaggregation of Revenue [Line Items]        
Contract with Customer, Liability, Cumulative Catch-up Adjustment to Revenue, Change in Estimate of Transaction Price as a Percentage of Revenue (1.00%) 2.00%    
v3.24.2
MARKETABLE SECURITIES - Schedule of Cash and Cash Equivalents (Details) - USD ($)
$ in Thousands
Jun. 30, 2024
Dec. 31, 2023
Jun. 30, 2023
Marketable securities      
Cash and money market $ 519,836 $ 530,100  
Cash equivalents 10,344 75,278  
Total cash, cash equivalents and restricted cash 530,180 605,378 $ 604,363
Estimated Fair Value 424,615 243,703  
Equity securities 2,331 3,841  
Marketable securities 416,602 172,266  
Total cash, cash equivalents and marketable securities 946,782 777,644  
Marketable securities      
Marketable securities      
Estimated Fair Value 414,271 168,425  
Available-for-sale debt securities $ 414,271 $ 168,425  
v3.24.2
MARKETABLE SECURITIES - Schedule of Available For Sale Securities (Details) - USD ($)
$ in Thousands
Jun. 30, 2024
Dec. 31, 2023
Available-for-sale securities    
Amortized Cost $ 425,486 $ 243,649
Gains in Accumulated Other Comprehensive Income (Loss) 184 406
Losses in Accumulated Other Comprehensive Income (Loss) (1,055) (352)
Estimated Fair Value 424,615 243,703
Cash equivalents    
Available-for-sale securities    
Amortized Cost 10,344 75,278
Gains in Accumulated Other Comprehensive Income (Loss) 0 0
Losses in Accumulated Other Comprehensive Income (Loss) 0 0
Estimated Fair Value 10,344 75,278
Marketable securities    
Available-for-sale securities    
Amortized Cost 415,142 168,371
Gains in Accumulated Other Comprehensive Income (Loss) 184 406
Losses in Accumulated Other Comprehensive Income (Loss) (1,055) (352)
Estimated Fair Value 414,271 168,425
Commercial paper | Cash equivalents    
Available-for-sale securities    
Amortized Cost   72,243
Gains in Accumulated Other Comprehensive Income (Loss)   0
Losses in Accumulated Other Comprehensive Income (Loss)   0
Estimated Fair Value   72,243
Commercial paper | Marketable securities    
Available-for-sale securities    
Amortized Cost 4,943 20,984
Gains in Accumulated Other Comprehensive Income (Loss) 0 0
Losses in Accumulated Other Comprehensive Income (Loss) 0 0
Estimated Fair Value 4,943 20,984
U.S. government agency securities | Cash equivalents    
Available-for-sale securities    
Amortized Cost 10,344 3,035
Gains in Accumulated Other Comprehensive Income (Loss) 0 0
Losses in Accumulated Other Comprehensive Income (Loss) 0 0
Estimated Fair Value 10,344 3,035
U.S. government agency securities | Marketable securities    
Available-for-sale securities    
Amortized Cost 118,753 56,594
Gains in Accumulated Other Comprehensive Income (Loss) 3 166
Losses in Accumulated Other Comprehensive Income (Loss) (130) (44)
Estimated Fair Value 118,626 56,716
Corporate bonds | Marketable securities    
Available-for-sale securities    
Amortized Cost 203,728 55,712
Gains in Accumulated Other Comprehensive Income (Loss) 160 175
Losses in Accumulated Other Comprehensive Income (Loss) (600) (59)
Estimated Fair Value 203,288 55,828
Asset backed securities | Marketable securities    
Available-for-sale securities    
Amortized Cost 87,718 35,081
Gains in Accumulated Other Comprehensive Income (Loss) 21 65
Losses in Accumulated Other Comprehensive Income (Loss) (325) (249)
Estimated Fair Value $ 87,414 $ 34,897
v3.24.2
MARKETABLE SECURITIES - Schedule of Underlying Maturities of AFS Securities (Details) - USD ($)
$ in Thousands
Jun. 30, 2024
Dec. 31, 2023
Available-for-sale securities    
Due in one year or less, Cost $ 176,531  
Due in one year or less, Fair Value 176,311  
Due after one year through five years, Cost 248,955  
Due after one year through five years, Fair Value 248,304  
Debt Securities, Available-for-Sale, Amortized Cost, Excluding Accrued Interest, before Allowance for Credit Loss 425,486 $ 243,649
Gains in Accumulated Other Comprehensive Income (Loss) 184 406
Losses in Accumulated Other Comprehensive Income (Loss) (1,055) (352)
Estimated Fair Value 424,615 243,703
Cash equivalents    
Available-for-sale securities    
Due in one year or less, Cost 10,344  
Due in one year or less, Fair Value 10,344  
Due after one year through five years, Cost 0  
Due after one year through five years, Fair Value 0  
Debt Securities, Available-for-Sale, Amortized Cost, Excluding Accrued Interest, before Allowance for Credit Loss 10,344 75,278
Gains in Accumulated Other Comprehensive Income (Loss) 0 0
Losses in Accumulated Other Comprehensive Income (Loss) 0 0
Estimated Fair Value 10,344 75,278
Cash equivalents | Commercial paper    
Available-for-sale securities    
Debt Securities, Available-for-Sale, Amortized Cost, Excluding Accrued Interest, before Allowance for Credit Loss   72,243
Gains in Accumulated Other Comprehensive Income (Loss)   0
Losses in Accumulated Other Comprehensive Income (Loss)   0
Estimated Fair Value   72,243
Cash equivalents | U.S. government agency securities    
Available-for-sale securities    
Due in one year or less, Cost 10,344  
Due in one year or less, Fair Value 10,344  
Due after one year through five years, Cost 0  
Due after one year through five years, Fair Value 0  
Debt Securities, Available-for-Sale, Amortized Cost, Excluding Accrued Interest, before Allowance for Credit Loss 10,344 3,035
Gains in Accumulated Other Comprehensive Income (Loss) 0 0
Losses in Accumulated Other Comprehensive Income (Loss) 0 0
Estimated Fair Value 10,344 3,035
Marketable securities    
Available-for-sale securities    
Due in one year or less, Cost 166,187  
Due in one year or less, Fair Value 165,967  
Due after one year through five years, Cost 248,955  
Due after one year through five years, Fair Value 248,304  
Debt Securities, Available-for-Sale, Amortized Cost, Excluding Accrued Interest, before Allowance for Credit Loss 415,142 168,371
Gains in Accumulated Other Comprehensive Income (Loss) 184 406
Losses in Accumulated Other Comprehensive Income (Loss) (1,055) (352)
Estimated Fair Value 414,271 168,425
Marketable securities | Commercial paper    
Available-for-sale securities    
Due in one year or less, Cost 4,943  
Due in one year or less, Fair Value 4,943  
Due after one year through five years, Cost 0  
Due after one year through five years, Fair Value 0  
Debt Securities, Available-for-Sale, Amortized Cost, Excluding Accrued Interest, before Allowance for Credit Loss 4,943 20,984
