TIDMTTM TIDMPLE 
 
Form 8.3 - Plethora - Position Dealing Disclosure 
                                                                                          FORM 8.3 
 
                     PUBLIC OPENING POSITION DISCLOSURE/DEALING DISCLOSURE BY 
              A PERSON WITH INTERESTS IN RELEVANT SECURITIES REPRESENTING 1% OR MORE 
                            Rule 8.3 of the Takeover Code (the "Code") 
 
1.      KEY INFORMATION 
 
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(a)Full name of discloser:                                      Baker Bros. Advisors LP 
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(b)Owner or controller of interests and short positions 
   disclosed, if different from 1(a): 
   The naming of nominee or vehicle companies is 
   insufficient.  For a trust, the trustee(s), settlor and 
   beneficiaries must be named. 
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(c)Name of offeror/offeree in relation to whose relevant        PLETHORA SOLUTIONS HOLDINGS PLC 
   securities this form relates: 
   Use a separate form for each offeror/offeree 
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(d)If an exempt fund manager connected with an 
   offeror/offeree, state this and specify identity of 
   offeror/offeree: 
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(e)Date position held/dealing undertaken:                       March 3, 2016 
   For an opening position disclosure, state the latest 
   practicable date prior to the disclosure 
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(f)In addition to the company in 1(c) above, is the discloser   NO 
   making disclosures in respect of any other party to the 
   offer? 
   If it is a cash offer or possible cash offer, state 
   "N/A" 
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2.POSITIONS OF THE PERSON MAKING THE DISCLOSURE 
 
If there are positions or rights to subscribe to disclose in more than one class of relevant securities of the offeror 
or offeree named in 1(c), copy table 2(a) or (b) (as appropriate) for each additional class of relevant security. 
 
(a)    Interests and short positions in the relevant securities of the offeror or offeree to which the disclosure 
       relates following the dealing (if any) 
 
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Class of relevant security:                                    1p Ordinary 
 
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                                                    Interests                   Short positions 
                                               ------------------------------------------------------- 
                                               Number            %           Number            % 
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(1)Relevant securities owned and/or             41,181,385        5.00 
   controlled: 
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(2)Cash-settled derivatives: 
 
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(3)Stock-settled derivatives (including 
   options) and agreements to 
   purchase/DEALING: 
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                                                41,181,385        5.00 
   TOTAL: 
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Class of relevant security:                               Fund raising warrants 
 
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                                                 Interests                   Short positions 
                                              -------------------------------------------------------- 
                                               Number            %            Number           % 
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(1)Relevant securities owned and/or             28,619,528        28.29 
   controlled: 
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(2)Cash-settled derivatives: 
 
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(3)Stock-settled derivatives (including 
   options) and agreements to 
   purchase/DEALING: 
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                                                28,619,528        28.29 
   TOTAL: 
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All interests and all short positions should be disclosed. 
 
Details  of  any open stock-settled derivative positions (including traded options), or agreements 
to  purchase  or  sell  relevant  securities, should be given  on  a  Supplemental  Form  8  (Open 
Positions). 
 
(b)     Rights to subscribe for new securities (including directors' and other employee options) 
 
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Class of relevant security in relation to 
which subscription right exists: 
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Details, including nature of the rights 
concerned and relevant percentages: 
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3.      DEALINGS (IF ANY) BY THE PERSON MAKING THE DISCLOSURE 
 
Where  there  have been dealings in more than one class of relevant securities of the  offeror  or 
offeree named in 1(c), copy table 3(a), (b), (c) or (d) (as appropriate) for each additional class 
of relevant security dealt in. 
 
The currency of all prices and other monetary amounts should be stated. 
 
(a)     Purchases and sales 
 
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  Class of relevant           Purchase/DEALING        Number of securities        Price per unit 
       security 
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Ordinary 1p                 Sale                             5,000,000         3.00p 
 
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(b)     Cash-settled derivative transactions 
 
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Class of relevant      Product            Nature of dealing          Number of      Price per unit 
    security         description       e.g. opening/closing a        reference 
                      e.g. CFD          long/short position,         securities 
                                        increasing/reducing a 
                                         long/short position 
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(c)     Stock-settled derivative transactions (including options) 
 
(i)     Writing, selling, purchasing or varying 
 
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Class of      Product        Writing,       Number of    Exercise       Type      Expiry      Option 
relevant    description     purchasing,    securities   price per       e.g.       date       money 
security     e.g. call       selling,       to which       unit      American,                paid/ 
              option       varying etc.      option                   European               received 
                                             relates                    etc.                 per unit 
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(ii)    Exercise 
 
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Class of relevant        Product           Exercising/          Number of         Exercise price 
    security           description      exercised against       securities           per unit 
                     e.g. call option 
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(d)     Other dealings (including subscribing for new securities) 
 
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 Class of relevant           Nature of dealing                Details          Price per unit (if 
      security         e.g. subscription, conversion                               applicable) 
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4.      OTHER INFORMATION 
 
(a)     Indemnity and other dealing arrangements 
 

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