Check the appropriate box to designate the
rule pursuant to which this Schedule is filed:
*The remainder of this cover page shall be
filled out for a reporting person’s initial filing on this form with respect to the subject class of securities, and for any subsequent
amendment containing information which would alter the disclosures provided in a prior cover page.
The information required in the remainder
of this cover page shall not be deemed to be “filed” for the purpose of Section 18 of the Securities Exchange Act of
1934 (“Act”) or otherwise subject to the liabilities of that section of the Act but shall be subject to all other provisions
of the Act (however, see the Notes).
CUSIP No. 206022105
1 |
NAMES OF REPORTING PERSONS
I.R.S. IDENTIFICATION NOS. OF ABOVE PERSONS (ENTITIES ONLY)
RA Capital Management, L.P. |
2 |
CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (SEE INSTRUCTIONS)
(a) ¨
(b) ¨ |
3 |
SEC USE ONLY
|
4 |
CITIZENSHIP OR PLACE OF ORGANIZATION
Delaware |
NUMBER OF
SHARES
BENEFICIALLY
OWNED BY
EACH
REPORTING
PERSON
WITH: |
5 |
SOLE VOTING POWER
0 |
6 |
SHARED VOTING POWER
5,199,746 |
7 |
SOLE DISPOSITIVE POWER
0 |
8 |
SHARED DISPOSITIVE POWER
5,199,746 |
9 |
AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
5,199,746 |
10 |
CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES (SEE INSTRUCTIONS) ¨
|
11 |
PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW 9
9.99% |
12 |
TYPE OF REPORTING PERSON (SEE INSTRUCTIONS)
IA, PN |
|
|
|
|
CUSIP No. 206022105
1 |
NAMES OF REPORTING PERSONS
I.R.S. IDENTIFICATION NOS. OF ABOVE PERSONS (ENTITIES ONLY)
Peter Kolchinsky |
2 |
CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (SEE INSTRUCTIONS)
(a) ¨
(b) ¨ |
3 |
SEC USE ONLY
|
4 |
CITIZENSHIP OR PLACE OF ORGANIZATION
United States of America |
NUMBER OF
SHARES
BENEFICIALLY
OWNED BY
EACH
REPORTING
PERSON
WITH: |
5 |
SOLE VOTING POWER
0 |
6 |
SHARED VOTING POWER
5,199,746 |
7 |
SOLE DISPOSITIVE POWER
0 |
8 |
SHARED DISPOSITIVE POWER
5,199,746 |
9 |
AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
5,199,746 |
10 |
CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES (SEE INSTRUCTIONS) ¨
|
11 |
PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW 9
9.99% |
12 |
TYPE OF REPORTING PERSON (SEE INSTRUCTIONS)
HC, IN |
|
|
|
|
CUSIP No. 206022105
1 |
NAMES OF REPORTING PERSONS
I.R.S. IDENTIFICATION NOS. OF ABOVE PERSONS (ENTITIES ONLY)
Rajeev Shah |
2 |
CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (SEE INSTRUCTIONS)
(a) ¨
(b) ¨ |
3 |
SEC USE ONLY
|
4 |
CITIZENSHIP OR PLACE OF ORGANIZATION
United States of America |
NUMBER OF
SHARES
BENEFICIALLY
OWNED BY
EACH
REPORTING
PERSON
WITH: |
5 |
SOLE VOTING POWER
0 |
6 |
SHARED VOTING POWER
5,199,746 |
7 |
SOLE DISPOSITIVE POWER
0 |
8 |
SHARED DISPOSITIVE POWER
5,199,746 |
9 |
AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
5,199,746 |
10 |
CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES (SEE INSTRUCTIONS) ¨
|
11 |
PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW 9
9.99% |
12 |
TYPE OF REPORTING PERSON (SEE INSTRUCTIONS)
HC, IN |
|
|
|
|
CUSIP No. 206022105
1 |
NAMES OF REPORTING PERSONS
I.R.S. IDENTIFICATION NOS. OF ABOVE PERSONS (ENTITIES ONLY)
RA Capital Healthcare Fund, L.P. |
2 |
CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (SEE INSTRUCTIONS)
(a) ¨
(b) ¨ |
3 |
SEC USE ONLY
|
4 |
CITIZENSHIP OR PLACE OF ORGANIZATION
Delaware |
NUMBER OF
SHARES
BENEFICIALLY
OWNED BY
EACH
REPORTING
PERSON
WITH: |
5 |
SOLE VOTING POWER
0 |
6 |
SHARED VOTING POWER
5,199,746 |
7 |
SOLE DISPOSITIVE POWER
0 |
8 |
SHARED DISPOSITIVE POWER
5,199,746 |
9 |
AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
5,199,746 |
10 |
CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES (SEE INSTRUCTIONS) ¨