Gains in Accumulated Other Comprehensive Income (Loss) 0 0
Losses in Accumulated Other Comprehensive Income (Loss) 0 0
Estimated Fair Value 4,943 20,984
Marketable securities | U.S. government agency securities    
Available-for-sale securities    
Due in one year or less, Cost 108,950  
Due in one year or less, Fair Value 108,844  
Due after one year through five years, Cost 9,803  
Due after one year through five years, Fair Value 9,782  
Debt Securities, Available-for-Sale, Amortized Cost, Excluding Accrued Interest, before Allowance for Credit Loss 118,753 56,594
Gains in Accumulated Other Comprehensive Income (Loss) 3 166
Losses in Accumulated Other Comprehensive Income (Loss) (130) (44)
Estimated Fair Value 118,626 56,716
Marketable securities | Corporate bonds    
Available-for-sale securities    
Due in one year or less, Cost 46,393  
Due in one year or less, Fair Value 46,288  
Due after one year through five years, Cost 157,335  
Due after one year through five years, Fair Value 157,000  
Debt Securities, Available-for-Sale, Amortized Cost, Excluding Accrued Interest, before Allowance for Credit Loss 203,728 55,712
Gains in Accumulated Other Comprehensive Income (Loss) 160 175
Losses in Accumulated Other Comprehensive Income (Loss) (600) (59)
Estimated Fair Value 203,288 55,828
Marketable securities | Asset backed securities    
Available-for-sale securities    
Due in one year or less, Cost 5,901  
Due in one year or less, Fair Value 5,892  
Due after one year through five years, Cost 81,817  
Due after one year through five years, Fair Value 81,522  
Debt Securities, Available-for-Sale, Amortized Cost, Excluding Accrued Interest, before Allowance for Credit Loss 87,718 35,081
Gains in Accumulated Other Comprehensive Income (Loss) 21 65
Losses in Accumulated Other Comprehensive Income (Loss) (325) (249)
Estimated Fair Value $ 87,414 $ 34,897
v3.24.2
MARKETABLE SECURITIES - Schedule of Gross Unrealized Losses and Fair Values of Investments in an Unrealized Loss Position (Details)
$ in Thousands
Jun. 30, 2024
USD ($)
Marketable securities  
Total fair value of available-for-sale securities in a continuous unrealized loss position for less than twelve months $ 292,510
Total gross unrealized losses of available-for-sale securities in a continuous unrealized loss position for less than twelve months (897)
Debt securities, available-for-sale, continuous unrealized loss position, 12 months of longer 15,165
Debt securities, available-for-sale, continuous unrealized loss position, 12 months of longer, accumulated loss (158)
Total fair value of available-for-sale securities in a continuous unrealized loss position 307,675
Total gross unrealized losses of available-for-sale securities in a continuous unrealized loss position (1,055)
Corporate bonds | Marketable securities  
Marketable securities  
Total fair value of available-for-sale securities in a continuous unrealized loss position for less than twelve months 129,953
Total gross unrealized losses of available-for-sale securities in a continuous unrealized loss position for less than twelve months (578)
Debt securities, available-for-sale, continuous unrealized loss position, 12 months of longer 4,720
Debt securities, available-for-sale, continuous unrealized loss position, 12 months of longer, accumulated loss (22)
Total fair value of available-for-sale securities in a continuous unrealized loss position 134,673
Total gross unrealized losses of available-for-sale securities in a continuous unrealized loss position (600)
Asset backed securities | Marketable securities  
Marketable securities  
Total fair value of available-for-sale securities in a continuous unrealized loss position for less than twelve months 53,722
Total gross unrealized losses of available-for-sale securities in a continuous unrealized loss position for less than twelve months (211)
Debt securities, available-for-sale, continuous unrealized loss position, 12 months of longer 6,532
Debt securities, available-for-sale, continuous unrealized loss position, 12 months of longer, accumulated loss (114)
Total fair value of available-for-sale securities in a continuous unrealized loss position 60,254
Total gross unrealized losses of available-for-sale securities in a continuous unrealized loss position (325)
U.S. government agency securities | Marketable securities  
Marketable securities  
Total fair value of available-for-sale securities in a continuous unrealized loss position for less than twelve months 108,835
Total gross unrealized losses of available-for-sale securities in a continuous unrealized loss position for less than twelve months (108)
Debt securities, available-for-sale, continuous unrealized loss position, 12 months of longer 3,913
Debt securities, available-for-sale, continuous unrealized loss position, 12 months of longer, accumulated loss (22)
Total fair value of available-for-sale securities in a continuous unrealized loss position 112,748
Total gross unrealized losses of available-for-sale securities in a continuous unrealized loss position $ (130)
v3.24.2
INVENTORY (Details) - USD ($)
$ in Thousands
Jun. 30, 2024
Dec. 31, 2023
Inventory Disclosure [Abstract]    
Raw materials $ 52,363 $ 58,593
Semi-finished and finished goods 75,010 68,882
Total inventory $ 127,373 $ 127,475
v3.24.2
PROPERTY, PLANT AND EQUIPMENT - Schedule of Estimated Useful Lives (Details) - USD ($)
$ in Thousands
Jun. 30, 2024
Dec. 31, 2023
Property, plant and equipment    
Property, plant and equipment, at cost $ 1,173,983 $ 1,115,557
Accumulated depreciation (470,900) (417,203)
Property, plant and equipment, net 703,083 698,354
Land    
Property, plant and equipment    
Property, plant and equipment, at cost 4,716 4,716
Leasehold and building improvements    
Property, plant and equipment    
Property, plant and equipment, at cost $ 228,513 214,562
Land improvements    
Property, plant and equipment    
Estimated Useful Life 15 years  
Property, plant and equipment, at cost $ 6,747 6,729
Buildings    
Property, plant and equipment    
Property, plant and equipment, at cost $ 290,777 290,777
Computer equipment and computer software    
Property, plant and equipment    
Estimated Useful Life 3 years  
Property, plant and equipment, at cost $ 198,247 168,131
Machinery and equipment    
Property, plant and equipment    
Property, plant and equipment, at cost 308,052 290,294
Furniture and fixtures    
Property, plant and equipment    
