RNS Number:5399M
Arana Therapeutics Limited
25 January 2008


For Immediate Release                                            25 January 2008

                           Arana Therapeutics Limited
                          Notification of Shareholding

Arana Therapeutics Limited, (AIM: AAHx ASX: AAH) (the "Company"), the Australian
biopharmaceutical company that uses superior technology to develop next
generation drugs that will improve the lives of patients with inflammatory
diseases and cancer has identified on 24 January 2008 that with effect from 23
January 2008, Rockwell Securities Limited increased its holding by 6,673,116
ordinary shares to 18,361,279 (7.8% of the issued share capital of the Company)
ordinary shares in the capital of the Company.

For further information, please contact:

Arana Therapeutics Limited
Dr John Chiplin, Chief Executive Officer                      +61 (0)2 8061 9900
Niall Henderson, Chief Financial Officer                      +61 (0)2 8061 9900

Buchanan Communication
Lisa Baderoon/Rebecca Skye Dietrich                          +44 (0)20 7466 5000
                                                                          
Nomura Code Securities
Charles Walker                                               +44 (0)20 7776 1206
                                                                          


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            The company news service from the London Stock Exchange
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