AACR Data Highlights InNexus Preclinical Antibody Candidate
2009年4月9日 - 10:00PM
PRニュース・ワイアー (英語)
- Additional Presentations Underscore Potency, Binding Capabilities
for Antibody Pipeline And Novel Technologies - SCOTTSDALE, Ariz.,
April 9 /PRNewswire-FirstCall/ -- InNexus Biotechnology Inc.
(Toronto Stock Exchange: IXS.V, http://www.ixsbio.com/), a drug
development company commercializing the next generation of
monoclonal antibodies based on its technology, Dynamic Cross
Linking (DXL(TM)), announced today that the company will be
presenting new data on its lead preclinical candidate DXL625 (CD20)
for the prospective treatment of Non Hodgkin's Lymphoma (NHL) at
the annual meeting of the American Association for Cancer Research
(AACR), April 18-22, in Denver. "Preclinical data on DXL625
indicates the strong promise of this candidate as a prospective
treatment for NHL and Chronic Lymphatic Leukemia (CLL), and we
anticipate starting clinical trials in the near term," said Dr.
Thomas Kindt, Chief Scientific Officer of InNexus. "The AACR will
also feature a scientific presentation on our novel, proprietary
approach for creating 'programmed' self-binding properties into
antibodies. The increased potency of the antibody resulting from
this technique suggests a new way to enhance antibody performance."
Jeff Morhet, Chairman and Chief Executive Officer of InNexus, said,
"InNexus has executed a focused and accelerated development plan
for DXL625, while efficiently discovering promising new therapeutic
candidates and supportive technologies. InNexus remains a novel,
and independent, 'pure-play' antibody development company--an
unusual investment and commercial opportunity." InNexus' AACR
presentations are titled, "A Novel High Avidity Anti-CD20 With
Markedly Increased Cytotoxicity Shows No Systemic Toxicity In The
Cynomolgus Monkey At A Dose 100-Fold Above The Anticipated
Therapeutic Dose", (AACR# 1231) and "Oxidative Modification Of An
Anti-CD20 Antibody Imparts Autophilic Binding Kinetics", (AACR#
1230). Posters and company representatives will also be available
within the AACR Antibody and Antibody Targets Session from
1:00-5:00 PM on April 19th in Hall B-F, Poster Section 12. The
posters will also be available via the InNexus website beginning
April 19th. About InNexus InNexus is a drug development company
commercializing the next generation of monoclonal antibodies based
on its DXL technology, which improves the potency of existing
antibody products while opening new markets and disease
applications. DXL antibodies utilize unique, novel and patented
methods and technologies of InNexus. InNexus is headquartered in
British Columbia with principal management based in Scottsdale,
Arizona on the campus of Mayo Clinic and has its own in-house
developmental facilities. These development resources provide
validation of protein and peptide discoveries, enabling InNexus
(and its strategic partners) to advance novel drug therapeutics and
diagnostics. To learn more about InNexus, please visit
http://www.ixsbio.com/. The TSX Venture Exchange has not reviewed
and does not accept responsibility for the adequacy or accuracy of
this news release. This news release may contain assumptions,
estimates, and other forward-looking statements that involve
inherent risks and uncertainties and are subject to factors, many
of which are beyond the Company's control, which may cause actual
results or performance to differ materially from those currently
anticipated in such statements. DATASOURCE: InNexus Biotechnology
Inc. CONTACT: Jeff Morhet, Chairman & Chief Executive Officer,
or Dr. Thomas Kindt, Chief Scientific Officer, both of InNexus
Biotechnology Inc., +1-480-862-7500 Web Site:
http://www.ixsbio.com/
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