Property, plant and equipment, at cost 36,278 35,756
Assets under construction    
Property, plant and equipment    
Property, plant and equipment, at cost $ 100,653 $ 104,592
Minimum | Buildings    
Property, plant and equipment    
Estimated Useful Life 30 years  
Minimum | Machinery and equipment    
Property, plant and equipment    
Estimated Useful Life 3 years  
Minimum | Furniture and fixtures    
Property, plant and equipment    
Estimated Useful Life 3 years  
Maximum | Buildings    
Property, plant and equipment    
Estimated Useful Life 40 years  
Maximum | Machinery and equipment    
Property, plant and equipment    
Estimated Useful Life 10 years  
Maximum | Furniture and fixtures    
Property, plant and equipment    
Estimated Useful Life 10 years  
v3.24.2
PROPERTY, PLANT AND EQUIPMENT - Narrative (Details) - USD ($)
$ in Thousands
 3 Months Ended 6 Months Ended
Jun. 30, 2024
Jun. 30, 2023
Jun. 30, 2024
Jun. 30, 2023
Property, plant and equipment        
Depreciation $ 29,700 $ 27,500 $ 60,319 $ 54,325
Assets under construction 100,700   100,700  
Buildings        
Property, plant and equipment        
Assets under construction 5,100   5,100  
Machinery and equipment        
Property, plant and equipment        
Assets under construction 62,600   62,600  
Leasehold and building improvements        
Property, plant and equipment        
Assets under construction 8,100   8,100  
Computer software        
Property, plant and equipment        
Assets under construction $ 24,800   $ 24,800  
v3.24.2
INTANGIBLE ASSETS AND GOODWILL - Schedule of Finite Lived Intangible Assets Net Balances and Weighted Average Useful Lives (Details) - USD ($)
$ in Thousands
 3 Months Ended 6 Months Ended
Jun. 30, 2024
Jun. 30, 2023
Jun. 30, 2024
Jun. 30, 2023
Dec. 31, 2023
Finite-Lived Intangible Assets [Line Items]          
Cost $ 1,006,894   $ 1,006,894   $ 1,007,331
Accumulated Amortization (413,416)   (413,416)   (366,935)
Intangibles, net 593,478   593,478   640,396
In-process research and development 1,250,000   1,250,000   1,250,000
Finite-lived and indefinite-lived intangible assets, gross 2,256,894   2,256,894   2,257,331
Finite-lived and indefinite-lived intangible assets, net 1,843,478   1,843,478   $ 1,890,396
Impairment of intangible assets, finite-lived $ 0 $ 0 $ 0 $ 0  
Trade name          
Finite-Lived Intangible Assets [Line Items]          
Weighted-average remaining useful life of finite-lived intangible asset (in years) 11 years 2 months 12 days   11 years 2 months 12 days   11 years 7 months 6 days
Cost $ 104,000   $ 104,000   $ 104,000
Accumulated Amortization (31,528)   (31,528)   (27,903)
Intangibles, net $ 72,472   $ 72,472   $ 76,097
Customer relationships          
Finite-Lived Intangible Assets [Line Items]          
Weighted-average remaining useful life of finite-lived intangible asset (in years) 6 years 6 months   6 years 6 months   7 years
Cost $ 4,000   $ 4,000   $ 4,000
Accumulated Amortization (1,111)   (1,111)   (889)
Intangibles, net $ 2,889   $ 2,889   $ 3,111
Patents and licenses          
Finite-Lived Intangible Assets [Line Items]          
Weighted-average remaining useful life of finite-lived intangible asset (in years) 5 years 10 months 24 days   5 years 10 months 24 days   4 years 6 months
Cost $ 11,542   $ 11,542   $ 11,542
Accumulated Amortization (10,324)   (10,324)   (9,600)
Intangibles, net $ 1,218   $ 1,218   $ 1,942
Developed Technology Rights          
Finite-Lived Intangible Assets [Line Items]          
Weighted-average remaining useful life of finite-lived intangible asset (in years) 6 years 9 months 18 days   6 years 9 months 18 days   7 years 3 months 18 days
Cost $ 887,352   $ 887,352   $ 887,789
Accumulated Amortization (370,453)   (370,453)   (328,543)
Intangibles, net $ 516,899   $ 516,899   $ 559,246
v3.24.2
INTANGIBLE ASSETS AND GOODWILL - Schedule of Future Amortization Expense (Details) - USD ($)
$ in Thousands
Jun. 30, 2024
Dec. 31, 2023
Goodwill and Intangible Assets Disclosure [Abstract]    
2024 $ 46,288  
2025 91,860  
2026 90,800  
2027 90,800  
2028 90,800  
Thereafter 182,930  
Intangibles, net $ 593,478 $ 640,396
v3.24.2
INTANGIBLE ASSETS AND GOODWILL - Schedule of Changes in Goodwill (Details) - USD ($)
$ in Thousands
 6 Months Ended 12 Months Ended
Jun. 30, 2024
Dec. 31, 2023
Recognized Goodwill    
Beginning balance $ 2,367,120 $ 2,346,040
Goodwill, foreign currency translation gain (loss) (353) 388
Ending balance 2,366,972 2,367,120
Resolution Bioscience    
Recognized Goodwill    
Resolution Bioscience acquisition   $ 20,692
Goodwill, Purchase Accounting Adjustments $ 205  
v3.24.2
INTANGIBLE ASSETS AND GOODWILL - Narrative (Details) - USD ($)
 3 Months Ended 6 Months Ended
Jun. 30, 2024
Jun. 30, 2023
Jun. 30, 2024
Jun. 30, 2023
Dec. 31, 2023
Finite-Lived Intangible Assets [Line Items]          
Gross value of intangible asset $ 1,006,894,000   $ 1,006,894,000   $ 1,007,331,000
Finite-lived intangible assets, accumulated amortization 413,416,000   413,416,000   366,935,000
Intangibles, net 593,478,000   593,478,000   640,396,000
Impairment losses 0 $ 0 0 $ 0  
Developed Technology Rights          
Finite-Lived Intangible Assets [Line Items]          
Gross value of intangible asset 887,352,000   887,352,000   887,789,000
Finite-lived intangible assets, accumulated amortization 370,453,000   370,453,000   328,543,000
Intangibles, net $ 516,899,000   $ 516,899,000   $ 559,246,000
v3.24.2
FAIR VALUE MEASUREMENTS - Schedule of Fair Value (Details) - USD ($)
$ in Thousands
Jun. 30, 2024
Dec. 31, 2023
Fair value measurements    
Equity securities $ 2,331 $ 3,841
Non-marketable securities 1,057 7,650
Contingent consideration 277,921 288,657
Contingent consideration (19,000)  
Fair Value, Recurring    
Fair value measurements    
Restricted cash (1) 5,837 4,297
Equity securities 2,331 3,841
Non-marketable securities 1,057 7,650
Contingent consideration   288,657
Contingent consideration (277,921)  
Total 675,755 500,934
Fair Value, Recurring | Corporate bonds    
Fair value measurements    
Estimated Fair Value 203,288 55,828
Fair Value, Recurring | Commercial paper    
Fair value measurements    
Estimated Fair Value 4,943 20,984
Fair Value, Recurring | U.S. government agency securities    
Fair value measurements    
Estimated Fair Value 118,626 56,716
Fair Value, Recurring | Asset backed securities    
Fair value measurements    
Estimated Fair Value 87,414 34,897
Fair Value, Recurring | Cash and money market    
