Skyline.R8RS
1年前
The need for quick and accurate infectious disease diagnosis will facilitate the use of new techniques such as “syndromic infectious disease testing”. Rather than looking for and isolating certain pathogens individually, syndromic infectious disease testing examines a wide range of clinical “syndromes,” or symptoms, to identify an infectious disease.
Traditional tests often calls for long lab analyses, and can only identify one pathogen at a time. On the other hand, syndromic infectious disease tests such as Multiplex PCR (mPCR) can correctly identify the genetic material of numerous pathogens in a much shorter time frame, granting physicians a much faster and more precise infectious disease diagnostic tool.
The Multiplex PCR Tests that Cue Health is developing and soon to offer; including Flu + RSV + COVID; Chlamydia + Gonorrhea; Herpes + Mpox; that can accurately determine the genetic code of numerous pathogens for syndromic testing; will allow physicians to deploy more accurate treatments, which can significantly reduce infectious disease severity.
Skyline.R8RS
1年前
New e-commerce channels especially for high-growth healthcare products and services sector are rapidly evolving as indicated by Walmart and Amazon among a larger pipeline of retailer-to-healthcare providers that has grown in the last few years. Pharmacy chains such as CVS and Walgreens are a few others that have greatly invested in becoming primary care providers. Amazon in particular has made significant moves forward toward becoming a key player in the healthcare industry, inspire of the fact withdrawing “Amazon Care” in late 2022, it came back in early 2023 and bought out One Medical for almost $4 billion. Meanwhile Walmart has also made progress toward becoming a major provider in this market, launching brick-and-mortar clinics across American with the objective of becoming the “neighborhood health destination”, with plans to add 28 new locations in 2024, and in talks to purchase a majority stake in ChenMed, a primary care provider. Providing the backbone of such enterprises are healthcare e-commerce platforms such as NextPlat Corp, which is helping to popularize virtual healthcare and which could result in the majority of the population preferring to access all the healthcare services and products that they need via the internet. Noteworthy is Cue Health’s presence in the Telehealth and healthcare e-commerce with its Cue Care and Cue Pharmacy. A buy-out candidate for one of these large retailers?
Skyline.R8RS
1年前
The World Health Organization is monitoring a surge of respiratory illnesses among children in China, that Chinese health authorities reported are “due to Mycoplasma pneumoniae pneumonia since May, and RSV, adenovirus and influenza virus since October”; and attributed to the increase in respiratory diseases with the lifting of COVID-19 restrictions, as the country is in its first full winter without such restrictions. At the same time in the US, the CDC reports that “only 14% of Americans have received the latest COVD-19 vaccine”, which is below where the agency would like vaccine uptake to be. "Here's the bottom line: COVID-19 vaccine uptake is lower than we'd like to see, and most people will be without the added protection that can reduce the severity of COVID-19," the agency stated.
Skyline.R8RS
1年前
There is no question that the Cue Health Monitoring System is best-in-class POCT device available on the market today. However Cue Health can not achieve a global market reach unless it has a product offering closer to the World Health Organization (WHO) guidelines for “ASSURED” - affordable and off-the-shelf, sensitive, specific, user friendly, reliable, efficient and time-saving; field deployable; and most significantly, instrument-free with no external electrical and optical system requirement, POC device. The broadly available paper-based NAAT devices do meet most of the ASSURED criteria, they are inexpensive, easily disposable, responsive to biomolecule conformations and interactions, and are good sample and reagent carriers, making them ideal substrates for use in remote and resource-poor setting. It is possible to envision developing an integrated paper/membrane based microfluidic device for instrument-free RNA isolation, reverse transcription, amplification and detection that can be performed at room temperature. The successful development of this type of PRT device by Cue Health, either through partnership, acquisition, licensing is a step forward towards the goal of developing a complete instrument-free integrated NAAT system for POC diagnosis that can have broad global market reach and establish preeminent brand recognition with full product complement.
