By Anthony O. Goriainoff

 

AstraZeneca PLC said Monday that the U.S. Food and Drug Administration approved its Imjudo treatment in combination with Imfinzi for patients with liver cancer when surgery isn't an option as treatment.

The London-listed pharmaceutical company said the approval was based on positive results from the Himalaya Phase 3 trial.

Patients in the trial treated with the combination of Imjudo and Imfinzi experienced a 22% reduction in the risk of death versus sorafenib, AstraZeneca said. It added that around 31% of patients were still alive after three years compared with 20% of patients treated with sorafenib still alive at the same duration of follow-up.

The Anglo-Swedish pharma giant said regulatory applications for Imjudo in combination with Imfinzi are currently under review in Europe, Japan and several other countries.

 

Write to Anthony O. Goriainoff at anthony.orunagoriainoff@dowjones.com

 

(END) Dow Jones Newswires

October 24, 2022 02:35 ET (06:35 GMT)

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