Fair value measurements    
Cash and cash equivalents, fair value 519,836 530,100
Fair Value, Recurring | U.S. government agency securities    
Fair value measurements    
Cash and cash equivalents, fair value 10,344 3,035
Fair Value, Recurring | Commercial paper    
Fair value measurements    
Cash and cash equivalents, fair value   72,243
Quoted Prices in Active Markets for Identical Assets (Level 1) | Fair Value, Recurring    
Fair value measurements    
Restricted cash (1) 5,837 4,297
Equity securities 2,331 3,841
Non-marketable securities 0 0
Contingent consideration   0
Contingent consideration 0  
Total 528,004 538,238
Quoted Prices in Active Markets for Identical Assets (Level 1) | Fair Value, Recurring | Corporate bonds    
Fair value measurements    
Estimated Fair Value 0 0
Quoted Prices in Active Markets for Identical Assets (Level 1) | Fair Value, Recurring | Commercial paper    
Fair value measurements    
Estimated Fair Value 0 0
Quoted Prices in Active Markets for Identical Assets (Level 1) | Fair Value, Recurring | U.S. government agency securities    
Fair value measurements    
Estimated Fair Value 0 0
Quoted Prices in Active Markets for Identical Assets (Level 1) | Fair Value, Recurring | Asset backed securities    
Fair value measurements    
Estimated Fair Value 0 0
Quoted Prices in Active Markets for Identical Assets (Level 1) | Fair Value, Recurring | Cash and money market    
Fair value measurements    
Cash and cash equivalents, fair value 519,836 530,100
Quoted Prices in Active Markets for Identical Assets (Level 1) | Fair Value, Recurring | U.S. government agency securities    
Fair value measurements    
Cash and cash equivalents, fair value 0 0
Quoted Prices in Active Markets for Identical Assets (Level 1) | Fair Value, Recurring | Commercial paper    
Fair value measurements    
Cash and cash equivalents, fair value   0
Significant Other Observable Inputs (Level 2) | Fair Value, Recurring    
Fair value measurements    
Restricted cash (1) 0 0
Equity securities 0 0
Non-marketable securities 0 0
Contingent consideration   0
Contingent consideration 0  
Total 424,615 243,703
Significant Other Observable Inputs (Level 2) | Fair Value, Recurring | Corporate bonds    
Fair value measurements    
Estimated Fair Value 203,288 55,828
Significant Other Observable Inputs (Level 2) | Fair Value, Recurring | Commercial paper    
Fair value measurements    
Estimated Fair Value 4,943 20,984
Significant Other Observable Inputs (Level 2) | Fair Value, Recurring | U.S. government agency securities    
Fair value measurements    
Estimated Fair Value 118,626 56,716
Significant Other Observable Inputs (Level 2) | Fair Value, Recurring | Asset backed securities    
Fair value measurements    
Estimated Fair Value 87,414 34,897
Significant Other Observable Inputs (Level 2) | Fair Value, Recurring | Cash and money market    
Fair value measurements    
Cash and cash equivalents, fair value 0 0
Significant Other Observable Inputs (Level 2) | Fair Value, Recurring | U.S. government agency securities    
Fair value measurements    
Cash and cash equivalents, fair value 10,344 3,035
Significant Other Observable Inputs (Level 2) | Fair Value, Recurring | Commercial paper    
Fair value measurements    
Cash and cash equivalents, fair value   72,243
Significant Unobservable Inputs (Level 3) | Fair Value, Recurring    
Fair value measurements    
Restricted cash (1) 0 0
Equity securities 0 0
Non-marketable securities 1,057 7,650
Contingent consideration   288,657
Contingent consideration (277,921)  
Total (276,864) (281,007)
Significant Unobservable Inputs (Level 3) | Fair Value, Recurring | Corporate bonds    
Fair value measurements    
Estimated Fair Value 0 0
Significant Unobservable Inputs (Level 3) | Fair Value, Recurring | Commercial paper    
Fair value measurements    
Estimated Fair Value 0 0
Significant Unobservable Inputs (Level 3) | Fair Value, Recurring | U.S. government agency securities    
Fair value measurements    
Estimated Fair Value 0 0
Significant Unobservable Inputs (Level 3) | Fair Value, Recurring | Asset backed securities    
Fair value measurements    
Estimated Fair Value 0 0
Significant Unobservable Inputs (Level 3) | Fair Value, Recurring | Cash and money market    
Fair value measurements    
Cash and cash equivalents, fair value 0 0
Significant Unobservable Inputs (Level 3) | Fair Value, Recurring | U.S. government agency securities    
Fair value measurements    
Cash and cash equivalents, fair value $ 0 0
Significant Unobservable Inputs (Level 3) | Fair Value, Recurring | Commercial paper    
Fair value measurements    
Cash and cash equivalents, fair value   $ 0
v3.24.2
FAIR VALUE MEASUREMENTS - Fair Value of Contingent Consideration (Details) - USD ($)
$ in Thousands
 3 Months Ended 6 Months Ended
Jun. 30, 2023
Jun. 30, 2024
Jun. 30, 2023
Fair Value Disclosures [Abstract]      
Beginning balance   $ 288,657  
Ending balance   277,921  
Change in amount of contingent consideration liability $ 4,200 (7,636) $ (4,687)
Payment for Contingent Consideration Liability, Investing Activities   $ 3,100  
v3.24.2
FAIR VALUE MEASUREMENTS - Schedule of Non-marketable Equity Investments (Details) - USD ($)
$ in Thousands
 6 Months Ended
Jun. 30, 2024
Dec. 31, 2023
Jun. 30, 2023
Fair Value Disclosures [Abstract]      
Non-marketable securities $ 1,057 $ 7,650  
Changes in fair value (343)    
Settlement of non-marketable securities (6,250)    
Equity Securities without Readily Determinable Fair Value, Upward Price Adjustment, Cumulative Amount 5,102   $ 779
Equity Securities without Readily Determinable Fair Value, Downward Price Adjustment, Cumulative Amount 15,071   12,528
Other Investment Not Readily Marketable, Fair Value $ 52,227   $ 34,197
v3.24.2
FAIR VALUE MEASUREMENTS - Narrative (Details)
 3 Months Ended 6 Months Ended
Jun. 30, 2024
USD ($)
Jun. 30, 2023
USD ($)
Jun. 30, 2024
USD ($)
Jun. 30, 2023
USD ($)
Dec. 31, 2023
USD ($)
Fair Value, Balance Sheet Grouping, Financial Statement Captions [Line Items]          
Contingent consideration $ 277,921,000   $ 277,921,000   $ 288,657,000
Business Combination, Contingent Consideration, Liability, Current 19,000,000   19,000,000    
Business Combination, Contingent Consideration, Liability, Noncurrent 258,900,000   258,900,000    
Venture capital investment fund          
Fair Value, Balance Sheet Grouping, Financial Statement Captions [Line Items]          