Skyline.R8RS
1年前
I have the Cue Reader and Cue Covid Test Cartridges and its a breeze to use: and with no contact with the buffer, reagent, or reaction chamber and nothing to “mess-up”; nicely designed and manufactured; and with a great interaction app; and made with “Apple-like” packaging presentation. However just like Apple, its expensive, and I use it sparingly, preferring to get the cheaper “antigen” LFT strips, with no brand preferences other than the “free ones” when they were available or the “cheap ones” to stock up when they go on sale at the local chain drug store.
This is a great POCT machine and with a strong value proposition for institutions. However the private consumer is being left behind (and as such money left on the table) The future of diagnostic testing for this segment of the market is going to depend on innovative electromechical design, for "entirely self-contained and disposable" OTC and advance "next generation" chemistry to allow AMBIENT and NEAR INSTANTANEOUS REACTIONS, BATTERY POWERED, AND EASY TO READ. Start-ups and their backers are rushing to get this done, and sometimes with Gates Foundation Grants where they are willing to give up a portion of the global market (with “open-access” and global licensing agreements). I am anxiously awaiting for something like this (before the competition sweeps past with a low COGS personal consumer product with):
No instrument or reader;
No external power supply;
Results shown on a high-contrast display.
Maybe a “partnering deal”?
Skyline.R8RS
1年前
Lets stop for a moment and recognized what has transpired, prior to COVID-19 you could only test for HIV at home, and approval was a 10-year process. The next phase of this, is now taking the momentum for COVID-19 home testing with EUA's, and appyling it to a broader range of issues, a broader range of pathogens; and with 510K's (substantially equivalent) and De Novo (not present substantial risk to user/patient) approvals now taking months instead of years (as with a PMA). Out of necessity came reform and now a sweet spot for Cue and with that has an overwhelming advantage!
Skyline.R8RS
1年前
A TIME article on Sept 25 titled “Is It Flu, COVID-19, or RSV? How to Navigate the New World of At-Home Testing” speaks about the criticality of figuring out whether a sore throat, fever, and runny nose were caused by a cold, flu, strep, or COVID infection (and need to limit spread); and makes mention of Cue Health’s products (although with some misinformation). At this time, Flu A/B, RSV, COVID Multiplex Molecular Tests are "deep" in FDA approval reviews!
Skyline.R8RS
1年前
TD Cowen just reduced target from $5 to $1.50 and near-term that’s about right. Its not a sprint, its a marathon, and now post-pandemic adoption is about alignment of clinicians, payers, and the patient; and workflow changes. Right now Cue is nibbling away on the outside for specific demographic and use case(s). Patients will always want something that is coordinated and aligned; and will not give up the face-to-face therapeutic alliance for a faceless app. So Cue’s next leg of the journey is its part in making that encounter more meaningful, more efficient and more engaging; and help answer for the provider: “out of the 1000’s of patients who should come in?”. This will come as Cue’s technology is deployed for evidence-based guidelines, with “numbers that don’t lie”; and create a next generation of care experiences; that allows for patients to be in control of their data and for providers to intervene earlier, and prevent more costly outcomes (and this payers will embrace)!
Skyline.R8RS
1年前
The need for quick and accurate infectious disease diagnosis will facilitate the use of new techniques such as “syndromic infectious disease testing”. Rather than looking for and isolating certain pathogens individually, syndromic infectious disease testing examines a wide range of clinical “syndromes,” or symptoms, to identify an infectious disease.
Traditional tests often calls for long lab analyses, and can only identify one pathogen at a time. On the other hand, syndromic infectious disease tests such as Multiplex PCR (mPCR) can correctly identify the genetic material of numerous pathogens in a much shorter time frame, granting physicians a much faster and more precise infectious disease diagnostic tool.
The Multiplex PCR Tests that Cue Health is developing and soon to offer; including Flu + RSV + COVID; Chlamydia + Gonorrhea; Herpes + Mpox; that can accurately determine the genetic code of numerous pathogens for syndromic testing; will allow physicians to deploy more accurate treatments, which can significantly reduce infectious disease severity.
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