New Evidence on Infection as Chronic Disease Trigger Published, Debated by World-Class Scientists
2007年2月1日 - 1:56AM
ビジネスワイヤ(英語)
Nanobac Pharmaceuticals Inc. (OTCBB:NNBP) ("Nanobac" or "the
Company") announces new evidence that may help solve one of the
great puzzles of 21st century medicine was published today in a
special section of the Journal of Investigative Medicine. It
features leading scientists in the field brought together by The
American Federation for Medical Research and the American
Physiological Society. Is chronic disease triggered by an
infection? New evidence comes from scientists at NASA, Mayo Clinic,
and Nanobac Pharmaceuticals who pioneered investigations into
infectious calcifying particles. A condition known as calcification
occurs in most diseases on the leading cause of death list and in
illnesses such as kidney, gallbladder and prostate stones.
Calcification is also linked to chronic inflammation in
atherosclerosis and end-stage renal disease, but it is unclear how
this occurs. Half-a-dozen papers in the Journal resulted from a
symposium that assembled, for the first time in medical history,
experts from biology, medicine and geology to debate these possible
causes of calcification: chemical crystallization; cell-mediated
crystallization; and potentially infectious calcifying
nanoparticles (CNPs) that generate calcification. One conclusion by
symposium organizers: Although infection is just one of three
potential causes of calcification, it deserves focus as a chronic
disease trigger, based on new evidence presented. "Increasingly,
micro-organisms are being identified as an unexpected cause of
disease..." writes symposium co-organizer and Mayo Clinic scientist
Dr. Virginia Miller. The symposium considered works by Dr. Neva
Ciftcioglu and Dr. Olavi Kajander, lead scientists with Nanobac
Pharmaceuticals, as well as two other works by Mayo researchers,
which provide evidence that calcifying nanoparticles might be
infectious and spark calcification in disease. Although Dr. Miller
says the idea of infectious nanoparticles is still controversial,
she concludes that, "Nanoparticles might serve as an inflammatory
stimulus that initiates cell transdifferentiation, stimulate the
formation of matrix vesicles, or simply form a nidus for subsequent
inorganic calcium accumulation." Participants in the symposium
included scientists from such world-class institutions as UCLA and
various institutes in Europe. Scientists from Nanobac
Pharmaceuticals are the leading investigators on the issue of
infection as a possible cause of calcification, and have published
the most papers on this topic. Nanobac Pharmaceuticals Inc. is
headquartered in Tampa, Florida. For more information, visit our
website at: http://www.nanobac.com. Investors are cautioned that
certain statements in this document, some statements in periodic
press releases and some oral statements of Nanobac Pharmaceuticals,
Inc. officials are "Forward-Looking Statements" within the meaning
of the Private Securities Litigation Reform Act of 1995 (the
"Act"). Forward-Looking statements include statements which are
predictive in nature, which depend upon or refer to future events
or conditions, which include words such as "believes,"
"anticipates," "intends," "plans," "expects," and similar
expressions. In addition, any statements concerning future
financial performance (including future revenues, earnings or
growth rates), ongoing business strategies or prospects, and
possible future Nanobac Pharmaceuticals, Inc. actions, which may be
provided by management, are also forward-looking statements as
defined by the Act. Forward-Looking statements involve known and
unknown risks, uncertainties, and other factors which may cause the
actual results, performance or achievements of the Company to
materially differ from any future results, performance or
achievements expressed or implied by such forward-looking
statements and to vary significantly from reporting period to
reporting period. Although management believes that the assumptions
will, in fact, prove to be correct or that actual future results
will not be different from the expectations expressed in this
report. These statements are not guarantees of future performance
and Nanobac Pharmaceuticals, Inc. has no specific intention to
update these statements.
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