Investment owned, at fair value 6,800,000   6,800,000   $ 5,200,000
Committed capital     18,000,000    
Committed capital callable $ 11,800,000   $ 11,800,000    
Product development and other milestone-based payments | Weighted average | Measurement Input, Probability of Success          
Fair Value, Balance Sheet Grouping, Financial Statement Captions [Line Items]          
Contingent consideration liability, measurement input 0.90   0.90   0.89
Product development and other milestone-based payments | Weighted average | Measurement Input, Present-value Factor          
Fair Value, Balance Sheet Grouping, Financial Statement Captions [Line Items]          
Contingent consideration liability, measurement input 0.061   0.061   0.058
Foreign exchange forward          
Fair Value, Balance Sheet Grouping, Financial Statement Captions [Line Items]          
Derivative, notional amount $ 45,200,000   $ 45,200,000   $ 39,500,000
Derivative, fair value 0   0   0
Gain (Loss) on derivative instruments, net, pretax 0 $ 0 0 $ 0  
Thrive, Ashion and OmicEra | Fair value          
Fair Value, Balance Sheet Grouping, Financial Statement Captions [Line Items]          
Contingent consideration $ 277,900,000   $ 277,900,000   $ 288,700,000
v3.24.2
LONG-TERM DEBT - Narrative (Details) - USD ($)
 1 Months Ended 6 Months Ended
Jan. 31, 2023
Dec. 31, 2021
Nov. 30, 2021
Jun. 30, 2024
Jun. 30, 2023
Jun. 29, 2024
Dec. 31, 2023
Jun. 29, 2022
Long-term debt                
Repayments of Accounts Receivable Securitization       $ 50,000,000 $ 0      
Securitized receivables                
Long-term debt                
Maximum borrowing capacity               $ 150,000,000
Line of credit facility, interest rate at period end           6.89%    
Long-Term Debt, Excluding Current Maturities             $ 50,000,000  
Repayments of Accounts Receivable Securitization       50,000,000        
Securitized receivables | Minimum                
Long-term debt                
Long-Term Debt, Excluding Current Maturities               $ 50,000,000
Revolving loan agreement | Revolving loan agreement | Line of credit                
Long-term debt                
Maximum borrowing capacity     $ 150,000,000          
Minimum market value covenant     150,000,000          
Maximum outstanding cash advances threshold     $ 20,000,000.0          
Variable rate     0.60%          
Remaining borrowing capacity       $ 145,600,000     $ 145,600,000  
City letter of credit | Revolving loan agreement | Line of credit                
Long-term debt                
Proceeds from lines of credit $ 1,500,000 $ 2,900,000            
v3.24.2
CONVERTIBLE NOTES - Schedule of Convertible Notes (Details) - USD ($)
$ in Thousands
Jun. 30, 2024
Dec. 31, 2023
2027 Convertible Notes    
Long-term debt    
Coupon interest rate 0.375% 0.375%
Principal Amount $ 589,380 $ 949,042
Unamortized Debt Discount and Issuance Costs (5,741) (10,499)
Net Carrying Amount 583,639 938,543
2027 Convertible Notes | Significant Other Observable Inputs (Level 2) | Fair value    
Long-term debt    
Amount $ 482,702 $ 887,354
2028 Convertible Notes    
Long-term debt    
Coupon interest rate 0.375% 0.375%
Principal Amount $ 563,822 $ 563,822
Unamortized Debt Discount and Issuance Costs (4,584) (5,429)
Net Carrying Amount 559,238 558,393
2028 Convertible Notes | Significant Other Observable Inputs (Level 2) | Fair value    
Long-term debt    
Amount $ 494,872 $ 549,839
2030 Convertible Notes    
Long-term debt    
Coupon interest rate 1.00% 1.00%
Principal Amount $ 249,172 $ 249,172
Unamortized Debt Discount and Issuance Costs (249) (476)
Net Carrying Amount 248,923 248,696
2030 Convertible Notes | Significant Other Observable Inputs (Level 2) | Fair value    
Long-term debt    
Amount $ 242,943 $ 293,300
Convertible Notes Payable2030    
Long-term debt    
Coupon interest rate 2.00% 2.00%
Principal Amount $ 572,993 $ 572,993
Unamortized Debt Discount and Issuance Costs (3,998) (4,349)
Net Carrying Amount 568,995 568,644
Convertible Notes Payable2030 | Significant Other Observable Inputs (Level 2) | Fair value    
Long-term debt    
Amount $ 513,373 $ 684,475
Convertible Notes Payable2031    
Long-term debt    
Coupon interest rate 1.75%  
Principal Amount $ 620,709  
Unamortized Debt Discount and Issuance Costs (14,633)  
Net Carrying Amount 606,076  
Convertible Notes Payable2031 | Significant Other Observable Inputs (Level 2) | Fair value    
Long-term debt    
Amount $ 510,335  
v3.24.2
CONVERTIBLE NOTES - Narrative (Details)
$ / shares in Units, $ in Thousands, shares in Millions
 1 Months Ended 3 Months Ended 6 Months Ended
Apr. 30, 2024
USD ($)
Mar. 31, 2023
USD ($)
Jun. 30, 2024
USD ($)
$ / shares
Jun. 30, 2023
USD ($)
Jun. 30, 2024
USD ($)
$ / shares
shares
Jun. 30, 2023
USD ($)
Apr. 17, 2024
USD ($)
Dec. 31, 2023
USD ($)
Mar. 06, 2023
USD ($)
Mar. 01, 2023
USD ($)
Long-term debt                    
Principal amount, convertible note         $ 1          
Repurchase price, as percentage of principal amount, if company undergoes change of control         100          
Market price (in dollars per share) | $ / shares     $ 42.25   $ 42.25          
Proceeds from issuance of convertible notes         $ 266,750 $ 137,976        
Gain (Loss) on Extinguishment of Debt $ 10,300 $ 17,700                
Other Investment Not Readily Marketable, Fair Value     $ 52,227 $ 34,197 $ 52,227 $ 34,197        
Significant Unobservable Inputs (Level 3) | Fair value, nonrecurring                    
Long-term debt                    
Other Investment Not Readily Marketable, Fair Value               $ 46,000    
2030 Convertible Notes                    
Long-term debt                    
Gain (Loss) on Extinguishment of Debt   7,400                
2030 Convertible Notes                    
Long-term debt                    
Conversion rate, number of shares to be issued per $1,000 of principal amount (in shares)         13.26          
Conversion price (in dollars per share) | $ / shares     $ 75.43   $ 75.43          
Potential shares issued from convertible instrument (in shares) | shares         3.3          
Effective interest rate (as a percent)     1.18% 1.18% 1.17% 1.18%        
Amount of debt extinguished   65,800                
Interest expense amortization term     6 months 18 days   6 months 18 days          
Convertible Notes Payable2027                    
Long-term debt                    