|
11 |
PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW 9
9.99% |
12 |
TYPE OF REPORTING PERSON (SEE INSTRUCTIONS)
PN |
|
|
|
|
| Item 1(a). | Name of Issuer: |
Concert Pharmaceuticals, Inc. (the “Issuer”)
| Item 1(b). | Address
of Issuer’s Principal Executive Offices: |
65 Hayden Avenue, Suite 3000N, Lexington, MA 02421
| Item 2(a). | Names
of Persons Filing: |
The names of the persons filing this report (collectively,
the “Reporting Persons”) are:
RA Capital Management, L.P. (“RA Capital”)
Peter Kolchinsky
Rajeev Shah
RA Capital Healthcare Fund, L.P. (the “Fund”)
| Item 2(b). | Address
of Principal Business Office or, if None, Residence: |
The address of the principal business office of each of
the Reporting Persons is:
c/o RA Capital Management, L.P., 200 Berkeley Street, 18th
Floor, Boston MA 02116
RA Capital and the Fund are Delaware limited partnerships.
Dr. Kolchinsky and Mr. Shah are United States citizens.
| Item 2(d). | Title
of Class of Securities: |
Common stock, $0.001 par value per
share (“Common Stock”)
206022105
| Item 3. | If
this statement is filed pursuant to §§ 240.13d-1(b) or 240.13d-2(b) or
(c), check whether the person filing is
a: |
(e) RA Capital Management, L.P. is a registered investment
adviser and is filing this statement in accordance with §240.13d-1(b)(1)(ii)(E);
(g) Peter Kolchinsky and Rajeev Shah are control persons
and are filing this statement in accordance with §240.13d-1(b)(1)(ii)(G).
The Fund directly holds (i) 1,088,296 shares of Common
Stock and (ii) 11,250 shares of the Issuer’s Series X1 Preferred Stock, which are convertible into an aggregate of 11,250,000
shares of Common Stock, subject to a Series X1 Conversion Limitation (as defined below).
The shares reported herein for the Reporting Persons represent
(i) 1,088,296 shares of Common Stock directly held, and (ii) 4,111,450 shares of Common Stock that the Reporting Persons beneficially
own based on the right to acquire, upon the conversion of Series X1 Preferred Stock. The Series X1 Preferred Stock may not
be converted if, after such conversion, the Reporting Persons would beneficially own, as determined in accordance with Section 13(d) of
the Securities Exchange Act of 1934, as amended (the “Exchange Act”), more than 9.99% of the number of shares of Common Stock
then issued and outstanding (the “Series X1 Conversion Limitation”). The Reporting Persons are currently prohibited
from converting the Series X1 Preferred Stock to the extent that exercise would result in ownership of more than 5,199,746 shares
of Common Stock.
The information required by this item with respect to each
Reporting Person is set forth in Rows 5 through 9 and 11 of the cover page to this Schedule 13G/A. The ownership percentages reported
are based on 47,938,188 outstanding shares of Common Stock, as reported in the Issuer’s Form 10-Q filed on November 7,
2022, plus (ii) 4,111,450 shares of Common Stock of which the Reporting Person may acquire beneficial ownership upon the conversion
of Series X1 Preferred Stock, as limited by the Series X1 Conversion Limitation.
RA Capital Healthcare Fund GP, LLC is the general partner
of the Fund. The general partner of RA Capital is RA Capital Management GP, LLC, of which Dr. Kolchinsky and Mr. Shah are the
controlling persons. RA Capital serves as investment adviser for the Fund and may be deemed a beneficial owner, for purposes of Section 13(d) of
the Act, of any securities of the Issuer held by the Fund. The Fund has delegated to RA Capital the sole power to vote and the sole power
to dispose of all securities held in the Fund’s portfolio, including the shares of the Issuer’s Common Stock reported herein.
