(Updates with comment from U.S. Department of Justice.)

By Simon Zekaria

LONDON--Anheuser-Busch InBev NV (BUD, ABI.BT) agreed to give up key U.S. assets and beer licenses of Grupo Modelo SAB (GPMCY, GMODELO.MX) worth $4.75 billion to fend off U.S. antitrust regulators and push through its $20.1 billion takeover of the Mexican brewer.

AB InBev, the world's biggest beer maker by revenue, will grant perpetual rights for the popular Corona and Modelo lager brands in the U.S., as well as sell its Piedras Negras bottling factory in Mexico, to U.S.-based Constellation Brands Inc. (STZ, STZB), the No. 1 wine group, for a total of $2.9 billion.

AB InBev will also sell Modelo's 50% stake in Crown Imports, a U.S. beer importer and distributor, to its joint-venture partner Constellation for $1.85 billion, the companies said.

Leuven, Belgium-based AB InBev already owns 50% of Modelo, but at the end of last month the U.S. government filed a lawsuit seeking to block a full takeover. Regulators are concerned the deal would restrict competition and push up prices for beer drinkers, amid growing big-brewer dominance in the mainstream lager market.

"I can't comment on a specific proposal. However, we would give any proposal serious consideration and at the same time we would continue to prepare for litigation," said Gina Talamona, a spokeswoman for the U.S. Department of Justice in Washington, D.C.

Under the original terms of the deal, AB InBev had an option to buy the U.S. rights for all Modelo brands after 10 years. AB InBev had previously said it would sell Modelo's half stake in Crown to Constellation, but regulators said the arrangement wasn't satisfactory because Constellation would still rely on AB InBev for its beer supply.

On Thursday, AB InBev said the brewery sale--located near the Texas border to supply of the U.S. beer market--would ensure independence of supply for Crown, and gives Constellation "complete control" of the production and distribution of Modelo brands. Constellation, which also sells liquor, will invest about $400 million over three years to expand the brewery's capacity, which currently accounts for 60% of Crown's demand.

The U.S. beer marker, at around 250 million hectoliters, is second only to China as the world's largest by volume. It is largely dominated by AB InBev, owner of Bud Light and Budweiser, and MillerCoors, maker of the Coors Light brand, which together accounted for more than 80% of U.S. beer profits in 2011, according to Bernstein Securities data. While Corona is the best-selling imported beer in the U.S., Modelo has a much smaller presence with around a mid-single-digit percentage share of sales. Together, AB InBev and Modelo would control just under half of U.S. beer sales.

Analysts welcomed Thursday's agreement between AB InBev and Constellation, but remained cautious on whether the brokered deal will appease the U.S. Department of Justice.

"The fact that Crown now would become a stronger independent competitor...could be a game changer," said Bank Degroof's Hans D'Haese. Crown would become the No. 3 producer and marketer of beer in the U.S. under the revised offer, AB InBev said.

"[It] is a move in the right direction. But will it be sufficient?" Mr. D'Haese said.

Liberum capital analyst Pablo Zuanic noted the speed of the revised deal would please industry watchers. "The quick settlement is no doubt surprising, but also shows practicality from the AB InBev side."

AB InBev made a play for the half of Modelo it didn't own in June last year, in a bid both to bolster its position across Mexico's fast-growing beer market and to add Corona, a pale lager usually drunk with a wedge of lemon or lime, to its stable of top-selling brands.

The company is benefiting from strong demand for premium beer in Latin America and Asia, where increasing adult populations and rising incomes are driving consumption. But despite the recent modest recovery seen in the U.S. beer market, the company's high exposure to a country where consumers have been cutting spending on lager means it has looked elsewhere to diversify its risk across global beer markets.

Just two months before its proposal for Modelo, the maker of Brazilian lager Brahma forked out $1.24 billion for a majority stake in Dominican brewer Cerveceria Nacional Dominicana (CCN.GU).

Write to Simon Zekaria at simon.zekaria@dowjones.com

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