Conversion rate, number of shares to be issued per $1,000 of principal amount (in shares)         8.96          
Conversion price (in dollars per share) | $ / shares     $ 111.66   $ 111.66          
Potential shares issued from convertible instrument (in shares) | shares         5.0          
Effective interest rate (as a percent)     0.67% 0.67% 0.67% 0.67%        
Amount of debt extinguished   183,700                
Interest expense amortization term     2 years 8 months 15 days   2 years 8 months 15 days          
2027 Convertible Notes                    
Long-term debt                    
Conversion rate, number of shares to be issued per $1,000 of principal amount (in shares)         8.21          
Conversion price (in dollars per share) | $ / shares     $ 121.84   $ 121.84          
Potential shares issued from convertible instrument (in shares) | shares         4.8          
Effective interest rate (as a percent)     0.64% 0.64% 0.63% 0.63%        
Amount of debt extinguished 359,700 201,000                
Interest expense amortization term     3 years 8 months 1 day   3 years 8 months 1 day          
Convertible Notes Payable2030                    
Long-term debt                    
Conversion rate, number of shares to be issued per $1,000 of principal amount (in shares)         12.37          
Conversion price (in dollars per share) | $ / shares     $ 80.83   $ 80.83          
Potential shares issued from convertible instrument (in shares) | shares         7.1          
Effective interest rate (as a percent)     2.12% 2.12% 2.10% 2.10%        
Face amount                   $ 500,000
Proceeds from issuance of convertible notes   138,000                
Proceeds from Debt, Net of Issuance Costs   $ 133,000                
Interest expense amortization term     5 years 8 months 1 day   5 years 8 months 1 day          
Convertible Notes Payable2030 | 2030 Convertible Notes                    
Long-term debt                    
Face amount                 $ 73,000  
Convertible Notes Payable2031                    
Long-term debt                    
Conversion rate, number of shares to be issued per $1,000 of principal amount (in shares)         10.06          
Conversion price (in dollars per share) | $ / shares     $ 99.36   $ 99.36          
Potential shares issued from convertible instrument (in shares) | shares         6.2          
Effective interest rate (as a percent)     2.06% 0.00% 2.06% 0.00%        
Face amount             $ 620,700      
Proceeds from issuance of convertible notes 266,800                  
Proceeds from Debt, Net of Issuance Costs $ 259,800                  
Interest expense amortization term     6 years 9 months 14 days   6 years 9 months 14 days          
v3.24.2
CONVERTIBLE NOTES - Schedule of Transaction Costs (Details)
$ in Thousands
 6 Months Ended
Jun. 30, 2024
USD ($)
Convertible Notes Payable2027  
Long-term debt  
Total transaction costs $ 14,285
Convertible Notes Payable2028  
Long-term debt  
Total transaction costs 24,453
Convertible Notes Payable2030  
Long-term debt  
Total transaction costs 4,938
2030 Convertible Notes  
Long-term debt  
Total transaction costs 17,646
Convertible Notes Payable2031  
Long-term debt  
Total transaction costs $ 6,820
v3.24.2
CONVERTIBLE NOTES - Summary of Interest Expense (Details) - USD ($)
$ in Thousands
 3 Months Ended 6 Months Ended
Jun. 30, 2024
Jun. 30, 2023
Jun. 30, 2024
Jun. 30, 2023
Debt Disclosure [Abstract]        
Debt issuance costs amortization $ 1,316 $ 1,315 $ 2,631 $ 2,692
Debt discount amortization 264 25 289 56
Gain on settlements of convertible notes, net (10,254) 0 (10,254) (10,324)
Coupon interest expense 6,863 4,906 11,770 8,260
Total interest expense (income) on convertible notes $ (1,811) $ 6,246 $ 4,436 $ 684
v3.24.2
CONVERTIBLE NOTES - Schedule of Effective Interest Rates Related to Convertible Debt (Details)
 3 Months Ended 6 Months Ended
Jun. 30, 2024
Jun. 30, 2023
Jun. 30, 2024
Jun. 30, 2023
2030 Convertible Notes        
Schedule of Convertible notes [Line Items]        
Effective interest rate (as a percent) 1.18% 1.18% 1.17% 1.18%
2028 Convertible Notes        
Schedule of Convertible notes [Line Items]        
Effective interest rate (as a percent) 0.67% 0.67% 0.67% 0.67%
2027 Convertible Notes        
Schedule of Convertible notes [Line Items]        
Effective interest rate (as a percent) 0.64% 0.64% 0.63% 0.63%
Convertible Notes Payable2030        
Schedule of Convertible notes [Line Items]        
Effective interest rate (as a percent) 2.12% 2.12% 2.10% 2.10%
Convertible Notes Payable2031        
Schedule of Convertible notes [Line Items]        
Effective interest rate (as a percent) 2.06% 0.00% 2.06% 0.00%
v3.24.2
LICENSE AND COLLABORATION AGREEMENTS - Mayo (Details) - USD ($)
$ in Thousands
 3 Months Ended 6 Months Ended
Jun. 30, 2024
Jun. 30, 2023
Jun. 30, 2024
Jun. 30, 2023
Oct. 31, 2017
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]          
Research and development expense $ 120,884 $ 104,095 $ 231,492 $ 199,514  
Licensing agreements | Mayo          
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]          
Period patent remains in effect     5 years    
Collaborative Arrangements Amount Agreed to Pay upon Achievement of Sale Milestones         $ 3,000
v3.24.2
LICENSE AND COLLABORATION AGREEMENTS - John Hopkins University (Details) - Licensing agreements - USD ($)
$ in Millions
Jun. 30, 2023
Jan. 05, 2021
Resolution Bioscience acquisition    
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]    
Sales-based Milestone Payments   $ 45.0
Sales milestone range one | The Broad Institute, LLC    
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]    
Collaborative arrangement sales milestone amount $ 500.0  
v3.24.2
LICENSE AND COLLABORATION AGREEMENTS - The Broad Institute (Details)
$ in Thousands
Jun. 30, 2023
USD ($)
Product development and other milestone-based payments | The Broad Institute, LLC | Licensing agreements  
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]  
Collaborative Arrangements Development Milestone Amount $ 6,500
v3.24.2
LICENSE AND COLLABORATION AGREEMENTS - Translational Genomics Research Institute (Details) - TARDIS Technology - USD ($)
$ in Thousands
 6 Months Ended
Jun. 30, 2024
May 01, 2024
Jan. 11, 2021
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]      
Sales-based Milestone Payments     $ 45,000
Contract Termination Fee, Unamortized Liability $ 1,800    