Because the Fund has divested voting and investment power over the reported securities it holds and may not revoke that delegation on
less than 61 days’ notice, the Fund disclaims beneficial ownership of the securities it holds for purposes of Section 13(d) of
the Act. As managers of RA Capital, Dr. Kolchinsky and Mr. Shah may be deemed beneficial owners, for purposes of Section 13(d) of
the Act, of any securities of the Issuer beneficially owned by RA Capital. RA Capital, Dr. Kolchinsky, and Mr. Shah disclaim
beneficial ownership of the securities reported in this Schedule 13G/A other than for the purpose of determining their obligations under
Section 13(d) of the Act, and the filing of this Schedule 13G/A shall not be deemed an admission that either RA Capital, Dr. Kolchinsky,
or Mr. Shah is the beneficial owner of such securities for any other purpose.
| Item 5. | Ownership
of Five Percent or Less of a Class. |
If
this statement is being filed to report the fact that as of the date hereof the Reporting Persons have ceased to be the beneficial owner
of more than five percent of the class of securities, check the following ¨.
| Item 6. | Ownership
of More than Five Percent on Behalf of Another Person. |
Not applicable.
| Item 7. | Identification
and Classification of the Subsidiary Which Acquired the Security Being Reported on by the
Parent Holding Company or Control Person. |
Not applicable.
| Item 8. | Identification
and Classification of Members of the Group. |
Not applicable.
| Item 9. | Notice
of Dissolution of Group. |
Not applicable.
By signing below I certify that, to the best of my knowledge
and belief, the securities referred to above were acquired and are held in the ordinary course of business and were not acquired and
are not held for the purpose of or with the effect of changing or influencing the control of the issuer of the securities and were not
acquired and are not held in connection with or as a participant in any transaction having that purpose or effect, other than activities
solely in connection with a nomination under § 240.14a-11.
Exhibit List
Exhibit 1: Joint Filing Agreement
SIGNATURE
After reasonable inquiry and to the best of its
knowledge and belief, each of the undersigned certifies that the information set forth in this statement is true, complete and correct.
Date: |
February 14, 2023 |
|
|
|
RA CAPITAL MANAGEMENT, L.P. |
|
|
|
By: |
/s/ Peter Kolchinsky |
|
|
Name: |
Peter Kolchinsky |
|
|
Title: |
Authorized Signatory |
|
|
|
PETER KOLCHINSKY |
|
|
|
/s/ Peter Kolchinsky |
|
|
|
RAJEEV SHAH |
|
|
|
/s/ Rajeev Shah |
|
|
|
RA CAPITAL HEALTHCARE FUND, L.P. |
|
|
|
By: |
RA Capital Healthcare Fund GP, LLC |
|
Its: |
General Partner |
|
|
|
By: |
/s/ Peter Kolchinsky |
|
|
Name: |
Peter Kolchinsky |
|
|
Title: |
Manager |
|
EXHIBIT 1
AGREEMENT
This Joint Filing Agreement, dated as of February 14, 2023, is by and
among RA Capital Management, L.P., Peter Kolchinsky, Rajeev Shah, and RA Capital Healthcare Fund, L.P. (the foregoing are collectively
referred to herein as the “Filers”).
Each of the Filers may be required to file with the United States
Securities and Exchange Commission a statement on Schedule 13G and/or 13D with respect to Common Stock, $0.001 par value per share of
Concert Pharmaceuticals, Inc. beneficially owned by them from time to time.
Pursuant to and in accordance with Rule 13(d)(1)(k) promulgated under
the Securities Exchange Act of 1934, as amended, the Filers hereby agree to file a single statement on Schedule 13G and/or 13D (and any
amendments thereto) on behalf of each of such parties, and hereby further agree to file this Joint Filing Agreement as an exhibit to such
statement, as required by such rule.
This Joint Filing Agreement may be terminated by any of the Filers
upon one week’s prior written notice or such lesser period of notice as the Filers may mutually agree.
Executed and delivered as of the date first above written.
RA CAPITAL MANAGEMENT, L.P. |
|
|
|
By: |
/s/ Peter Kolchinsky |
|
|
Name: |
Peter Kolchinsky |
|
|
Title: |
Authorized Signatory |
|
|
|
PETER KOLCHINSKY |
|
|
|
/s/ Peter Kolchinsky |
|
|
|
RAJEEV SHAH |
|
|
|
/s/ Rajeev Shah |
|
|
|
RA CAPITAL HEALTHCARE FUND, L.P. |
|
|
|
By: |
RA Capital Healthcare Fund GP, LLC |
|
Its: |
General Partner |
|
|
|
By: |
/s/ Peter Kolchinsky |
|
|
Name: |
Peter Kolchinsky |
|
|
Title: |
Manager |
|