Contract Termination, Current Liability 8,700    
Contract Termination, Long Term Liability 8,100    
Contract Termination Fee, Fair-Value   $ 25,800  
Contract Termination Fee, Liability $ 16,800    
Contract termination fee   27,600  
Contract Termination Fee Annual Installments   $ 9,200  
v3.24.2
LICENSE AND COLLABORATION AGREEMENTS - Watchmaker Genomics (Details)
$ in Millions
Jul. 31, 2023
USD ($)
Watchmaker Genomics, Inc | Licensing agreements  
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]  
Collaboration arrangement, milestones to be paid $ 82.0
v3.24.2
STOCKHOLDERS' EQUITY - Schedule of OCI (Details) - USD ($)
$ in Thousands
 6 Months Ended
Jun. 30, 2024
Jun. 30, 2023
AOCI Attributable to Parent, Net of Tax [Roll Forward]    
Beginning balance $ 3,145,305 $ 3,043,162
Other comprehensive income before reclassifications (2,430) 1,660
Amounts reclassified from accumulated other comprehensive income (loss) 59 2,853
Net current period change in accumulated other comprehensive income (loss) (2,371) 4,513
Ending balance 3,192,362 3,056,622
Cumulative Translation Adjustment    
AOCI Attributable to Parent, Net of Tax [Roll Forward]    
Beginning balance 1,374 53
Other comprehensive income before reclassifications (1,446) 609
Amounts reclassified from accumulated other comprehensive income (loss) 0 0
Net current period change in accumulated other comprehensive income (loss) (1,446) 609
Ending balance (72) 662
Unrealized Gain (Loss) on Marketable Securities    
AOCI Attributable to Parent, Net of Tax [Roll Forward]    
Beginning balance 54 (5,289)
Other comprehensive income before reclassifications (984) 1,051
Amounts reclassified from accumulated other comprehensive income (loss) 59 2,853
Net current period change in accumulated other comprehensive income (loss) (925) 3,904
Ending balance (871) (1,385)
AOCI    
AOCI Attributable to Parent, Net of Tax [Roll Forward]    
Beginning balance 1,428 (5,236)
Ending balance $ (943) $ (723)
v3.24.2
STOCKHOLDERS' EQUITY - Schedule of Amounts Reclassified from AOCI (Details) - Reclassification out of accumulated other comprehensive income - USD ($)
$ in Thousands
 6 Months Ended
Jun. 30, 2024
Jun. 30, 2023
Changes in Accumulated Other Comprehensive Income (Loss)    
Total reclassifications $ 59 $ 2,853
Unrealized Gain (Loss) on Marketable Securities    
Changes in Accumulated Other Comprehensive Income (Loss)    
Investment income, net $ 59 $ 2,853
v3.24.2
STOCK-BASED COMPENSATION - Narrative (Details) - USD ($)
$ in Thousands
 3 Months Ended 6 Months Ended
Jun. 30, 2024
Mar. 31, 2024
Jun. 30, 2023
Mar. 31, 2023
Jun. 30, 2024
Jun. 30, 2023
Stock-based compensation            
Stock-based compensation expense $ 56,555 $ 60,370 $ 61,725 $ 49,139 $ 116,900 $ 110,900
Stock plans            
Stock-based compensation            
Unrecognized compensation cost $ 450,000       $ 450,000  
Weighted average period for recognition of cost         2 years 8 months 12 days  
v3.24.2
STOCK-BASED COMPENSATION - Fair Value and Activity (Details) - Stock plans - USD ($)
$ / shares in Units, $ in Thousands
 6 Months Ended
Dec. 31, 2023
Jun. 30, 2024
Jun. 30, 2023
Shares      
Outstanding at the beginning of the period (in shares)   1,286,173  
Exercised (in shares)   (141,503)  
Forfeited (in shares)   (17,164)  
Outstanding at the end of the period (in shares) 1,286,173 1,127,506  
Vested and expected to vest at end of period (in shares)   1,127,506  
Exercisable at the end of the period (in shares)   1,127,506  
Weighted Average Exercise Price      
Outstanding at the beginning of the period (in dollars per share)   $ 47.67  
Exercised (in dollars per share)   15.44  
Forfeited (in dollars per share)   94.85  
Outstanding at the end of the period (in dollars per share) $ 47.67 51.00  
Vested and expected to vest at end of period (in dollars per share)   51.00  
Exercisable at the end of the period (in dollars per share)   $ 51.00  
Weighted Average Remaining Contractual Term      
Outstanding 3 years 9 months 18 days 3 years 7 months 6 days  
Vested and expected to vest at end of period   3 years 7 months 6 days  
Exercisable at the end of the period   3 years 7 months 6 days  
Aggregate Intrinsic Value      
Outstanding at the end of the period   $ 11,834  
Vested and expected to vest at end of period   11,834  
Exercisable at the end of the period   11,834  
Total intrinsic value of options exercised   $ 3,300 $ 7,000
v3.24.2
STOCK-BASED COMPENSATION - Share-based Payment Arrangement, Restricted Stock and Restricted Stock Unit, Activity (Details) - USD ($)
$ / shares in Units, $ in Millions
 6 Months Ended
Jun. 30, 2024
Jun. 30, 2023
Restricted Shares and RSUs    
Restricted Shares    
Outstanding at the beginning of the period (in shares) 6,272,763  
Granted (in shares) 3,937,097  
Released (in shares) (1,924,514)  
Forfeited (in shares) (504,123)  
Outstanding at the end of the period (in shares) 7,781,223  
Weighted Average Exercise Price    
Outstanding at the beginning of the period (in dollars per share) $ 73.39  
Granted (in dollars per share) 57.38  
Released (in dollars per share) 79.93  
Forfeited (in dollars per share) 64.23  
Outstanding at the end of the period (in dollars per share) $ 63.97  
Fair value of equity instruments other than options vested in period $ 153.4 $ 130.5
Restricted stock units    
Weighted Average Exercise Price    
Granted (in dollars per share)   $ 60.94
v3.24.2
STOCK-BASED COMPENSATION - Share-based Payment Arrangement, Performance Shares, Activity (Details) - Shares issuable upon the release of performance share units - USD ($)
$ / shares in Units, $ in Millions
 6 Months Ended
Jun. 30, 2024
Jun. 30, 2023
Dec. 31, 2023
Stock-based compensation      
Outstanding (in shares) 2,103,820   1,597,801
Outstanding (in dollars per share) $ 74.25   $ 92.73
Granted (in shares) 913,533    
Granted (in dollars per share) $ 63.68 $ 79.17  
Released (in shares) (70,662)    
Released (in dollars per share) $ 140.20    
Forfeited (in shares) (336,852)    
Forfeited (in dollars per share) $ 106.06    
Number of outstanding performance share units (in shares) 1,037,206    
Fair value of equity instruments other than options vested in period $ 9.9 $ 1.0  
v3.24.2
STOCK-BASED COMPENSATION - Schedule of Share-based Payment Award, Employee Stock Purchase Plan, Valuation Assumptions (Details)
 3 Months Ended 6 Months Ended
Jun. 30, 2024
Jun. 30, 2023
Jun. 30, 2024
Jun. 30, 2023
Stock-based compensation        
Risk-free interest rates, maximum (as a percent) 5.30%   5.30%  
Expected volatility, maximum (as a percent) 63.13%   63.13%  
Employee stock        
Stock-based compensation        
Risk-free interest rates, minimum (as a percent) 4.71% 4.68% 4.71% 4.68%
Expected Volatility Rate, Minimum (as a percent) 55.67% 67.30% 55.67% 67.30%
Dividend yield (as a percent) 0.00% 0.00% 0.00%  
Employee stock | Minimum        
Stock-based compensation        
Expected term (in years) 1 year 2 months 1 day 1 year 3 months 1 year 2 months 1 day 1 year 3 months
v3.24.2
COMMITMENTS AND CONTINGENCIES - Supplemental Disclosure of Cash Flow Information (Details) - USD ($)
$ in Thousands
 6 Months Ended
Jun. 30, 2024
Jun. 30, 2023
Cash paid for amounts included in the measurement of lease liabilities:    
Operating cash flows from operating leases $ 19,188 $ 19,093
Operating cash flows from finance leases 612 342
Finance cash flows from finance leases 3,025 1,561
Non-cash investing and financing activities:    
Right-of-use assets obtained in exchange for new operating lease liabilities (18,925) (5,375)
Right-of-use assets obtained in exchange for new finance lease liabilities $ 13,717 $ 2,670
Weighted-average remaining lease term - operating leases (in years) 7 years 8 months 23 days 7 years 2 months 12 days
Weighted-average remaining lease term - finance leases (in years) 3 years 2 months 15 days 3 years 14 days
Weighted-average discount rate - operating leases 6.55% 6.41%
Weighted-average discount rate - finance leases 6.78% 7.03%
Operating Lease, Right-of-Use Asset Modification   $ 8,600
v3.24.2
COMMITMENTS AND CONTINGENCIES - Additional Information (Details) - USD ($)
$ in Thousands
Jun. 30, 2024
Dec. 31, 2023
Lessee, Lease, Description [Line Items]    
Operating lease right-of-use assets $ 139,807 $ 143,708
Additional amount to be recognized at lease commencement for the lease liability 194,800 190,400
Operating lease liability, current 27,096 29,379
Operating lease liability, noncurrent 167,665 161,070
Finance lease, right-of-use asset $ 21,400 11,300
Finance lease, right-of-use asset, statement of financial position, extensible list Other long-term assets, net  
Finance lease liability $ 22,300 11,900
Finance lease liability, current $ 7,300 $ 4,400
Finance lease, liability, current, statement of financial position, extensible list Other current liabilities Other current liabilities
Finance lease liability, noncurrent $ 15,000 $ 7,500
Finance lease, liability, noncurrent, statement of financial position, extensible list Other long-term liabilities Other long-term liabilities
v3.24.2
WISCONSIN ECONOMIC DEVELOPMENT TAX CREDITS (Details) - Amended wisconsin economic development tax credit agreement
$ in Millions
 1 Months Ended
Dec. 31, 2021
USD ($)
position
Jun. 30, 2024
USD ($)
Agreements    
Capital investment expenditures over specified period, requirement to earn the refundable tax credits $ 350.0  
Full-time positions that must be created over a specified time period to earn the refundable tax credits | position 1,300  
Period over which the capital investment expenditures must be incurred and the creation of full-time positions must be completed 5 years  
Refundable tax credits earned $ 18.5 $ 14.3
Credit earning rate 10.00%  
Maximum credits available to earn $ 7.0  
Refundable tax credit receivable   8.8
Prepaid expenses and other current assets    
Agreements    
Refundable tax credit receivable   4.2
Other long-term assets    
Agreements    
Refundable tax credit receivable   $ 4.6
v3.24.2
ACQUISITIONS AND DIVESTITURES - Narrative (Details) - USD ($)
$ in Millions
Jun. 30, 2024
Dec. 31, 2023
Business Acquisition [Line Items]    
Contract asset $ 45.2 $ 41.7
Contract with Customer, Receivable, after Allowance for Credit Loss 31.6 $ 31.6
Contract with Customer, Asset, after Allowance for Credit Loss, Current 24.1  
Contract with Customer, Asset, after Allowance for Credit Loss, Noncurrent $ 21.1  
Developed Technology Rights    
Business Acquisition [Line Items]    
Weighted-average remaining useful life of finite-lived intangible asset (in years) 6 years 9 months 18 days 7 years 3 months 18 days
v3.24.2
ACQUISITIONS AND DIVESTITURES - Schedule of Recognized Identified Assets Acquired and Liabilities Assumed (Details) - USD ($)
$ in Thousands
Jun. 30, 2024
Dec. 31, 2023
Dec. 31, 2022
Business Acquisition [Line Items]      
Goodwill $ 2,366,972 $ 2,367,120 $ 2,346,040
v3.24.2
SEGMENT INFORMATION (Details)
$ in Thousands
 3 Months Ended 6 Months Ended
Jun. 30, 2024
USD ($)
Jun. 30, 2023
USD ($)
Jun. 30, 2024
USD ($)
segment
Jun. 30, 2023
USD ($)
Segment Reporting, Revenue Reconciling Item [Line Items]        
Revenue $ 699,264 $ 622,093 $ 1,336,788 $ 1,224,543
Number of operating segments | segment     1  
United States        
Segment Reporting, Revenue Reconciling Item [Line Items]        
Revenue 652,542 586,507 $ 1,245,533 1,151,689
Outside of United States        
Segment Reporting, Revenue Reconciling Item [Line Items]        
Revenue $ 46,722 $ 35,586 $ 91,255 $ 72,854
v3.24.2
INCOME TAXES (Details) - USD ($)
$ in Thousands
 3 Months Ended 6 Months Ended
Jun. 30, 2024
Jun. 30, 2023
Jun. 30, 2024
Jun. 30, 2023
Dec. 31, 2023
Income Tax Disclosure [Abstract]          
Tax expense (benefit) $ 1,463 $ 1,107 $ 3,269 $ 2,764  
Deferred tax liabilities, net 19,100   19,100   $ 17,300
Unrecognized tax benefits $ 40,100   $ 40,100   $ 36,400
v3.24.2
SUBSEQUENT EVENTS (Details) - USD ($)
$ in Thousands
 1 Months Ended 6 Months Ended
Jul. 01, 2024
Apr. 30, 2024
Mar. 31, 2023
Jun. 30, 2024
Jun. 30, 2023
Apr. 17, 2024
Dec. 31, 2023
Subsequent Event [Line Items]              
Proceeds from issuance of convertible notes       $ 266,750 $ 137,976    
Convertible Notes Payable2031              
Subsequent Event [Line Items]              
Face amount           $ 620,700  
Proceeds from issuance of convertible notes   $ 266,800          
Proceeds from Debt, Net of Issuance Costs   259,800          
Interest rate (as a percent)       1.75%      
Convertible Notes Payable2028              
Subsequent Event [Line Items]              
Amount of debt extinguished   $ 359,700 $ 201,000        
Interest rate (as a percent)       0.375%     0.375%
Subsequent event              
Subsequent Event [Line Items]              
Payments to acquire productive assets $ 45,000            
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